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Original Article

The challenge of evaluating freezing of gait in patients with Parkinson's disease

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Pages S16-S18 | Received 15 Jun 2008, Accepted 03 Sep 2008, Published online: 06 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Nora Vanegas-Arroyave & Joseph Jankovic. (2023) Spinal cord stimulation for gait disturbances in Parkinson’s disease. Expert Review of Neurotherapeutics 23:7, pages 651-659.
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Joke Spildooren, Cathérine Vinken, Laura Van Baekel & Alice Nieuwboer. (2019) Turning problems and freezing of gait in Parkinson’s disease: a systematic review and meta-analysis. Disability and Rehabilitation 41:25, pages 2994-3004.
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Alberto Cucca, Milton C Biagioni, Jori E Fleisher, Shashank Agarwal, Andre Son, Pawan Kumar, Miroslaw Brys & Alessandro Di Rocco. (2016) Freezing of Gait in Parkinson’s Disease: From Pathophysiology to Emerging Therapies. Neurodegenerative Disease Management 6:5, pages 431-446.
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Articles from other publishers (48)

Dione Y. L. Quek, Natasha Taylor, Moran Gilat, Simon J. G. Lewis & Kaylena A. Ehgoetz Martens. (2024) Effect of dopamine on limbic network connectivity at rest in Parkinson’s disease patients with freezing of gait. Translational Neuroscience 15:1.
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Banashree Mondal, Supriyo Choudhury, Rebecca Banerjee, Akash Roy, Koustav Chatterjee, Purba Basu, Ravi Singh, Saptak Halder, Shantanu Shubham, Stuart N. Baker, Mark R. Baker & Hrishikesh Kumar. (2024) Effects of non-invasive vagus nerve stimulation on clinical symptoms and molecular biomarkers in Parkinson’s disease. Frontiers in Aging Neuroscience 15.
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Carolina I. Conde, Charlotte Lang, Christian R. Baumann, Chris A. Easthope, William R. Taylor & Deepak K. Ravi. (2023) Triggers for freezing of gait in individuals with Parkinson’s disease: a systematic review. Frontiers in Neurology 14.
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Hsiao-Lung Chan, Ya-Ju Chang, Rou-Shayn Chen, Cheng-Chung Kuo, Yi-Tao Chen, Jiunn-Woei Liaw, Guo-Sheng Liao & Wan-Ting Lin. (2023) Laser-light Visual Cueing Shoes with Foot Pressures and Inertial Sensing for Individuals with Parkinson’s Disease * . Laser-light Visual Cueing Shoes with Foot Pressures and Inertial Sensing for Individuals with Parkinson’s Disease * .
Galit Yogev-Seligmann, Naomi Josman, Noemi Bitterman, Sara Rosenblum, Sitar Naaman & Yafit Gilboa. (2023) The development of a home-based technology to improve gait in people with Parkinson's disease: a feasibility study. BioMedical Engineering OnLine 22:1.
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Diana Denk, Talia Herman, Demi Zoetewei, Pieter Ginis, Marina Brozgol, Pablo Cornejo Thumm, Eva Decaluwe, Natalie Ganz, Luca Palmerini, Nir Giladi, Alice Nieuwboer & Jeffrey M Hausdorff. (2022) Daily-Living Freezing of Gait as Quantified Using Wearables in People With Parkinson Disease: Comparison With Self-Report and Provocation Tests. Physical Therapy 102:12.
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Mitra Afshari, Andrea V. Hernandez, Jorik Nonnekes, Bastiaan R. Bloem & Christopher G. Goetz. (2022) Are Virtual Objective Assessments of Fall‐Risk Feasible and Safe for People with Parkinson's Disease?. Movement Disorders Clinical Practice 9:6, pages 799-804.
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Bohan Shi, Arthur Tay, Wang Lok Au, Dawn M. L. Tan, Nicole S. Y. Chia & Shih-Cheng Yen. (2022) Detection of Freezing of Gait Using Convolutional Neural Networks and Data From Lower Limb Motion Sensors. IEEE Transactions on Biomedical Engineering 69:7, pages 2256-2267.
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Banashree Mondal, Supriyo Choudhury, Rebecca Banerjee, Akash Roy, Koustav Chatterjee, Purba Basu, Ravi Singh, Saptak Halder, Shantanu Shubham, Stuart N. Baker, Mark R. Baker & Hrishikesh Kumar. (2021) RETRACTED ARTICLE: Non-invasive vagus nerve stimulation improves clinical and molecular biomarkers of Parkinson’s disease in patients with freezing of gait. npj Parkinson's Disease 7:1.
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Cameron Diep, Johanna O’Day, Yasmine Kehnemouyi, Gary Burnett & Helen Bronte-Stewart. (2021) Gait Parameters Measured from Wearable Sensors Reliably Detect Freezing of Gait in a Stepping in Place Task. Sensors 21:8, pages 2661.
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Jay L. Alberts, Mandy Miller Koop, Marisa P. McGinley, Amanda L. Penko, Hubert H. Fernandez, Steven Shook, Robert A. Bermel, André Machado & Anson B. Rosenfeldt. (2021) Use of a Smartphone to Gather Parkinson’s Disease Neurological Vital Signs during the COVID-19 Pandemic. Parkinson's Disease 2021, pages 1-7.
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Jochen Klucken, Juergen Winkler, Rejko Krüger & Wolfgang Jost. (2020) Die Geschichte des ‚Freezing-of-gait‘ beim Parkinson-Syndrom – vom Phänomen zum Symptom. Fortschritte der Neurologie · Psychiatrie 88:09, pages 573-581.
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H. Gokul, Prithvi Suresh, B. Hari Vignesh, R. Pravin Kumaar & Vineeth Vijayaraghavan. (2020) Gait Recovery System for Parkinson’s Disease using Machine Learning on Embedded Platforms. Gait Recovery System for Parkinson’s Disease using Machine Learning on Embedded Platforms.
Bohan Shi, Shih Cheng Yen, Arthur Tay, Dawn M.L. Tan, Nicole S. Y. Chia & W.L. Au. (2020) Convolutional Neural Network for Freezing of Gait Detection Leveraging the Continuous Wavelet Transform on Lower Extremities Wearable Sensors Data. Convolutional Neural Network for Freezing of Gait Detection Leveraging the Continuous Wavelet Transform on Lower Extremities Wearable Sensors Data.
Johanna O’Day, Judy Syrkin-Nikolau, Chioma Anidi, Lukasz Kidzinski, Scott Delp & Helen Bronte-Stewart. (2020) The turning and barrier course reveals gait parameters for detecting freezing of gait and measuring the efficacy of deep brain stimulation. PLOS ONE 15:4, pages e0231984.
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Femke Hulzinga, Alice Nieuwboer, Bauke W. Dijkstra, Martina Mancini, Carolien Strouwen, Bastiaan R. Bloem & Pieter Ginis. (2020) The New Freezing of Gait Questionnaire: Unsuitable as an Outcome in Clinical Trials?. Movement Disorders Clinical Practice 7:2, pages 199-205.
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Luigi Borzì, Marilena Varrecchia, Gabriella Olmo, Carlo Alberto Artusi, Margherita Fabbri, Mario Giorgio Rizzone, Alberto Romagnolo, Maurizio Zibetti & Leonardo Lopiano. (2019) Home monitoring of motor fluctuations in Parkinson’s disease patients. Journal of Reliable Intelligent Environments 5:3, pages 145-162.
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Joyce B. Weersink, Charlotte Eikelboom, Zeus T. Dominguez Vega, Natasha M. Maurits & Bauke M. de Jong. (2018) Forward arm extension as a cue for gait initiation in Parkinson's patients. Movement Disorders 33:11, pages 1826-1827.
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Caihong Zhou, Xiaoling Zhong, Yongzhe Yang, Wanqun Yang, Lijuan Wang, Yuhu Zhang, Kun Nie, Jianmin Xu & Biao Huang. (2018) Alterations of regional homogeneity in freezing of gait in Parkinson's disease. Journal of the Neurological Sciences 387, pages 54-59.
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Tao-Mian Mi, Shan-Shan Mei, Pei-Peng Liang, Lin-Lin Gao, Kun-Cheng Li, Tao Wu & Piu Chan. (2017) Altered resting-state brain activity in Parkinson’s disease patients with freezing of gait. Scientific Reports 7:1.
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Antonio Suppa, Ardian Kita, Giorgio Leodori, Alessandro Zampogna, Ettore Nicolini, Paolo Lorenzi, Rosario Rao & Fernanda Irrera. (2017) l-DOPA and Freezing of Gait in Parkinson’s Disease: Objective Assessment through a Wearable Wireless System. Frontiers in Neurology 8.
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Joke Spildooren, Sarah Vercruysse, Elke Heremans, Brook Galna, Geert Verheyden, Griet Vervoort & Alice Nieuwboer. (2017) Influence of Cueing and an Attentional Strategy on Freezing of Gait in Parkinson Disease During Turning. Journal of Neurologic Physical Therapy 41:2, pages 129-135.
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M. J. Nijkrake & S. Keus. 2017. Geriatrie in de fysiotherapie en kinesitherapie. Geriatrie in de fysiotherapie en kinesitherapie 181 194 .
Claudia Barthel, Elizabeth Mallia, Bettina Debû, Bastiaan R. Bloem & Murielle Ursulla Ferraye. (2016) The Practicalities of Assessing Freezing of Gait. Journal of Parkinson's Disease 6:4, pages 667-674.
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William R. Young, Lauren Shreve, Emma Jane Quinn, Cathy Craig & Helen Bronte-Stewart. (2016) Auditory cueing in Parkinson's patients with freezing of gait. What matters most: Action-relevance or cue-continuity?. Neuropsychologia 87, pages 54-62.
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Yan Zhao, Jorik Nonnekes, Erik J. M. Storcken, Sabine Janssen, Erwin E. H. van Wegen, Bastiaan R. Bloem, Lucille D. A. Dorresteijn, Jeroen P. P. van Vugt, Tjitske Heida & Richard J. A. van Wezel. (2016) Feasibility of external rhythmic cueing with the Google Glass for improving gait in people with Parkinson’s disease. Journal of Neurology 263:6, pages 1156-1165.
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Lucia Pepa, Marianna Capecci, Federica Verdini, Maria Gabriella Ceravolo & Luca Spalazzi. (2015) An architecture to manage motor disorders in Parkinson's disease. An architecture to manage motor disorders in Parkinson's disease.
Sinziana Mazilu, Alberto Calatroni, Eran Gazit, Anat Mirelman, Jeffrey M. Hausdorff & Gerhard Troster. (2015) Prediction of Freezing of Gait in Parkinson's From Physiological Wearables: An Exploratory Study. IEEE Journal of Biomedical and Health Informatics 19:6, pages 1843-1854.
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Manuela Pilleri, Luca Weis, Letizia Zabeo, Konstantinos Koutsikos, Roberta Biundo, Silvia Facchini, Simonetta Rossi, Stefano Masiero & Angelo Antonini. (2015) Overground robot assisted gait trainer for the treatment of drug-resistant freezing of gait in Parkinson disease. Journal of the Neurological Sciences 355:1-2, pages 75-78.
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Sinziana Mazilu, Ulf Blanke, Moran Dorfman, Eran Gazit, Anat Mirelman, Jeffrey M. Hausdorff & Gerhard Tröster. (2015) A Wearable Assistant for Gait Training for Parkinson’s Disease with Freezing of Gait in Out-of-the-Lab Environments. ACM Transactions on Interactive Intelligent Systems 5:1, pages 1-31.
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Anina Vogler, Jorina Janssens, Thomas Nyffeler, Stephan Bohlhalter & Tim Vanbellingen. (2015) German Translation and Validation of the “Freezing of Gait Questionnaire” in Patients with Parkinson’s Disease. Parkinson's Disease 2015, pages 1-5.
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Brett W. Fling, Rajal G. Cohen, Martina Mancini, Samuel D. Carpenter, Damien A. Fair, John G. Nutt & Fay B. Horak. (2014) Functional Reorganization of the Locomotor Network in Parkinson Patients with Freezing of Gait. PLoS ONE 9:6, pages e100291.
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Alice Nieuwboer & Nir Giladi. (2013) Characterizing freezing of gait in Parkinson's disease: Models of an episodic phenomenon. Movement Disorders 28:11, pages 1509-1519.
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Brett W. Fling, Rajal G. Cohen, Martina Mancini, John G. Nutt, Damian A. Fair & Fay B. Horak. (2013) Asymmetric pedunculopontine network connectivity in parkinsonian patients with freezing of gait. Brain 136:8, pages 2405-2418.
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Gammon M. Earhart & Michael J. Falvo. 2011. Comprehensive Physiology. Comprehensive Physiology 833 848 .
J. Nantel, J.C. McDonald, S. Tan & H. Bronte-Stewart. (2012) Deficits in visuospatial processing contribute to quantitative measures of freezing of gait in Parkinson’s disease. Neuroscience 221, pages 151-156.
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L Niu, L-Y Ji, J-M Li, D-S Zhao, G Huang, W-P Liu, Y Qu, L-T Ma & X-T Ji. (2012) Effect of Bilateral Deep Brain Stimulation of the Subthalamic Nucleus on Freezing of Gait in Parkinson's Disease. Journal of International Medical Research 40:3, pages 1108-1113.
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Tiffany R. Morris, Catherine Cho, Valentina Dilda, James M. Shine, Sharon L. Naismith, Simon J.G. Lewis & Steven T. Moore. (2012) A comparison of clinical and objective measures of freezing of gait in Parkinson's disease. Parkinsonism & Related Disorders 18:5, pages 572-577.
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J.M. Shine, S.T. Moore, S.J. Bolitho, T.R. Morris, V. Dilda, S.L. Naismith & S.J.G. Lewis. (2012) Assessing the utility of Freezing of Gait Questionnaires in Parkinson’s Disease. Parkinsonism & Related Disorders 18:1, pages 25-29.
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Julie Nantel, Camille de Solages & Helen Bronte-Stewart. (2011) Repetitive stepping in place identifies and measures freezing episodes in subjects with Parkinson's disease. Gait & Posture 34:3, pages 329-333.
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Johanna G. Kalf, Marten Munneke & Bastiaan R. Bloem. 2011. Handbook of Atypical Parkinsonism. Handbook of Atypical Parkinsonism 142 159 .
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Joke Spildooren, Sarah Vercruysse, Kaat Desloovere, Wim Vandenberghe, Eric Kerckhofs & Alice Nieuwboer. (2010) Freezing of gait in Parkinson's disease: The impact of dual‐tasking and turning. Movement Disorders 25:15, pages 2563-2570.
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Inbal Maidan, Meir Plotnik, Anat Mirelman, Aner Weiss, Nir Giladi & Jeffrey M. Hausdorff. (2010) Heart rate changes during freezing of gait in patients with Parkinson's disease. Movement Disorders 25:14, pages 2346-2354.
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Kerstin Ziegler, Frauke Schroeteler, Andres O. Ceballos‐Baumann & Urban M. Fietzek. (2010) A new rating instrument to assess festination and freezing gait in Parkinsonian patients. Movement Disorders 25:8, pages 1012-1018.
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Chad A. Lebold & Q. J. Almeida. (2010) Evaluating the Contributions of Dynamic Flow to Freezing of Gait in Parkinson's Disease. Parkinson's Disease 2010, pages 1-7.
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