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British Journal of Neurosurgery Volume 22, 2008 - Issue 4
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Original Article

Intrathecal baclofen therapy for neurological disorders: a sound knowledge base but many challenges remain

P. M. Brennan Department of Clinical Neurosciences, Western General Hospital, University of Edinburgh, UKCorrespondence[email protected]
&
I. R. Whittle Department of Clinical Neurosciences, Western General Hospital, University of Edinburgh, UK
Pages 508-519 | Received 15 Mar 2008, Accepted 28 May 2008, Published online: 06 Jul 2009

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Stina Gunnarsson & Kersti Samuelsson. (2015) Patient experiences with intrathecal baclofen as a treatment for spasticity – a pilot study. Disability and Rehabilitation 37:10, pages 834-841.
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Sung-Rae Cho. (2023) Intrathecal Baclofen Therapy: Pros and Cons. Annals of Rehabilitation Medicine 47:1, pages 1-3.
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Brian A. Duclos, Cindy Roegge, Howard Dobson, Scott Haller, Jeff Bodner, Sanjana Pannem, Janelle Gesaman & Amin Nourmohammadi. (2023) Cervical catheter placement leads to improved rostral distribution of a radiolabeled 18F-baclofen analog in cynomolgus monkeys. Translational Medicine Communications 8:1.
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Atul Vats, Amit Amit, Martin Cossar, Pragnesh Bhatt & Alastair Cozens. (2019) Intrathecal baclofen trial using a temporary indwelling intrathecal catheter – A single institution experience. Journal of Clinical Neuroscience 68, pages 33-38.
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Young Kwon Yoon, Kil Chan Lee, Han Eol Cho, Minji Chae, Jin Woo Chang, Won Seok Chang & Sung-Rae Cho. (2017) Outcomes of intrathecal baclofen therapy in patients with cerebral palsy and acquired brain injury. Medicine 96:34, pages e7472.
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B G Wallin, T Karlsson, G Pegenius, A-K Karlsson, V G Macefield & M Elam. (2014) Sympathetic single axonal discharge after spinal cord injury in humans: activity at rest and after bladder stimulation. Spinal Cord 52:6, pages 434-438.
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Francesco Motta & Clara E. Antonello. (2014) Analysis of complications in 430 consecutive pediatric patients treated with intrathecal baclofen therapy: 14-year experience. Journal of Neurosurgery: Pediatrics 13:3, pages 301-306.
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Roberto Carlo Rivera Díaz, Mario Andrés Arcila Lotero & Daniel Campuzano Escobar. (2013) Intrathecal baclofen for the treatment of spasticity. Case report with thematic review. Colombian Journal of Anesthesiology 41:3, pages 229-235.
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Roberto Carlo Rivera Díaz, Mario Andrés Arcila Lotero & Daniel Campuzano Escobar. (2013) Baclofeno intratecal para el tratamiento de la espasticidad. Reporte de caso con revisión temática. Revista Colombiana de Anestesiología 41:3, pages 229-235.
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Debabrata Ghosh, Gayatra Mainali, Jena Khera & Mark Luciano. (2013) Complications of Intrathecal Baclofen Pumps in Children: Experience from a Tertiary Care Center. Pediatric Neurosurgery 49:3, pages 138-144.
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Roberto Carlo Rivera Díaz, Mario Andrés Arcila Lotero & Daniel Campuzano Escobar. (2013) Intrathecal baclofen for the treatment of spasticity. Case report with thematic review☆. Colombian Journal of Anesthesiology 41:3, pages 229-235.
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Lisgelia Santana & Manuel Quintero. (2012) Management Baclofen Withdrawal Syndrome. Colombian Journal of Anesthesiology 40:2, pages 158-161.
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Lisgelia Santana & Manuel Quintero. (2012) Manejo del síndrome de abstinencia por interrupción del baclofeno. Revista Colombiana de Anestesiología 40:2, pages 158-161.
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Eduardo E. Benarroch. (2012) GABA B receptors . Neurology 78:8, pages 578-584.
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Lisgelia Santana & Manuel Quintero. (2012) Management Baclofen Withdrawal Syndrome. Colombian Journal of Anesthesiology 40:2, pages 158-161.
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A.C. Miracle, M.A. Fox, R.N. Ayyangar, A. Vyas, S.K. Mukherji & D.J. Quint. (2011) Imaging Evaluation of Intrathecal Baclofen Pump-Catheter Systems. American Journal of Neuroradiology 32:7, pages 1158-1164.
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Annelies Van Dycke, Robrecht Raedt, Kristl Vonck & Paul Boon. (2011) Local delivery strategies in epilepsy; a focus on adenosine. Seizure 20:5, pages 376-382.
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Hatice Kumru, Ivana Stetkarova, Christian Schindler, Joan Vidal & Markus Kofler. (2011) Neurophysiological evidence for muscle tone reduction by intrathecal baclofen at the brainstem level. Clinical Neurophysiology 122:6, pages 1229-1237.
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K Ramstad, R Jahnsen, B Lofterod & OH Skjeldal. (2009) Continuous intrathecal baclofen therapy in children with cerebral palsy – when does improvement emerge?. Acta Paediatrica 99:11, pages 1661-1665.
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A. Roubertie, E. Roze, N. Bahi-Buisson, C. Payet, B. Echenne & D. Doummar. (2010) Traitement des dystonies de l’enfant. Archives de Pédiatrie 17:5, pages 540-553.
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Joel S. Goldberg. (2010) Selected Gamma Aminobutyric Acid (GABA) Esters may Provide Analgesia for Some Central Pain Conditions. Perspectives in Medicinal Chemistry 4, pages PMC.S5490.
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Alexander H. HoonJr.Jr. & Andreia Vasconcellos Faria. (2011) Pathogenesis, neuroimaging and management in children with cerebral palsy born preterm. Developmental Disabilities Research Reviews 16:4, pages 302-312.
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N. Bresolin, C. Zucca & A. Pecori. (2009) Efficacy and tolerability of eperisone and baclofen in spastic palsy: a double-blind randomized trial. Advances in Therapy 26:5, pages 563-573.
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