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Xenobiotica

the fate of foreign compounds in biological systems

Volume 48, 2018 - Issue 7

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Xenobiotic Transporters

Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro

Lucie NavrátilováDepartment of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

Jana Ramos MandíkováDepartment of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

Petr PávekDepartment of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

Přemysl MladěnkaDepartment of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

František TrejtnarDepartment of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech RepublicCorrespondence[email protected]

Pages 745-755 | Received 22 May 2017, Accepted 18 Jul 2017, Published online: 18 Aug 2017

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https://doi.org/10.1080/00498254.2017.1358469
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Aleksandra Duda-Chodak & Tomasz Tarko. (2023) Possible Side Effects of Polyphenols and Their Interactions with Medicines. Molecules 28:6, pages 2536.
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Marilyn E. Morris & Tianjing Ren. 2022. Drug Transporters. Drug Transporters 515 541 .

Anima M. Schäfer, Pierrine M. Gilgen, Clara Spirgi, Olivier Potterat & Henriette E. Meyer zu Schwabedissen. (2021) Constituents of Passiflora incarnata, but Not of Valeriana officinalis, Interact with the Organic Anion Transporting Polypeptides (OATP)2B1 and OATP1A2. Planta Medica 88:02, pages 152-162.
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Song Gao, Nyma Siddiqui, Imoh Etim, Ting Du, Yun Zhang & Dong Liang. (2021) Developing nutritional component chrysin as a therapeutic agent: Bioavailability and pharmacokinetics consideration, and ADME mechanisms. Biomedicine & Pharmacotherapy 142, pages 112080.
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Anna Raguzzini, Elisabetta Toti, Maura Palmery, Mohamed M. Abdel-Daim & Ilaria Peluso. (2021) Dietary Habits and Musculoskeletal Pain in Statin and Red Yeast Rice Users: A Pilot Study. European Journal of Investigation in Health, Psychology and Education 11:4, pages 1156-1165.
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Anima M. Schäfer, Henriette E. Meyer zu Schwabedissen & Markus Grube. (2021) Expression and Function of Organic Anion Transporting Polypeptides in the Human Brain: Physiological and Pharmacological Implications. Pharmaceutics 13:6, pages 834.
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Patrick T. Ronaldson, Hrvoje Brzica, Wazir Abdullahi, Bianca G. Reilly & Thomas P. Davis. (2021) Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- β Signaling in Human Endothelial Cells . Journal of Pharmacology and Experimental Therapeutics 376:2, pages 148-160.
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Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka & Miklós Poór. (2020) Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters. Drug Metabolism and Disposition 48:10, pages 1064-1073.
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Xunkai Lin, Zhaojian Xiang, Bo Wang, Hong Chen, Tong Zhou & Mei Hong. (2019) Interaction of swine organic anion transporting polypeptide 1a2 with tetracycline, macrolide and β-lactam antibiotics. Toxicology and Applied Pharmacology 379, pages 114649.
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Xiaoling Shen, Yeju Liu, Xiaoya Luo & Zhihong Yang. (2019) Advances in Biosynthesis, Pharmacology, and Pharmacokinetics of Pinocembrin, a Promising Natural Small-Molecule Drug. Molecules 24:12, pages 2323.
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Lucie Navrátilová, Lenka Applová, Pavel Horký, Přemysl Mladěnka, Petr Pávek & František Trejtnar. (2018) Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter. Naunyn-Schmiedeberg's Archives of Pharmacology 391:10, pages 1063-1071.
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Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro

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Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro

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