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Xenobiotica
the fate of foreign compounds in biological systems
Volume 34, 2004 - Issue 8
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Research Article

Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus

J. R. Fry School of Biomedical Sciences, Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UKCorrespondence[email protected]
,
A. H. Hammond School of Biomedical Sciences, Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK
,
K. L. Jassi School of Biomedical Sciences, Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK
,
A. E. Bass School of Biomedical Sciences, Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK
,
G. Bruce School of Biomedical Sciences, Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK
,
C. Laughton School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
,
P. N. Shaw School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
,
I. E. Bylov Department of Organic Chemistry, National University of Pharmacy, Kharkov 61002, Ukraine
&
S. M. Kovalenko Department of Organic Chemistry, National University of Pharmacy, Kharkov 61002, Ukraine
 show all
Pages 707-722 | Received 10 Apr 2004, Published online: 22 Sep 2008

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David FV Lewis, Yuko Ito & Brian G Lake. (2010) Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences. Journal of Enzyme Inhibition and Medicinal Chemistry 25:5, pages 679-684.
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Sergiy M. Kovalenko, Sergiy V. Vlasov, Olexiy V. Silin & Valentin P. Chernykh. (2009) Recyclization of 2-imino-2H-1-benzopyrans under the action of nucleophilic reagents: the novel approach for 2-(coumarin-3-yl)-3H-quinazolin-4-thiones. Journal of Sulfur Chemistry 30:1, pages 53-63.
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Articles from other publishers (2)

Gong-Jhe Wu, Yung-Wei Lin, Hsiao-Chien Tsai, Yuan-Wen Lee, Jui-Tai Chen & Ruei-Ming Chen. (2018) Sepsis-induced liver dysfunction was ameliorated by propofol via suppressing hepatic lipid peroxidation, inflammation, and drug interactions. Life Sciences 213, pages 279-286.
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Xiu-hong Liu, Ji-cai Fan, Yang Liu & Zhi-cai Shang. (2008) L-Proline as an efficient and reusable promoter for the synthesis of coumarins in ionic liquid. Journal of Zhejiang University SCIENCE B 9:12, pages 990-995.
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