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Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 2
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Research Article

Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine

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Pages 169-179 | Received 22 Feb 2006, Accepted 27 Mar 2006, Published online: 22 Sep 2008

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C. B. Eap, G. Gründer, P. Baumann, N. Ansermot, A. Conca, E. Corruble, S. Crettol, M. L. Dahl, J. de Leon, C. Greiner, O. Howes, E. Kim, R. Lanzenberger, J. H. Meyer, R. Moessner, H. Mulder, D. J. Müller, M. Reis, P. Riederer, H. G. Ruhe, O. Spigset, E. Spina, B. Stegman, W. Steimer, J. Stingl, S. Suzen, H. Uchida, S. Unterecker, F. Vandenberghe & C. Hiemke. (2021) Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants. The World Journal of Biological Psychiatry 22:8, pages 561-628.
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Alfredo Carlo Altamura, Alice Caldiroli & Massimiliano Buoli. (2015) Pharmacokinetic evaluation of fluvoxamine for the treatment of anxiety disorders. Expert Opinion on Drug Metabolism & Toxicology 11:4, pages 649-660.
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Articles from other publishers (16)

Khairulanwar Burhanuddin & Raj Badhan. (2022) Optimising Fluvoxamine Maternal/Fetal Exposure during Gestation: A Pharmacokinetic Virtual Clinical Trials Study. Metabolites 12:12, pages 1281.
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Michael Zastrozhin, Valentin Skryabin, Valeriy Smirnov, Anastasiya Zastrozhina, Elena Grishina, Kristina Ryzhikova, Irina Bure, Pavel Golovinskii, Sergey Koporov, Evgeniy Bryun & Dmitry Sychev. (2022) Effect of Genetic Polymorphism of the CYP2D6 Gene on the Efficacy and Safety of Fluvoxamine in Major Depressive Disorder. American Journal of Therapeutics 29:1, pages e26-e33.
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Gianluca Catucci, Gianfranco Gilardi & Sheila J. Sadeghi. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 509 562 .
Li Di, Amanda Balesano, Samantha Jordan & Sophia M. Shi. (2021) The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation. The AAPS Journal 23:1.
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Yoichi Tanikawa, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Kumiko Kitta, Kiyotaka Hoshiai, Hiroko Izumi-Nakaseko, Atsuhiko T. Naito & Atsushi Sugiyama. (2019) Characterization of microminipig as a laboratory animal for safety pharmacology study by analyzing fluvoxamine-induced cardiovascular and dermatological adverse reactions. Cardiovascular Toxicology 19:5, pages 412-421.
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Marc Augustin, Georgios Schoretsanitis, Philippe Pfeifer, Gerhard Gründer, Claus Liebe & Michael Paulzen. (2019) Effect of fluvoxamine augmentation and smoking on clozapine serum concentrations. Schizophrenia Research 210, pages 143-148.
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Hui Li, Erica Toth & Nathan J Cherrington. (2018) Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis. Toxicological Sciences 164:2, pages 428-438.
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Vincent A. de Weger, Sanjay Goel, Roger von Moos, Jan H. M. Schellens, Nicholas Mach, Eugene Tan, Suraj Anand, Jeffrey W. Scott & Ulrik Lassen. (2017) A drug–drug interaction study to assess the effect of the CYP1A2 inhibitor fluvoxamine on the pharmacokinetics of dovitinib (TKI258) in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology 81:1, pages 73-80.
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Saeed Alqahtani & Amal Kaddoumi. (2016) Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs. Clinical Pharmacokinetics 55:8, pages 957-969.
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Lingtak-Neander Chan & Gail D. Anderson. (2014) Pharmacokinetic and Pharmacodynamic Drug Interactions with Ethanol (Alcohol). Clinical Pharmacokinetics 53:12, pages 1115-1136.
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Xingxing Diao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 4 .
Xingxing Diao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 5 .
Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang & Xiaoyan Chen. (2013) Metabolism and Pharmacokinetics of 3- n -Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation . Drug Metabolism and Disposition 41:2, pages 430-444.
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Yumiko Akamine, Norio Yasui-Furukori, Ichiro Ieiri & Tsukasa Uno. (2012) Psychotropic Drug–Drug Interactions Involving P-Glycoprotein. CNS Drugs 26:11, pages 959-973.
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J. L. Pilgrim, D. Gerostamoulos & Olaf H. Drummer. (2010) Review: Pharmacogenetic aspects of the effect of cytochrome P450 polymorphisms on serotonergic drug metabolism, response, interactions, and adverse effects. Forensic Science, Medicine, and Pathology 7:2, pages 162-184.
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Yasuhiro Katoh, Shinya Uchida, Masayoshi Kawai, Noriyoshi Takei, Norio Mori, Junichi Kawakami, Yoshiyuki Kagawa, Shizuo Yamada, Noriyuki Namiki & Hisakuni Hashimoto. (2010) Effects of Cigarette Smoking and Cytochrome P450 2D6 Genotype on Fluvoxamine Concentration in Plasma of Japanese Patients. Biological & Pharmaceutical Bulletin 33:2, pages 285-288.
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