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Original Article

Carcinoma ex pleomorphic adenoma of the parotid gland. Study and implications for diagnostics and therapy

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Pages 132-136 | Received 10 Jan 2008, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Shujie Song, Ping Sui, Minmin Li, Liangming Zhang & Dengjun Sun. (2019) Anlotinib is effective in the treatment of advanced carcinoma ex pleomorphic adenoma of the submandibular gland. OncoTargets and Therapy 12, pages 4093-4097.
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Masahiro Suzuki, Takashi Matsuzuka, Satoshi Saijo, Miki Takahara, Yasuaki Harabuchi, Tsuyoshi Okuni, Tetsuo Himi, Tomohiko Kakizaki, Satoshi Fukuda, Kazuyuki Yamada, Tatsumi Nagahashi, Takahisa Abe, Hideichi Shinkawa, Katsunori Katagiri, Hiroaki Sato, Naoko Fukui, Kazuo Ishikawa, Takahiro Suzuki, Toshimitsu Kobayashi, Daisuke Saito, Shigeru Saijo, Masaru Tateda, Sho Hashimoto, Akihiro Ishida, Seiji Kakehata, Osamu Suzuki, Yuko Hashimoto & Koichi Omori. (2016) Carcinoma ex pleomorphic adenoma of the parotid gland: a multi-institutional retrospective analysis in the Northern Japan Head and Neck Cancer Society. Acta Oto-Laryngologica 136:11, pages 1154-1158.
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Articles from other publishers (42)

Ishank Panchal & Anil Wanjari. (2023) Pleomorphic Adenoma of a Minor Salivary Gland of the Hard Palate: A Case Report. Cureus.
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Shengwen Liu, Hao Lu, Limin Liu, Yifan Wu, Yun Zhu, Wanlin Xu, Wenjun Yang & Chenping Zhang. (2022) Carcinoma ex pleomorphic adenoma of the submandibular gland: A retrospective analysis of 86 patients. Oral Diseases 29:4, pages 1602-1612.
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Hyojin Kim, Shin Eun, Woo-Jin Jeong, Soon-Hyun Ahn, Yun Jung Bae, Joong Seob Lee & Heejin Kim. (2022) Identification of differentially expressed microRNAs as potential biomarkers for carcinoma ex pleomorphic adenoma. Scientific Reports 12:1.
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Keerthan Dhanasekar, Heena Kapadia, Steven Neilaj, Meriam Abdeslem & Ganapathy Dhanasekar. (2021) Melon-sized Parotid Pleomorphic Adenoma—A Case Report. Indian Journal of Otolaryngology and Head & Neck Surgery 74:S3, pages 5391-5394.
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Seraphina Key, Clemente Chia, Zubair Hasan, Purnima Sundaresan, Raghav C Dwivedi & Faruque Riffat. (2022) Systematic review of prognostic factors in carcinoma ex pleomorphic adenoma. Oral Oncology 133, pages 106052.
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Atsuko Niki-Yonekawa, Yoshihiro Morita, Yukiko Kusuyama, Yoshio Ueno, Satoko Kishimoto, Nobuo Morita & Narikazu Uzawa. (2022) Carcinoma ex pleomorphic adenoma in an elderly patient: A case report and literature review. Oral and Maxillofacial Surgery Cases 8:3, pages 100272.
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Michał Żurek, Kamil Jasak, Karolina Jaros, Piotr Daniel, Kazimierz Niemczyk & Anna Rzepakowska. (2022) Clinico-Epidemiological Analysis of Most Prevalent Parotid Gland Carcinomas in Poland over a 20-Year Period. International Journal of Environmental Research and Public Health 19:16, pages 10247.
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Sung Yong Choi, Jaehyuck Choi, Inwoo Hwang, Junhun Cho, Young-Hyeh Ko & Han-Sin Jeong. (2022) Comparative Longitudinal Analysis of Malignant Transformation in Pleomorphic Adenoma and Recurrent Pleomorphic Adenoma. Journal of Clinical Medicine 11:7, pages 1808.
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Luccas Lavareze, João Figueira Scarini, Reydson Alcides de Lima-Souza, Carolina Emerick, Raísa Sales de Sá, Iara Gonçalves Aquino, Patricia Maria Fernandes, Mayara Trevizol Gonçalves, My N. Helms, Albina Altemani, Erika Said Abu Egal & Fernanda Viviane Mariano. (2022) Salivary gland cancer in the setting of tumor microenvironment: Translational routes for therapy. Critical Reviews in Oncology/Hematology 171, pages 103605.
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Pari Jafari, Kathleen E. Higgins & Nicole A. Cipriani. (2021) Challenges in the Diagnosis of Myoepithelial-Rich Salivary Gland Neoplasms. AJSP: Reviews and Reports 26:5, pages 270-282.
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Joana Borges da Costa, Ana Isabel Goncalves, Andre Carcao, Joana Santos, Delfim Duarte & Miguel Viana. (2021) Carcinoma Ex Pleomorphic Adenoma of the Uvula - Case Report. Journal of Biomedical Research & Environmental Sciences 2:7, pages 543-547.
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Steven A. Rooker, Kathryn M. Van Abel, Linda X. Yin, Alex A. Nagelschneider, Daniel L. Price, Kerry D. Olsen, Jeffrey R. Janus, Jan L. Kasperbauer & Eric J. Moore. (2020) Risk factors for subsequent recurrence after surgical treatment of recurrent pleomorphic adenoma of the parotid gland. Head & Neck 43:4, pages 1088-1096.
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Maximilian Linxweiler, Jingming Wang & Luc G.T Morris. (2021) The role of immune surveillance in malignant transformation of benign salivary gland tumors. Oncotarget 12:7, pages 592-595.
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Mirco Schapher, Michael Koch, Miguel Goncalves, Konstantinos Mantsopoulos & Heinrich Iro. (2020) Extracapsular Dissection in Pleomorphic Adenomas of the Parotid Gland: Results After 13 Years of Follow‐up. The Laryngoscope 131:2.
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Evan J. Patel, Jamie R. Oliver, Cheng Liu, Moses Tam & Babak Givi. (2020) Outcomes of carcinoma ex pleomorphic adenoma compared to de novo adenocarcinoma of major salivary glands. Journal of Surgical Oncology 123:2, pages 446-455.
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Indraneel Bhattacharyya & Hardeep K. Chehal. 2021. Sjögren's Syndrome and Oral Health. Sjögren's Syndrome and Oral Health 139 165 .
Yuhua Hu, Liang Xia, Chunye Zhang, Ronghui Xia, Zhen Tian & Jiang Li. (2020) Clinicopathologic Features and Prognostic Factors of Widely Invasive Carcinoma Ex Pleomorphic Adenoma of Parotid Gland: A Clinicopathologic Analysis of 126 Cases in a Chinese Population. Journal of Oral and Maxillofacial Surgery 78:12, pages 2247-2257.
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Grace Paka Lubamba, Guan Jian, Wang Xin Yu, Zhang Guo liang, Ning Shang Bo, Dai Xin Peng & Fidele Nyimi Bushabu. (2020) Submandibular gland carcinoma ex pleomorphic adenoma clinically mimicking a benign lesion. Oral and Maxillofacial Surgery Cases 6:3, pages 100166.
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Geeta Ahuja, Delaram J. Taghipour, Olubode A. Olufajo, Bonnie C. Davis, Babak Shokrani & William R. Bond. (2020) A Rare De Novo Myoepithelial Carcinoma Ex Pleomorphic Adenoma in a Young Woman. Case Reports in Otolaryngology 2020, pages 1-6.
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Avigeet Gupta, Sina Koochakzadeh, David M. Neskey, Shaun A. Nguyen & Eric J. Lentsch. (2019) Carcinoma ex pleomorphic adenoma: A review of incidence, demographics, risk factors, and survival. American Journal of Otolaryngology 40:6, pages 102279.
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S.K. Rajappa, Y.S. Bhakuni, D. Ram, H. Shukla, R. Ranjan, A. Dewan, S. Dabas & A.K. Dewan. (2018) A gland of diverse pathology and unpredictable behaviour: our experience of primary submandibular gland malignancies. International Journal of Oral and Maxillofacial Surgery 47:10, pages 1243-1249.
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Anbukkani Subbian, Preithy Uthamalingam, Moumita Bag, Sangita S. Mehta, Firoz Rajan & R. Renuka Devi. (2018) Malignant Transformation of Pleomorphic Adenoma of Vulva: Report of a Rare Case and Review of Literature. Indian Journal of Gynecologic Oncology 16:3.
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Bruno Tavares Sedassari, Maria Fernanda Setúbal Destro Rodrigues, Thalita Santana Conceição, Fernanda Viviane Mariano, Venâncio Avancini Ferreira Alves, Fábio Daumas Nunes, Albina Altemani & Suzana Cantanhede Orsini Machado de Sousa. (2017) Increased SOX2 expression in salivary gland carcinoma ex pleomorphic adenoma progression: an association with adverse outcome. Virchows Archiv 471:6, pages 775-784.
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Gi Hyun Gim, Young Jin Roh, Min Gyoung Pak & Jong Chul Hong. (2017) Minimally Invasive Carcinoma ex Pleomorphic Adenoma Arising from Parotid Gland. Journal of Clinical Otolaryngology Head and Neck Surgery 28:1, pages 100-103.
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Stephan Ihrler, Orlando Guntinas-Lichius, Abbas Agaimy, Agnes Wolf & Martin Mollenhauer. (2017) Histological, immunohistological and molecular characteristics of intraductal precursor of carcinoma ex pleomorphic adenoma support a multistep carcinogenic process. Virchows Archiv 470:6, pages 601-609.
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Madalina Tuluc, Voichita Bar-Ad, David Cognetti, Jennifer Johnson & Rita Axelrod. 2017. Textbook of Uncommon Cancer. Textbook of Uncommon Cancer 134 151 .
Lauren M. Thorpe, Alexa B. Schrock, Rachel L. Erlich, Vincent A. Miller, James Knost, Nguyet Le‐Lindqwister, Srinivas Jujjavarapu, Siraj M. Ali & Jane J. Liu. (2016) Significant and durable clinical benefit from trastuzumab in 2 patients with HER2 ‐amplified salivary gland cancer and a review of the literature . Head & Neck 39:3.
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Soussan Irani & Farahnaz Bidari-Zerehpoush. (2017) BRCA1/2 mutations in salivary pleomorphic adenoma and carcinoma-ex-pleomorphic adenoma. Journal of International Society of Preventive and Community Dentistry 7:9, pages 155.
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. 2017. Diagnostic Imaging: Head and Neck. Diagnostic Imaging: Head and Neck 106 107 .
Yu-Hua Hu, Chun-Ye Zhang, Rong-Hui Xia, Zhen Tian, Li-Zhen Wang & Jiang Li. (2016) Prognostic factors of carcinoma ex pleomorphic adenoma of the salivary glands, with emphasis on the widely invasive carcinoma: a clinicopathologic analysis of 361 cases in a Chinese population. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 122:5, pages 598-608.
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Kevin Y. Zhan, Sobia F. Khaja, Allen B. Flack & Terry A. Day. (2016) Benign Parotid Tumors. Otolaryngologic Clinics of North America 49:2, pages 327-342.
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Fredrik Petersson. (2015) High-Grade Transformation (“Dedifferentiation”)—Malignant Progression of Salivary Gland Neoplasms, Including Carcinoma ex Pleomorphic Adenoma. Pathology Case Reviews 20:1, pages 27-37.
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Jianqiang Zhao, Jiafeng Wang, Chang Yu, Liang Guo, Kejing Wang, Zhong Liang & Jianlin Lou. (2013) Prognostic factors affecting the clinical outcome of carcinoma ex pleomorphic adenoma in the major salivary gland. World Journal of Surgical Oncology 11:1.
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Naohiro Yoshida, Mariko Hara, Hiromi Kanazawa & Yukiko Iino. (2013) Large Carcinoma ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Review of Literature. Journal of Oral and Maxillofacial Surgery 71:12, pages 2196.e1-2196.e6.
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Akshay Kudpaje, Sumit Gupta, Sudhir Naik, Rajshekar Halkud, Siddharth Biswas, Ashok M Shenoy, Purshottam Chavan & Mahesh Kalloli. (2013) Carcinoma Expleomorphic Adenoma of the Submandibular Gland. Journal of Postgraduate Medicine, Education and Research 47:3, pages 162-166.
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Heinrich Iro, Johannes Zenk, Michael Koch & Nils Klintworth. (2012) Follow‐up of parotid pleomorphic adenomas treated by extracapsular dissection. Head & Neck 35:6, pages 788-793.
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Mohammed Nadershah, Ahmed Alshadwi & Andrew Salama. (2013) An Unusual Case of Carcinoma Ex Pleomorphic Adenoma of the Parotid Metastasizing to the Mandible: Case Report and Review of the Literature. Journal of Oral and Maxillofacial Surgery 71:2, pages 437-442.
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Kazuo Sano, Shuichi Fujita, Joji Sekine, Masataka Uehara, Noriyuki Sakihama, Tomayoshi Hayashi, Hitoshi Yoshimura & Takayoshi Tobita. (2012) Metachronous Manifestation of Carcinoma Ex Pleomorphic Adenoma in a Buccal Minor Salivary Gland and the Contralateral Parotid Gland: A Case Report and Review of the Literature. Journal of Oral and Maxillofacial Surgery 70:11, pages 2701-2712.
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Joyce Antony, Vinod Gopalan, Robert A. Smith & Alfred K. Y. Lam. (2011) Carcinoma ex Pleomorphic Adenoma: A Comprehensive Review of Clinical, Pathological and Molecular Data. Head and Neck Pathology 6:1, pages 1-9.
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Voichita Bar‐Ad, Madalina Tuluc, David Cognetti & Rita Axelrod. 2012. Textbook of Uncommon Cancer. Textbook of Uncommon Cancer 97 117 .
D'Cruz Anil, Dandekar Mitali, Chaukar Devendra, Kane Shubhada & Juvekar Shashikant. (2010) Intracapsular Carcinoma ex Pleomorphic Adenoma in the Buccal Space: Management Dilemma. International Journal of Head and Neck Surgery 1:1, pages 21-24.
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