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Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 5
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Research Article

Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1

D. D. Surry Departments of Drug Metabolism and Pharmacokinetics, OE Pharmacology and, Neuroscience Research Centre, Merck Research Laboratories, Harlow, UK
,
G. Meneses-Lorente Departments of Drug Metabolism and Pharmacokinetics, OE Pharmacology and, Neuroscience Research Centre, Merck Research Laboratories, Harlow, UK
,
R. Heavens Departments of Drug Metabolism and Pharmacokinetics, OE Pharmacology and, Neuroscience Research Centre, Merck Research Laboratories, Harlow, UK
,
A. Jack Departments of Drug Metabolism and Pharmacokinetics, OE Pharmacology and, Neuroscience Research Centre, Merck Research Laboratories, Harlow, UK
&
D. C. Evans Departments of Drug Metabolism and Pharmacokinetics, OE Pharmacology and, Neuroscience Research Centre, Merck Research Laboratories, Harlow, UK
Pages 441-456 | Published online: 22 Sep 2008

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Helen Garside, Allison Stewart, Nick Brown, Emma-Louise Cooke, Mark Graham & Michael Sullivan. (2008) Quantitative analysis of aryl hydrocarbon receptor activation using fluorescence-based cell imaging—A high-throughput mechanism-based assay for drug discovery. Xenobiotica 38:1, pages 1-20.
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H. A. Barton, J. Tang, H. A. Barton, J. Tang, Y. M. Sey, J. P. Stanko, R. N. Murrell, H. A. Barton, J. Tang, Y. M. Sey, J. P. Stanko, R. N. Murrell, J. C. Rockett, H. A. Barton, J. Tang, Y. M. Sey, J. P. Stanko, R. N. Murrell, J. C. Rockett & D. J. Dix. (2006) Metabolism of myclobutanil and triadimefon by human and rat cytochrome P450 enzymes and liver microsomes. Xenobiotica 36:9, pages 793-806.
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Articles from other publishers (3)

Jong Min Choi, Soo Jin Oh, Sang Yoon Lee, Ji Hye Im, Jung Min Oh, Chang Seon Ryu, Hui Chan Kwak, Ji-Yoon Lee, Keon Wook Kang & Sang Kyum Kim. (2014) HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics. Archives of Pharmacal Research 38:5, pages 691-704.
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Lucie Bořek-Dohalská, Petra Valášková, Věra Černá & Marie Stiborová. (2014) Role of rat cytochromes P450 in the oxidation of 17α-ethinylestradiol. Environmental Toxicology and Pharmacology 38:3, pages 852-860.
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Jeffrey F. Waring, Rita Ciurlionis, Robert A. Jolly, Matthew Heindel & Roger G. Ulrich. (2001) Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicology Letters 120:1-3, pages 359-368.
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