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Original Article

Ocimum sanctum Modulates Selenite-Induced Cataractogenic Changes and Prevents Rat Lens Opacification

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Pages 583-591 | Received 14 Nov 2003, Accepted 16 Sep 2004, Published online: 02 Jul 2009

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Read on this site (6)

Hatice Tuba Atalay, Ahmet Yucel Ucgul, Ummuhani Ozel Turkcu, Mehmet Cuneyt Ozmen, Samet Yilmaz & Ayse Bilgihan. (2020) The Effect of Sildenafil on Selenite-Induced Cataract in Rats. Current Eye Research 45:9, pages 1082-1088.
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Thiraviyam Anand, Muniyandi Anbukkarasi, P. Archana Teresa, Philip Aloysius Thomas & Pitchairaj Geraldine. (2020) Evaluation of the Putative Efficacy of a Methanolic Extract of Ocimum Basilicum in Preventing Disruption of Structural Proteins in an in Vitro System of Selenite-induced Cataractogenesis. Current Eye Research 45:6, pages 696-704.
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R. Thiagarajan & R. Manikandan. (2013) Antioxidants and cataract. Free Radical Research 47:5, pages 337-345.
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M. Isai, R. Elanchezhian, M. Sakthivel, A. Chinnakkaruppan, M. Rajamohan, C. Nelson Jesudasan, P. A. Thomas & P. Geraldine. (2009) Anticataractogenic Effect of an Extract of the Oyster Mushroom, Pleurotus ostreatus, in an Experimental Animal Model. Current Eye Research 34:4, pages 264-273.
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R. Elanchezhian, E. Ramesh, M. Sakthivel, M. Isai, P. Geraldine, M. Rajamohan, C. Nelson Jesudasan & P. A. Thomas. (2007) Acetyl-L-Carnitine Prevents Selenite-Induced Cataractogenesis in an Experimental Animal Model. Current Eye Research 32:11, pages 961-971.
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Ramazan Yağci, Bahri Aydin, Mesut Erdurmuş, Remzi Karadağ, Ahmet Gürel, Mustafa Durmuş & Ramazan Yiğitoğlu. (2006) Use of Melatonin to Prevent Selenite-Induced Cataract Formation in Rat Eyes. Current Eye Research 31:10, pages 845-850.
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Articles from other publishers (33)

Haamid Rasheed, Suhail Ahmed, Harjeet Singh & Alok Sharma. 2022. Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda. Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda 108 147 .
Thiraviyam Anand, Muniyandi Anbukkarasi, Philip Aloysius Thomas & Pitchairaj Geraldine. (2021) A comparison between plain eugenol and eugenol-loaded chitosan nanoparticles for prevention of in vitro selenite-induced cataractogenesis. Journal of Drug Delivery Science and Technology 65, pages 102696.
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Somaye Beigi, Majid Azizi & Marcello Iriti. (2020) Application of Super Absorbent Polymer and Plant Mucilage Improved Essential Oil Quantity and Quality of Ocimum basilicum var. Keshkeni Luvelou. Molecules 25:11, pages 2503.
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R. Manikandan. (2020) Resveratrol Prevents Cataract Formation by Inhibiting Pro-inflammatory Mediator-induced Dysregulation of Lens Calcium. Journal of Ophthalmic Science 2:3, pages 14-35.
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Segewkal H. Heruye, Leonce N. Maffofou Nkenyi, Neetu U. Singh, Dariush Yalzadeh, Kalu K. Ngele, Ya-Fatou Njie-Mbye, Sunny E. Ohia & Catherine A. Opere. (2020) Current Trends in the Pharmacotherapy of Cataracts. Pharmaceuticals 13:1, pages 15.
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Shahid AkbarShahid Akbar. 2020. Handbook of 200 Medicinal Plants. Handbook of 200 Medicinal Plants 1339 1357 .
Yasaswi Maddirala, Shakila Tobwala, Humeyra Karacal & Nuran Ercal. (2017) Prevention and reversal of selenite-induced cataracts by N-acetylcysteine amide in Wistar rats. BMC Ophthalmology 17:1.
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Mahalingam Sundararajan, Philip A. Thomas, Karuppan Babyshalini & Pitchairaj Geraldine. (2017) Identification of phytoconstituents and in-vitro evaluation of the putative anticataractogenic effect of an ethanolic root extract of Leucas aspera. Biomedicine & Pharmacotherapy 85, pages 87-101.
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Julie C. Lim, Ankita Umapathy & Paul J. Donaldson. (2016) Tools to fight the cataract epidemic: A review of experimental animal models that mimic age related nuclear cataract. Experimental Eye Research 145, pages 432-443.
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Suchita Dubey, Prakash Deep & Amrit K. Singh. (2016) Phytochemical characterization and evaluation of anticataract potential of seabuckthorn leaf extract. Veterinary Ophthalmology 19:2, pages 144-148.
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Thirumurthy Velpandian, Aruna Singh & Rama Jayasundar. 2016. Pharmacology of Ocular Therapeutics. Pharmacology of Ocular Therapeutics 517 535 .
Vasudevanpillai Sreelakshmi, Vilasini Sasikala & Annie Abraham. (2015) Luteolin Supplementation Prevents Selenite‐Induced Cataractogenesis in Sprague Dawley Rat Pups . Chemistry & Biodiversity 12:12, pages 1881-1890.
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Rasiah Pratheepa Kumari, Srinivasagan Ramkumar, Bency Thankappan & Kumarasamy Anbarasu. 2015. Studies on the Cornea and Lens. Studies on the Cornea and Lens 287 315 .
Ketham Haritha, Bellamkonda Ramesh & Desireddy Saralakumari. (2014) Effect of Aloe vera gel on antioxidant enzymes in streptozotocin-induced cataractogenesis in male and female Wistar rats. Journal of Acute Medicine 4:1, pages 38-44.
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V. Sasikala, B. N. Rooban, V. Sahasranamam & Annie Abraham. (2013) Rutin ameliorates free radical mediated cataract by enhancing the chaperone activity of α-crystallin. Graefe's Archive for Clinical and Experimental Ophthalmology 251:7, pages 1747-1755.
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Asha Radha, Sudha Devi Rukhmini, Sasikala Vilasini, Priya Rajan Sakunthala, Balachandran Sreedharan, Mohanan Puzhavoorparambil Velayudhan & Annie Abraham. (2012) Bioactive Derivatives of Curcumin Attenuate Cataract Formation In Vitro . Chemical Biology & Drug Design 80:6, pages 887-892.
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Thirugnanasambandhar Sivasubramania Anitha, Thangaraj Annadurai, Philip A. Thomas & Pitchairaj Geraldine. (2010) Prevention of Selenite-Induced Cataractogenesis by an Ethanolic Extract of Cineraria maritima: An Experimental Evaluation of the Traditional Eye Medication. Biological Trace Element Research 143:1, pages 425-436.
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B. N. Rooban, V. Sasikala, V. Sahasranamam & Annie Abraham. (2010) Vitex negundo Modulates Selenite-Induced Opacification and Cataractogensis in Rat Pups. Biological Trace Element Research 138:1-3, pages 282-292.
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V. SasikalaB.N. RoobanS.G. Siva PriyaV. SahasranamamAnnie Abraham. (2010) Moringa oleifera Prevents Selenite-Induced Cataractogenesis in Rat Pups . Journal of Ocular Pharmacology and Therapeutics 26:5, pages 441-447.
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V. Gayathri Devi, B.N. Rooban, V. Sasikala, V. Sahasranamam & Annie Abraham. (2010) Isorhamnetin-3-glucoside alleviates oxidative stress and opacification in selenite cataract in vitro. Toxicology in Vitro 24:6, pages 1662-1669.
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Suresh K. Gupta, Vivekananthan Kalaiselvan, Sushma Srivastava, Rohit Saxena & Shyam S. Agrawal. (2009) Trigonella foenum-graecum (Fenugreek) Protects Against Selenite-Induced Oxidative Stress in Experimental Cataractogenesis. Biological Trace Element Research 136:3, pages 258-268.
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K.N. Dailami, M. Azadbakht, Z.R. Pharm & M. Lashgari. (2010) Prevention of Selenite-induced Cataractogenesis by Origanum vulgare Extract. Pakistan Journal of Biological Sciences 13:15, pages 743-747.
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Zuzana Kyselova. (2010) Different experimental approaches in modelling cataractogenesis. Interdisciplinary Toxicology 3:1.
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Nabanita Halder, Sujata Joshi, Tapas Chandra Nag, Radhika Tandon & Suresh Kumar Gupta. (2009) Ocimum sanctum extracts attenuate hydrogen peroxide induced cytotoxic ultrastructural changes in human lens epithelial cells . Phytotherapy Research 23:12, pages 1734-1737.
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Alireza JavadzadehAmir GhorbanihaghjoSara AramiNadereh RashtchizadehMehran MesgariMandana RafeeyYadollah Omidi. (2009) Prevention of Selenite-Induced Cataractogenesis in Wistar Albino Rats by Aqueous Extract of Garlic. Journal of Ocular Pharmacology and Therapeutics 25:5, pages 395-400.
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R. Manikandan, R. Thiagarajan, S. Beulaja, S. Chindhu, K. Mariammal, G. Sudhandiran & M. Arumugam. (2009) Anti-cataractogenic effect of curcumin and aminoguanidine against selenium-induced oxidative stress in the eye lens of Wistar rat pups: An in vitro study using isolated lens. Chemico-Biological Interactions 181:2, pages 202-209.
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B.N. Rooban, Y. Lija, P.G. Biju, V. Sasikala, V. Sahasranamam & Annie Abraham. (2009) Vitex negundo attenuates calpain activation and cataractogenesis in selenite models. Experimental Eye Research 88:3, pages 575-582.
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S Gupta, Sushma Srivastava, Renu Agarwal & Shyam Agrawal. 2009. Lycopene. Lycopene 293 308 .
Ronald N. Kostoff. (2008) Literature-related discovery (LRD): Potential treatments for cataracts. Technological Forecasting and Social Change 75:2, pages 215-225.
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M. Sakthivel, R. Elanchezhian, E. Ramesh, M. Isai, C. Nelson Jesudasan, P.A. Thomas & P. Geraldine. (2008) Prevention of selenite-induced cataractogenesis in Wistar rats by the polyphenol, ellagic acid. Experimental Eye Research 86:2, pages 251-259.
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P.G. Biju, V. Gayathri Devi, Y. Lija & Annie Abraham. (2007) Protection Against Selenite Cataract in Rat Lens by Drevogenin D, a Triterpenoid Aglycone from Dregea volubilis . Journal of Medicinal Food 10:2, pages 308-315.
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Y. Lija, P. G. Biju, A. Reeni, T. R. Cibin, V. Sahasranamam & Annie Abraham. (2006) Modulation of selenite cataract by the flavonoid fraction ofEmilia sonchifolia in experimental animal models. Phytotherapy Research 20:12, pages 1091-1095.
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Eshrat M. Halim & A. K. Mukhopadhyay. (2006) Effect ofOcimum sanctum (Tulsi) and vitamin E on biochemical parameters and retinopathy in streptozotocin induced diabetic rats. Indian Journal of Clinical Biochemistry 21:2, pages 181-188.
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