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Original Article

Nitrite-Modified Extracellular Matrix Proteins Deleteriously Affect Retinal Pigment Epithelial Cell Function and Viability: A Comparison Study with Nonenzymatic Glycation Mechanisms

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Pages 691-702 | Received 19 Jul 2004, Accepted 20 Oct 2004, Published online: 02 Jul 2009

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David C. Paik, Lynne Y. Saito, Dorcas D. Sugirtharaj & Jeffrey W. Holmes. (2006) Nitrite-Induced Cross-Linking Alters Remodeling and Mechanical Properties of Collagenous Engineered Tissues. Connective Tissue Research 47:3, pages 163-176.
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Zhiyue Wang, Xinyu Huang, Xiao Lv, Chao Chen, Shen Qu, Xiaoyu Ma, Li Zhang & Yanlong Bi. (2022) Bioinformatic analysis identifies potential key genes in the pathogenesis of age-related macular degeneration. Indian Journal of Ophthalmology 70:9, pages 3347.
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Shreya Somasundaran, Ian J. Constable, Carla B. Mellough & Livia S. Carvalho. (2020) Retinal pigment epithelium and age‐related macular degeneration: A review of major disease mechanisms. Clinical & Experimental Ophthalmology 48:8, pages 1043-1056.
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Mark A. Fields, Lucian V. Del Priore, Ron A. Adelman & Lawrence J. Rizzolo. (2020) Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier. Progress in Retinal and Eye Research 76, pages 100803.
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Jie Gong, Hui Cai, Scott Noggle, Daniel Paull, Lawrence J. Rizzolo, Lucian V. Del Priore & Mark A. Fields. (2020) Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions. Stem Cells Translational Medicine 9:3, pages 364-376.
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Steven S. Eamegdool, Ephrem I. Sitiwin, Adrian V. Cioanca & Michele C. Madigan. (2020) Extracellular matrix and oxidative stress regulate human retinal pigment epithelium growth. Free Radical Biology and Medicine 146, pages 357-371.
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Hui Cai, Jie Gong, Laura Abriola, Denton Hoyer, NYSCF Global Stem Cell Array Team, Scott Noggle, Daniel Paull, Lucian V. Del Priore & Mark A. Fields. (2019) High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD. Experimental Eye Research 185, pages 107641.
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Mai T. Thao, Devi Kalyan Karumanchi, Sally M. Yacout & Elizabeth R. Gaillard. (2018) Nitrite ion modifies tyrosine and lysine residues of extracellular matrix proteins. Nitric Oxide 79, pages 51-56.
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Mark A. Fields, Hannah E. Bowrey, Jie Gong, Ernesto F. Moreira, Hui Cai & Lucian V. Del Priore. (2017) Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells. PLOS ONE 12:5, pages e0177763.
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Mark Fields, Hui Cai, Jie Gong & Lucian Del Priore. (2016) Potential of Induced Pluripotent Stem Cells (iPSCs) for Treating Age-Related Macular Degeneration (AMD). Cells 5:4, pages 44.
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Mai T. Thao & Elizabeth R. Gaillard. (2016) The glycation of fibronectin by glycolaldehyde and methylglyoxal as a model for aging in Bruch’s membrane. Amino Acids 48:7, pages 1631-1639.
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S. Bashir, T. Wang, Y.-P. Chen & J. Louise Liu. 2015. Oxidative Stress: Diagnostics, Prevention, and Therapy Volume 2. Oxidative Stress: Diagnostics, Prevention, and Therapy Volume 2 463 502 .
Stylianos A. Kandarakis, Christina Piperi, Fotis Topouzis & Athanasios G. Papavassiliou. (2014) Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases. Progress in Retinal and Eye Research 42, pages 85-102.
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Mai T. Thao, Daniel J. Renfus, James Dillon & Elizabeth R. Gaillard. (2013) A2E‐Mediated Photochemical Modification to Fibronectin and its Implications to Age‐Related Changes in Bruch's Membrane . Photochemistry and Photobiology 90:2, pages 329-334.
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L.S. Murdaugh, Z. Wang, L.V. Del Priore, J. Dillon & E.R. Gaillard. (2010) Age-related accumulation of 3-nitrotyrosine and nitro-A2E in human Bruch's membrane. Experimental Eye Research 90:5, pages 564-571.
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L.S. Murdaugh, J. Dillon & E.R. Gaillard. (2009) Modifications to the basement membrane protein laminin using glycolaldehyde and A2E: A model for aging in Bruch's membrane. Experimental Eye Research 89:2, pages 187-192.
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