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Original Article

Evaluation of an Ex Vivo Model Implication for Carrier-Mediated Retinal Drug Delivery

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Pages 415-426 | Received 11 Nov 2005, Accepted 19 Feb 2006, Published online: 02 Jul 2009

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Victor H Barocas & Ram K Balachandran. (2008) Sustained transscleral drug delivery. Expert Opinion on Drug Delivery 5:1, pages 1-10.
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Kumar G Janoria, Sriram Gunda, Sai HS Boddu & Ashim K Mitra. (2007) Novel approaches to retinal drug delivery. Expert Opinion on Drug Delivery 4:4, pages 371-388.
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Liang Jin, Yijun Pan, Natalie Lan Linh Tran, Leon N. Polychronopoulos, Aparna Warrier, Kim L. R. Brouwer & Joseph A. Nicolazzo. (2020) Intestinal Permeability and Oral Absorption of Selected Drugs Are Reduced in a Mouse Model of Familial Alzheimer’s Disease. Molecular Pharmaceutics 17:5, pages 1527-1537.
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Di Huang, Ying-Shan Chen & Ilva D. Rupenthal. (2018) Overcoming ocular drug delivery barriers through the use of physical forces. Advanced Drug Delivery Reviews 126, pages 96-112.
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Karen Peynshaert, Joke Devoldere, Stefaan C. De Smedt & Katrien Remaut. (2018) In vitro and ex vivo models to study drug delivery barriers in the posterior segment of the eye. Advanced Drug Delivery Reviews 126, pages 44-57.
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H. Skottman, J. Muranen, H. Lähdekorpi, E. Pajula, K. Mäkelä, L. Koivusalo, A. Koistinen, H. Uusitalo, K. Kaarniranta & K. Juuti-Uusitalo. (2017) Contacting co-culture of human retinal microvascular endothelial cells alters barrier function of human embryonic stem cell derived retinal pigment epithelial cells. Experimental Cell Research 359:1, pages 101-111.
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Kati-Sisko Vellonen, Melina Malinen, Eliisa Mannermaa, Astrid Subrizi, Elisa Toropainen, Yan-Ru Lou, Heidi Kidron, Marjo Yliperttula & Arto Urtti. (2014) A critical assessment of in vitro tissue models for ADME and drug delivery. Journal of Controlled Release 190, pages 94-114.
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Peng Chen, Hao Chen, Xinjie Zang, Min Chen, Haoran Jiang, Shasha Han & Xianggen Wu. (2013) Expression of Efflux Transporters in Human Ocular Tissues. Drug Metabolism and Disposition 41:11, pages 1934-1948.
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Eliisa Mannermaa, Mika Reinisalo, Veli-Pekka Ranta, Kati-Sisko Vellonen, Heidi Kokki, Anni Saarikko, Kai Kaarniranta & Arto Urtti. (2010) Filter-cultured ARPE-19 cells as outer blood–retinal barrier model. European Journal of Pharmaceutical Sciences 40:4, pages 289-296.
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Paul MisselJames ChastainAshim MitraUday KompellaViral KansaraSridhar DuvvuriAniruddha AmriteNarayan Cheruvu. (2010) In Vitro Transport and Partitioning of AL-4940, Active Metabolite of Angiostatic Agent Anecortave Acetate, in Ocular Tissues of the Posterior Segment . Journal of Ocular Pharmacology and Therapeutics 26:2, pages 137-146.
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Viral KansaraYi HaoAshim K. Mitra. (2007) Dipeptide Monoester Ganciclovir Prodrugs for Transscleral Drug Delivery: Targeting the Oligopeptide Transporter on Rabbit Retina. Journal of Ocular Pharmacology and Therapeutics 23:4, pages 321-334.
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