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Original Article

Use of Melatonin to Prevent Selenite-Induced Cataract Formation in Rat Eyes

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Pages 845-850 | Received 13 Apr 2006, Accepted 05 Jul 2006, Published online: 02 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Hatice Tuba Atalay, Ahmet Yucel Ucgul, Ummuhani Ozel Turkcu, Mehmet Cuneyt Ozmen, Samet Yilmaz & Ayse Bilgihan. (2020) The Effect of Sildenafil on Selenite-Induced Cataract in Rats. Current Eye Research 45:9, pages 1082-1088.
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Zeynep Banu Doğanlar, Hande Güçlü, Özlem Öztopuz, Hakan Türkön, Ayten Dogan, Metehan Uzun & Oguzhan Doğanlar. (2019) The Role of Melatonin in Oxidative Stress, DNA Damage, Apoptosis and Angiogenesis in Fetal Eye under Preeclampsia and Melatonin Deficiency Stress. Current Eye Research 44:10, pages 1157-1169.
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Shuqin Cao, Mei Gao, Ningli Wang, Na Liu, Guanhua Du & Jianmin Lu. (2015) Prevention of Selenite-Induced Cataratogenesis by Ginkgo biloba Extract (Egb761) in Wistar Rats. Current Eye Research 40:10, pages 1028-1033.
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Seyithan Taysi, Zainab Khaleel Abdulrahman, Seydi Okumus, Elif Demir, Tuncer Demir, Muslum Akan, Edibe Saricicek, Vahap Saricicek, Adnan Aksoy & Mehmet Tarakcioglu. (2015) The radioprotective effect of Nigella sativa on nitrosative stress in lens tissue in radiation-induced cataract in rat. Cutaneous and Ocular Toxicology 34:2, pages 101-106.
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Almudena Crooke, Fernando Huete-Toral, Alejandro Martínez-Águila, Basilio Colligris & Jesus Pintor. (2012) Ocular disorders and the utility of animal models in the discovery of melatoninergic drugs with therapeutic potential. Expert Opinion on Drug Discovery 7:10, pages 989-1001.
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R. Manikandan, R. Thiagarajan, S. Beulaja, G. Sudhandiran & M. Arumugam. (2010) Effect of Curcumin on Selenite-Induced Cataractogenesis in Wistar Rat Pups. Current Eye Research 35:2, pages 122-129.
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M. Isai, R. Elanchezhian, M. Sakthivel, A. Chinnakkaruppan, M. Rajamohan, C. Nelson Jesudasan, P. A. Thomas & P. Geraldine. (2009) Anticataractogenic Effect of an Extract of the Oyster Mushroom, Pleurotus ostreatus, in an Experimental Animal Model. Current Eye Research 34:4, pages 264-273.
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Bahri Aydin, Ramazan Yagci, Fatma M. Yılmaz, Mesut Erdurmus, Remzi Karadağ, Ugurcan Keskin, Mustafa Durmus & Ramazan Yigitoglu. (2009) Prevention of Selenite-Induced Cataractogenesis by N-Acetylcysteine in Rats. Current Eye Research 34:3, pages 196-201.
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Seyithan Taysi, Ramazan Memisogullari, Mehmet Koc, Ahmet Taylan Yazici, Murat Aslankurt, Kenan Gumustekin, Behçet Al, Fatma Ozabacigil, Adnan Yilmaz & Hasan Tahsin Ozder. (2008) Melatonin reduces oxidative stress in the rat lens due to radiation-induced oxidative injury. International Journal of Radiation Biology 84:10, pages 803-808.
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Articles from other publishers (34)

Dario Rusciano & Cristina Russo. (2024) The Therapeutic Trip of Melatonin Eye Drops: From the Ocular Surface to the Retina. Pharmaceuticals 17:4, pages 441.
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Mona Nourazaran, Reza Yousefi, Faezeh Moosavi-Movahedi, Farhad Panahi, Jun Hong & Ali A. Moosavi-Movahedi. (2023) The structural and functional consequences of melatonin and serotonin on human αB-crystallin and their dual role in the eye lens transparency. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1871:5, pages 140928.
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Zhenxiang Gao, Maria Gorenflo, David C. Kaelber, Vincent M. Monnier & Rong Xu. (2023) Drug repurposing for reducing the risk of cataract extraction in patients with diabetes mellitus: integration of artificial intelligence-based drug prediction and clinical corroboration. Frontiers in Pharmacology 14.
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Arash Rakhshi Asl, Mahboobeh Ashrafi, Mahmoud Aminlari, Saba Taghavi, Behnaz Karimi & Aboutorab Tabatabaei Naini. (2022) The protective effect of pomegranate peel aqueous extract on selenite‐induced cataract in rats. Journal of Food Biochemistry 46:10.
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María Serramito, Ana F. Pereira-da-Mota, Carlos Carpena-Torres, Fernando Huete-Toral, Carmen Alvarez-Lorenzo & Gonzalo Carracedo. (2022) Melatonin-Eluting Contact Lenses Effect on Tear Volume: In Vitro and In Vivo Experiments. Pharmaceutics 14:5, pages 1019.
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Victoria Eugenia Lledó, Hanan Awad Alkozi, Juan Sánchez-Naves, Miguel Angel Fernandez-Torres & Ana Guzman-Aranguez. (2022) Melatonin counteracts oxidative damage in lens by regulation of Nrf2 and NLRP3 inflammasome activity. Experimental Eye Research 215, pages 108912.
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Victoria Eugenia Lledó, Hanan Awad Alkozi, Juan Sánchez-Naves, Miguel Angel Fernandez-Torres & Ana Guzman-Aranguez. (2021) Modulation of aqueous humor melatonin levels by yellow-filter and its protective effect on lens. Journal of Photochemistry and Photobiology B: Biology 221, pages 112248.
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Alejandro Martínez-Águila, Alba Martín-Gil, Carlos Carpena-Torres, Cristina Pastrana & Gonzalo Carracedo. (2021) Influence of Circadian Rhythm in the Eye: Significance of Melatonin in Glaucoma. Biomolecules 11:3, pages 340.
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Ede Bodoki, Oliviu Vostinaru, Ovidiu Samoila, Elena Dinte, Andreea E. Bodoki, Sean Swetledge, Carlos E. Astete & Cristina M. Sabliov. (2019) Topical nanodelivery system of lutein for the prevention of selenite-induced cataract. Nanomedicine: Nanotechnology, Biology and Medicine 15:1, pages 188-197.
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Mesut Erdurmuş, Hüseyin Simavlı & Bahri Aydın. 2019. Handbook of Nutrition, Diet, and the Eye. Handbook of Nutrition, Diet, and the Eye 231 244 .
Thilini R. Thrimawithana, Ilva D. Rupenthal, Simon S. Räsch, Julie C. Lim, James D. Morton & Craig R. Bunt. (2018) Drug delivery to the lens for the management of cataracts. Advanced Drug Delivery Reviews 126, pages 185-194.
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Yasaswi Maddirala, Shakila Tobwala, Humeyra Karacal & Nuran Ercal. (2017) Prevention and reversal of selenite-induced cataracts by N-acetylcysteine amide in Wistar rats. BMC Ophthalmology 17:1.
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Almudena Crooke, Fernando Huete‐Toral, Basilio Colligris & Jesús Pintor. (2017) The role and therapeutic potential of melatonin in age‐related ocular diseases. Journal of Pineal Research 63:2.
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Hanan Awad Alkozi, Xiaoyu Wang, Maria J. Perez de Lara & Jesus Pintor. (2017) Presence of melanopsin in human crystalline lens epithelial cells and its role in melatonin synthesis. Experimental Eye Research 154, pages 168-176.
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Mahalingam Sundararajan, Philip A. Thomas, Karuppan Babyshalini & Pitchairaj Geraldine. (2017) Identification of phytoconstituents and in-vitro evaluation of the putative anticataractogenic effect of an ethanolic root extract of Leucas aspera. Biomedicine & Pharmacotherapy 85, pages 87-101.
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Elif Demir, Seyithan Taysi, Behcet Al, Tuncer Demir, Seydi Okumus, Oguzhan Saygili, Edibe Saricicek, Ahmet Dirier, Muslum Akan, Mehmet Tarakcioglu & Cahit Bagci. (2015) The effects of Nigella sativa oil, thymoquinone, propolis, and caffeic acid phenethyl ester on radiation-induced cataract. Wiener klinische Wochenschrift 128:S8, pages 587-595.
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Miguel Caixinha, Joao Amaro, Mario Santos, Fernando Perdigao, Marco Gomes & Jaime Santos. (2016) In-Vivo Automatic Nuclear Cataract Detection and Classification in an Animal Model by Ultrasounds. IEEE Transactions on Biomedical Engineering 63:11, pages 2326-2335.
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Sevsen Kulaksızoglu & Aylin Karalezli. (2016) Aqueous Humour and Serum Levels of Nitric Oxide, Malondialdehyde and Total Antioxidant Status in Patients with Type 2 Diabetes with Proliferative Diabetic Retinopathy and Nondiabetic Senile Cataracts. Canadian Journal of Diabetes 40:2, pages 115-119.
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V. Sreelakshmi & Annie Abraham. (2016) Anthraquinones and flavonoids of Cassia tora leaves ameliorate sodium selenite induced cataractogenesis in neonatal rats. Food & Function 7:2, pages 1087-1095.
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Lepša Žorić, Dijana Miric & Bojana Kisic. 2015. Studies on the Cornea and Lens. Studies on the Cornea and Lens 147 154 .
Maria Giulia Battelli, Andrea Bolognesi & Letizia Polito. (2014) Pathophysiology of circulating xanthine oxidoreductase: New emerging roles for a multi-tasking enzyme. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842:9, pages 1502-1517.
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Mesut Erdurmuş, Hüseyin Simavlı & Bahri Aydın. 2014. Handbook of Nutrition, Diet and the Eye. Handbook of Nutrition, Diet and the Eye 21 28 .
Gamaleldin I. Harisa. (2013) Oxidative Stress and Paraoxonase Activity in Experimental Selenosis: Effects of Betaine Administration. Biological Trace Element Research 152:2, pages 258-266.
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Dijana J. Miric, Bojana B. Kisic, Lepsa D. Zoric, Radoslav V. Mitic, Bratislav M. Miric & Ilija M. Dragojevic. (2013) Xanthine oxidase and lens oxidative stress markers in diabetic and senile cataract patients. Journal of Diabetes and its Complications 27:2, pages 171-176.
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Thirugnanasambandhar Sivasubramania Anitha, Thangaraj Annadurai, Philip A. Thomas & Pitchairaj Geraldine. (2010) Prevention of Selenite-Induced Cataractogenesis by an Ethanolic Extract of Cineraria maritima: An Experimental Evaluation of the Traditional Eye Medication. Biological Trace Element Research 143:1, pages 425-436.
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Pedro Lax, Beatriz Baño Otalora, Gema Esquiva, María de los Ángeles Rol, Juan Antonio Madrid & Nicolás Cuenca. (2010) Circadian dysfunction in P23H rhodopsin transgenic rats: effects of exogenous melatonin. Journal of Pineal Research 50:2, pages 183-191.
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Zuzana Kyselova. (2010) Different experimental approaches in modelling cataractogenesis. Interdisciplinary Toxicology 3:1.
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Lepsa Zoric, Emina Colak, Vladimir Canadanovic, Natalija Kosanovic-Jakovic & Bojana Kisic. (2010) Oxidation stress role in age-related cataractogenesis. Medicinski pregled Medical review 63:7-8, pages 522-526.
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Zuhal Yildirim, Filiz Yildirim, N. Irem Ucgun & Nedret Kilic. (2008) The Evaluation of the Oxidative Stress Parameters in Nondiabetic and Diabetic Senile Cataract Patients. Biological Trace Element Research 128:2, pages 135-143.
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Ei Tae KimJung Hyub Oh. (2009) Effect of Glutathione With Sea Tangle Extract on Prevention of Selenite-Induced Cataract Formation in Rats. Journal of the Korean Ophthalmological Society 50:10, pages 1555.
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Bojana Kisic, Dijana Miric, Lepsa Zoric, Ilija Dragojevic & Aleksandra Stolic. (2009) Role of lipid peroxidation in pathogenesis of senile cataract. Vojnosanitetski pregled Military Medical and Pharmaceutical Journal of Serbia 66:5, pages 371-375.
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Allan F. Wiechmann & Jody A. Summers. (2008) Circadian rhythms in the eye: The physiological significance of melatonin receptors in ocular tissues. Progress in Retinal and Eye Research 27:2, pages 137-160.
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M. Sakthivel, R. Elanchezhian, E. Ramesh, M. Isai, C. Nelson Jesudasan, P.A. Thomas & P. Geraldine. (2008) Prevention of selenite-induced cataractogenesis in Wistar rats by the polyphenol, ellagic acid. Experimental Eye Research 86:2, pages 251-259.
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Adil Kılıç, Şahbettin Selek & Özcan Erel. (2007) Effects Of Erdosteine On Oxidative-Antioxidative Equilibrium And On Cataract Formation In Rat Pups With Selenite-Induced Cataract. Electronic Journal of General Medicine 4:4, pages 149-153.
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