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Focused Reviews in CML

BCR/ABL, DNA damage and DNA repair: Implications for new treatment concepts

Pages 610-614 | Published online: 01 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Ikhwan Rinaldi & Kevin Winston. (2023) Chronic Myeloid Leukemia, from Pathophysiology to Treatment-Free Remission: A Narrative Literature Review. Journal of Blood Medicine 14, pages 261-277.
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Jadwiga Filipek-Gorzała, Patrycja Kwiecińska, Agata Szade & Krzysztof Szade. (2024) The dark side of stemness – the role of hematopoietic stem cells in development of blood malignancies. Frontiers in Oncology 14.
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Rachid Lahlil, Anne Aries, Maurice Scrofani, Céline Zanetti, Desline Hennequin & Bernard Drénou. (2023) Stem Cell Responsiveness to Imatinib in Chronic Myeloid Leukemia. International Journal of Molecular Sciences 24:23, pages 16671.
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Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Raquel Carvalho Montenegro, Maria Elisabete Amaral de Moraes & Caroline Aquino Moreira-Nunes. 2023. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Geoffrey Brown. (2022) Hematopoietic and Chronic Myeloid Leukemia Stem Cells: Multi-Stability versus Lineage Restriction. International Journal of Molecular Sciences 23:21, pages 13570.
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Yang Liang, Yuefeng Qin, Guoyun Jiang, Wenli Feng & Ying Yuan. (2022) Targeting MDC1 promotes apoptosis and sensitizes Imatinib resistance in CML cells by mainly disrupting non-homologous end-joining repair. Medical Oncology 39:12.
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Bilal Abdulmawjood, Beatriz Costa, Catarina Roma-Rodrigues, Pedro V. Baptista & Alexandra R. Fernandes. (2021) Genetic Biomarkers in Chronic Myeloid Leukemia: What Have We Learned So Far?. International Journal of Molecular Sciences 22:22, pages 12516.
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Trisiani Affandi, Angela M. Ohm, Dany Gaillard, Ami Haas & Mary E. Reyland. (2021) Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double-strand break repair. Journal of Biological Chemistry 296, pages 100401.
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Naranie Shanmuganathan, Bradley Chereda & Junia V. Melo. 2021. Chronic Myeloid Leukemia. Chronic Myeloid Leukemia 17 36 .
Ayca Kiykim, Nursah Eker, Ozlem Surekli, Ercan Nain, Nurhan Kasap, Hacer Aktürk, Omer Dogru, Aylin Canbolat, Ayper Somer, Ahmet Koc, Gulnur Tokuc, Suheyla Bozkurt, Kemal Turkoz, Elif Karakoc‐Aydiner, Ahmet Ozen & Safa Baris. (2019) Malignancy and lymphoid proliferation in primary immune deficiencies; hard to define, hard to treat. Pediatric Blood & Cancer 67:2.
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Mariam Ammar, Lobna Ben Mahmoud, Moez Medhaffar, Hanen Ghozzi, Zouheir Sahnoun, Ahmed Hakim, Malek Mseddi, Moez Elloumi & Khaled Zeghal. (2019) Relationship of oxidative stress in the resistance to imatinib in Tunisian patients with chronic myeloid leukemia: A retrospective study. Journal of Clinical Laboratory Analysis 34:2.
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Jules J. Berman. 2020. Logic and Critical Thinking in the Biomedical Sciences. Logic and Critical Thinking in the Biomedical Sciences 225 270 .
Çiğdem AYDIN ACAR, Zafer ÇETİN, Orhan Kemal YÜCEL, Utku ILTAR, Ozan SALİM & Sibel BERKER KARAÜZÜM. (2019) Kronik Myeloid Lösemide Tanı Anında İlave Kromozomal Abnormaliteler ve Varyant Philadephia Translokasyonları; Tek Merkez Deneyimi. SDÜ Tıp Fakültesi Dergisi 26:3, pages 320-327.
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Vivek Kumar, Mohit Garg, Neha Chaudhary & Abhinav Binod Chandra. (2018) An observational study on risk of secondary cancers in chronic myeloid leukemia patients in the TKI era in the United States. PeerJ 6, pages e4342.
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Qian Li, Xiao‑Ji Lin, Hui Chen, Jian Gong, Zhen Li & Xiang‑Nan Chen. (2018) Co-existence of isodicentric Ph chromosomes and the three-way Ph chromosome variant t(3;9;22)(p21;q34;q11) in a rare case of chronic myeloid leukemia. Oncology Letters.
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Akbar SafaeiAhmad MonabatiMoeinadin SafaviAli AtashabparvarMarzieh Hosseini. (2018) Additional cytogenetic aberrations in chronic myeloid leukemia: a single-center experience in the Middle East. Blood Research 53:1, pages 49.
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Tessa L. Holyoake & David Vetrie. (2017) The chronic myeloid leukemia stem cell: stemming the tide of persistence. Blood 129:12, pages 1595-1606.
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Victor Constantin Diculescu & Ana Maria Oliveira-Brett. (2016) In situ electrochemical evaluation of dsDNA interaction with the anticancer drug danusertib nitrenium radical product using the DNA-electrochemical biosensor. Bioelectrochemistry 107, pages 50-57.
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Bradley Chereda & Junia V. Melo. 2016. Chronic Myeloid Leukemia. Chronic Myeloid Leukemia 17 39 .
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Bradley Chereda & Junia V. Melo. (2015) Natural course and biology of CML. Annals of Hematology 94:S2, pages 107-121.
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Stefan K. Bohlander & Purvi M. Kakadia. 2015. Chromosomal Instability in Cancer Cells. Chromosomal Instability in Cancer Cells 1 37 .
Julieta Politi & Neil P. Shah. (2014) What Does a Deep Molecular Response Signify?. Journal of Clinical Oncology 32:5, pages 471-474.
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Marilia Borges Moreira, Caio Robledo DC Quaio, Aline Cristina Zandoná-Teixeira, Gil Monteiro Novo-Filho, Evelin Aline Zanardo, Leslie Domenici Kulikowski & Chong Ae Kim. (2013) Discrepant outcomes in two Brazilian patients with Bloom syndrome and Wilms’ tumor: two case reports. Journal of Medical Case Reports 7:1.
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Yajuan Li, Xi Chen, Meng Shi, Haixia Wang, Weixi Cao, Xiaozhong Wang, Chunli Li & Wenli Feng. (2013) Proteomic-based identification of Apg-2 as a therapeutic target for chronic myeloid leukemia. Cellular Signalling 25:12, pages 2604-2612.
Crossref
N L Pannucci, D Li, S Sahay, E K Thomas, R Chen, I Tala, T Hu, B T Ciccarelli, N J Megjugorac, H C Adams III, P L Rodriguez, E R Fitzpatrick, D Lagunoff, D A Williams & I P Whitehead. (2013) Loss of the xeroderma pigmentosum group B protein binding site impairs p210 BCR/ABL1 leukemogenic activity. Blood Cancer Journal 3:8, pages e135-e135.
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Giuseppe Saglio & Carmen FavaGiovanna Rege-Cambrin, Emilia Giugliano & Patrizia Scaravaglio. 2013. The Treatment of Chronic Myeloid Leukemia. The Treatment of Chronic Myeloid Leukemia 20 36 .
Marcello Maresca, Victor Guosheng Lin, Ning Guo & Yi Yang. (2013) Obligate Ligation-Gated Recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining. Genome Research 23:3, pages 539-546.
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Linda M. Scott & Vivienne I. Rebel. (2012) JAK2 and genomic instability in the myeloproliferative neoplasms: A case of the chicken or the egg?. American Journal of Hematology 87:11, pages 1028-1036.
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André L. Mencalha, Renata Binato, Gerson M. Ferreira, Barbara Du Rocher & Eliana Abdelhay. (2012) Forkhead Box M1 (FoxM1) Gene Is a New STAT3 Transcriptional Factor Target and Is Essential for Proliferation, Survival and DNA Repair of K562 Cell Line. PLoS ONE 7:10, pages e48160.
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Monika Kusio-Kobialka, Kamila Wolanin, Paulina Podszywalow-Bartnicka, Ewa Sikora, Krzysztof Skowronek, Sharon L. McKenna, Massimo Ghizzoni, Frank J. Dekker & Katarzyna Piwocka. (2012) Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage. Apoptosis 17:9, pages 950-963.
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Tomasz Skorski. (2012) Genetic Mechanisms of Chronic Myeloid Leukemia Blastic Transformation. Current Hematologic Malignancy Reports 7:2, pages 87-93.
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Kwong‐Fai Wong, Yi Yuan & John M Luk. (2012) Tripterygium wilfordii bioactive compounds as anticancer and anti‐inflammatory agents . Clinical and Experimental Pharmacology and Physiology 39:3, pages 311-320.
Crossref
Wen Chun Juan & S. Tiong Ong. 2012. Protein Phosphorylation in Health and Disease. Protein Phosphorylation in Health and Disease 107 142 .
Andrew Coveler & Vivian G. Oehler. 2012. Leukemia and Related Disorders. Leukemia and Related Disorders 97 147 .
Alice FabariusArmin LeitnerAndreas HochhausMartin C. MüllerBenjamin HanfsteinClaudia HaferlachGudrun GöhringBrigitte SchlegelbergerMartine JotterandAndreas ReiterSusanne Jung-MunkwitzUlrike ProetelJuliana SchwaabWolf-Karsten HofmannJörg SchubertHermann EinseleAnthony D. HoChristiane FalgeLothar KanzAndreas NeubauerMichael KnebaFrank StegelmannMichael PfreundschuhCornelius F. WallerKarsten SpiekermannGabriela M. Baerlocher, Michael Lauseker, Markus Pfirrmann, Joerg Hasford, Susanne SausseleRüdiger Hehlmann. (2011) Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV. Blood 118:26, pages 6760-6768.
Crossref
Rita Colnaghi, Gillian Carpenter, Marcel Volker & Mark O’Driscoll. (2011) The consequences of structural genomic alterations in humans: Genomic Disorders, genomic instability and cancer. Seminars in Cell & Developmental Biology 22:8, pages 875-885.
Crossref
Jerald P. Radich. (2011) The Biology of Chronic Myelogenous Leukemia Progression: Who, What, Where, and Why?. Hematology/Oncology Clinics of North America 25:5, pages 967-980.
Crossref
Elias JabbourJorge CortesFabio P. S. SantosDan Jones, Susan O'BrienGabriela Rondon, Uday Popat, Sergio Giralt, Partow Kebriaei, Roy B. Jones, Hagop KantarjianRichard Champlin & Marcos de Lima. (2011) Results of allogeneic hematopoietic stem cell transplantation for chronic myelogenous leukemia patients who failed tyrosine kinase inhibitors after developing BCR-ABL1 kinase domain mutations. Blood 117:13, pages 3641-3647.
Crossref
Henning D. Popp & Stefan K. Bohlander. (2010) Genetic instability in inherited and sporadic leukemias. Genes, Chromosomes and Cancer 49:12, pages 1071-1081.
Crossref
I Sloma, X Jiang, A C Eaves & C J Eaves. (2010) Insights into the stem cells of chronic myeloid leukemia. Leukemia 24:11, pages 1823-1833.
Crossref
Danilo Perrotti, Catriona Jamieson, John Goldman & Tomasz Skorski. (2010) Chronic myeloid leukemia: mechanisms of blastic transformation. Journal of Clinical Investigation 120:7, pages 2254-2264.
Crossref
B A Burke & M Carroll. (2010) BCR–ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia. Leukemia 24:6, pages 1105-1112.
Crossref
Mirle SchemionekChristian EllingUlrich SteidlNicole BäumerAshley HamiltonTilmann SpiekerJoachim R. GöthertMartin StehlingAmy WagersClaudia S. HuettnerDaniel G. TenenLara Tickenbrock, Wolfgang E. BerdelHubert Serve, Tessa L. HolyoakeCarsten Müller-TidowSteffen Koschmieder. (2010) BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells. Blood 115:16, pages 3185-3195.
Crossref
Philipp le Coutre, Michaela Schwarz & Theo D. Kim. (2010) New Developments in Tyrosine Kinase Inhibitor Therapy for Newly Diagnosed Chronic Myeloid Leukemia. Clinical Cancer Research 16:6, pages 1771-1780.
Crossref
A Slupianek, S K Jozwiakowski, E Gurdek & T Skorski. (2009) BCR/ABL kinase interacts with and phosphorylates the RAD51 paralog, RAD51B. Leukemia 23:12, pages 2308-2310.
Crossref

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