Citations (31)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Inge AM de Graaf, Geny MM Groothuis & Peter Olinga. (2007) Precision-cut tissue slices as a tool to predict metabolism of novel drugs. Expert Opinion on Drug Metabolism & Toxicology 3:6, pages 879-898.
Read now
Read now
K. Gross-Steinmeyer, P. L. Stapleton, F. Liu, J. H. Tracy, T. K. Bammler, S. D. Quigley, F. M. Farin, D. R. Buhler, S. H. Safe, S. C. Strom & D. L. Eaton. (2004) Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes. Xenobiotica 34:7, pages 619-632.
Read now
Read now
Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
Read now
Read now
B. G. Lake, S. E. Ball, J. Kao, A. B. Renwick, R. J. Price & J. A. Scatina. (2002) Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase. Xenobiotica 32:10, pages 835-847.
Read now
Read now
O. Pelkonen, P. Myllynen, P. Taavitsainen, A. R. Boobis, P. Watts, B. G. Lake, R. J. Price, A. B. Renwick, M.-J. Gómez-Lechón, J. V. Castell, M. Ingelman-Sundberg, M. Hidestrand, A. Guillouzo, L. Corcos, P. S. Goldfarb & D. F. V. Lewis. (2001) Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems. Xenobiotica 31:6, pages 321-343.
Read now
Read now
Articles from other publishers (26)
Florian Klomp, Christoph Wenzel, Marek Drozdzik & Stefan Oswald. (2020) Drug–Drug Interactions Involving Intestinal and Hepatic CYP1A Enzymes. Pharmaceutics 12:12, pages 1201.
Crossref
Crossref
Ying Xu, Lu Zhang, Kai-Ling Wang, Yu Zhang & Yue Him Wong. (2020) Transcriptomic analysis of the mode of action of the candidate anti-fouling compound di(1H-indol-3-yl)methane (DIM) on a marine biofouling species, the bryozoan Bugula neritina. Marine Pollution Bulletin 152, pages 110904.
Crossref
Crossref
Craig S. Charron, Janet A. Novotny, Elizabeth H. Jeffery, Matthew Kramer, Sharon A. Ross & Harold E. Seifried. (2020) Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial. Journal of Functional Foods 64, pages 103624.
Crossref
Crossref
Renata Mozrzymas, Monika Dus-Zuchowska, Lukasz Kaluzny, Anna Miskiewicz-Chotnicka, Aleksandra Lisowska & Jaroslaw Walkowiak. (2017) Microsomal Liver Function in Patients with Phenylketonuria Assessed by 13C-Methacetin Breath Test. Iranian Journal of Pediatrics 27:6.
Crossref
Crossref
E.H.J. Krekels, J.E. Rower, J.E. Constance, C.A.J. Knibbe & C.M.T. Sherwin. 2017. Drug Metabolism in Diseases. Drug Metabolism in Diseases
181
206
.
Satyanarayana R. Pondugula, Patrick C. Flannery, Kodye L. Abbott, Elaine S. Coleman, Sridhar Mani, Temesgen Samuel & Wen Xie. (2015) Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR. Toxicology Letters 232:3, pages 580-589.
Crossref
Crossref
Guy Haskin Fernald & Russ B. Altman. (2013) Using Molecular Features of Xenobiotics to Predict Hepatic Gene Expression Response. Journal of Chemical Information and Modeling 53:10, pages 2765-2773.
Crossref
Crossref
Alexander V. LyubimovCostas Ioannides & Brian G. Lake. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
26
.
V Perera, A S Gross & A J McLachlan. (2012) Influence of Environmental and Genetic Factors on CYP1A2 Activity in Individuals of South Asian and European Ancestry. Clinical Pharmacology & Therapeutics.
Crossref
Crossref
Sanjeev Banerjee, Dejuan Kong, Zhiwei Wang, Bin Bao, Gilda G. Hillman & Fazlul H. Sarkar. (2011) Attenuation of multi-targeted proliferation-linked signaling by 3,3′-diindolylmethane (DIM): From bench to clinic. Mutation Research/Reviews in Mutation Research 728:1-2, pages 47-66.
Crossref
Crossref
Sabrina Peterson, Yvonne Schwarz, Shuying S. Li, Lin Li, Irena B. King, Chu Chen, David L. Eaton, John D. Potter & Johanna W. Lampe. (2009)
CYP1A2, GSTM1
, and
GSTT1
Polymorphisms and Diet Effects on CYP1A2 Activity in a Crossover Feeding Trial
. Cancer Epidemiology, Biomarkers & Prevention 18:11, pages 3118-3125.
Crossref
Crossref
Jason R. Catania, Barbara P. McGarrigle, Kate Rittenhouse-Olson & James R. Olson. (2007) Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium. Toxicology in Vitro 21:1, pages 109-115.
Crossref
Crossref
Yixuan Gong, Gary L. Firestone & Leonard F. Bjeldanes. (2006) 3,3′-Diindolylmethane Is a Novel Topoisomerase IIα Catalytic Inhibitor That Induces S-Phase Retardation and Mitotic Delay in Human Hepatoma HepG2 Cells. Molecular Pharmacology 69:4, pages 1320-1327.
Crossref
Crossref
Ole Vang. 2005. Carcinogenic and Anticarcinogenic Food Components. Carcinogenic and Anticarcinogenic Food Components.
Xiaoming Cui, Ann Thomas, Yi Han, Jairam Palamanda, Diana Montgomery, Ronald E. White, Richard A. Morrison & K.-C. Cheng. (2005) Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo. Journal of Pharmacological and Toxicological Methods 52:2, pages 234-243.
Crossref
Crossref
Jarmo S. Salonen, Leena Nyman, Alan R. Boobis, Robert J. Edwards, Patricia Watts, Brian G. Lake, Roger J. Price, Anthony B. Renwick, Maria-José Gómez-Lechón, José V. Castell, Magnus Ingelman-Sundberg, Mats Hidestrand, Andre Guillouzo, Laurent Corcos, Peter S. Goldfarb, David F.V. Lewis, Päivi Taavitsainen & Olavi Pelkonen. (2003) COMPARATIVE STUDIES ON THE CYTOCHROME P450-ASSOCIATED METABOLISM AND INTERACTION POTENTIAL OF SELEGILINE BETWEEN HUMAN LIVER-DERIVED IN VITRO SYSTEMS. Drug Metabolism and Disposition 31:9, pages 1093-1102.
Crossref
Crossref
Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence Gan, Scott Grimm, John Kao, S. Peter King, Gerald Miwa, Lan Ni, Gondi Kumar, James McLeod, R. Scott Obach, Stanley Roberts, Amy Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, Jose M. Vega, John Walsh & Steven A. Wrighton. (2003) THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE. Drug Metabolism and Disposition 31:7, pages 815-832.
Crossref
Crossref
Esther F.A Brandon, Christiaan D Raap, Irma Meijerman, Jos H Beijnen & Jan H.M Schellens. (2003) An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons. Toxicology and Applied Pharmacology 189:3, pages 233-246.
Crossref
Crossref
Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf, Volker Fischer, Lawrence Gan, Scott Grimm, John Kao, S. Peter King, Gerald Miwa, Lan Ni, Gondi Kumar, James McLeod, Scott R. Obach, Stanley Roberts, Amy Roe, Anita Shah, Fred Snikeris, John T. Sullivan, Donald Tweedie, Jose M. Vega, John Walsh & Steven A. Wrighton. (2003) The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective. The Journal of Clinical Pharmacology 43:5, pages 443-469.
Crossref
Crossref
Robert J. Edwards, Roger J. Price, Patricia S. Watts, Anthony B. Renwick, J. Michael Tredger, Alan R. Boobis & Brian G. Lake. (2003) Induction of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices. Drug Metabolism and Disposition 31:3, pages 282-288.
Crossref
Crossref
B.G Lake, A.J Edwards, R.J Price, B.J Phillips, A.B Renwick, J.A Beamand & T.B Adams. (2001) Lack of effect of furfural on unscheduled DNA synthesis in the in vivo rat and mouse hepatocyte DNA repair assays and in precision-cut human liver slices. Food and Chemical Toxicology 39:10, pages 999-1011.
Crossref
Crossref
Adam D. Shilling, David B. Carlson, Sirinmas Katchamart & David E. Williams. (2001) 3,3′-Diindolylmethane, a Major Condensation Product of Indole-3-carbinol, Is a Potent Estrogen in the Rainbow Trout. Toxicology and Applied Pharmacology 170:3, pages 191-200.
Crossref
Crossref
Carole Lerche-Langrand & Herve J. Toutain. (2000) Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology. Toxicology 153:1-3, pages 221-253.
Crossref
Crossref
Sandra CoeckeVera RogiersMartin BaylissJosé CastellJohannes DoehmerGérard FabreJeffrey FryArmin Kern & Carl Westmoreland. (2019) The use of Long-term Hepatocyte Cultures for Detecting Induction of Drug Metabolising Enzymes: The Current Status. Alternatives to Laboratory Animals 27:4, pages 579-638.
Crossref
Crossref
A.B. Renwick, H. Mistry, P.T. Barton, F. Mallet, R.J. Price, J.A. Beamand & B.G. Lake. (1999) Effect of some Indole Derivatives on Xenobiotic Metabolism and Xenobiotic-induced Toxicity in Cultured Rat Liver Slices. Food and Chemical Toxicology 37:6, pages 609-618.
Crossref
Crossref
Adam T. Drahushuk, Barbara P. McGarrigle, Brian P. Slezak, John J. Stegeman & James R. Olson. (1999) Time- and Concentration-Dependent Induction of CYP1A1 and CYP1A2 in Precision-Cut Rat Liver Slices Incubated in Dynamic Organ Culture in the Presence of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. Toxicology and Applied Pharmacology 155:2, pages 127-138.
Crossref
Crossref