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Original

Oral delivery of low molecular weight heparin microspheres prepared using biodegradable polymer matrix system

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Pages 493-500 | Received 11 Aug 2008, Accepted 09 Sep 2008, Published online: 21 Aug 2009

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Shaimaa S. Ibrahim, Rihab Osman, Nahed D. Mortada, Ahmed-Shawky Geneidy & Gehanne A. S. Awad. (2017) Passive targeting and lung tolerability of enoxaparin microspheres for a sustained antithrombotic activity in rats. Drug Delivery 24:1, pages 243-251.
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Shaimaa S. Ibrahim, Rihab Osman, Gehanne A. S. Awad, Nahed D. Mortada & Ahmed-Shawky Geneidy. (2016) Low molecular weight heparins for current and future uses: approaches for micro- and nano-particulate delivery. Drug Delivery 23:8, pages 2661-2667.
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Mohammad Nasir Uddin, Neil J. Patel, Tuhin Bhowmik, Bernadette D’Souza, Archana Akalkotkar, Frank Etzlar, Carl William Oettinger & Martin D’Souza. (2013) Enhanced bioavailability of orally administered antisense oligonucleotide to nuclear factor kappa B mRNA after microencapsulation with albumin. Journal of Drug Targeting 21:5, pages 450-457.
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Canan İskenderoğlu, Füsun Acartürk, Deniz Erdoğan & Yeşim Bardakçı. (2013) In vitro and in vivo investigation of low molecular weight heparin–alginate beads for oral administration. Journal of Drug Targeting 21:4, pages 389-406.
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José Martínez-González & Cristina Rodríguez. (2010) New challenges for a second-generation low-molecular-weight heparin: focus on bemiparin. Expert Review of Cardiovascular Therapy 8:5, pages 625-634.
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Mousumi Tudu & Amalesh Samanta. (2023) Natural polysaccharides: Chemical properties and application in pharmaceutical formulations. European Polymer Journal 184, pages 111801.
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Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia & Xiang-hong Sun. (2019) Nanoparticles: Oral Delivery for Protein and Peptide Drugs. AAPS PharmSciTech 20:5.
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Wei Dong, Xiuhua Wang, Chang Liu, Xiao Zhang, Xin Zhang, Xianzhi Chen, Yongqiang Kou & Shirui Mao. (2018) Chitosan based polymer-lipid hybrid nanoparticles for oral delivery of enoxaparin. International Journal of Pharmaceutics 547:1-2, pages 499-505.
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Fahad Akhtar, Xinyu Wan, Gang Wu, Samuel Kesse, Shaoda Wang & Shuying He. (2018) Low-Molecular-Weight Heparins: Reduced Size Particulate Systems for Improved Therapeutic Outcomes. Molecules 23:7, pages 1757.
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Hailong Zhang, Jie Mi, Yayu Huo, Xiaoyan Huang, Jianfeng Xing, Akira Yamamoto & Yang Gao. (2014) Absorption enhancing effects of chitosan oligomers on the intestinal absorption of low molecular weight heparin in rats. International Journal of Pharmaceutics 466:1-2, pages 156-162.
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Joshua J. Reineke, Daniel Y. Cho, Yu-Ting Dingle, A. Peter MorelloIIIIII, Jules Jacob, Christopher G. Thanos & Edith Mathiowitz. (2013) Unique insights into the intestinal absorption, transit, and subsequent biodistribution of polymer-derived microspheres. Proceedings of the National Academy of Sciences 110:34, pages 13803-13808.
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Ralf Schwörer, Olga V. Zubkova, Jeremy E. Turnbull & Peter C. Tyler. (2013) Synthesis of a Targeted Library of Heparan Sulfate Hexa‐ to Dodecasaccharides as Inhibitors of β‐Secretase: Potential Therapeutics for Alzheimer’s Disease. Chemistry – A European Journal 19:21, pages 6817-6823.
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Rishi Paliwal, Shivani R. Paliwal, Govind P. Agrawal & Suresh P. Vyas. (2011) Recent advances in search of oral heparin therapeutics. Medicinal Research Reviews 32:2, pages 388-409.
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Rishi Paliwal, Shivani R. Paliwal, Govind P. Agrawal & Suresh P. Vyas. (2012) Chitosan nanoconstructs for improved oral delivery of low molecular weight heparin: In vitro and in vivo evaluation. International Journal of Pharmaceutics 422:1-2, pages 179-184.
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Rishi Paliwal, Shivani R. Paliwal, Govind P. Agrawal & Suresh P. Vyas. (2011) Biomimetic Solid Lipid Nanoparticles for Oral Bioavailability Enhancement of Low Molecular Weight Heparin and Its Lipid Conjugates: In Vitro and in Vivo Evaluation . Molecular Pharmaceutics 8:4, pages 1314-1321.
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HAIRUI LI, JASPREET SINGH KOCHHAR, JING PAN, SUI YUNG CHAN & LIFENG KANG. (2011) NANO/MICROSCALE TECHNOLOGIES FOR DRUG DELIVERY. Journal of Mechanics in Medicine and Biology 11:02, pages 337-367.
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