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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 40, 2018 - Issue 1
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Original Research Paper

Edaravone attenuates oxidative stress induced by chronic cerebral hypoperfusion injury: role of ERK/Nrf2/HO-1 signaling pathway

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Pages 1-10 | Received 05 Feb 2017, Accepted 01 Sep 2017, Published online: 10 Nov 2017

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Seyyedeh-Mahla Shavakandi, Mina Ranjbaran, Fatemeh Nabavizadeh, Reyhaneh Vali, Fardin Sehati & Ghorbangol Ashabi. (2022) Dimethyl fumarate protects the aged brain following chronic cerebral hypoperfusion-related ischemia in rats in Nrf2-dependent manner. Nutritional Neuroscience 25:10, pages 2100-2110.
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Natsumi Koike, Ayaka Sasaki, Tomoaki Murakami & Kazuhiko Suzuki. (2021) Effect of edaravone against cisplatin-induced chronic renal injury. Drug and Chemical Toxicology 44:4, pages 437-446.
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Danuta Jantas, Piotr Warszyński & Władysław Lasoń. (2023) Carnosic Acid Shows Higher Neuroprotective Efficiency than Edaravone or Ebselen in In Vitro Models of Neuronal Cell Damage. Molecules 29:1, pages 119.
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Peijie Fu, Yanghang Chen, Moxin Wu, Bing Bao, Xiaoping Yin, Zhiying Chen & Manqing Zhang. (2023) Effect of ferroptosis on chronic cerebral hypoperfusion in vascular dementia. Experimental Neurology 370, pages 114538.
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Yangyue Cao, Xuanye Yue, Meng Jia & Jiawei Wang. (2023) Neuroinflammation and anti-inflammatory therapy for ischemic stroke. Heliyon 9:7, pages e17986.
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Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu & Ruiqin Yao. (2023) Ebselen alleviates white matter lesions and improves cognitive deficits by attenuating oxidative stress via Keap1/Nrf2 pathway in chronic cerebral hypoperfusion mice. Behavioural Brain Research 448, pages 114444.
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Wael Mohamed. 2023. Trace Elements in Brain Health and Diseases. Trace Elements in Brain Health and Diseases 115 139 .
Wen Zhang, Haiguang Yang, Mei Gao, Hengai Zhang, Lili Shi, Xiaoyan Yu, Rui Zhao, Junke Song & Guanhua Du. (2022) Edaravone Dexborneol Alleviates Cerebral Ischemic Injury via MKP-1-Mediated Inhibition of MAPKs and Activation of Nrf2. BioMed Research International 2022, pages 1-12.
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Daniela Impellizzeri, Ramona D’Amico, Roberta Fusco, Tiziana Genovese, Alessio Filippo Peritore, Enrico Gugliandolo, Rosalia Crupi, Livia Interdonato, Davide Di Paola, Rosanna Di Paola, Salvatore Cuzzocrea, Rosalba Siracusa & Marika Cordaro. (2022) Açai Berry Mitigates Vascular Dementia-Induced Neuropathological Alterations Modulating Nrf-2/Beclin1 Pathways. Cells 11:16, pages 2616.
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Jingyang Le, Xiao Xiao, Difan Zhang, Yi Feng, Zhuoying Wu, Yuechun Mao, Chenye Mou, Yanfei Xie, Xiaowei Chen, Hao Liu & Wei Cui. (2022) Neuroprotective Effects of an Edible Pigment Brilliant Blue FCF against Behavioral Abnormity in MCAO Rats. Pharmaceuticals 15:8, pages 1018.
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Aki Soejima-Kusunoki, Kinya Okada, Ryuta Saito & Kazuhiko Watabe. (2022) The Protective Effect of Edaravone on TDP-43 Plus Oxidative Stress-Induced Neurotoxicity in Neuronal Cells: Analysis of Its Neuroprotective Mechanisms Using RNA Sequencing. Pharmaceuticals 15:7, pages 842.
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D MICHALIČKOVÁ, H KÜBRA ÖZTÜRK, J HROUDOVÁ, M ĽUPTÁK, T KUČERA, T HRNČÍŘ, N KUTINOVÁ CANOVÁ, M ŠÍMA & O SLANAŘ. (2022) Edaravone Attenuates Disease Severity of Experimental Auto-Immune Encephalomyelitis and Increases Gene Expression of Nrf2 and HO-1. Physiological Research, pages 147-157.
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Pedro Henrique Villar-Delfino, Nathália Augusta Oliveira Gomes, Paulo Pereira Christo, José Augusto Nogueira-Machado & Caroline Maria Oliveira Volpe. (2022) Edaravone Inhibits the Production of Reactive Oxygen Species in Phagocytosis- and PKC-Stimulated Granulocytes from Multiple Sclerosis Patients Edaravone Modulate Oxidative Stress in Multiple Sclerosis. Journal of Central Nervous System Disease 14, pages 117957352210925.
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Xi Gong, Jing Cheng, Kunshan Zhang, Yanlu Wang, Siguang Li & Yuping Luo. (2022) Transcriptome sequencing reveals Gastrodia elata Blume could increase the cell viability of eNPCs under hypoxic condition by improving DNA damage repair ability. Journal of Ethnopharmacology 282, pages 114646.
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Mohammad A.Y. Alqudah, Akram Al-Nosairy, Karem H. Alzoubi, Omar F. Kahbour & Sayer I. Alazzam. (2022) Edaravone prevents memory impairment in diabetic rats: Role of oxidative stress. Informatics in Medicine Unlocked 33, pages 101096.
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Emad H. M. Hassanein, Marwa A. Ahmed, Ahmed M. Sayed, Eman K. Rashwan, Omnia A. M. Abd El‐Ghafar & Ayman M. Mahmoud. (2021) Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR‐4/NF‐κB, and JAK1/STAT3 signaling in cyclophosphamide‐intoxicated rats. Journal of Biochemical and Molecular Toxicology 35:11.
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