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Scandinavian Journal of Rheumatology Volume 30, 2001 - Issue 3
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Research Article

Antinuclear antibody screening in this new millennium: farewell to the microscope?

Hans Nossent, Ole Petter Rekvig Department of Rheumatology, Department of Immunology and Transfusion Medicine, University Hospital Tromsu , Norway
Pages 123-126 | Published online: 12 Jul 2009

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Jan MM Rondeel. (2002) Immunofluorescence versus ELISA for the detection of antinuclear antigens. Expert Review of Molecular Diagnostics 2:3, pages 226-232.
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Luigi Cinquanta, Maria Infantino, Mariangela Manfredi, Massimo Daves, Antonella Radice, Danilo Villalta, Maria Concetta Sorrentino, Brunetta Porcelli, Lucia Terzuoli, Marcello Bagnasco, Ignazio Brusca & Nicola Bizzaro. (2020) Aggiornamento delle linee guida SIPMeL sull'utilizzo dei test autoanticorpali nella diagnosi e nel monitoraggio delle malattie autoimmuni reumatiche sistemiche: metodi per lo screening degli anticorpi anti-antigeni cellulari (ANA). La Rivista Italiana della Medicina di Laboratorio 15:4.
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Nancy J. Olsen, May Y. Choi & Marvin J. Fritzler. (2017) Emerging technologies in autoantibody testing for rheumatic diseases. Arthritis Research & Therapy 19:1.
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Luigi Cinquanta, Desré Ethel Fontana & Nicola Bizzaro. (2017) Chemiluminescent immunoassay technology: what does it change in autoantibody detection?. Autoimmunity Highlights 8:1.
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Thomas Bahmer, Micaela Romagnoli, Francesco Girelli, Martin Claussen & Klaus F. Rabe. (2016) The use of auto-antibody testing in the evaluation of interstitial lung disease (ILD) – A practical approach for the pulmonologist. Respiratory Medicine 113, pages 80-92.
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Luigi Cinquanta, Nicola Bizzaro, Danilo Villalta, Gabriella Morozzi, Elio Tonutti, Marcello Bagnasco, Giampaola Pesce, Danila Bassetti, Brunetta Porcelli, Lucia Terzuoli, Antonio Antico, Antonella Radice, Gaia Deleonardi, Marilina Tampoia & Renato Tozzoli. (2015) Linee guida per l’utilizzo dei test autoanticorpali nella diagnosi e nel monitoraggio delle malattie autoimmuni reumatiche sistemiche. Revisione 2015Guidelines for the laboratory use of autoantibody tests in the diagnosis and monitoring of autoimmune rheumatic diseases. Revision 2015. La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine 11:4, pages 205-224.
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R Hira-Kazal, P Shea-Simonds, J L Peacock & J Maher. (2015) How should a district general hospital immunology service screen for anti-nuclear antibodies? An ‘in-the-field’ audit. Clinical and Experimental Immunology 180:1, pages 52-57.
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Renata Baronaite, Merete Engelhart, Troels Mørk Hansen, Gorm Thamsborg, Hanne Slott Jensen, Steen Stender & Pal Bela Szecsi. (2014) A Comparison of Anti-Nuclear Antibody Quantification Using Automated Enzyme Immunoassays and Immunofluorescence Assays. Autoimmune Diseases 2014, pages 1-8.
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Michael Mahler, Pier-Luigi Meroni, Xavier Bossuyt & Marvin J. Fritzler. (2014) Current Concepts and Future Directions for the Assessment of Autoantibodies to Cellular Antigens Referred to as Anti-Nuclear Antibodies. Journal of Immunology Research 2014, pages 1-18.
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Fabiano de Almeida Brito, Silvana Maria Elói Santos, Gilda Aparecida Ferreira, William Pedrosa, Janaina Gradisse, Lara Cristina Costa & Suzane Pretti Figueiredo Neves. (2014) Detection of anti-nuclear antibodies by indirect immunofluorescence on HEp-2 cells: setting the appropriate screening dilution for the diagnosis of autoimmune rheumatic diseases. Revista Brasileira de Reumatologia (English Edition) 54:1, pages 13-20.
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Fabiano de Almeida Brito, Silvana Maria Elói Santos, Gilda Aparecida Ferreira, William Pedrosa, Janaina Gradisse, Lara Cristina Costa & Suzane Pretti Figueiredo Neves. (2014) Detecção de anticorpos antinucleares por imunofluorescência indireta em células HEp-2: definindo a diluição de triagem adequada para o diagnóstico das doenças reumáticas autoimunes. Revista Brasileira de Reumatologia 54:1, pages 13-20.
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Mira Barak, Orit Rozenberg, Maya Grinberg, Dina Reginashvili, Maya Kishinewsky, Clara Henig & Paul Froom. (2013) A novel cost effective algorithm for antinuclear antibody (ANA) testing in an outpatient setting. Clinical Chemistry and Laboratory Medicine 51:7.
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SS Hasson, MS Al-Balushi & AA Al-Jabri. (2012) The role of the autoimmunity laboratory in autoimmune diseases. Asian Pacific Journal of Tropical Disease 2:2, pages 159-162.
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Ellen Nordal, Nils T. Songstad & Marite Rygg. (2011) Difficulties in defining antinuclear antibody–positive patients as a separate category in the classification of juvenile idiopathic arthritis: Comment on the article by Ravelli et al. Arthritis & Rheumatism 63:9, pages 2835-2835.
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Dhanita Khanna & Arun Shrivastava. (2011) ACR classification criteria for SLE: A logical analysis. Are “diagnostic” criteria required?. Indian Journal of Rheumatology 6:2, pages 84-87.
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Peter H. Schur. 2011. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 629 653 .
T. Skogh & C. Dahle. (2009) Comment on: Clinical utility of ANA measured by ELISA compared with ANA measured by immunofluorescence. Rheumatology 49:2, pages 396-397.
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ELLEN B. NORDAL, NILS T. SONGSTAD, LILLEMOR BERNTSON, TOROLF MOEN, BJØRN STRAUME & MARITE RYGG. (2009) Biomarkers of Chronic Uveitis in Juvenile Idiopathic Arthritis: Predictive Value of Antihistone Antibodies and Antinuclear Antibodies. The Journal of Rheumatology 36:8, pages 1737-1743.
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GRO ØSTLI EILERTSEN, ANDREA BECKER-MEROK & JOHANNES C. NOSSENT. (2009) The Influence of the 1997 Updated Classification Criteria for Systemic Lupus Erythematosus: Epidemiology, Disease Presentation, and Patient Management. The Journal of Rheumatology 36:3, pages 552-559.
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Marjan Van Blerk, Christel Van Campenhout, Xavier Bossuyt, Jean Duchateau, René Humbel, Geneviève Servais, Jean-Paul Tomasi, Adelin Albert, Wim Coucke & Jean-Claude Libeer. (2009) Current practices in antinuclear antibody testing: results from the Belgian External Quality Assessment Scheme. Clinical Chemistry and Laboratory Medicine 47:1.
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P. GHILLANI, A. M. ROUQUETTE, C. DESGRUELLES, N. HAUGUEL, C. LE PENDEVEN, J. C. PIETTE & L. MUSSET. (2007) Evaluation of the LIAISON ANA Screen Assay for Antinuclear Antibody Testing in Autoimmune Diseases. Annals of the New York Academy of Sciences 1109:1, pages 407-413.
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MARCOS LÓPEZ‐HOYOS, VICENTE RODRÍGUEZ‐VALVERDE & VICTOR MARTINEZ‐TABOADA. (2007) Performance of Antinuclear Antibody Connective Tissue Disease Screen. Annals of the New York Academy of Sciences 1109:1, pages 322-329.
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Ehud Paz, Muhammed Adawi, Idit Lavi, Yehuda Mussel & Reuven Mader. (2007) Antinuclear antibodies measured by enzyme immunoassay in patients with systemic lupus erythematosus: relation to disease activity. Rheumatology International 27:10, pages 941-945.
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SR Binder. (2016) Autoantibody Detection Using Multiplex Technologies. Lupus 15:7, pages 412-421.
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Alain Chevailler, Céline Beauvillain & François Carrère. (2006) Dépistage des anticorps dirigéscontre les an tigènes nucléaires solubles. Revue Francophone des Laboratoires 2006:384, pages 59-70.
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José M. González-Buitrago & Concepción González. (2006) Present and future of the autoimmunity laboratory. Clinica Chimica Acta 365:1-2, pages 50-57.
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Concepción González, Belén García-Berrocal, Marta Pérez, José A. Navajo, Oscar Herraez & José M. González-Buitrago. (2005) Laboratory screening of connective tissue diseases by a new automated ENA screening assay (EliA Symphony) in clinically defined patients. Clinica Chimica Acta 359:1-2, pages 109-114.
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Mogens Fenger, Allan Wiik, Mimi Høier-Madsen, Jens J Lykkegaard, Teresa Rozenfeld, Michael S Hansen, Bente Danneskjold Samsoe & Søren Jacobsen. (2004) Detection of Antinuclear Antibodies by Solid-Phase Immunoassays and Immunofluorescence Analysis. Clinical Chemistry 50:11, pages 2141-2147.
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Charlotte Dahle, Thomas Skogh, A.K. Åberg, A. Jalal & P. Olcén. (2004) Methods of choice for diagnostic antinuclear antibody (ANA) screening. Journal of Autoimmunity 22:3, pages 241-248.
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Sergio Bernardini, Maria Infantino, Lorenza Bellincampi, Marzia Nuccetelli, Antonella Afeltra, Roberta Iori, Antonino Biroccio, Andrea Urbani & Giorgio Federici. (2004) Screening of antinuclear antibodies: comparison between enzyme immunoassay based on nuclear homogenates, purified or recombinant antigens and immunofluorescence assay. Clinical Chemistry and Laboratory Medicine (CCLM) 42:10.
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