Advanced search
Publication Cover
Journal of Microencapsulation
Micro and Nano Carriers
Volume 26, 2009 - Issue 6
Submit an article Journal homepage
125
Views
17
CrossRef citations to date
0
Altmetric
Original

The intestinal permeation of didanosine from granules containing microspheres using the everted gut sac model

Classius Ferreira da Silva Biotechnological Processes Development Laboratory, School of Chemical Engineering, State University of Campinas-UNICAMP, Campinas, SP, Brazil; Science and Technology Center, State University of West of Parana-UNIOESTE, Toledo, PR, Brazil
,
Patrícia Severino Biotechnological Processes Development Laboratory, School of Chemical Engineering, State University of Campinas-UNICAMP, Campinas, SP, Brazil
,
Fernanda Martins Biotechnological Processes Development Laboratory, School of Chemical Engineering, State University of Campinas-UNICAMP, Campinas, SP, Brazil
,
Marco Vinicius Chaud School of Health Sciences, Methodist University of Piracicaba-UNIMEP, Piracicaba, SP, Brazil
&
Maria Helena Andrade Santana Biotechnological Processes Development Laboratory, School of Chemical Engineering, State University of Campinas-UNICAMP, Campinas, SP, BrazilCorrespondence[email protected]
Pages 523-528 | Received 18 Mar 2008, Accepted 10 Sep 2008, Published online: 25 Mar 2009

Citations (17)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Patricia Zancanella, Daniele M. L. Oliveira, Bonald H. de Oliveira, Thiago D. Woiski, Cesar C. Pinto, Maria H. A. Santana, Eliana B. Souto & Patrícia Severino. (2020) Mitotane liposomes for potential treatment of adrenal cortical carcinoma: ex vivo intestinal permeation and in vivo bioavailability. Pharmaceutical Development and Technology 25:8, pages 949-961.
Read now
Ana Raquel Madureira, Sara Nunes, Débora A Campos, João C Fernandes, Cláudia Marques, Monica Zuzarte, Beatriz Gullón, Luís M Rodríguez-Alcalá, Conceição Calhau, Bruno Sarmento, Ana Maria Gomes, Maria Manuela Pintado & Flávio Reis. (2016) Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches. International Journal of Nanomedicine 11, pages 3621-3640.
Read now
Patrícia Severino, Eliana B. Souto, Samantha C. Pinho & Maria H. A. Santana. (2013) Hydrophilic coating of mitotane-loaded lipid nanoparticles: Preliminary studies for mucosal adhesion. Pharmaceutical Development and Technology 18:3, pages 577-581.
Read now

Articles from other publishers (14)

Shashank Chaturvedi, Anuj Garg & Anurag Verma. (2020) Nano lipid based carriers for lymphatic voyage of anti-cancer drugs: An insight into the in-vitro, ex-vivo, in-situ and in-vivo study models. Journal of Drug Delivery Science and Technology 59, pages 101899.
Crossref
Nathaniel J. Clark, Waldemar Woznica & Richard D. Handy. (2020) Dietary bioaccumulation potential of silver nanomaterials compared to silver nitrate in wistar rats using an ex vivo gut sac technique. Ecotoxicology and Environmental Safety 200, pages 110745.
Crossref
Cynthia R. A. Mahl, Thiago B. Taketa, J. B. M. Rocha-Neto, Wanda P. Almeida & Marisa M. Beppu. (2019) Copper Ion Uptake by Chitosan in the Presence of Amyloid-β and Histidine. Applied Biochemistry and Biotechnology 190:3, pages 949-965.
Crossref
Ana Raquel Madureira, Débora A. Campos, Ana Oliveira, Bruno Sarmento, Maria Manuela Pintado & Ana Maria Gomes. (2016) Insights into the protective role of solid lipid nanoparticles on rosmarinic acid bioactivity during exposure to simulated gastrointestinal conditions. Colloids and Surfaces B: Biointerfaces 139, pages 277-284.
Crossref
Ana Raquel Madureira, Débora Campos, Beatriz Gullon, Cláudia Marques, Luís M. Rodríguez-Alcalá, Conceição Calhau, Jose Luis Alonso, Bruno Sarmento, Ana Maria Gomes & Manuela Pintado. (2016) Fermentation of bioactive solid lipid nanoparticles by human gut microflora. Food & Function 7:1, pages 516-529.
Crossref
Classius Ferreira da Silva, Patrícia Severino, Fernanda Martins, Maria Helena A. Santana & Eliana B. Souto. (2015) Didanosine-loaded chitosan microspheres optimized by surface-response methodology: A modified “Maximum Likelihood Classification” approach formulation for reverse transcriptase inhibitors. Biomedicine & Pharmacotherapy 70, pages 46-52.
Crossref
Katia P. Seremeta, Christian Höcht, Carlos Taira, Pablo R. Cortez Tornello, Gustavo A. Abraham & Alejandro Sosnik. (2015) Didanosine-loaded poly(epsilon-caprolactone) microparticles by a coaxial electrohydrodynamic atomization (CEHDA) technique. Journal of Materials Chemistry B 3:1, pages 102-111.
Crossref
Ana Raquel Madureira, Débora A. Campos, Pedro Fonte, Sara Nunes, Flávio Reis, Ana Maria Gomes, Bruno Sarmento & Maria Manuela Pintado. (2015) Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid oral delivery. RSC Advances 5:29, pages 22665-22673.
Crossref
Eliana B. Souto, Patrícia Severino, Rafael Basso & Maria Helena A. Santana. 2013. Oxidative Stress and Nanotechnology. Oxidative Stress and Nanotechnology 37 46 .
Patrícia Severino, Tatiana Andreani, Ana Sofia Macedo, Joana F. Fangueiro, Maria Helena A. Santana, Amélia M. Silva & Eliana B. Souto. (2012) Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. Journal of Drug Delivery 2012, pages 1-10.
Crossref
Patrícia Severino, George G.G. de Oliveira, Humberto G. Ferraz, Eliana B. Souto & Maria H.A. Santana. (2012) Preparation of gastro-resistant pellets containing chitosan microspheres for improvement of oral didanosine bioavailability. Journal of Pharmaceutical Analysis 2:3, pages 188-192.
Crossref
Priscileila C. Ferrari, Fagner M. Souza, Leandro Giorgetti, Giselle F. Oliveira, Marco V. Chaud, Humberto G. Ferraz & Raul C. Evangelista. (2012) In vitro drug permeation from chitosan pellets. Carbohydrate Polymers 87:4, pages 2526-2531.
Crossref
Mohd Aftab Alam, Fahad Ibrahim Al-Jenoobi & Abdullah M Al-mohizea. (2012) Everted gut sac model as a tool in pharmaceutical research: limitations and applications. Journal of Pharmacy and Pharmacology 64:3, pages 326-336.
Crossref
Patrícia Severino, Heloisa Silva, Eliana B. Souto, Maria Helena A. Santana & Teresa Cristina T. Dalla Costa. (2012) Analysis of in vivo absorption of didanosine tablets in male adult dogs by HPLC. Journal of Pharmaceutical Analysis 2:1, pages 29-34.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.