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Research Article

Decreased production of interleukin-12 and interferon-? is associated with renal involvement in systemic lupus erythematosus

Pages 159-163 | Published online: 12 Jul 2009

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P. Enghard, D. Langnickel & G. Riemekasten. (2006) T cell cytokine imbalance towards production of IFN‐γ and IL‐10 in NZB/W F1 lupus‐prone mice is associated with autoantibody levels and nephritis. Scandinavian Journal of Rheumatology 35:3, pages 209-216.
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Chang-Youh Tsai, Tsai-Hung Wu, Chia-Li Yu, Ying-Yang Tsai & Chung-Tei Chou. (2002) DECREASED IL-12 PRODUCTION BY POLYMORPHONUCLEAR LEUKOCYTES IN PATIENTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS. Immunological Investigations 31:3-4, pages 177-189.
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Articles from other publishers (33)

Surjyapratap Sarangi, Suraj K Nahak, Sunali Padhi, Bidyutprabha Pradhan, Nisha Nayak, Abhijit Pati & Aditya K Panda. (2022) Interferon-gamma (IFN-γ) intronic variant (rs2430561) is a risk factor for systemic lupus erythematosus: Observation from a meta-analysis. Lupus 32:2, pages 284-294.
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Alexandra Linke, Gisa Tiegs & Katrin Neumann. (2022) Pathogenic T-Cell Responses in Immune-Mediated Glomerulonephritis. Cells 11:10, pages 1625.
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Karen Lizeth Rincón-Delgado, Catherin Tovar-Sánchez, Daniel G. Fernández-Ávila & Luz-Stella Rodríguez C.. (2021) Role of cytokines in the pathophysiology of systemic lupus erythematosus. Revista Colombiana de Reumatología 28, pages 144-155.
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Zeineb Zian, Assia Bouhoudan, Nadira Mourabit, Gholamreza Azizi & Mohcine Bennani Mechita. (2021) Salivary Cytokines as Potential Diagnostic Biomarkers for Systemic Lupus Erythematosus Disease. Mediators of Inflammation 2021, pages 1-10.
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Hiroshi Kato & Andras Perl. (2021) Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8+ T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus. Frontiers in Immunology 12.
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Bonnia Liu & Alberta Hoi. 2021. Pathogenesis of Systemic Lupus Erythematosus. Pathogenesis of Systemic Lupus Erythematosus 109 131 .
Visnja Kokic, Dusanka Martinovic Kaliterna, Mislav Radic, Leida Tandara & Dijana Perkovic. (2017) Association between vitamin D, oestradiol and interferon-gamma in female patients with inactive systemic lupus erythematosus: A cross-sectional study. Journal of International Medical Research 46:3, pages 1162-1171.
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Mohsen Honarpisheh, Paulina Köhler, Ekaterina von Rauchhaupt & Maciej Lech. (2018) The Involvement of MicroRNAs in Modulation of Innate and Adaptive Immunity in Systemic Lupus Erythematosus and Lupus Nephritis. Journal of Immunology Research 2018, pages 1-15.
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Wahid Ali Khan. 2017. Lupus. Lupus.
Feng Qiu, Tingting Li, Kui Zhang, Jun Wan & Xiaokun Qi. (2016) CD4+B220+TCRγδ+ T cells produce IL-17 in lupus-prone MRL/lpr mice. International Immunopharmacology 38, pages 31-39.
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Hiroshi Kato & Andras Perl. (2014) Mechanistic Target of Rapamycin Complex 1 Expands Th17 and IL-4+ CD4−CD8− Double-Negative T Cells and Contracts Regulatory T Cells in Systemic Lupus Erythematosus. The Journal of Immunology 192:9, pages 4134-4144.
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M Kawasaki, M Fujishiro, A Yamaguchi, K Nozawa, H Kaneko, Y Takasaki, K Takamori, H Ogawa & I Sekigawa. (2011) Possible role of the JAK/STAT pathways in the regulation of T cell-interferon related genes in systemic lupus erythematosus. Lupus 20:12, pages 1231-1239.
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Kim Ohl & Klaus Tenbrock. (2011) Inflammatory Cytokines in Systemic Lupus Erythematosus. Journal of Biomedicine and Biotechnology 2011, pages 1-14.
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Antonio La Cava. (2010) Anticytokine therapies in systemic lupus erythematosus. Immunotherapy 2:4, pages 575-582.
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Lars Rönnblom & Keith B. Elkon. (2010) Cytokines as therapeutic targets in SLE. Nature Reviews Rheumatology 6:6, pages 339-347.
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Zhe Zhang, Kelly Maurer, Juan C. Perin, Li Song & Kathleen E. Sullivan. (2010) Cytokine-Induced Monocyte Characteristics in SLE. Journal of Biomedicine and Biotechnology 2010, pages 1-13.
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Dong Wang, Melanie Drenker, Britta Eiz‐Vesper, Thomas Werfel & Miriam Wittmann. (2008) Evidence for a pathogenetic role of interleukin‐18 in cutaneous lupus erythematosus. Arthritis & Rheumatism 58:10, pages 3205-3215.
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F. Goldblatt & D. A. Isenberg. 2008. Therapeutic Antibodies. Therapeutic Antibodies 163 181 .
Marut Tangwattanachuleeporn, Pimpayao Sodsai, Yingyos Avihingsanon, Jongkonnee Wongpiyabovorn, Jeerapat Wongchinsri & Nattiya Hirankarn. (2007) Association of interferon-gamma gene polymorphism (+874A) with arthritis manifestation in SLE. Clinical Rheumatology 26:11, pages 1921-1924.
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J DongQ-X Wang, C-Y Zhou, X-F Ma & Y-C Zhang. (2016) Activation of the STAT1 signalling pathway in lupus nephritis in MRL/lpr mice. Lupus 16:2, pages 101-109.
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Rebecca Wing-Yan Chan, Fernand Mac-Moune Lai, Edmund Kwok-Ming Li, Lai-Shan Tam, Kai-Ming Chow, Philip Kam-Tao Li & Cheuk-Chun Szeto. (2006) The effect of immunosuppressive therapy on the messenger RNA expression of target genes in the urinary sediment of patients with active lupus nephritis. Nephrology Dialysis Transplantation 21:6, pages 1534-1540.
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Weimin DengQin HanLianming LiaoShengguo YouHongye DengRobert C.H. Zhao. (2005) Effects of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells on T and B Lymphocytes from BXSB Mice. DNA and Cell Biology 24:7, pages 458-463.
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Jean Sibilia & Christelle Sordet. (2005) Immunothérapies du lupus systémique : innovations et perspectives. Revue du Rhumatisme 72:6, pages 572-591.
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F Goldblatt & D A Isenberg. (2005) New therapies for systemic lupus erythematosus. Clinical and Experimental Immunology 140:2, pages 205-212.
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Gabor G. Illei, Edward Tackey, Larissa Lapteva & Peter E. Lipsky. (2004) Biomarkers in systemic lupus erythematosus: II. Markers of disease activity. Arthritis & Rheumatism 50:7, pages 2048-2065.
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Diana Gómez, Paula A. Correa, Luis Miguel Gómez, José Cadena, José F. Molina & Juan-Manuel Anaya. (2004) Th1/Th2 cytokines in patients with systemic lupus erythematosus: is tumor necrosis factor α protective?. Seminars in Arthritis and Rheumatism 33:6, pages 404-413.
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C Gorman, M Leandro & D Isenberg. (2016) Does B cell depletion have a role to play in the treatment of systemic lupus erythematosus?. Lupus 13:5, pages 312-316.
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Nicola Calvani, Minoru Satoh, Byron P. Croker, Westley H. Reeves & Hanno B. Richards. (2003) Nephritogenic autoantibodies but absence of nephritis in Il-12p35–deficient mice with pristane-induced lupus. Kidney International 64:3, pages 897-905.
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Bisram Deocharan, Paola Marambio, Morris Edelman & Chaim Putterman. (2003) Differential effects of interleukin-4 in peptide induced autoimmunity. Clinical Immunology 108:2, pages 80-88.
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Susanne J. SzaboBrandon M. SullivanStanford L. PengLaurie H. Glimcher. (2003) Molecular Mechanisms RegulatinG Th1 Immune Responses. Annual Review of Immunology 21:1, pages 713-758.
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Jim C. Oates & Gary S. Gilkeson. (2002) Mediators of injury in lupus nephritis. Current Opinion in Rheumatology 14:5, pages 498-503.
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Amy M Beebe, Daniel J Cua & Rene de Waal Malefyt. (2002) The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS). Cytokine & Growth Factor Reviews 13:4-5, pages 403-412.
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Hideyuki Murata, Ryutaro Matsumura, Akio Koyama, Takao Sugiyama, Makoto Sueishi, Kazuko Shibuya, Akito Tsutsumi & Takayuki Sumida. (2002) T cell receptor repertoire of T cells in the kidneys of patients with lupus nephritis. Arthritis & Rheumatism 46:8, pages 2141-2147.
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