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Journal of Asthma Volume 44, 2007 - Issue 4
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ORIGINAL ARTICLE

The Safety and Efficacy of Zileuton Controlled-Release Tablets as Adjunctive Therapy to Usual Care in the Treatment of Moderate Persistent Asthma: A 6-Month Randomized Controlled Study

Sally Wenzel University of Pittsburgh, Pittsburgh, Pennsylvania
, M.D.,
William Busse University of Wisconsin, Madison, Wisconsin
, M.D.,
William Calhoun UT Medical Branch Galveston, Galveston, Texas
, M.D.,
Reynold Panettieri Jr. University of Pennsylvania, Philadelphia, Pennsylvania
, M.D.,
Mark Peters-Golden University of Michigan, Ann Arbor, Michigan
, M.D.,
Louise Dube Pleiades Consultation, Inc., Scottsdale, Arizona
, PhD.,
Karen Walton-Bowen Critical Therapeutics, Inc., Lexington, Massachusetts
, M.Sc., cSTAT,
Heidy Russell PROMETRIKA, LLC, Cambridge, Massachusetts
, Ph.D. &
Judith Harris PROMETRIKA, LLC, Cambridge, Massachusetts
, B.Sc. (Hons) show all
Pages 305-310 | Published online: 02 Jul 2009

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Freddi I Zuniga, Danmy Loi, Kah Hiing John Ling & Diane D-S Tang-Liu. (2012) Idiosyncratic reactions and metabolism of sulfur-containing drugs. Expert Opinion on Drug Metabolism & Toxicology 8:4, pages 467-485.
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Articles from other publishers (23)

Francesca Citron, Luigi Perelli, Angela K. Deem, Giannicola Genovese & Andrea Viale. (2020) Leukotrienes, a potential target for Covid-19. Prostaglandins, Leukotrienes and Essential Fatty Acids 161, pages 102174.
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P. Thalanayar Muthukrishnan, M. Nouraie, A. Parikh & F. Holguin. (2019) Zileuton use and phenotypic features in asthma. Pulmonary Pharmacology & Therapeutics, pages 101872.
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Mohammad Reza Baezzat, Fatemeh Banavand & Farshid Fasihi. (2018) Highly sensitive determination of zileuton using TiO2 nanoparticles and the ionic liquid 1-hexylpyridinium hexafluorophosphate nanocomposite sensor. Ionics 25:4, pages 1835-1844.
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Sung-Dong Kim & Kyu-Sup Cho. (2018) Samter’s Triad: State of the Art. Clinical and Experimental Otorhinolaryngology 11:2, pages 71-80.
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Nathaniel C. Gilbert, David B. Neau & Marcia E. Newcomer. 2018. Marine Enzymes and Specialized Metabolism - Part B. Marine Enzymes and Specialized Metabolism - Part B 33 49 .
Joshua M. Levy, Luke Rudmik, Anju T. Peters, Sarah K. Wise, Brian W. Rotenberg & Timothy L. Smith. (2016) Contemporary management of chronic rhinosinusitis with nasal polyposis in aspirin-exacerbated respiratory disease: an evidence-based review with recommendations. International Forum of Allergy & Rhinology 6:12, pages 1273-1283.
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A Dahlin, A Litonjua, C G Irvin, S P Peters, J J Lima, M Kubo, M Tamari & K G Tantisira. (2015) Genome-wide association study of leukotriene modifier response in asthma. The Pharmacogenomics Journal 16:2, pages 151-157.
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Kathleen M. Buchheit & Tanya M. Laidlaw. (2016) Update on the Management of Aspirin-Exacerbated Respiratory Disease. Allergy, Asthma & Immunology Research 8:4, pages 298.
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Rahul Magazine, HameedAboobackar Shahul, Bharti Chogtu & Asha Kamath. (2016) Comparison of oral montelukast with oral zileuton in acute asthma: A randomized, double-blind, placebo-controlled study. Lung India 33:3, pages 281.
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Njira Lugogo, Loretta G. Que, Daniel L. Gilstrap & Monica Kraft. 2016. Murray and Nadel's Textbook of Respiratory Medicine. Murray and Nadel's Textbook of Respiratory Medicine 731 750.e7 .
. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 564 566 .
Timothy E. Albertson, Mark E. Sutter & Andrew L. Chan. (2014) The Acute Management of Asthma. Clinical Reviews in Allergy & Immunology 48:1, pages 114-125.
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T. E. Albertson, M. Schivo, N. Gidwani, N. J. Kenyon, M. E. Sutter, A. L. Chan & S. Louie. (2013) Pharmacotherapy of Critical Asthma Syndrome: Current and Emerging Therapies. Clinical Reviews in Allergy & Immunology 48:1, pages 7-30.
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Phillip Pian, Edward Labovitz, Keith Hoffman, Claudia F. Clavijo, Rachael Rzasa Lynn, Jeffrey L. Galinkin, Alexander A. Vinks, Punam Malik & Uwe Christians. (2013) Quantification of the 5-lipoxygenase inhibitor zileuton in human plasma using high performance liquid chromatography–tandem mass spectrometry. Journal of Chromatography B 937, pages 79-83.
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Amit H. Kubavat, Narendra Khippal, Sandeep Tak, Puneet Rijhwani, Salil Bhargava, Tushar Patel, Nalin Shah, Rakeshkumar R. Kshatriya & Ravindra Mittal. (2013) A Randomized, Comparative, Multicentric Clinical Trial to Assess the Efficacy and Safety of Zileuton Extended-Release Tablets With Montelukast Sodium Tablets in Patients Suffering From Chronic Persistent Asthma. American Journal of Therapeutics 20:2, pages 154-162.
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Rachel G. Moebus & Joseph K. Han. (2012) Immunomodulatory Treatments for Aspirin Exacerbated Respiratory Disease. American Journal of Rhinology & Allergy 26:2, pages 134-140.
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Anne Fuhlbrigge, David Peden, Andrea J. Apter, Homer A. Boushey, Carlos A. CamargoJr.Jr., James Gern, Peter W. Heymann, Fernando D. Martinez, David Mauger, William G. Teague & Carol Blaisdell. (2012) Asthma outcomes: Exacerbations. Journal of Allergy and Clinical Immunology 129:3, pages S34-S48.
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Katsuhide Okunishi & Marc Peters-Golden. (2011) Leukotrienes and airway inflammation. Biochimica et Biophysica Acta (BBA) - General Subjects 1810:11, pages 1096-1102.
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Navin L. Rao, Jason P. Riley, Homayon Banie, Xiaohua Xue, Binggang Sun, Shelby Crawford, Katherine A. Lundeen, Fuqu Yu, Lars Karlsson, Anne M. Fourie & Paul J. Dunford. (2010) Leukotriene A 4 Hydrolase Inhibition Attenuates Allergic Airway Inflammation and Hyperresponsiveness . American Journal of Respiratory and Critical Care Medicine 181:9, pages 899-907.
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Keir E. Lewis & Gwyneth A. Davies. 2010. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions 311 331 .
Njira Lugogo, Loretta G. Que, Daniel Fertel & Monica Kraft. 2010. Murray and Nadel's Textbook of Respiratory Medicine. Murray and Nadel's Textbook of Respiratory Medicine 883 918 .
Kian Fan Chung & Peter J. Barnes. 2009. Asthma and COPD. Asthma and COPD 655 662 .
Ronald Balkissoon. (2008) Asthma Overview. Primary Care: Clinics in Office Practice 35:1, pages 41-60.
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