Advanced search
Publication Cover
British Journal of Neurosurgery Volume 22, 2008 - Issue sup1: Proceedings from Pedunculopontine Nucleus Meeting
Submit an article Journal homepage
161
Views
63
CrossRef citations to date
0
Altmetric
Original Article

Stereotactic surgery of nucleus tegmenti pedunculopontini

P. Mazzone Functional and Stereotactic Neurosurgery, CTO, ASL RMC, Rome, ItalyCorrespondence[email protected]
,
S. Sposato Neuroradiology, CTO, ASL RMC, Rome, Italy
,
A. Insola Functional and Stereotactic Neurosurgery, CTO, ASL RMC, Rome, Italy
,
V. Dilazzaro Department of Neurosciences, Catholic University, Rome, Italy
&
E. Scarnati Department of Sciences and Biomedical Technologies, University of L'Aquila, Italy
Pages S33-S40 | Published online: 06 Jul 2009

Citations (63)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Lazzaro di Biase, Gerd Tinkhauser, Eduardo Martin Moraud, Maria Letizia Caminiti, Pasquale Maria Pecoraro & Vincenzo Di Lazzaro. (2021) Adaptive, personalized closed-loop therapy for Parkinson’s disease: biochemical, neurophysiological, and wearable sensing systems. Expert Review of Neurotherapeutics 21:12, pages 1371-1388.
Read now
Kaoru Takakusaki, Mirai Takahashi, Kazuhiro Obara & Ryosuke Chiba. (2017) Neural substrates involved in the control of posture. Advanced Robotics 31:1-2, pages 2-23.
Read now
Sadaquate Khan, Lucy Mooney, Puneet Plaha, Shazia Javed, Paul White, Alan L. Whone & Steven S. Gill. (2011) Outcomes from stimulation of the caudal zona incerta and pedunculopontine nucleus in patients with Parkinson's disease. British Journal of Neurosurgery 25:2, pages 273-280.
Read now

Articles from other publishers (60)

Alexander J. Baumgartner, John A. Thompson, Drew S. Kern & Steven G. Ojemann. (2022) Novel targets in deep brain stimulation for movement disorders. Neurosurgical Review 45:4, pages 2593-2613.
Crossref
Francisco J. Urbano & Edgar Garcia-Rill. 2022. Methodological Approaches for Sleep and Vigilance Research. Methodological Approaches for Sleep and Vigilance Research 101 110 .
Angelo Insola, Paolo Mazzone, Eugenio Scarnati, Domenico Restuccia & Massimiliano Valeriani. (2021) Contribution of different somatosensory afferent input to subcortical somatosensory evoked potentials in humans. Clinical Neurophysiology 132:10, pages 2357-2364.
Crossref
PareshK Doshi & Deepak Das. (2020) Deep Brain Stimulation for Parkinson's Disease: Currents Status and Emerging Concepts. Neurology India 68:8, pages 179.
Crossref
Lee Neilson, Jonathan Zande & Hesham Abboud. 2020. Diagnosis and Management in Parkinson's Disease. Diagnosis and Management in Parkinson's Disease 577 596 .
E. Garcia-Rill, S. Mahaffey, James R. Hyde & F.J. Urbano. (2019) Bottom-up gamma maintenance in various disorders. Neurobiology of Disease 128, pages 31-39.
Crossref
Edgar Garcia‐Rill. (2019) Neuroepigenetics of arousal: Gamma oscillations in the pedunculopontine nucleus. Journal of Neuroscience Research.
Crossref
Edgar Garcia-Rill, Alan Tackett, Stephanie Byrum, Renny Lan, Samuel Mackintosh, James Hyde, Veronica Bisagno & Francisco Urbano. (2019) Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus. Brain Sciences 9:3, pages 64.
Crossref
T. Virmani, F. J. Urbano, V. Bisagno & E. Garcia-Rill. (2019) The pedunculopontine nucleus: From posture and locomotion to neuroepigenetics. AIMS Neuroscience 6:4, pages 219-230.
Crossref
Edgar Garcia-Rill. 2019. Arousal in Neurological and Psychiatric Diseases. Arousal in Neurological and Psychiatric Diseases 179 193 .
A. T. D. L. Alho, C. Hamani, E. J. L. Alho, R. E. da Silva, G. A. B. Santos, R. C. Neves, L. L. Carreira, C. M. M. Araújo, G. Magalhães, D. B. Coelho, M. C. Alegro, M. G. M. Martin, L. T. Grinberg, C. A. Pasqualucci, H. Heinsen, E. T. Fonoff & E. AmaroJrJr. (2017) Magnetic resonance diffusion tensor imaging for the pedunculopontine nucleus: proof of concept and histological correlation. Brain Structure and Function 222:6, pages 2547-2558.
Crossref
Travis S. Tierney1 & Andres M. Lozano. 2017. Neurodegeneration. Neurodegeneration 53 57 .
Dustin Anderson, Grayson Beecher & Fang Ba. (2017) Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms. Parkinson's Disease 2017, pages 1-13.
Crossref
Paolo Mazzone, Osvaldo Vilela Filho, Fabio Viselli, Angelo Insola, Stefano Sposato, Flora Vitale & Eugenio Scarnati. (2016) Our first decade of experience in deep brain stimulation of the brainstem: elucidating the mechanism of action of stimulation of the ventrolateral pontine tegmentum. Journal of Neural Transmission 123:7, pages 751-767.
Crossref
Kaoru Takakusaki, Ryosuke Chiba, Tsukasa Nozu & Toshikatsu Okumura. (2015) Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systems. Journal of Neural Transmission 123:7, pages 695-729.
Crossref
Nadine K. Gut & Philip Winn. (2016) The pedunculopontine tegmental nucleus-A functional hypothesis from the comparative literature. Movement Disorders 31:5, pages 615-624.
Crossref
Thomas Wichmann & Mahlon R. DeLong. (2016) Deep Brain Stimulation for Movement Disorders of Basal Ganglia Origin: Restoring Function or Functionality?. Neurotherapeutics 13:2, pages 264-283.
Crossref
Angelo Insola, Luca Padua, Paolo Mazzone & Massimiliano Valeriani. (2015) Low- and high-frequency subcortical SEP amplitude reduction during pure passive movement. Clinical Neurophysiology 126:12, pages 2366-2375.
Crossref
Edgar Garcia-Rill, Brennon Luster, Stasia D’Onofrio, Susan Mahaffey, Veronica Bisagno & Francisco J. Urbano. (2015) Pedunculopontine arousal system physiology – Deep brain stimulation (DBS). Sleep Science 8:3, pages 153-161.
Crossref
E. Garcia-Rill, J. Hyde, N. Kezunovic, F. J. Urbano & E. Petersen. (2014) The physiology of the pedunculopontine nucleus: implications for deep brain stimulation. Journal of Neural Transmission 122:2, pages 225-235.
Crossref
Brennon Luster, Erica Petersen & Edgar Garcia-Rill. 2015. Waking and the Reticular Activating System in Health and Disease. Waking and the Reticular Activating System in Health and Disease 255 276 .
T. Sankar & A.M. Lozano. 2015. Brain Mapping. Brain Mapping 955 964 .
Angelo Insola, Luca Padua, Paolo Mazzone, Eugenio Scarnati & Massimiliano Valeriani. (2014) Low and high-frequency somatosensory evoked potentials recorded from the human pedunculopontine nucleus. Clinical Neurophysiology 125:9, pages 1859-1869.
Crossref
Annamaria Capozzo, Flora Vitale, Claudia Mattei, Paolo Mazzone & Eugenio Scarnati. (2014) Continuous stimulation of the pedunculopontine tegmental nucleus at 40Hz affects preparative and executive control in a delayed sensorimotor task and reduces rotational movements induced by apomorphine in the 6-OHDA parkinsonian rat. Behavioural Brain Research 271, pages 333-342.
Crossref
P. Mazzone, M. Paoloni, M. Mangone, V. Santilli, A. Insola, M. Fini & E. Scarnati. (2014) Unilateral deep brain stimulation of the pedunculopontine tegmental nucleus in idiopathic Parkinson’s disease: Effects on gait initiation and performance. Gait & Posture 40:3, pages 357-362.
Crossref
Timothy L Tattersall, Peter G Stratton, Terry J Coyne, Raymond Cook, Paul Silberstein, Peter A Silburn, François Windels & Pankaj Sah. (2014) Imagined gait modulates neuronal network dynamics in the human pedunculopontine nucleus. Nature Neuroscience 17:3, pages 449-454.
Crossref
Paolo Mazzone, Stefano Sposato, Angelo Insola & Eugenio Scarnati. (2013) The Clinical Effects of Deep Brain Stimulation of the Pedunculopontine Tegmental Nucleus in Movement Disorders May Not Be Related to the Anatomical Target, Leads Location, and Setup of Electrical Stimulation. Neurosurgery 73:5, pages 894-906.
Crossref
Marie-Pierre Fournier-Gosselin, Nir Lipsman, Jean A. Saint-Cyr, Clement Hamani & Andres M. Lozano. (2013) Regional anatomy of the pedunculopontine nucleus: Relevance for deep brain stimulation. Movement Disorders 28:10, pages 1330-1336.
Crossref
Laura M Zitella, Kevin Mohsenian, Mrinal Pahwa, Cory Gloeckner & Matthew D Johnson. (2013) Computational modeling of pedunculopontine nucleus deep brain stimulation. Journal of Neural Engineering 10:4, pages 045005.
Crossref
Travis S. Tierney & Andres M. Lozano. 2013. Rehabilitation in Movement Disorders. Rehabilitation in Movement Disorders 36 43 .
. 2013. Rehabilitation in Movement Disorders. Rehabilitation in Movement Disorders 25 54 .
P. Caliandro, E. Di Sipio, A. Insola, E. Scarnati, L. Padua, G. Russo, E. Granieri & P. Mazzone. (2013) Effects of unilateral pedunculopontine stimulation on electromyographic activation patterns during gait in individual patients with Parkinson's disease. Gait & Posture 37, pages S5.
Crossref
Travis S. Tierney, Tejas Sankar & Andres M. Lozano. 2013. Stereotactic and Functional Neurosurgery. Stereotactic and Functional Neurosurgery 87 92 .
Antonella Peppe, Mariangela Pierantozzi, Valentina Baiamonte, Vincenzo Moschella, Carlo Caltagirone, Paolo Stanzione & Alessandro Stefani. (2012) Deep Brain Stimulation of Pedunculopontine Tegmental Nucleus: Role in Sleep Modulation in Advanced Parkinson Disease Patients—One-Year Follow-Up. Sleep 35:12, pages 1637-1642.
Crossref
Paolo Mazzone, Luca Padua, Gianni Falisi, Angelo Insola, Tiziana M. Florio & Eugenio Scarnati. (2012) Unilateral deep brain stimulation of the pedunculopontine tegmental nucleus improves oromotor movements in Parkinson’s disease. Brain Stimulation 5:4, pages 634-641.
Crossref
Angelo Insola, Massimiliano Valeriani & Paolo Mazzone. (2012) Targeting the Pedunculopontine Nucleus. Operative Neurosurgery 71, pages ons96-ons103.
Crossref
Iciar Aviles-Olmos, Thomas Foltynie, Jalesh Panicker, Dorothy Cowie, Patricia Limousin, Marwan Hariz, Clare J. Fowler & Ludvic Zrinzo. (2012) The surgical anatomy of the pedunculopontine nucleus cannot be disputed, buried or exhumed. Acta Neurochirurgica 154:8, pages 1531-1533.
Crossref
Paolo Mazzone, Angelo Insola, Massimiliano Valeriani, Pietro Caliandro, Stefano Sposato & Eugenio Scarnati. (2012) Uncertainty, misunderstanding and the pedunculopontine nucleus: the exhumation of an already buried dispute. Acta Neurochirurgica 154:8, pages 1527-1529.
Crossref
Iciar Aviles-Olmos, Thomas Foltynie, Jalesh Panicker, Dorothy Cowie, Patricia Limousin, Marwan Hariz, Clare J. Fowler & Ludvic Zrinzo. (2012) Uncertainty, misunderstanding and the pedunculopontine nucleus. Acta Neurochirurgica 154:5, pages 839-841.
Crossref
Paolo Mazzone, Stefano Sposato, Angelo Insola & Eugenio Scarnati. (2012) A Commentary on the Lead Positioning for Deep Brain Stimulation in the Pedunculopontine Tegmental Nucleus in a Patient Affected by Multiple System Atrophy. Stereotactic and Functional Neurosurgery 90:2, pages 130-133.
Crossref
Yoland Smith, Thomas Wichmann, Stewart A Factor & Mahlon R DeLong. (2011) Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa. Neuropsychopharmacology 37:1, pages 213-246.
Crossref
Ludvic Zrinzo, Laurence V. Zrinzo, Luke A. Massey, John Thornton, Harold G. Parkes, Mark White, Tarek A. Yousry, Catherine Strand, Tamas Revesz, Patricia Limousin, Marwan I. Hariz & Janice L. Holton. (2011) Targeting of the pedunculopontine nucleus by an MRI-guided approach: a cadaver study. Journal of Neural Transmission 118:10, pages 1487-1495.
Crossref
Paolo Mazzone, Stefano Sposato, Angelo Insola & Eugenio Scarnati. (2011) The deep brain stimulation of the pedunculopontine tegmental nucleus: towards a new stereotactic neurosurgery. Journal of Neural Transmission 118:10, pages 1431-1451.
Crossref
P. Mazzone, E. Scarnati & E. Garcia-Rill. (2010) Commentary: The pedunculopontine nucleus: clinical experience, basic questions and future directions. Journal of Neural Transmission 118:10, pages 1391-1396.
Crossref
Edgar Garcia-Rill, Christen Simon, Kristen Smith, Nebosja Kezunovic & James Hyde. (2010) The pedunculopontine tegmental nucleus: from basic neuroscience to neurosurgical applications. Journal of Neural Transmission 118:10, pages 1397-1407.
Crossref
R. Ceravolo, L. Brusa, S. Galati, D. Volterrani, A. Peppe, G. Siciliano, M. Pierantozzi, V. Moschella, U. Bonuccelli, P. Stanzione & A. Stefani. (2011) Low frequency stimulation of the nucleus tegmenti pedunculopontini increases cortical metabolism in Parkinsonian patients. European Journal of Neurology 18:6, pages 842-849.
Crossref
Miet de Letter, John Van Borsel, Julie Dewulf & Patrick Santens. (2011) Dysfluencies in pure akinesia with gait freezing: Two case reports. Journal of Neurolinguistics 24:3, pages 352-356.
Crossref
Travis S. Tierney, Tejas Sankar & Andres M. Lozano. 2011. Brain Machine Interfaces: Implications for Science, Clinical Practice and Society. Brain Machine Interfaces: Implications for Science, Clinical Practice and Society 83 95 .
A. Peppe, M. Pierantozzi, C. Chiavalon, F. Marchetti, C. Caltagirone, M. Musicco, P. Stanzione & A. Stefani. (2010) Deep brain stimulation of the pedunculopontine tegmentum and subthalamic nucleus: Effects on gait in Parkinson's disease. Gait & Posture 32:4, pages 512-518.
Crossref
Felix Rauch, Kerstin Schwabe & Joachim K. Krauss. (2010) Effect of deep brain stimulation in the pedunculopontine nucleus on motor function in the rat 6-hydroxydopamine Parkinson model. Behavioural Brain Research 210:1, pages 46-53.
Crossref
A. Stefani, M. Pierantozzi, R. Ceravolo, L. Brusa, S. Galati & P. Stanzione. (2010) Deep Brain Stimulation of Pedunculopontine Tegmental Nucleus (PPTg) Promotes Cognitive and Metabolic Changes: A Target-Specific Effect or Response to a Low-Frequency Pattern of Stimulation?. Clinical EEG and Neuroscience 41:2, pages 82-86.
Crossref
Alberto Costa. (2010) Effects of deep brain stimulation of the pedunculopontine area on working memory tasks in patients with Parkinson's. Parkinsonism & Related Disorders 16:2, pages 149.
Crossref
Eugenio Scarnati. (2010) The deep brain stimulation of the pedunculopontine tegmental nucleus: The (un)certainty of the stimulating site. Parkinsonism & Related Disorders 16:2, pages 148.
Crossref
Stefani Alessandro, Roberto Ceravolo, Livia Brusa, Mariangela Pierantozzi, Alberto Costa, Salvatore Galati, Fabio Placidi, Andrea Romigi, Cesare Iani, Francesco Marzetti & Antonella Peppe. (2010) Non-motor functions in parkinsonian patients implanted in the pedunculopontine nucleus: Focus on sleep and cognitive domains. Journal of the Neurological Sciences 289:1-2, pages 44-48.
Crossref
M. U. Ferraye, B. Debu, V. Fraix, L. Goetz, C. Ardouin, J. Yelnik, C. Henry-Lagrange, E. Seigneuret, B. Piallat, P. Krack, J.-F. Le Bas, A.-L. Benabid, S. Chabardes & P. Pollak. (2009) Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease. Brain 133:1, pages 205-214.
Crossref
E. Elgh, M. Domellöf, J. Linder, M. Edström, H. Stenlund & L. Forsgren. (2009) Cognitive function in early Parkinson’s disease: a population-based study. European Journal of Neurology 16:12, pages 1278-1284.
Crossref
Caroline Moreau, Luc Defebvre, David Devos, Fabio Marchetti, Alain Destée, Alessandro Stefani & Antonella Peppe. (2009) STN versus PPN‐DBS for alleviating freezing of gait: Toward a frequency modulation approach?. Movement Disorders 24:14, pages 2164-2166.
Crossref
Livia Brusa, Cesare Iani, Roberto Ceravolo, Salvatore Galati, Vincenzo Moschella, Francesco Marzetti, Paolo Stanzione & Alessandro Stefani. (2009) Implantation of the nucleus tegmenti pedunculopontini in a PSP‐P patient: Safe procedure, modest benefits. Movement Disorders 24:13, pages 2020-2022.
Crossref
Annamaria Capozzo, Tiziana Florio, Giuseppina Confalone, Daniela Minchella, Paolo Mazzone & Eugenio Scarnati. (2008) Low frequency stimulation of the pedunculopontine nucleus modulates electrical activity of subthalamic neurons in the rat. Journal of Neural Transmission 116:1, pages 51-56.
Crossref
Alessandro Stefani, Salvatore Galati, Mariangela Pierantozzi, Antonella Peppe, Livia Brusa, Vincenzo Moschella, Francesco Marzetti & Paolo Stanzione. 2009. The Basal Ganglia IX. The Basal Ganglia IX 573 587 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.