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Research Article

Formulation of rate-modulating pellets for the release of ibuprofen: An extrusion–spheronization process

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Pages 643-659 | Received 08 Nov 2004, Accepted 20 Apr 2005, Published online: 03 Oct 2008

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M. C. Hamoudi, J. Saunier, C. Gueutin, E. Fattal & A. Bochot. (2013) Beads made of α-cyclodextrin and soybean oil: the drying method influences bead properties and drug release. Drug Development and Industrial Pharmacy 39:9, pages 1306-1314.
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Hardik Rana, Vaishali Thakkar, Kalpana Mudgal, Mukesh Gohel, Lalji Baldania, Mansi Dholakia & Tejal Gandhi. (2019) Systematic Scrutinisation of Vital Factors for Fabrication and Evaluation of PGS-MCC Based Drug Loaded Pellets by Extrusion Spheronization Technique. Current Drug Therapy 14:2, pages 168-182.
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Thanh Huong Hoang Thi, Siham Lhafidi, Simone Pinto Carneiro & Marie-Pierre Flament. (2015) Feasability of a new process to produce fast disintegrating pellets as novel multiparticulate dosage form for pediatric use. International Journal of Pharmaceutics 496:2, pages 842-849.
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S. Schrank, B. Kann, E. Saurugger, M. Hainschitz, M. Windbergs, B.J. Glasser, J. Khinast & E. Roblegg. (2015) The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: Pellet microstructure, drug distribution, solid state and drug dissolution. International Journal of Pharmaceutics 478:2, pages 779-787.
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Simone Schrank, Birthe Kann, Maike Windbergs, Benjamin J. Glasser, Andreas Zimmer, Johannes Khinast & Eva Roblegg. (2013) Microstructure of Calcium Stearate Matrix Pellets: A Function of the Drying Process. Journal of Pharmaceutical Sciences 102:11, pages 3987-3997.
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Simone Schrank, Aden Hodzic, Andreas Zimmer, Benjamin J. Glasser, Johannes Khinast & Eva Roblegg. (2012) Ibuprofen-Loaded Calcium Stearate Pellets: Drying-Induced Variations in Dosage Form Properties. AAPS PharmSciTech 13:2, pages 686-698.
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F.J. Otero-Espinar, A. Luzardo-Alvarez & J. Blanco-Méndez. (2010) Non-MCC materials as extrusion-spheronization aids in pellets production. Journal of Drug Delivery Science and Technology 20:4, pages 303-318.
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