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Liquid Crystals Volume 48, 2021 - Issue 7
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Article

Improved skin-permeated diclofenac-loaded lyotropic liquid crystal nanoparticles: QbD-driven industrial feasible process and assessment of skin deposition

Tejashree WaghuleIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaORCID Iconhttps://orcid.org/0000-0002-6891-8999View further author information
ORCID Icon,
Shalini PatilIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaView further author information
,
Vamshi Krishna RapalliIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaORCID Iconhttps://orcid.org/0000-0002-6666-2029View further author information
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Vishal GirdharIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaView further author information
,
Srividya GorantlaIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaORCID Iconhttps://orcid.org/0000-0001-9722-3363View further author information
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Sunil Kumar DubeyIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaORCID Iconhttps://orcid.org/0000-0002-7554-3232View further author information
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Ranendra Narayan SahaIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaORCID Iconhttps://orcid.org/0000-0003-1177-3642View further author information
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Gautam SinghviIndustrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9706-9244View further author information
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Pages 991-1009 | Received 02 Jun 2020, Accepted 09 Oct 2020, Published online: 28 Oct 2020

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Tejashree Waghule, Ranendra Narayan Saha & Gautam Singhvi. (2023) Exploring microfluidics and membrane extrusion for the formulation of temozolomide-loaded liposomes: investigating the effect of formulation and process variables. Journal of Liposome Research 33:2, pages 170-182.
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Vamshi Krishna Rapalli, Arisha Mahmood, Tejashree Waghule, Srividya Gorantla, Sunil Kumar Dubey, Amit Alexander & Gautam Singhvi. (2021) Revisiting techniques to evaluate drug permeation through skin. Expert Opinion on Drug Delivery 18:12, pages 1829-1842.
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Articles from other publishers (13)

Mo. Suheb Ansari, Asad Ali, Md. Abdur Rashid, Yahya Alhamhoom, Niha Sultana, Ayesha Waheed, Md. Shabbir Alam, Mohd Aqil & Yasmin Sultana. (2024) BBD assisted in-situ nanoliposomes of esculin hydrate via intranasal delivery for the amelioration of Parkinson's disease. Journal of Drug Delivery Science and Technology 96, pages 105658.
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Shweta Nene, Ganesh Vambhurkar, Kamatham Pushpa Tryphena, Pankaj Kumar Singh, Dharmendra Kumar Khatri & Saurabh Srivastava. (2024) Evaluation of preclinical efficacy of apremilast-loaded liquid crystalline nanoparticulate gel in amelioration of atopic dermatitis. Journal of Drug Delivery Science and Technology 96, pages 105653.
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Chaitanya Shirke & Sarika Wairkar. (2024) Liquid Crystal Nanoparticles-based Fluocinolone Acetonide Topical Gel for Atopic Dermatitis: In vitro and in vivo Study. Journal of Pharmaceutical Innovation 19:3.
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Anam Ahsan, Nicky Thomas, Timothy J. Barnes, Santhni Subramaniam, Thou Chen Loh, Paul Joyce & Clive A. Prestidge. (2024) Lipid Nanocarriers-Enabled Delivery of Antibiotics and Antimicrobial Adjuvants to Overcome Bacterial Biofilms. Pharmaceutics 16:3, pages 396.
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S. Farid Mohseni-Motlagh, Roshanak Dolatabadi, Majid Baniassadi & Mostafa Baghani. (2023) Application of the Quality by Design Concept (QbD) in the Development of Hydrogel-Based Drug Delivery Systems. Polymers 15:22, pages 4407.
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Jassica S. L. Leu, Jasy J. X. Teoh, Angel L. Q. Ling, Joey Chong, Yan Shan Loo, Intan Diana Mat Azmi, Noor Idayu Zahid, Rajendran J. C. Bose & Thiagarajan Madheswaran. (2023) Recent Advances in the Development of Liquid Crystalline Nanoparticles as Drug Delivery Systems. Pharmaceutics 15:5, pages 1421.
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Austin Che, Carson O. Zellman, Diganta Sarkar, Simon Trudel-Lachance, Jayar Espejo, Vladimir K. Michaelis, Vance E. Williams & Chang-Chun Ling. (2023) Functional group polarity-modulated formation of liquid crystals of amphiphilic cyclodextrins. Journal of Materials Chemistry C 11:12, pages 4153-4163.
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Ana Vitoria Pupo Silvestrini, Bryan Wender Debiasi, Fabíola Garcia Praça & Maria Vitoria Lopes Badra Bentley. (2022) Progress and challenges of lyotropic liquid crystalline nanoparticles for innovative therapies. International Journal of Pharmaceutics 628, pages 122299.
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Ayesha Waheed, Saima Zameer, Niha Sultana, Asad Ali, Mohd. Aqil, Yasmin Sultana & Zeenat Iqbal. (2022) Engineering of QbD driven and ultrasonically shaped lyotropic liquid crystalline nanoparticles for Apigenin in the management of skin cancer. European Journal of Pharmaceutics and Biopharmaceutics 180, pages 269-280.
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Martine Tarsitano, Antonia Mancuso, Maria Chiara Cristiano, Donatella Paolino & Massimo Fresta. (2022) In Situ Swelling Formulation of Glycerol-Monooleate-Derived Lyotropic Liquid Crystals Proposed for Local Vaginal Application. Molecules 27:19, pages 6295.
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Arisha Mahmood, Vamshi Krishna Rapalli, Srividya Gorantla, Tejashree Waghule & Gautam Singhvi. (2021) Dermatokinetic assessment of luliconazole-loaded nanostructured lipid carriers (NLCs) for topical delivery: QbD-driven design, optimization, and in vitro and ex vivo evaluations. Drug Delivery and Translational Research 12:5, pages 1118-1135.
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Srividya Gorantla, Ranendra N. Saha & Gautam Singhvi. (2022) Exploring the affluent potential of glyceryl mono oleate – myristol liquid crystal nanoparticles mediated localized topical delivery of Tofacitinib: Study of systematic QbD, skin deposition and dermal pharmacokinetics assessment. Journal of Molecular Liquids 346, pages 117053.
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Vamshi Krishna Rapalli & Gautam Singhvi. (2020) Dermato-pharmacokinetic: assessment tools for topically applied dosage forms. Expert Opinion on Drug Delivery 18:4, pages 423-426.
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