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Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4‐aminobiphenyl in human and rat liver microsomes

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Pages 46-52 | Received 03 Aug 1998, Accepted 16 Nov 1998, Published online: 04 Aug 2009

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Rosa Busquets, Henrik Frandsen, Jan Åke Jönsson, Lluís Puignou, Maria Teresa Galceran & Kerstin Skog. (2013) Biomonitoring of Dietary Heterocyclic Amines and Metabolites in Urine by Liquid Phase Microextraction: 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine (PhIP), a Possible Biomarker of Exposure to Dietary PhIP . Chemical Research in Toxicology 26:2, pages 233-240.
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Sabine Rohrmann, Silke Hermann & Jakob Linseisen. (2009) Heterocyclic aromatic amine intake increases colorectal adenoma risk: findings from a prospective European cohort study. The American Journal of Clinical Nutrition 89:5, pages 1418-1424.
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Christopher D. Mann, Christopher P. Neal, Giuseppe Garcea, Margaret M. Manson, Ashley R. Dennison & David P. Berry. (2009) Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis. European Journal of Cancer Prevention 18:1, pages 13-25.
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Kai-Shan Tao, Wen Wang, Ling Wang, Da-Yong Cao, Yong-Qi Li, Sheng-Xi Wu & Ke-Feng Dou. (2008) The multifaceted mechanisms for coffee’s anti-tumorigenic effect on liver. Medical Hypotheses 71:5, pages 730-736.
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Hau Yi Leung, Yun Wang, Ho Yee Chan & Lai K. Leung. (2007) Developing a high-throughput system for the screening of cytochrome P450 1A1 – Inhibitory polyphenols. Toxicology in Vitro 21:6, pages 996-1002.
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S. Knasmüller, C. Hölzl, J. Bichler, A. Nersesyan & V.A. Ehrlich. 2006. Acrylamide and Other Hazardous Compounds in Heat-Treated Foods. Acrylamide and Other Hazardous Compounds in Heat-Treated Foods 425 458 .
B.J. Majer, E. Hofer, C. Cavin, E. Lhoste, M. Uhl, H.R. Glatt, W. Meinl & S. Knasmüller. (2005) Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2). Food and Chemical Toxicology 43:3, pages 433-441.
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L.T. Wu, C.C. Chu, J.G. Chung, C.-H. Chen, L.-S. Hsu, J.-K. Liu & S.C. Chen. (2004) Effects of tannic acid and its related compounds on food mutagens or hydrogen peroxide-induced DNA strands breaks in human lymphocytes. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 556:1-2, pages 75-82.
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Sidhartha Ray & Debasis Bagchi. 2004. Phytopharmaceuticals in Cancer Chemoprevention. Phytopharmaceuticals in Cancer Chemoprevention.
James Bacon & Yongping Bao. 2004. Phytochemicals in Health and Disease. Phytochemicals in Health and Disease 143 162 .
Susanne N. Williams, George V. Pickwell & Linda C. Quattrochi. (2003) A Combination of Tea (Camellia senensis) Catechins Is Required for Optimal Inhibition of Induced CYP1A Expression by Green Tea Extract . Journal of Agricultural and Food Chemistry 51:22, pages 6627-6634.
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Radoslav Goldman & Peter G. Shields. (2003) Food Mutagens. The Journal of Nutrition 133:3, pages 965S-973S.
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Tao-Tao Liu. (2003) Effects of long-term tea polyphenols consumption on hepatic microsomal drug-metabolizing enzymes and liver function in Wistar rats. World Journal of Gastroenterology 9:12, pages 2742.
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Fu-Li Yu, Wanda Bender, Qingming Fang, Anna Ludeke & Brianna Welch. (2003) Prevention of chemical carcinogen DNA binding and inhibition of nuclear RNA polymerase activity by organosulfur compounds as the possible mechanisms for their anticancer initiation and proliferation effects. Cancer Detection and Prevention 27:5, pages 370-379.
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H. Vainio & E. Hietanen. 2003. Mechanisms in Carcinogenesis and Cancer Prevention. Mechanisms in Carcinogenesis and Cancer Prevention 1 11 .
Bent H Havsteen. (2002) The biochemistry and medical significance of the flavonoids. Pharmacology & Therapeutics 96:2-3, pages 67-202.
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C Cavin, D Holzhaeuser, G Scharf, A Constable, W.W Huber & B Schilter. (2002) Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity. Food and Chemical Toxicology 40:8, pages 1155-1163.
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Hyung-Chul Lee, Sang-Gu Hwang, Young-Gu Lee, Hyung-Ok Sohn, Dong-Wook Lee, Seok-Youn Hwang, Yi-Swong Kwak, Jae-Joon Wee, Woo-Hong Joo, Yong-Kweon Cho & Ja-Young Moon. (2002) In vivo effects of Panax ginseng extracts on the cytochrome P450-dependent monooxygenase system in the liver of 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed guinea pig. Life Sciences 71:7, pages 759-769.
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C Cavin, K Mace, E.A Offord & B Schilter. (2001) Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells. Food and Chemical Toxicology 39:6, pages 549-556.
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I.P. Grudzinski, A. Frankiewicz-Jozko & J. Bany. (2001) Diallyl sulfide – a flavour component from garlic (Allium sativum) attenuates lipid peroxidation in mice infected with Trichinella spiralis. Phytomedicine 8:3, pages 174-177.
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Susanne N Williams, Hsueh Shih, Denis K Guenette, William Brackney, Michael S Denison, George V Pickwell & Linda C Quattrochi. (2000) Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression. Chemico-Biological Interactions 128:3, pages 211-229.
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