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ORIGINAL ARTICLE

Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab

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Pages 196-201 | Received 15 Jul 2005, Published online: 08 Jul 2009

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Yan-Jie Cheng, Fan Fan, Zhong Zhang & Hai-jun Zhang. (2023) Lipid metabolism in malignant tumor brain metastasis: reprogramming and therapeutic potential. Expert Opinion on Therapeutic Targets 27:9, pages 861-878.
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Alexandra S Zimmer, Seth M Steinberg, Dee Dee Smart, Mark R Gilbert, Terri S Armstrong, Eric Burton, Nicole Houston, Nadia Biassou, Brunilde Gril, Priscilla K Brastianos, Scott Carter, David Lyden, Stanley Lipkowitz & Patricia S Steeg. (2020) Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases. Future Oncology 16:14, pages 899-909.
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A Mukherjee, AS Dhadda, M Shehata & Stephen Chan. (2007) Lapatinib: a tyrosine kinase inhibitor with a clinical role in breast cancer. Expert Opinion on Pharmacotherapy 8:13, pages 2189-2204.
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Domenico Errante, Daniele Bernardi, Antonio Bianco & Luigi Salvagno. (2007) Comment on: Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab. Acta Oncologica 46:4, pages 565-566.
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Franziska M. Ippen, Elisa Aquilanti, Helen D’Couto, Julia Grosch & Priscilla K. Brastianos. 2020. Central Nervous System Metastases. Central Nervous System Metastases 43 58 .
Linda Dirven & Martin J. B. Taphoorn. 2020. Central Nervous System Metastases. Central Nervous System Metastases 3 14 .
Mariko Asaoka, Kazutaka Narui, Nobuyasu Suganuma, Takashi Chishima, Akimitsu Yamada, Sadatoshi Sugae, Saori Kawai, Natsuki Uenaka, Saeko Teraoka, Kana Miyahara, Takahiko Kawate, Eichi Sato, Toshitaka Nagao, Yuka Matsubara, Shipra Gandhi, Kazuaki Takabe & Takashi Ishikawa. (2019) Clinical and pathological predictors of recurrence in breast cancer patients achieving pathological complete response to neoadjuvant chemotherapy. European Journal of Surgical Oncology 45:12, pages 2289-2294.
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Tan To Cheung, Kenneth SH Chok, Albert CY Chan, Simon HY Tsang, Wing Chiu Dai, Thomas CC Yau, Ava Kwong & Chung Mau Lo. (2019) Survival analysis of breast cancer liver metastasis treated by hepatectomy: A propensity score analysis for Chinese women in Hong Kong. Hepatobiliary & Pancreatic Diseases International 18:5, pages 452-457.
Crossref
Anders W. Erickson & Sunit Das. (2019) The Impact of Targeted Therapy on Intracranial Metastatic Disease Incidence and Survival. Frontiers in Oncology 9.
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Kevin Armstrong, Jennifer Ward, Mary Dunne, Luke Rock, Jennifer Westrup, Christopher R. Mascott, Pierre Thirion & Alina Mihaela Mihai. (2019) Linac-Based Radiosurgery for Patients With Brain Oligometastases From a Breast Primary, in the Trastuzumab Era-Impact of Tumor Phenotype and Prescribed SRS Dose. Frontiers in Oncology 9.
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Joanne W Chiu, Roland Leung, Vikki Tang, Wai Yin Cheuk, Jessica Lo, Gin Wai Kwok, Hilda Wong, Dacita Suen, Polly Cheung, Ting Ting Wong, Thomas Yau & Ava Kwong. (2019) Changing pattern of recurrences in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy in the era of dual anti-HER2 therapy. Postgraduate Medical Journal 95:1121, pages 155-161.
Crossref
Haiyang Su, Zhenyang Lin, Weicheng Peng & Zhiqiang Hu. (2018) Identification of potential biomarkers of lung adenocarcinoma brain metastases via microarray analysis of cDNA expression profiles. Oncology Letters.
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I. Witzel, E. Laakmann, R. Weide, T. Neunhöffer, T.-J. Park-Simon, M. Schmidt, P.A. Fasching, T. Hesse, A. Polasik, S. Mohrmann, F. Würschmidt, C. Schem, C. Bechtner, R. Würstlein, T. Fehm, V. Möbus, N. Burchardi, S. Loibl & V. Müller. (2018) Treatment and outcomes of patients in the Brain Metastases in Breast Cancer Network Registry. European Journal of Cancer 102, pages 1-9.
Crossref
David M. Routman, Shelly X. Bian, Kevin Diao, Jonathan L. Liu, Cheng Yu, Jason Ye, Gabriel Zada & Eric L. Chang. (2018) The growing importance of lesion volume as a prognostic factor in patients with multiple brain metastases treated with stereotactic radiosurgery. Cancer Medicine 7:3, pages 757-764.
Crossref
Lokesh Dalasanur Nagaprashantha, Ramesh Adhikari, Jyotsana Singhal, Shireen Chikara, Sanjay Awasthi, David Horne & Sharad S. Singhal. (2017) Translational opportunities for broad‐spectrum natural phytochemicals and targeted agent combinations in breast cancer. International Journal of Cancer 142:4, pages 658-670.
Crossref
Adel Samson, Karen J. ScottDavid Taggart, Emma J. WestErica Wilson, Gerard J. Nuovo, Simon Thomson, Robert CornsRyan K. Mathew, Martin J. FullerTimothy J. KottkeJill M. ThompsonElizabeth J. Ilett, Julia V. Cockle, Philip van HilleGnanamurthy SivakumarEuan S. PolsonSamantha J. Turnbull, Elizabeth S. AppletonGemma MignecoAilsa S. Rose, Matthew C. CoffeyDeborah A. Beirne, Fiona J. CollinsonChristy Ralph, D. Alan Anthoney, Christopher J. TwelvesAndrew J. FurnessSergio A. Quezada, Heiko Wurdak, Fiona Errington-Mais, Hardev PandhaKevin J. HarringtonPeter J. Selby, Richard G. VileStephen D. Griffin, Lucy F. Stead, Susan C. Short & Alan A. Melcher. (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine 10:422.
Crossref
Herbert H. Engelhard, Gregory D. Arnone, Ankit I. Mehta & Martin K. Nicholas. 2018. Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy. Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy 113 125 .
Joo Yeon Nam & Barbara J. O’Brien. (2017) Current chemotherapeutic regimens for brain metastases treatment. Clinical & Experimental Metastasis 34:6-7, pages 391-399.
Crossref
Arnaldo Marín, Alex Renner, Laura Itriago & Manuel Álvarez. (2017) METÁSTASIS CEREBRALES: UNA MIRADA BIOLÓGICA Y CLÍNICA. Revista Médica Clínica Las Condes 28:3, pages 437-449.
Crossref
Ibiayi Dagogo-Jack, Corey M. Gill, Daniel P. Cahill, Sandro Santagata & Priscilla K. Brastianos. (2017) Treatment of brain metastases in the modern genomic era. Pharmacology & Therapeutics 170, pages 64-72.
Crossref
Vivien Chan, Arjun Sahgal, Peter Egeto, Tom Schweizer & Sunit Das. (2016) Incidence of seizure in adult patients with intracranial metastatic disease. Journal of Neuro-Oncology 131:3, pages 619-624.
Crossref
Isabell Witzel, Leticia Oliveira-Ferrer, Klaus Pantel, Volkmar Müller & Harriet Wikman. (2016) Breast cancer brain metastases: biology and new clinical perspectives. Breast Cancer Research 18:1.
Crossref
Thiele Kobus, Ioannis K. Zervantonakis, Yongzhi Zhang & Nathan J. McDannold. (2016) Growth inhibition in a brain metastasis model by antibody delivery using focused ultrasound-mediated blood-brain barrier disruption. Journal of Controlled Release 238, pages 281-288.
Crossref
Ji Yun Lee, Kyunghee Park, Eunjin Lee, TaeJin Ahn, Hae Hyun Jung, Sung Hee Lim, Mineui Hong, In-Gu Do, Eun Yoon Cho, Duk-Hwan Kim, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im & Yeon Hee Park. (2016) Gene Expression Profiling of Breast Cancer Brain Metastasis. Scientific Reports 6:1.
Crossref
William Jacot, Elvire Pons, Jean-Sébastien Frenel, Séverine Guiu, Christelle Levy, Pierre Etienne Heudel, Thomas Bachelot, Véronique D’Hondt, Amélie Darlix, Nelly Firmin, Gilles Romieu, Simon Thezenas & Florence Dalenc. (2016) Efficacy and safety of trastuzumab emtansine (T-DM1) in patients with HER2-positive breast cancer with brain metastases. Breast Cancer Research and Treatment 157:2, pages 307-318.
Crossref
Renata Duchnowska & Jacek Jassem. 2016. Brain Metastases from Primary Tumors, Volume 3. Brain Metastases from Primary Tumors, Volume 3 225 236 .
Kenichi Inoue, Katsumasa Kuroi, Satoru Shimizu, Yoshiaki Rai, Kenjiro Aogi, Norikazu Masuda, Takahiro Nakayama, Hiroji Iwata, Yuichiro Nishimura, Alison Armour & Yasutsuna Sasaki. (2015) Safety, pharmacokinetics and efficacy findings in an open-label, single-arm study of weekly paclitaxel plus lapatinib as first-line therapy for Japanese women with HER2-positive metastatic breast cancer. International Journal of Clinical Oncology 20:6, pages 1102-1109.
Crossref
Muhammet Ali Kaplan, Hamza Ertugrul, Ugur Firat, Mehmet Kucukoner, Ali İnal, Zuhat Urakci, Zafer Pekkolay & Abdurrahman Isikdogan. (2014) Brain metastases in HER2-positive metastatic breast cancer patients who received chemotherapy with or without trastuzumab. Breast Cancer 22:5, pages 503-509.
Crossref
Xavier PivotAlexey ManikhasBogdan ŻurawskiEwa ChmielowskaBoguslawa KaraszewskaRozenn AllertonStephen ChanAlessandra FabiPaolo BidoliStefania GoriEva CiruelosMagdolna DankLajos HornyakSara MargolinArnd NuschRoma ParikhFareha NagiMichelle DeSilvioSergio SantillanaRamona F. SwabyVladimir Semiglazov. (2015) CEREBEL (EGF111438): A Phase III, Randomized, Open-Label Study of Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer. Journal of Clinical Oncology 33:14, pages 1564-1573.
Crossref
Akbar Hedayatizadeh-Omran, Alireza Rafiei, Reza Alizadeh-Navaei, Mohsen Tehrani, Reza Valadan, Kambiz Moradzadeh, Mohammad Panbechi & Seyed Mehdi Taghavi. (2015) Role of HER2 in Brain Metastasis of Breast Cancer: a Systematic Review and Meta-Analysis. Asian Pacific Journal of Cancer Prevention 16:4, pages 1431-1434.
Crossref
Richard De Boer, Jane Beith, Jacquie Chirgwin, Sue Chua, Maree Colosimo, Prudence Francis, Michael Green, Ken Pittman, Michelle White, Nicholas Wilcken, Nicholas Zdenkowski & Richard Bell. (2014) Systemic treatment of HER2+ metastatic breast cancer: Clinical conundrums and future perspectives. Asia-Pacific Journal of Clinical Oncology 10, pages 15-25.
Crossref
Jaclyn J. Renfrow & Glenn J. Lesser. (2013) Molecular Subtyping of Brain Metastases and Implications for Therapy. Current Treatment Options in Oncology 14:4, pages 514-527.
Crossref
Nina Martinez, Adrienne Boire & Lisa DeAngelis. (2013) Molecular Interactions in the Development of Brain Metastases. International Journal of Molecular Sciences 14:8, pages 17157-17167.
Crossref
Ines Vaz-Luis, Davinia Seah, Erin M. Olson, Nikhil Wagle, Otto Metzger-Filho, Jessica Sohl, Georgia Litsas, Harold J. Burstein, Ian E. Krop, Eric P. Winer & Nancy U. Lin. (2013) Clinicopathological Features Among Patients With Advanced Human Epidermal Growth Factor–2-Positive Breast Cancer With Prolonged Clinical Benefit to First-Line Trastuzumab-Based Therapy: A Retrospective Cohort Study. Clinical Breast Cancer 13:4, pages 254-263.
Crossref
Hiroji Iwata, Masaru Narabayashi, Yoshinori Ito, Shigehira Saji, Yasuhiro Fujiwara, Shigeyuki Usami, Koichi Katsura & Yasutsuna Sasaki. (2012) A phase II study of lapatinib for brain metastases in patients with HER2-overexpressing breast cancer following trastuzumab based systemic therapy and cranial radiotherapy: subset analysis of Japanese patients. International Journal of Clinical Oncology 18:4, pages 621-628.
Crossref
Ankit I. Mehta, Adam M. Brufsky & John H. Sampson. (2013) Therapeutic approaches for HER2-positive brain metastases: Circumventing the blood–brain barrier. Cancer Treatment Reviews 39:3, pages 261-269.
Crossref
Shoji Yomo, Motohiro Hayashi & Narisumi Cho. (2013) Impacts of HER2-overexpression and molecular targeting therapy on the efficacy of stereotactic radiosurgery for brain metastases from breast cancer. Journal of Neuro-Oncology 112:2, pages 199-207.
Crossref
Rupert Bartsch, Anna S. Berghoff & Matthias Preusser. (2012) Optimal Management of Brain Metastases from Breast Cancer. CNS Drugs 27:2, pages 121-134.
Crossref
Mustafa Oktay Tarhan, Lutfiye Demir, Isil Somali, Seyran Yigit, Cigdem Erten, Ahmet Alacacioglu, Hulya Ellidokuz, Ozgur Seseogullari, Yuksel Kucukzeybek, Alper Can, Ahmet Dirican, Vedat Bayoglu & Murat Akyol. (2012) The clinicopathological evaluation of the breast cancer patients with brain metastases: predictors of survival. Clinical & Experimental Metastasis 30:2, pages 201-213.
Crossref
A. Jo Chien & Hope S. Rugo. (2012) Emerging treatment options for the management of brain metastases in patients with HER2-positive metastatic breast cancer. Breast Cancer Research and Treatment 137:1, pages 1-12.
Crossref
Yvonne Kienast. 2013. Experimental Metastasis: Modeling and Analysis. Experimental Metastasis: Modeling and Analysis 93 115 .
Mi-Ran Choi, Rizia Bardhan, Katie J. Stanton-Maxey, Sunil Badve, Harikrishna Nakshatri, Keith M. Stantz, Ning Cao, Naomi J. Halas & Susan E. Clare. (2012) Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse. Cancer Nanotechnology 3:1-6, pages 47-54.
Crossref
Riccardo Soffietti, Elisa Trevisan & Roberta Rudà. (2012) Targeted therapy in brain metastasis. Current Opinion in Oncology 24:6, pages 679-686.
Crossref
Y S Yap, G H Cornelio, B C R Devi, C Khorprasert, S B Kim, T Y Kim, S C Lee, Y H Park, J H Sohn, N Sutandyo, D W Y Wong, M Kobayashi, S H Landis, E M Yeoh, H Moon & J Ro. (2012) Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival. British Journal of Cancer 107:7, pages 1075-1082.
Crossref
Zhiyuan Xu, Nicholas F. Marko, Sam T. Chao, Lilyana Angelov, Michael A. Vogelbaum, John H. Suh, Gene H. Barnett & Robert J. Weil. (2012) Relationship Between HER2 Status and Prognosis in Women With Brain Metastases From Breast Cancer. International Journal of Radiation Oncology*Biology*Physics 82:5, pages e739-e747.
Crossref
Rachel A. Freedman & Carey K. Anders. (2011) Treatment of Breast Cancer Brain Metastases. Current Breast Cancer Reports 4:1, pages 1-9.
Crossref
Joseph A. Bovi & Julia White. (2011) Radiation Therapy in the Prevention of Brain Metastases. Current Oncology Reports 14:1, pages 55-62.
Crossref
Lakshmi Nayak, Eudocia Quant Lee & Patrick Y. Wen. (2011) Epidemiology of Brain Metastases. Current Oncology Reports 14:1, pages 48-54.
Crossref
Mark D. Danese, Karla Lindquist, Justin Doan, Deepa Lalla, Melissa Brammer & Robert I. Griffiths. (2012) Effect of Central Nervous System Metastases on Treatment Discontinuation and Survival in Older Women Receiving Trastuzumab for Metastatic Breast Cancer. Journal of Cancer Epidemiology 2012, pages 1-9.
Crossref
R Bartsch, A Berghoff, U Pluschnig, Z Bago-Horvath, P Dubsky, A Rottenfusser, C DeVries, M Rudas, F Fitzal, K Dieckmann, R M Mader, M Gnant, C C Zielinski & G G Steger. (2011) Impact of anti-HER2 therapy on overall survival in HER2-overexpressing breast cancer patients with brain metastases. British Journal of Cancer 106:1, pages 25-31.
Crossref
Farheen Arshad, Lili Wang, Christopher Sy, Shalom Avraham & Hava Karsenty Avraham. (2011) Blood-Brain Barrier Integrity and Breast Cancer Metastasis to the Brain. Pathology Research International 2011, pages 1-12.
Crossref
Dionysis Papadatos-Pastos & Udai Banerji. (2011) Revisiting the role of molecular targeted therapies in patients with brain metastases. Journal of Neuro-Oncology 105:3, pages 467-474.
Crossref
Hilda Wong, Roland Leung, Ava KwongJoanne Chiu, Raymond Liang, Charles Swanton & Thomas Yau. (2011) Integrating Molecular Mechanisms and Clinical Evidence in the Management of Trastuzumab Resistant or Refractory HER-2+ Metastatic Breast Cancer. The Oncologist 16:11, pages 1535-1546.
Crossref
Antonino Musolino, Laura Ciccolallo, Michele Panebianco, Elisa Fontana, Daniele Zanoni, Cecilia Bozzetti, Maria Michiara, Enrico Maria Silini & Andrea Ardizzoni. (2010) Multifactorial central nervous system recurrence susceptibility in patients with HER2‐positive breast cancer. Cancer 117:9, pages 1837-1846.
Crossref
Isabell Witzel, Eva Johanna Kantelhardt, Karin Milde-Langosch, Maike Ihnen, Julia Zeitz, Nadia Harbeck, Fritz Jänicke & Volkmar Müller. (2011) Management of Patients with Brain Metastases Receiving Trastuzumab Treatment for Metastatic Breast Cancer. Onkologie 34:6, pages 304-308.
Crossref
S. Dawood, N.T. Ueno, V. Valero, E. Andreopoulou, L. Hsu, J. Lara, W. Woodward, T.A. Buchholz, G.N. Hortobagyi & M. Cristofanilli. (2010) Incidence of and survival following brain metastases among women with inflammatory breast cancer. Annals of Oncology 21:12, pages 2348-2355.
Crossref
Anna Niwińska, Małgorzata Tacikowska & Magdalena Murawska. (2010) The Effect of Early Detection of Occult Brain Metastases in HER2-Positive Breast Cancer Patients on Survival and Cause of Death. International Journal of Radiation Oncology*Biology*Physics 77:4, pages 1134-1139.
Crossref
Angélique P. J. M. Braen, Josée Perron, Pierre Tellier, Anthony R. Catala, Gerry Kolaitis & Wanping Geng. (2010) A 4-Week Intrathecal Toxicity and Pharmacokinetic Study With Trastuzumab in Cynomolgus Monkeys. International Journal of Toxicology 29:3, pages 259-267.
Crossref
A. Niwińska, M. Murawska & K. Pogoda. (2010) Breast cancer brain metastases: differences in survival depending on biological subtype, RPA RTOG prognostic class and systemic treatment after whole-brain radiotherapy (WBRT). Annals of Oncology 21:5, pages 942-948.
Crossref
T. Pieńkowski & C.C. Zielinski. (2010) Trastuzumab treatment in patients with breast cancer and metastatic CNS disease. Annals of Oncology 21:5, pages 917-924.
Crossref
Olivier GraesslinBassam S. AbdulkarimCharles CoutantFlorence HuguetZsolt GabosLimin HsuOlivier MarpeauSerge UzanLajos PusztaiEric A. StromGabriel N. HortobagyiRoman RouzierNuhad K. Ibrahim. (2010) Nomogram to Predict Subsequent Brain Metastasis in Patients With Metastatic Breast Cancer. Journal of Clinical Oncology 28:12, pages 2032-2037.
Crossref
J-S FrenelE BourboulouxD Berton-RigaudS Sadot-LebouvierA ZanettiM Campone. (2009) Lapatinib in Metastatic Breast Cancer. Women's Health 5:6, pages 603-612.
Crossref
Brian Leyland-Jones. (2009) Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Central Nervous System Metastases. Journal of Clinical Oncology 27:31, pages 5278-5286.
Crossref
Renata Duchnowska, Rafał Dziadziuszko, Bogumiła Czartoryska-Arłukowicz, Barbara Radecka, Barbara Szostakiewicz, Katarzyna Sosińska-Mielcarek, Agnieszka Karpińska, Elżbieta Starosławska, Tomasz Kubiatowski & Cezary Szczylik. (2009) Risk factors for brain relapse in HER2-positive metastatic breast cancer patients. Breast Cancer Research and Treatment 117:2, pages 297-303.
Crossref
Riccardo Soffietti, Wallace Akerley, Randy L. Jensen, Joachim Bischoff & Anne Constanze Regierer. (2009) The Role of Intra-cerebrospinal Fluid Treatment and Prophylaxis in Patients With Solid Tumors. Seminars in Oncology 36, pages S55-S68.
Crossref
M. Untch & C. Jackisch. (2009) Behandlung der Patientinnen mit HER2- (ErbB2-) positivem MammakarzinomTreatment of patients with HER2 (erbB2) positive breast cancer. Der Onkologe 15:8, pages 811-826.
Crossref
Peter S Hall, Jaishree Bhosle & David A Cameron. (2009) Lapatinib in the management of breast cancer. Therapy 6:4, pages 553-568.
Crossref
Y H Park, M J Park, S H Ji, S Y Yi, D H Lim, D H Nam, J-I Lee, W Park, D H Choi, S J Huh, J S Ahn, W K Kang, K Park & Y-H Im. (2009) Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients. British Journal of Cancer 100:6, pages 894-900.
Crossref
Fleur Huang, Munir Alrefae, Adrian Langleben & David Roberge. (2009) Prophylactic Cranial Irradiation in Advanced Breast Cancer: A Case for Caution. International Journal of Radiation Oncology*Biology*Physics 73:3, pages 752-758.
Crossref
Nancy U. Lin, Véronique Diéras, Devchand Paul, Dominique Lossignol, Christos Christodoulou, Hans-Joachim Stemmler, Henri Roché, Minetta C. Liu, Richard Greil, Eva Ciruelos, Sibylle Loibl, Stefania Gori, Andrew Wardley, Denise Yardley, Adam Brufsky, Joanne L. Blum, Stephen D. Rubin, Bernie Dharan, Klaudia Steplewski, Denise Zembryki, Cristina Oliva, Debasish Roychowdhury, Paolo Paoletti & Eric P. Winer. (2009) Multicenter Phase II Study of Lapatinib in Patients with Brain Metastases from HER2-Positive Breast Cancer. Clinical Cancer Research 15:4, pages 1452-1459.
Crossref
Makiko Ono, Masashi Ando, Mayu Yunokawa, Eriko Nakano, Kan Yonemori, Koji Matsumoto, Tsutomu Kouno, Chikako Shimizu, Kenji Tamura, Noriyuki Katsumata & Yasuhiro Fujiwara. (2009) Brain metastases in patients who receive trastuzumab-containing chemotherapy for HER2-overexpressing metastatic breast cancer. International Journal of Clinical Oncology 14:1, pages 48-52.
Crossref
David N. ChurchChris G.A. Price. (2009) A Review of Trastuzumab-Based Therapy in Patients with HER2-positive Metastatic Breast Cancer. Clinical Medicine. Therapeutics 1, pages CMT.S35.
Crossref
Michelle E Melisko, Michael Glantz & Hope S Rugo. (2008) New challenges and opportunities in the management of brain metastases in patients with ErbB2-positive metastatic breast cancer. Nature Clinical Practice Oncology 6:1, pages 25-33.
Crossref
David A Cameron & Steven Stein. (2008) Drug Insight: intracellular inhibitors of HER2—clinical development of lapatinib in breast cancer. Nature Clinical Practice Oncology 5:9, pages 512-520.
Crossref
Robert M. Sharkey & David M. Goldenberg. (2008) Use of antibodies and immunoconjugates for the therapy of more accessible cancers. Advanced Drug Delivery Reviews 60:12, pages 1407-1420.
Crossref
Hans-Joachim Stemmler & Volker Heinemann. (2008) Central Nervous System Metastases in HER-2–Overexpressing Metastatic Breast Cancer: A Treatment Challenge. The Oncologist 13:7, pages 739-750.
Crossref
Issa J. Dahabreh, Helen Linardou, Fotios Siannis, George Fountzilas & Samuel Murray. (2008) Trastuzumab in the Adjuvant Treatment of Early-Stage Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. The Oncologist 13:6, pages 620-630.
Crossref
David N. Church, Ramayana Modgil, Sam Guglani, Amit Bahl, Kirsten Hopkins, Jeremy P. Braybrooke, Peter Blair & Chris G. A. Price. (2008) Extended Survival in Women With Brain Metastases From HER2 Overexpressing Breast Cancer. American Journal of Clinical Oncology 31:3, pages 250-254.
Crossref
April F. Eichler, Irene Kuter, Paula Ryan, Lidia Schapira, Jerry Younger & John W. Henson. (2008) Survival in patients with brain metastases from breast cancer. Cancer 112:11, pages 2359-2367.
Crossref
Gloria Roldán, James Scott, David George, Ian Parney, Jacob Easaw, Gregory Cairncross, Peter Forsyth & Elizabeth Yan. (2014) Leptomeningeal Disease from Oligodendroglioma: Clinical and Molecular Analysis. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 35:2, pages 204-209.
Crossref
Neil Spector. (2008) Treatment of Metastatic ErbB2-Positive Breast Cancer: Options After Progression on Trastuzumab. Clinical Breast Cancer 8, pages S94-S99.
Crossref
Pierre Fumoleau. (2008) Future options in the treatment of ErbB2 (HER2)-positive breast cancer. European Journal of Cancer Supplements 6:5, pages 25-31.
Crossref
Christian Jackisch. (2008) Challenges in the treatment of ErbB2 (HER2)-positive breast cancer. European Journal of Cancer Supplements 6:5, pages 7-14.
Crossref
Elise M. Pelletier, Boyung Shim, Seth Goodman & Mayur M. Amonkar. (2007) Epidemiology and economic burden of brain metastases among patients with primary breast cancer: results from a US claims data analysis. Breast Cancer Research and Treatment 108:2, pages 297-305.
Crossref
U. Liebeskind, F. Fitzal, R. Jakesz, W. DÖller & C. Ure. 2008. Chirurgische Onkologie. Chirurgische Onkologie 95 121 .
Xiaoyun Cheng & Mien-Chie Hung. (2007) Breast cancer brain metastases. Cancer and Metastasis Reviews 26:3-4, pages 635-643.
Crossref
Stefania Gori, Simonetta Rimondini, Verena De Angelis, Mariantonietta Colozza, Giancarlo Bisagni, Gabriella Moretti, Angelo Sidoni, Carlo Basurto, Cynthia Aristei, Paola Anastasi & Lucio Crinò. (2007) Central Nervous System Metastases in HER-2–Positive Metastatic Breast Cancer Patients Treated with Trastuzumab: Incidence, Survival, and Risk Factors. The Oncologist 12:7, pages 766-773.
Crossref
V. Adamo, T. Franchina, B. Adamo, G. Ferraro, R. Rossello, M. Maugeri Saccà, C. Scibilia, M.R. Valerio & A. Russo. (2007) Safety and activity of trastuzumab-containing therapies for the treatment of metastatic breast cancer: our long-term clinical experience (GOIM study). Annals of Oncology 18, pages vi11-vi15.
Crossref
Teri D. Nguyen & Lauren E. Abrey. (2007) Brain Metastases: Old Problem, New Strategies. Hematology/Oncology Clinics of North America 21:2, pages 369-388.
Crossref
Nancy U. Lin & Eric P. Winer. (2007) Brain Metastases: The HER2 Paradigm. Clinical Cancer Research 13:6, pages 1648-1655.
Crossref
Adam I. Riker, SuHu Liu, Mona Hagmaier, Matthew J. D. D'lessio & Charles E. Cox. 2007. Metastasis of Breast Cancer. Metastasis of Breast Cancer 355 372 .

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