Citations (32)
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Read on this site (8)
Yasuhiro Uno, Kazuhide Iwasaki, Hiroshi Yamazaki & David R. Nelson. (2011) Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function. Drug Metabolism Reviews 43:3, pages 346-361.
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Y. Uno, T. Kumano, G. Kito, R. Nagata, T. Kamataki & H. Fujino. (2007) CYP2C76-mediated species difference in drug metabolism: A comparison of pitavastatin metabolism between monkeys and humans. Xenobiotica 37:1, pages 30-43.
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I. Yamada, H. Fujino, S. Shimada & J. Kojima. (2003) Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans. Xenobiotica 33:7, pages 789-803.
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T. Niwa, T. Shiraga, S. Yamasaki, K. Ishibashi, Y. Ohno & A. Kagayama. (2003) In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes. Xenobiotica 33:7, pages 717-729.
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S. Dragoni, L. Bellik, M. Frosini, G. Sgaragli, S. Marini, P. G. Gervasi & M. Valoti. (2003) l -Deprenyl metabolism by the cytochrome P450 system in monkey (Cercopithecus aethiops) liver microsomes. Xenobiotica 33:2, pages 181-195.
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R. J. Weaver. (2001) Assessment of drug-drug interactions: concepts and approaches. Xenobiotica 31:8-9, pages 499-538.
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N. J. Hewitt, T. Fischer, U. Zuehlke, F. Oesch & D. Utesch. (2000) Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes. Xenobiotica 30:7, pages 665-681.
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J. J. P. Bogaards, M. Bertrand, P. Jackson, M. J. Oudshoorn, R. J. Weaver, P. J. Van Bladeren & B. Walther. (2000) Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man. Xenobiotica 30:12, pages 1131-1152.
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Articles from other publishers (24)
Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary
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364
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Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki & Yasuhiro Uno. (2011) Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys. Journal of Pharmacology and Experimental Therapeutics 339:2, pages 654-661.
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Yasuhiro Uno, Kiyomi Matsuno, Norie Murayama, Chika Nakamura & Hiroshi Yamazaki. (2011) Metabolism of P450 Probe Substrates by Cynomolgus Monkey CYP2C76. Basic & Clinical Pharmacology & Toxicology 109:4, pages 315-318.
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Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. (2011) Discovery of Genetic Variants in CYP1D1: Implication for Functional Integrity of CYP1D1 in Cynomolgus Macaques and Rhesus Macaques. Drug Metabolism and Pharmacokinetics 26:6, pages 627-631.
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Yasuharu Nakanishi, Akinori Matsushita, Kiyomi Matsuno, Kazuhide Iwasaki, Masahiro Utoh, Chika Nakamura & Yasuhiro Uno. (2011) Regional Distribution of Drug-metabolizing Enzyme Activities in the Liver and Small Intestine of Cynomolgus Monkeys. Drug Metabolism and Pharmacokinetics 26:3, pages 288-294.
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Chie Emoto, Kazuhide Iwasaki, Ryo Koizumi, Masahiro Utoh, Norie Murayama, Yasuhiro Uno & Hiroshi Yamazaki. (2011) Species Difference between Cynomolgus Monkeys and Humans on Cytochromes P450 2D and 3A-Dependent Drug Oxidation Activities in Liver Microsomes. Journal of Health Science 57:2, pages 164-170.
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Yasuhiro Uno, Shotaro Uehara, Sakae Kohara, Norie Murayama & Hiroshi Yamazaki. (2010) Cynomolgus Monkey CYP2D44 Newly Identified in Liver, Metabolizes Bufuralol, and Dextromethorphan. Drug Metabolism and Disposition 38:9, pages 1486-1492.
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Yasuhiro UNOKiyomi MATSUNOChika NAKAMURAMasahiro UTOHHiroshi YAMAZAKI. (2010) Identification and Characterization of CYP2C18 in the Cynomolgus Macaque (Macaca fascicularis). Journal of Veterinary Medical Science 72:2, pages 225-228.
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Takeshi Shimizudani, Kenjiro Nagaoka, Nobumitsu Hanioka, Shigeru Yamano & Shizuo Narimatsu. (2010) Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys. Chemico-Biological Interactions 183:1, pages 67-78.
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Yasuhiro Uno, Tsukasa Ohuchi, Shotaro Uehara, Go Kito, Tetsuya Kamataki & Ryoichi Nagata. (2009)
Sex-Related Differences in the Expression of
mfGSTA2
, a Novel
GST
Identified in Cynomolgus Monkey (
Macaca fascicularis
)
. Drug Metabolism and Disposition 37:3, pages 453-456.
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Yasuhiro UNOKiyomi MATSUNOChika NAKAMURAMasahiro UTOHHiroshi YAMAZAKI. (2009) Identification and Characterization of CYP2B6 cDNA in Cynomolgus Macaques (Macaca fascicularis). Journal of Veterinary Medical Science 71:12, pages 1653-1656.
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Yasuhiro Uno, Hiroko Sakuraba, Shotaro Uehara, Takayuki Kumano, Kiyomi Matsuno, Chika Nakamura, Go Kito, Tetsuya Kamataki & Ryoichi Nagata. (2009)
A Null Allele Impairs Function of
CYP2C76
Gene in Cynomolgus Monkeys: A Possible Genetic Tool for Generation of a Better Animal Model in Drug Metabolism
. Drug Metabolism and Disposition 37:1, pages 14-17.
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Yasuhiro Uno, Yutaka Suzuki, Hiroyuki Wakaguri, Yoshiko Sakamoto, Hitomi Sano, Naoki Osada, Katsuyuki Hashimoto, Sumio Sugano & Ituro Inoue. (2008)
Expressed sequence tags from cynomolgus monkey (
Macaca fascicularis
) liver: A systematic identification of drug-metabolizing enzymes
. FEBS Letters 582:2, pages 351-358.
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Yasuhiro Uno, Shinya Hosaka, Kiyomi Matsuno, Chika Nakamura, Go Kito, Tetsuya Kamataki & Ryoichi Nagata. (2007) Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: Is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism?. Archives of Biochemistry and Biophysics 466:1, pages 98-105.
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Cuyue Tang, Yulin Fang, Catherine Booth-Genthe, Yuhsin Kuo, Scott D. Kuduk, Tom H. Rushmore & Brian A. Carr. (2007) Diclofenac hydroxylation in monkeys: Efficiency, regioselectivity, and response to inhibitors. Biochemical Pharmacology 73:6, pages 880-890.
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Masuhiro Nishimura, Akiko Koeda, Yasuyuki Suganuma, Emako Suzuki, Takefumi Shimizu, Mitsuo Nakayama, Tetsuo Satoh, Shizuo Narimatsu & Shinsaku Naito. (2007) Comparison of Inducibility of CYP1A and CYP3A mRNAs by Prototypical Inducers in Primary Cultures of Human, Cynomolgus Monkey, and Rat Hepatocytes. Drug Metabolism and Pharmacokinetics 22:3, pages 178-186.
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Yasuhiro Uno, Hideki Fujino, Go Kito, Tetsuya Kamataki & Ryoichi Nagata. (2006) CYP2C76, a Novel Cytochrome P450 in Cynomolgus Monkey, Is a Major CYP2C in Liver, Metabolizing Tolbutamide and Testosterone. Molecular Pharmacology 70:2, pages 477-486.
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David E. Amacher, Shelli J. Schomaker, Sherri E. Boldt & Michael Mirsky. (2006) The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies. Food and Chemical Toxicology 44:4, pages 528-537.
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Shizuo Narimatsu, Maiko Oda, Hiroyuki Hichiya, Takashi Isobe, Kazuo Asaoka, Nobumitsu Hanioka, Shigeru Yamano, Sumio Shinoda & Shigeo Yamamoto. (2005) Molecular cloning and functional analysis of cytochrome P450 1A2 from Japanese monkey liver: comparison with marmoset cytochrome P450 1A2. Chemico-Biological Interactions 152:1, pages 1-12.
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John R. Foster. (2016) Spontaneous and Drug-Induced Hepatic Pathology of the Laboratory Beagle Dog, the Cynomolgus Macaque and the Marmoset. Toxicologic Pathology 33:1, pages 63-74.
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Nicola J HewittDietmar Utesch. (2016) Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures. Human & Experimental Toxicology 23:6, pages 307-316.
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H. Fujino, T. Saito, Y. Tsunenari & J. Kojima. (2004) Effect of Gemfibrozil on the Metabolism of Pitavastatin - Determining the Best Animal Model for Human CYP And UGT Activities. Drug Metabolism and Drug Interactions 20:1-2.
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Eimear M. Ward, Malcolm R. Smyth, Richard O'Kennedy & Craig E. Lunte. (2003) Application of capillary electrophoresis with pH-mediated sample stacking to analysis of coumarin metabolites in microsomal incubations. Journal of Pharmaceutical and Biomedical Analysis 32:4-5, pages 813-822.
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Madeleine Nyman, Hannu Raunio, Päivi Taavitsainen & Olavi Pelkonen. (2001) Characterization of xenobiotic-metabolizing cytochrome P450 (CYP) forms in ringed and grey seals from the Baltic Sea and reference sites. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 128:1, pages 99-112.
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