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Xenobiotica
the fate of foreign compounds in biological systems
Volume 48, 2018 - Issue 9
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General Xenobiochemistry

The effects of UDP-sugars, UDP and Mg2+on uridine diphosphate glucuronosyltransferase activity in human liver microsomes

Gurinder WaliaFaculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada
,
Alexander D. SmithFaculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada
,
Zoe RichesFaculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada
,
Abby C. CollierFaculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada
&
Michael W. H. CoughtrieFaculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, CanadaCorrespondence[email protected]
Pages 882-890 | Received 14 Jul 2017, Accepted 02 Sep 2017, Published online: 26 Sep 2017

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Vera Helena V. Dias, Jacó J. Mattos, Camila L. V. Bastolla, Karim H. Lüchmann & Afonso C. D. Bainy. (2022) Characterisation of UDP-glucuronosyltransferase activity in sea turtle Chelonia mydas. Xenobiotica 52:12, pages 1011-1019.
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Articles from other publishers (7)

Pablo J. Schwarzbaum, Julieta Schachter & Luis M. Bredeston. (2022) The broad range di- and tri-nucleotide exchanger SLC35B1 displays asymmetrical affinities for ATP transport across the ER membrane. Journal of Biological Chemistry 298:4, pages 101537.
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Jacqueline J Ehrlich, Richard M Weerts, Sayane Shome, Alan T Culbertson, Richard B Honzatko, Robert L Jernigan & Olga A Zabotina. (2021) Xyloglucan Xylosyltransferase 1 Displays Promiscuity Toward Donor Substrates During in Vitro Reactions. Plant and Cell Physiology 62:12, pages 1890-1901.
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John O. Miners, Andrew Rowland, Jonathan J. Novak, Kimberly Lapham & Theunis C. Goosen. (2021) Evidence-based strategies for the characterisation of human drug and chemical glucuronidation in vitro and UDP-glucuronosyltransferase reaction phenotyping. Pharmacology & Therapeutics 218, pages 107689.
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Jin Zhou, Upendra A. Argikar & John O. Miners. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 301 338 .
Shishir Sharma, Pradeepraj Durairaj & Matthias Bureik. (2020) Rapid and convenient biotransformation procedure for human drug metabolizing enzymes using permeabilized fission yeast cells. Analytical Biochemistry 607, pages 113704.
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Feng Zhao, Xi Wang, Yan Wang, Jingbo Zhang, Ran Lai, Bei Zhang & Xueyan Zhou. (2020) The function of uterine UDP-glucuronosyltransferase 1A8 (UGT1A8) and UDP-glucuronosyltransferase 2B7 (UGT2B7) is involved in endometrial cancer based on estrogen metabolism regulation. Hormones 19:3, pages 403-412.
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Justine Badée, Nahong Qiu, Neil Parrott, Abby C. Collier, Stephan Schmidt & Stephen Fowler. (2019) Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry. Drug Metabolism and Disposition 47:2, pages 124-134.
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