Citations (38)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Chen Peng, Xueying Li, He Huang, Tingzhi Liu, Zhao Wang, Xiaojie Fang, Huangming Hong, Fangfang Li, Quanguang Ren, Shu Liu, Ying Tian & Tongyu Lin. (2020) A prospective, crossover randomized trial of the optimal timing for leucovorin rescue after high-dose methotrexate management in adult non-Hodgkin’s lymphoma patients. Leukemia & Lymphoma 61:8, pages 1842-1849.
Read now
Read now
Boris Bienvenu, Achille Aouba, Jacques-Eric Gottenberg & Celine Verstuyft. (2017) Single-center, single-dose, open-label, randomized, two-period crossover study on the bioavailability of methotrexate administered using a novel prefilled, needle-free delivery system. Current Medical Research and Opinion 33:4, pages 605-611.
Read now
Read now
Betty S. Chan, Andrew H. Dawson & Nicholas A. Buckley. (2017) What can clinicians learn from therapeutic studies about the treatment of acute oral methotrexate poisoning?. Clinical Toxicology 55:2, pages 88-96.
Read now
Read now
M. Joerger, A. D. R. Huitema, G. Illerhaus & A. J. M. Ferreri. (2012) Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma. Leukemia & Lymphoma 53:10, pages 1867-1875.
Read now
Read now
Articles from other publishers (34)
Marc Parrilla, Usanee Detamornrat, Juan Domínguez-Robles, Sensu Tunca, Ryan F. Donnelly & Karolien De Wael. (2023) Wearable Microneedle-Based Array Patches for Continuous Electrochemical Monitoring and Drug Delivery: Toward a Closed-Loop System for Methotrexate Treatment. ACS Sensors 8:11, pages 4161-4170.
Crossref
Crossref
Iswari Davan, Sharida Fakurazi, Ekram Alias, Nurul ‘Izzah Ibrahim, Ng Min Hwei & Haniza Hassan. (2023) Astaxanthin as a Potent Antioxidant for Promoting Bone Health: An Up-to-Date Review. Antioxidants 12:7, pages 1480.
Crossref
Crossref
Steven Bialick, Leticia Campoverde, Jesus Antonio Ocejo Gallegos, Priscila Barreto-Coelho, Aleksandra Watson, Kshitij Arora, Andres Perez, Esdras Lopez, Shree Venkat, Andrew E. Rosenberg, Brooke Crawford, Emily Jonczak, Jonathan Trent, Aditi Dhir & Gina D’Amato. (2023) Osteogenic Sarcoma of the Head and Neck: Is Chemotherapy Needed?. Current Treatment Options in Oncology 24:5, pages 528-541.
Crossref
Crossref
Chuanchao Du, Xiaoguang Liu, Zhongjun Liu & Feng Wei. (2023) The Dilemma of Balance between Benefits and Losses for Chondromyxoid Fibroma-like Osteosarcoma in Thoracic Spine with Azygos Tumor Thrombosis: A Case Report. Medicina 59:4, pages 792.
Crossref
Crossref
Manuel Ibarra, Ryan Combs, Zachary L. Taylor, Laura B. Ramsey, Torben Mikkelsen, Randal K. Buddington, Jesper Heldrup, Jason N. Barreto, Martin Guscott, Jennifer Lowe, Charles Hurmiz, Suresh Marada, Scott C. Howard & Paula Schaiquevich. (2022) Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing. British Journal of Clinical Pharmacology 89:2, pages 660-671.
Crossref
Crossref
Pattanaik Smita, Patil Amol Narayan, Kumaravel J & Prakash Gaurav. (2022) Therapeutic drug monitoring for cytotoxic anticancer drugs: Principles and evidence-based practices. Frontiers in Oncology 12.
Crossref
Crossref
Sharada Mailankody, Venkatesan Sampath Kumar, Shah Alam Khan, Shripad D. Banavali & Jyoti Bajpai. (2021) Resource‐appropriate selection of osteosarcoma treatment protocols in low‐ and middle‐income countries. Pediatric Blood & Cancer 69:3.
Crossref
Crossref
Tetsuichiro Isono, Daiki Hira, Aya Morikochi, Tadateru Fukami, Satoshi Ueshima, Kazuhiko Nozaki, Tomohiro Terada & Shin‐ya Morita. (2021) Urine volume to hydration volume ratio is associated with pharmacokinetics of high‐dose methotrexate in patients with primary central nervous system lymphoma. Pharmacology Research & Perspectives 9:6.
Crossref
Crossref
Jeena John, Manas Kinra, Jayesh Mudgal, G. L. Viswanatha & K. Nandakumar. (2021) Animal models of chemotherapy-induced cognitive decline in preclinical drug development. Psychopharmacology 238:11, pages 3025-3053.
Crossref
Crossref
Giuseppe Pesenti, Marco Foppoli & Davide Manca. (2021) A minimal physiologically based pharmacokinetic model for high-dose methotrexate. Cancer Chemotherapy and Pharmacology 88:4, pages 595-606.
Crossref
Crossref
Kim M. Stegmann, Antje Dickmanns, Sabrina Gerber, Vella Nikolova, Luisa Klemke, Valentina Manzini, Denise Schlösser, Cathrin Bierwirth, Julia Freund, Maren Sitte, Raimond Lugert, Gabriela Salinas, Toni Luise Meister, Stephanie Pfaender, Dirk Görlich, Bernd Wollnik, Uwe Groß & Matthias Dobbelstein. (2021) The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models. Virus Research 302, pages 198469.
Crossref
Crossref
Xuan Gao, Xiao-Wen Qian, Xiao-Hua Zhu, Yi Yu, Hui Miao, Jian-Hua Meng, Jun-Ye Jiang, Hong-Sheng Wang & Xiao-Wen Zhai. (2021) Population Pharmacokinetics of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia. Frontiers in Pharmacology 12.
Crossref
Crossref
Adam F. Binder, Samantha Burdette, Patricia Galanis, Katlin Birchmeier, Nathan Handley & Maria Piddoubny. (2020) Decreasing Cost and Decreasing Length of Stay After Implementation of Updated High-Dose Methotrexate Discharge Criteria. JCO Oncology Practice 16:8, pages e791-e796.
Crossref
Crossref
Jeerawan Klangjorhor, Areerak Phanphaisarn, Pimpisa Teeyakasem, Parunya Chaiyawat, Phichayut Phinyo, Jongkolnee Settakorn, Nipon Theera-Umpon & Dumnoensun Pruksakorn. (2020) In vitro drug sensitivity (IDS) of patient-derived primary osteosarcoma cells as an early predictor of the clinical outcomes of osteosarcoma patients. Cancer Chemotherapy and Pharmacology 85:6, pages 1165-1176.
Crossref
Crossref
Sophie Piperno‐Neumann, Isabelle Ray‐Coquard, Bob‐Valéry Occean, Valérie Laurence, Didier Cupissol, Christophe Perrin, Nicolas Penel, Emmanuelle Bompas, Maria Rios, Axel Le Cesne, Antoine Italiano, Philippe Anract, Gonzague Pinieux, Olivier Collard, François Bertucci, Florence Duffaud, Marie‐Cécile Le Deley, Jessy Delaye, Laurence Brugieres & Jean‐Yves Blay. (2019) Results of API–AI based regimen in osteosarcoma adult patients included in the French OS2006/Sarcome‐09 study. International Journal of Cancer 146:2, pages 413-423.
Crossref
Crossref
Thijs Oude Munnink, Alex van der Meer, Jacco de HaanDaan Touw & Michel van Kruchten. (2019) Reversible Impaired Methotrexate Clearance After Platinum-Based Chemotherapy for Osteosarcoma. Therapeutic Drug Monitoring 41:6, pages 693-695.
Crossref
Crossref
Sonoko Kawakatsu, Mina Nikanjam, Mark Lin, Sonny Le, Ila Saunders, Dennis John Kuo & Edmund V. Capparelli. (2019) Population pharmacokinetic analysis of high-dose methotrexate in pediatric and adult oncology patients. Cancer Chemotherapy and Pharmacology 84:6, pages 1339-1348.
Crossref
Crossref
Ka Ho Hui, Ho Man Chu, Pui Shan Fong, Wai Tsoi Frankie Cheng & Tai Ning Lam. (2019) Population Pharmacokinetic Study and Individual Dose Adjustments of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia or Osteosarcoma. The Journal of Clinical Pharmacology 59:4, pages 566-577.
Crossref
Crossref
Gabrielle Lui, Jean-Marc Treluyer, Brice Fresneau, Sophie Piperno-Neumann, Nathalie Gaspar, Nadège Corradini, Jean-Claude Gentet, Perrine Marec Berard, Valérie Laurence, Pascale Schneider, Natacha Entz-Werle, Hélène Pacquement, Frédéric Millot, Sophie Taque, Claire Freycon, Cyril Lervat, Marie Cécile Le Deley, Céline Mahier Ait Oukhatar, Laurence Brugieres, Gwénaël Le Teuff & Naïm Bouazza. (2018) A Pharmacokinetic and Pharmacogenetic Analysis of Osteosarcoma Patients Treated With High-Dose Methotrexate: Data From the OS2006/Sarcoma-09 Trial. The Journal of Clinical Pharmacology 58:12, pages 1541-1549.
Crossref
Crossref
Andrea Ferrari, Patrizia Gasparini, Jonathan GillRichard Gorlick. (2018) Challenges of Clinical Management of Adolescent and Young Adults With Bone and Soft Tissue Sarcoma. The Cancer Journal 24:6, pages 301-306.
Crossref
Crossref
Lu Ding, Chengwei Wang, Yong Cui, Xiaoping Han, Yang Zhou, Jingping Bai & Rong Li. (2018) S-phase kinase-associated protein 2 is involved in epithelial-mesenchymal transition in methotrexate-resistant osteosarcoma cells. International Journal of Oncology.
Crossref
Crossref
Yedidia Bentur & Yael Lurie. 2017. Critical Care Toxicology. Critical Care Toxicology
1171
1218
.
Yedidia Bentur & Yael Lurie. 2016. Critical Care Toxicology. Critical Care Toxicology
1
49
.
Wei Zhang, Qing Zhang, Xiaohuang Tian, Haitao Zhao, Wei Lu, Jiancun Zhen & Xiaohui Niu. (2015) Population Pharmacokinetics of High-dose Methotrexate After Intravenous Administration in Chinese Osteosarcoma Patients from a Single Institution. Chinese Medical Journal 128:1, pages 111-118.
Crossref
Crossref
Swen Seeland, Michael Török, Helene Kettiger, Alexander Treiber, Mathias Hafner & Jörg Huwyler. (2013) A cell-based, multiparametric sensor approach characterises drug-induced cytotoxicity in human liver HepG2 cells. Toxicology in Vitro 27:3, pages 1109-1120.
Crossref
Crossref
Marta Hegyi, Ágnes Gulácsi, Edit Cságoly, Katalin Csordás, Olivér T. Eipel, Dániel J. Erdélyi, Judit Müller, Karolina Nemes, Orsolya Lautner-Csorba & Gábor T. Kovács. (2012) Clinical relations of methotrexate pharmacokinetics in the treatment for pediatric osteosarcoma. Journal of Cancer Research and Clinical Oncology 138:10, pages 1697-1702.
Crossref
Crossref
Ali McBride, Scott J. Antonia, Eric B. Haura & Dawn Goetz. (2012) Suspected Methotrexate Toxicity From Omeprazole. Journal of Pharmacy Practice 25:4, pages 477-485.
Crossref
Crossref
Olivier Mir, Stanislas Ropert, Antoine Babinet, Jérôme Alexandre, Frédérique Larousserie, Jean-Philippe Durand, Eric Enkaoua, Philippe Anract & François Goldwasser. (2010) Hyper-alkalinization without hyper-hydration for the prevention of high-dose methotrexate acute nephrotoxicity in patients with osteosarcoma. Cancer Chemotherapy and Pharmacology 66:6, pages 1059-1063.
Crossref
Crossref
Helena Colom, Rosa Farré, Dolors Soy, Concepción Peraire, Josep-Maria Cendros, Nuria Pardo, Montserrat Torrent, Josep Domenech & Maria-Antonia Mangues. (2009) Population Pharmacokinetics of High-Dose Methotrexate After Intravenous Administration in Pediatric Patients With Osteosarcoma. Therapeutic Drug Monitoring 31:1, pages 76-85.
Crossref
Crossref
Jaishri O. Blakeley, Jeffrey Olson, Stuart A. Grossman, Xiaoying He, Jon Weingart & Jeffrey G. Supko. (2008) Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study. Journal of Neuro-Oncology 91:1, pages 51-58.
Crossref
Crossref
Silas W. Smith & Lewis S. Nelson. (2008) Case files of the New York City Poison Control Center: Antidotal strategies for the management of methotrexate toxicity. Journal of Medical Toxicology 4:2, pages 132-140.
Crossref
Crossref
Weiqun Xu, Yongmin Tang, Hua Song, Shuwen Shi & Shilong Yang. (2007) Retrospective Study on Elimination Delay of Methotrexate in High-dose Therapy of Childhood Acute Lymphoblastic Leukemia in China. Journal of Pediatric Hematology/Oncology 29:10, pages 688-693.
Crossref
Crossref
A. Saadat, N. Jonaidi Jafari, H. Khedmat, H.R. Jalalian, M. Izadi & M.J. Hosseini. (2007) Spontaneous Pneumothorax in a Patient with Osteosarcoma During Treatment with Methotrexate. International Journal of Pharmacology 3:2, pages 204-206.
Crossref
Crossref
Demiana William Faltaos, Jean Sebastian Hulot, Saïk Urien, Veronique Morel, Gentian Kaloshi, Christine Fernandez, khe Hoang Xuan, Veronique Leblond & Philippe Lechat. (2006) Population pharmacokinetic study of methotrexate in patients with lymphoid malignancy. Cancer Chemotherapy and Pharmacology 58:5, pages 626-633.
Crossref
Crossref