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Original Article

The effect of combretastatin A4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on water diffusion and blood perfusion in tumours

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Pages 1071-1076 | Received 04 Jul 2007, Published online: 08 Jul 2009

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Thomas Nielsen, Rumi Murata, Ross J. Maxwell, Hans Stødkilde-Jørgensen, Leif Østergaard, Carsten D. Ley, Paul E. G. Kristjansen & Michael R. Horsman. (2010) Non-invasive imaging of combretastatin activity in two tumor models: Association with invasive estimates. Acta Oncologica 49:7, pages 906-913.
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Shaker A. Abdul Hussein, Ammar Kubba, Asim A. Balakit, Lubna H. Tahtamouni & Ali H. Abbas. (2023) Design, Synthesis, in silico and in vitro Evaluation of New Combretastatin A-4 Analogs as Antimitotic Antitumor Agents. Medicinal Chemistry 19:10, pages 1018-1036.
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María-Jesús Pérez-Pérez, Eva-María Priego, Oskía Bueno, Maria Solange Martins, María-Dolores Canela & Sandra Liekens. (2016) Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth. Journal of Medicinal Chemistry 59:19, pages 8685-8711.
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Huaijun Wang, Marlein Miranda Cona, Feng Chen, Jie Yu, Yuanbo Feng, Junjie Li, Frederik De Keyzer, Guy Marchal & Yicheng Ni. (2012) Comparison of two vascular-disrupting agents at a clinically relevant dose in rodent liver tumors with multiparametric magnetic resonance imaging biomarkers. Anti-Cancer Drugs 23:1, pages 12-21.
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Sarah E. Bohndiek, Mikko I. Kettunen, De-en Hu, Timothy H. Witney, Brett W.C. Kennedy, Ferdia A. Gallagher & Kevin M. Brindle. (2010) Detection of Tumor Response to a Vascular Disrupting Agent by Hyperpolarized 13C Magnetic Resonance Spectroscopy. Molecular Cancer Therapeutics 9:12, pages 3278-3288.
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Huaijun Wang, Junjie Li, Feng Chen, Frederik De Keyzer, Jie Yu, Yuanbo Feng, Johan Nuyts, Guy Marchal & Yicheng Ni. (2010) Morphological, functional and metabolic imaging biomarkers: assessment of vascular-disrupting effect on rodent liver tumours. European Radiology 20:8, pages 2013-2026.
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George R. Pettit, Mathew D. Minardi, Fiona Hogan & Pat M. Price. (2009) An Efficient Synthetic Strategy for Obtaining 4-Methoxy Carbon Isotope Labeled Combretastatin A-4 Phosphate and Other Z -Combretastatins . Journal of Natural Products 73:3, pages 399-403.
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Lesley D. McPhail & Simon P. Robinson. 2010. Vascular Disruptive Agents for the Treatment of Cancer. Vascular Disruptive Agents for the Treatment of Cancer 95 116 .
Robin K. Pettit, George R. Pettit, Ernest Hamel, Fiona Hogan, Bryan R. Moser, Sonja Wolf, Sandy Pon, Jean-Charles Chapuis & Jean M. Schmidt. (2009) E-Combretastatin and E-resveratrol structural modifications: Antimicrobial and cancer cell growth inhibitory β-E-nitrostyrenes. Bioorganic & Medicinal Chemistry 17:18, pages 6606-6612.
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Xihe Sun, Huaijun Wang, Feng Chen, Frederik De Keyzer, Jie Yu, Yansheng Jiang, Yuanbo Feng, Junjie Li, Guy Marchal & Yicheng Ni. (2009) Diffusion-weighted MRI of hepatic tumor in rats: Comparison between in vivo and postmortem imaging acquisitions. Journal of Magnetic Resonance Imaging 29:3, pages 621-628.
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