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Obstetrics

Intravaginal use of natural micronised progesterone to prevent pre-term birth: A randomised trial in India

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Pages 493-498 | Published online: 06 Apr 2010

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J. Phung, K.P. Williams, L. McAullife, W.N. Martin, C. Flint, B. Andrew, J. Hyett, F. Park & C.E. Pennell. (2022) Vaginal progesterone for prevention of preterm birth in asymptomatic high-risk women with a normal cervical length: a systematic review and meta-analysis. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 7093-7101.
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Shruti Shambhavi, Rashmi Bagga, Pallavi Bansal, Jasvinder Kalra & Praveen Kumar. (2018) A randomised trial to compare 200 mg micronised progesterone effervescent vaginal tablet daily with 250 mg intramuscular 17 alpha hydroxy progesterone caproate weekly for prevention of recurrent preterm birth. Journal of Obstetrics and Gynaecology 38:6, pages 800-806.
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Articles from other publishers (30)

Ulla-Britt Wennerholm, Lina Bergman, Pihla Kuusela, Elin Ljungström, Anna C. Möller, Cecilie Hongslo Vala, Ann-Catrin Ekelund, Ann Liljegren, Max Petzold, Petteri Sjögren, Mikael Svensson, Annika Strandell & Bo Jacobsson. (2023) Progesterone, cerclage, pessary, or acetylsalicylic acid for prevention of preterm birth in singleton and multifetal pregnancies – A systematic review and meta-analyses. Frontiers in Medicine 10.
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Agustin Conde-Agudelo & Roberto Romero. (2023) Vaginal progesterone for the prevention of preterm birth: who can benefit and who cannot? Evidence-based recommendations for clinical use. Journal of Perinatal Medicine 51:1, pages 125-134.
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Agustin Conde-Agudelo & Roberto Romero. (2022) Does vaginal progesterone prevent recurrent preterm birth in women with a singleton gestation and a history of spontaneous preterm birth? Evidence from a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology 227:3, pages 440-461.e2.
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Lesley A Stewart, Mark Simmonds, Lelia Duley, Alexis Llewellyn, Sahar Sharif, Ruth AE Walker, Lucy Beresford, Kath Wright, Mona M Aboulghar, Zarko Alfirevic, Azam Azargoon, Rashmi Bagga, Elham Bahrami, Sean C Blackwell, Steve N Caritis, C Andrew Combs, Jennifer M Croswell, Caroline A Crowther, Anita F Das, Kay Dickersin, Kristina C Dietz, Andrew Elimian, William A Grobman, Alexander Hodkinson, Kimberley A Maurel, David S McKenna, Ben W Mol, Kelle Moley, Jamie Mueller, Anwar Nassar, Jane E Norman, John Norrie, John M O'Brien, Raphael Porcher, Shalini Rajaram, Line Rode, Dwight J Rouse, Carol Sakala, Ewoud Schuit, Marie-Victoire Senat, Sahar Sharif, Mark Simmonds, Joe L Simpson, Katherine Smith, Anne Tabor, Elizabeth A Thom, Melanie A van Os, Evelyn P Whitlock, Stephen Wood & Tom Walley. (2021) Evaluating Progestogens for Preventing Preterm birth International Collaborative (EPPPIC): meta-analysis of individual participant data from randomised controlled trials. The Lancet 397:10280, pages 1183-1194.
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S‐J Choi, DW Kwak, K Kil, S‐C Kim, J‐Y Kwon, YH Kim, S Na, J‐G Bae, H‐H Cha, J‐Y Shim, KY Oh, KA Lee, SM Kim, IA Cho, SM Lee, GJ Cho, YS Jo, GY Choi, SK Choi, SE Hur, HS Hwang & YJ Kim. (2020) Vaginal compared with intramuscular progestogen for preventing preterm birth in high‐risk pregnant women (VICTORIA study): a multicentre, open‐label randomised trial and meta‐analysis. BJOG: An International Journal of Obstetrics & Gynaecology 127:13, pages 1646-1654.
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A Jarde, O Lutsiv, J Beyene & SD McDonald. (2019) Vaginal progesterone, oral progesterone, 17-OHPC, cerclage, and pessary for preventing preterm birth in at-risk singleton pregnancies: an updated systematic review and network meta-analysis. BJOG: An International Journal of Obstetrics & Gynaecology 126:5, pages 556-567.
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Bridget Martell, Dana B. DiBenedetti, Herman Weiss, Xiaolei Zhou, Maria Reynolds, Vincenzo Berghella & Sonia S. Hassan. (2017) Screening and treatment for short cervical length in pregnancy: a physician survey in the United States. Archives of Gynecology and Obstetrics 297:3, pages 601-611.
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Roberto Romero, Agustin Conde-Agudelo, Eduardo Da Fonseca, John M. O’Brien, Elcin Cetingoz, George W. Creasy, Sonia S. Hassan & Kypros H. Nicolaides. (2018) Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data. American Journal of Obstetrics and Gynecology 218:2, pages 161-180.
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Caroline A. Crowther, Pat Ashwood, Andrew J. McPhee, Vicki Flenady, Thach Tran, Jodie M. Dodd & Jeffrey S. Robinson. (2017) Vaginal progesterone pessaries for pregnant women with a previous preterm birth to prevent neonatal respiratory distress syndrome (the PROGRESS Study): A multicentre, randomised, placebo-controlled trial. PLOS Medicine 14:9, pages e1002390.
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A Jarde, O Lutsiv, CK Park, J Beyene, JM Dodd, J Barrett, PS Shah, JL Cook, S Saito, AB Biringer, L Sabatino, L Giglia, Z Han, K Staub, W Mundle, J Chamberlain & SD McDonald. (2017) Effectiveness of progesterone, cerclage and pessary for preventing preterm birth in singleton pregnancies: a systematic review and network meta-analysis. BJOG: An International Journal of Obstetrics & Gynaecology 124:8, pages 1176-1189.
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Suk-Joo Choi. (2017) Use of progesterone supplement therapy for prevention of preterm birth: review of literatures. Obstetrics & Gynecology Science 60:5, pages 405.
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Kaitlin Siou, Sharon L. Walmsley, Kellie E. Murphy, Janet Raboud, Mona Loutfy, Mark H. Yudin, Michael Silverman, Noor N. Ladhani & Lena Serghides. (2016) Progesterone supplementation for HIV-positive pregnant women on protease inhibitor-based antiretroviral regimens (the ProSPAR study): a study protocol for a pilot randomized controlled trial. Pilot and Feasibility Studies 2:1.
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E. Azria. (2016) Intérêt des progestatifs dans la prévention de la prématurité spontanée. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 45:10, pages 1280-1298.
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R. Romero, K. H. Nicolaides, A. Conde‐Agudelo, J. M. O'Brien, E. Cetingoz, E. Da Fonseca, G. W. Creasy & S. S. Hassan. (2016) Vaginal progesterone decreases preterm birth ≤ 34 weeks of gestation in women with a singleton pregnancy and a short cervix: an updated meta‐analysis including data from the OPPTIMUM study . Ultrasound in Obstetrics & Gynecology 48:3, pages 308-317.
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Young Ju Kim. (2016) Progesterone treatment for the prevention of preterm birth. Journal of the Korean Medical Association 59:4, pages 319.
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Hyun-Joo SeolSuk Joo ChoiSoo-young Oh. (2016) Progesterone Treatment for Prevention of Preterm Birth. Perinatology 27:4, pages 205.
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Anju Suhag, Gabriele Saccone & Vincenzo Berghella. (2015) Vaginal progesterone for maintenance tocolysis: a systematic review and metaanalysis of randomized trials. American Journal of Obstetrics and Gynecology 213:4, pages 479-487.
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Sabine Zoghbi Bousleiman, Madeline Murguia Rice, Joan Moss, Allison Todd, Monica Rincon, Gail Mallett, Cynthia Milluzzi, Donna Allard, Karen Dorman, Felecia Ortiz, Francee Johnson, Peggy Reed, Susan Tolivaisa, R. Wapner, C. Ananth, L. Plante, M. Hoffman, S. Lort, A. Ranzini, G. Saade, M. Costantine, J. Brandon, G. Hankins, A. Salazar, A. Tita, W. Andrews, J.E. Tolosa, A. Lawrence, C. Clock, M. Blaser, M. Nichols, L. Pereira, A. Peaceman, M. Dinsmoor, J. Senka, K. Paychek, B. Mercer, J. Bailit, D. Rouse, B. Anderson, J. Tillinghast, M. Jimenez, S. Timlin, S. Blackwell, J. Iams, M. Varner, K. Hill, V. Morby, G. Anderson, E. Thom, L. Doherty, C. Swartz, B. Broderick, P. McGee, Y. Zhao, T. Spangler, G. Sandoval, C. Spong & J.P. Van Dorsten. (2015) Use and attitudes of obstetricians toward 3 high-risk interventions in MFMU Network hospitals. American Journal of Obstetrics and Gynecology 213:3, pages 398.e1-398.e11.
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Gabriele Saccone, Anju Suhag & Vincenzo Berghella. (2015) 17-alpha-hydroxyprogesterone caproate for maintenance tocolysis: a systematic review and metaanalysis of randomized trials. American Journal of Obstetrics and Gynecology 213:1, pages 16-22.
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Mona Aboulghar & Yomna Islam. (2013) Twin and Preterm Labor: Prediction and Treatment. Current Obstetrics and Gynecology Reports 2:4, pages 232-239.
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Jodie M Dodd, Leanne Jones, Vicki Flenady, Robert Cincotta & Caroline A Crowther. (2013) Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth. Cochrane Database of Systematic Reviews.
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Digna R. Velez Edwards, Frances E. Likis, Jeffrey C. Andrews, Alison L. Woodworth, Rebecca N. Jerome, Christopher J. Fonnesbeck, J. Nikki McKoy & Katherine E. Hartmann. (2013) Progestogens for preterm birth prevention: a systematic review and meta-analysis by drug route. Archives of Gynecology and Obstetrics 287:6, pages 1059-1066.
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Agustin Conde-Agudelo, Roberto Romero, Kypros Nicolaides, Tinnakorn Chaiworapongsa, John M. O'Brien, Elcin Cetingoz, Eduardo da Fonseca, George Creasy, Priya Soma-Pillay, Shalini Fusey, Cetin Cam, Zarko Alfirevic & Sonia S. Hassan. (2013) Vaginal progesterone vs cervical cerclage for the prevention of preterm birth in women with a sonographic short cervix, previous preterm birth, and singleton gestation: a systematic review and indirect comparison metaanalysis. American Journal of Obstetrics and Gynecology 208:1, pages 42.e1-42.e18.
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Frances E. Likis, Digna R. Velez Edwards, Jeffrey C. Andrews, Alison L. Woodworth, Rebecca N. Jerome, Christopher J. Fonnesbeck, J. Nikki McKoy & Katherine E. Hartmann. (2012) Progestogens for Preterm Birth Prevention. Obstetrics & Gynecology 120:4, pages 897-907.
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Tülay Özlü, Ayşenur Çakır Güngör, Melahat Emine Dönmez & Bülent Duran. (2012) Use of progestogens in pregnant and infertile patients. Archives of Gynecology and Obstetrics 286:2, pages 495-503.
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Carla E. Ransom & Amy P. Murtha. (2012) Progesterone for Preterm Birth Prevention. Obstetrics and Gynecology Clinics of North America 39:1, pages 1-16.
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Roberto Romero, Kypros Nicolaides, Agustin Conde-Agudelo, Ann Tabor, John M. O'Brien, Elcin Cetingoz, Eduardo Da Fonseca, George W. Creasy, Katharina Klein, Line Rode, Priya Soma-Pillay, Shalini Fusey, Cetin Cam, Zarko Alfirevic & Sonia S. Hassan. (2012) Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data. American Journal of Obstetrics and Gynecology 206:2, pages 124.e1-124.e19.
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Lindsay Ji Hyun SeongMin Ji KimYeri LeeSo-Yeon YoonHyun-Hwa ChaHye-Min KwakSuk-Joo ChoiSoo-young OhCheong-Rae RohJong-Hwa Kim. (2012) Vaginal micronized natural progesterone treatment and reduced risk of recurrent preterm birth. Korean Journal of Obstetrics & Gynecology 55:10, pages 699.
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