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Kevin A. Ford, Gregory Ryslik, Jasleen Sodhi, Jason Halladay, Dolo Diaz, Donna Dambach & Melisa Masuda. (2015) Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications. Drug Metabolism Reviews 47:3, pages 291-319.
Read now
Read now
Shu-Feng Zhou, Bo Wang, Li-Ping Yang & Jun-Ping Liu. (2010) Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. Drug Metabolism Reviews 42:2, pages 268-354.
Read now
Read now
Shu-Feng Zhou, Jun-Ping Liu & Balram Chowbay. (2009) Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metabolism Reviews 41:2, pages 89-295.
Read now
Read now
Caitlin M. Brown, Brad Reisfeld & Arthur N. Mayeno. (2008) Cytochromes P450: A Structure-Based Summary of Biotransformations Using Representative Substrates. Drug Metabolism Reviews 40:1, pages 1-100.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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Articles from other publishers (30)
Yasushi Yamazoe & Kouichi Yoshinari. (2024) Construction of a fused grid-based CYP2C18-Template system and its application to drug metabolism. Drug Metabolism and Pharmacokinetics 54, pages 100534.
Crossref
Crossref
Yoshiya Yamamura, Kouichi Yoshinari & Yasushi Yamazoe. (2023) Construction of a fused grid-based CYP2C19-Template system and the application. Drug Metabolism and Pharmacokinetics 48, pages 100481.
Crossref
Crossref
Florian Klomp, Christoph Wenzel, Marek Drozdzik & Stefan Oswald. (2020) Drug–Drug Interactions Involving Intestinal and Hepatic CYP1A Enzymes. Pharmaceutics 12:12, pages 1201.
Crossref
Crossref
Wim Verlinden, Eugénie Van Mieghem, Laura Depauw, Thomas Vanwolleghem, Luisa Vonghia, Jonas Weyler, Ann Driessen, Dirk Callens, Laurence Roosens, Eveline Dirinck, An Verrijken, Luc Van Gaal & Sven Francque. (2020) Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis. Biomedicines 8:12, pages 546.
Crossref
Crossref
Ubaldina Galli, Gian Cesare Tron, Beatrice Purghè, Giorgio Grosa & Silvio Aprile. (2020) Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists?. Chemical Research in Toxicology 33:4, pages 955-966.
Crossref
Crossref
Silvio Aprile, Ubaldina Galli, Gian Cesare Tron, Erika Del Grosso, Cristina Travelli & Giorgio Grosa. (2020) Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. Data in Brief 28, pages 105034.
Crossref
Crossref
Peter Lykke Eriksen, Michael Sørensen, Henning Grønbæk, Stephen Hamilton-Dutoit, Hendrik Vilstrup & Karen Louise Thomsen. (2019) Non-alcoholic fatty liver disease causes dissociated changes in metabolic liver functions. Clinics and Research in Hepatology and Gastroenterology 43:5, pages 551-560.
Crossref
Crossref
E.T. Morgan. 2017. Drug Metabolism in Diseases. Drug Metabolism in Diseases
21
58
.
William D. Hedrich, Hazem E. Hassan & Hongbing Wang. (2016) Insights into CYP2B6-mediated drug–drug interactions. Acta Pharmaceutica Sinica B 6:5, pages 413-425.
Crossref
Crossref
Pieter M. M. De Kesel, Willy E. Lambert & Christophe P. Stove. (2015) Alternative Sampling Strategies for Cytochrome P450 Phenotyping. Clinical Pharmacokinetics 55:2, pages 169-184.
Crossref
Crossref
Toshiro Niwa, Mari Morimoto, Takako Hirai, Tomomi Hata, Misato Hayashi & Yurie Imagawa. (2016) Effect of penicillin-based antibiotics, amoxicillin, ampicillin, and piperacillin, on drug-metabolizing activities of human hepatic cytochromes P450. The Journal of Toxicological Sciences 41:1, pages 143-146.
Crossref
Crossref
Janne T. Backman, Anne M. Filppula, Mikko Niemi & Pertti J. Neuvonen. (2015) Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions. Pharmacological Reviews 68:1, pages 168-241.
Crossref
Crossref
Carmen Martínez, Inmaculada Andreu, Gemma Amo, Miguel A. Miranda, Gara Esguevillas, María José Torres, Natalia Blanca-López, Miguel Blanca, Elena García-Martín & José A.G. Agúndez. (2014) Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole. Biochemical Pharmacology 92:3, pages 457-466.
Crossref
Crossref
Alberto Massarotti, Silvio Aprile, Valentina Mercalli, Erika Del Grosso, Giorgio Grosa, Giovanni Sorba & Gian Cesare Tron. (2014) Are 1,4‐ and 1,5‐Disubstituted 1,2,3‐Triazoles Good Pharmacophoric Groups?. ChemMedChem 9:11, pages 2497-2508.
Crossref
Crossref
Kirsten E. Pijls, Hanne de Vries, Suzan Nikkessen, Aalt Bast, Will K. W. H. Wodzig & Ger H. Koek. (2014)
Critical appraisal of
13
C breath tests for microsomal liver function: aminopyrine revisited
. Liver International 34:4, pages 487-494.
Crossref
Crossref
Andrei A. Gilep, Tatyana A. Sushko & Sergey A. Usanov. (2011) At the crossroads of steroid hormone biosynthesis: The role, substrate specificity and evolutionary development of CYP17. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1814:1, pages 200-209.
Crossref
Crossref
Richard T. Mayer, E. Kurt Dolence & Gabriele E. Mayer. (2007)
A Real-Time Fluorescence Assay for Measuring
N
-Dealkylation
. Drug Metabolism and Disposition 35:1, pages 103-109.
Crossref
Crossref
Venkata Ramesh Dasari, Hindupur K. Anandatheerthavarada, Marie-Anne Robin, Ettickan Boopathi, Gopa Biswas, Ji-Kang Fang, Daniel W. Nebert & Narayan G. Avadhani. (2006) Role of Protein Kinase C-mediated Protein Phosphorylation in Mitochondrial Translocation of Mouse CYP1A1, Which Contains a Non-canonical Targeting Signal. Journal of Biological Chemistry 281:41, pages 30834-30847.
Crossref
Crossref
Edoardo G. Giannini, Vincenzo Savarino & Roberto Testa. (2006) Monitoring Cytochrome P-450 Activity During Rabeprazole Treatment in Patients with Gastresophageal Reflux Disease. Digestive Diseases and Sciences 51:9, pages 1602-1606.
Crossref
Crossref
Alison Li Lin, Nandita Shangari, Tom S. Chan, Diadelas Remirez & Peter J. O'Brien. (2006) Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time. Life Sciences 79:1, pages 21-29.
Crossref
Crossref
Wim P.D. Lemahieu, Bart D. Maes, Kristin Verbeke & Yves Vanrenterghem. (2005) Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: Consequences for FK506 assimilation. Kidney International 67:3, pages 1152-1160.
Crossref
Crossref
Annalise Di Marco, Dan Yao & Ralph Laufer. (2003) Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes. European Journal of Biochemistry 270:18, pages 3768-3777.
Crossref
Crossref
Majid Y Moridani, Sophia S Cheon, Sumsullah Khan & Peter J O'Brien. (2003) Metabolic activation of 3-hydroxyanisole by isolated rat hepatocytes. Chemico-Biological Interactions 142:3, pages 317-333.
Crossref
Crossref
M. Y. Moridani, S. S. Cheon, S. Khan & P. J. O'Brien. (2002) Metabolic Activation of 4-Hydroxyanisole by Isolated Rat Hepatocytes. Drug Metabolism and Disposition 30:10, pages 1063-1069.
Crossref
Crossref
Toshiro Niwa, Akira Kageyama, Kae Kishimoto, Yoshiyasu Yabusaki, Fumihide Ishibashi & Masanao Katagiri. (2002) Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19. Drug Metabolism and Disposition 30:8, pages 931-936.
Crossref
Crossref
Florence Grand, Izzet Kilinc, Albert Sarkis & Jérôme Guitton. (2002) Application of Isotopic Ratio Mass Spectrometry for the in Vitro Determination of Demethylation Activity in Human Liver Microsomes Using N-methyl-13C-Labeled Substrates. Analytical Biochemistry 306:2, pages 181-187.
Crossref
Crossref
Jian Zhu-Ge. (2002)
Establishment of a transgenic cell line stably expressing human cytochrome P450 2C18 and identification of a
CYP2C18
clone with exon 5 missing
. World Journal of Gastroenterology 8:5, pages 888.
Crossref
Crossref
Toshiro Niwa, Yumi Maekawa, Megumi Fujimoto, Kae KishimotoYoshiyasu YabusakiFumihide Ishibashi & Masanao Katagiri. (2002) Inhibition of Human Hepatic Cytochrome P450s and Steroidogenic CYP17 by Nonylphenol.. Biological and Pharmaceutical Bulletin 25:2, pages 235-238.
Crossref
Crossref
Samuel Achilefu & Richard B. Dorshow. 2002. Contrast Agents II. Contrast Agents II
31
72
.
Toshiro NIWA, Megumi FUJIMOTO, Kae KISHIMOTOYoshiyasu YABUSAKIFumihide ISHIBASHI & Masanao KATAGIRI. (2001) Metabolism and Interaction of Bisphenol A in Human Hepatic Cytochrome P450 and Steroidogenic CYP17.. Biological and Pharmaceutical Bulletin 24:9, pages 1064-1067.
Crossref
Crossref