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Research Article

Efficacy and safety of iguratimod on patients with primary Sjögren’s syndrome: a randomized, placebo-controlled clinical trial

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Pages 143-152 | Accepted 10 Aug 2020, Published online: 29 Oct 2020

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Soledad Retamozo, Antoni Sisó-Almirall, Alejandra Flores-Chávez, Manuel Ramos-Casals & Pilar Brito-Zerón. (2021) An update of targeted therapeutic options for primary Sjögren syndrome: current status and future development. Expert Opinion on Pharmacotherapy 22:17, pages 2359-2371.
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Articles from other publishers (15)

Lu Shi, Jinyu Hu, Hualu Wu, Yuxin Shen, Xiaohai Chen, Qinghua Weng, Ren-ai Xu & Congrong Tang. (2024) Simultaneous determination of iguratimod and its metabolite in rat plasma using a UPLC-MS/MS method: Application for drug-drug interaction. Journal of Pharmaceutical and Biomedical Analysis 243, pages 116079.
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Yann Nguyen, Maxime Beydon, Nathan Foulquier, Rachael Gordon, Coralie Bouillot, Katherine M Hammitt, Simon J Bowman, Xavier Mariette, Sara S McCoy, Divi Cornec & Raphaèle Seror. (2024) Identification of outcome domains in primary Sjögren's disease: A scoping review by the OMERACT Sjögren disease working group. Seminars in Arthritis and Rheumatism 65, pages 152385.
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Nadine Zehrfeld, Torsten Witte & Diana Ernst. (2024) Update zum Sjögren-Syndrom: Diagnostik & Therapie. Aktuelle Rheumatologie.
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Xuan Cai, Ruo‐Yun Gui, Jin Wu, Chen‐Cong Wang, Xiao‐Lu Zhu, Hai‐Xia Fu & Xiao‐Hui Zhang. (2024) Decreased Expression of IL‐35 and Its Receptor Contributes to Impaired Megakaryopoiesis in the Pathogenesis of Immune Thrombocytopenia. Advanced Science 11:12.
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Liuting Zeng, Qi He, Ying Deng, Yuwei Li, Junpeng Chen, Kailin Yang, Yanfang Luo, Anqi Ge, Xiaofei Zhu, Zhiyong Long & Lingyun Sun. (2023) Efficacy and safety of iguratimod in the treatment of rheumatic and autoimmune diseases: a meta-analysis and systematic review of 84 randomized controlled trials. Frontiers in Pharmacology 14.
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Shuying Wang, Jiake Yu, Jie Yang, Yan Ge & Jing Tian. (2023) Effects of iguratimod on inflammatory factors and apoptosis of submandibular gland epithelial cells in NOD mice. Scientific Reports 13:1.
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Taibiao Lyu, Hui Jiang, Liuting Zeng, Suying Liu, Chengmei He, Chaowen Luo, Lin Qiao, Yan Zhao & Hua Chen. (2023) Iguratimod suppresses Tfh cell differentiation in primary Sjögren’s syndrome patients through inhibiting Akt/mTOR/STAT3 signaling. Arthritis Research & Therapy 25:1.
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Xiaoyan Wang, Xiang Lin, Yingying Su & Hao Wang. (2023) Systematic review with meta-analysis: Efficacy and safety of biological treatment on salivary gland function in primary Sjögren’s syndrome. Frontiers in Pharmacology 14.
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Jacob Ritter, Yidan Chen, Ana-Luisa Stefanski & Thomas Dörner. (2022) Current and future treatment in primary Sjögren's syndrome – A still challenging development. Joint Bone Spine 89:6, pages 105406.
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Jacob Ritter, Yidan Chen, Ana-Luisa Stefanski & Thomas Dörner. (2022) Traitements actuels et futurs du Syndrome de Sjögren primitif – un développement ambitieux. Revue du Rhumatisme 89:5, pages 465-473.
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Zhen Tan, Li Wang & Xiaomei Li. (2022) Composition and regulation of the immune microenvironment of salivary gland in Sjögren’s syndrome. Frontiers in Immunology 13.
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Liuting Zeng, Qi He, Kailin Yang, Wensa Hao, Ganpeng Yu & Hua Chen. (2022) A Systematic Review and Meta-Analysis of 19 Randomized Controlled Trials of Iguratimod Combined With Other Therapies for Sjogren’s Syndrome. Frontiers in Immunology 13.
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Jun Tao, Li Sun, Zijie Wang, Hao Chen, Zhijian Han, Hengcheng Zhang, Haiwei Yang, Zhengkai Huang, Shuang Fei, Xiaobin Ju, Ruoyun Tan & Min Gu. (2021) Efficacy and Safety of Iguratimod Supplement to the Standard Immunosuppressive Regimen in Highly Mismatched Renal Transplant Recipients: A Pilot Study. Frontiers in Immunology 12.
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Jincheng Pu, Xuan Wang, Farooq Riaz, Tongyangzi Zhang, Ronglin Gao, Shengnan Pan, Zhenzhen Wu, Yuanyuan Liang, Shuqi Zhuang & Jianping Tang. (2021) Effectiveness and Safety of Iguratimod in Treating Primary Sjögren’s Syndrome: A Systematic Review and Meta-Analysis. Frontiers in Pharmacology 12.
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Joyce J.B.C. van Beers & Jan G.M.C. Damoiseaux. (2021) Immune Monitoring upon Treatment with Biologics in Sjögren’s Syndrome: The What, Where, When, and How. Biomolecules 11:1, pages 116.
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