Citations (21)
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Haishan Li & Hongbing Wang. (2010) Activation of xenobiotic receptors: driving into the nucleus. Expert Opinion on Drug Metabolism & Toxicology 6:4, pages 409-426.
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N. Plant & S. Aouabdi. (2009) Nuclear receptors: the controlling force in drug metabolism of the liver?. Xenobiotica 39:8, pages 597-605.
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Michael Murray. (2007) Role of signalling systems in the effects of dietary factors on the expression of mammalian CYPs. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 185-196.
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Articles from other publishers (18)
Lyubov S. Klyushova, Maria L. Perepechaeva & Alevtina Y. Grishanova. (2022) The Role of CYP3A in Health and Disease. Biomedicines 10:11, pages 2686.
Crossref
Crossref
Tomas Smutny, Lucie Hyrsova, Albert Braeuning, Magnus Ingelman-Sundberg & Petr Pavek. (2020) Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism. Archives of Toxicology 95:1, pages 11-25.
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Crossref
Tomas Smutny, Jan Dusek, Lucie Hyrsova, Jana Nekvindova, Alzbeta Horvatova, Stanislav Micuda, Sabine Gerbal-Chaloin & Petr Pavek. (2020) The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids. Acta Pharmaceutica Sinica B 10:1, pages 136-152.
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Jurjen Duintjer Tebbens, Malek Azar, Elfriede Friedmann, Martin Lanzendörfer & Petr Pávek. (2018) Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction. International Journal of Molecular Sciences 19:6, pages 1785.
Crossref
Crossref
X. Ding & Q-Y. Zhang. 2018. Comprehensive Toxicology. Comprehensive Toxicology
8
44
.
Elaina M. Maldonado, Vytautas Leoncikas, Ciarán P. Fisher, J. Bernadette Moore, Nick J. Plant & Andrzej M. Kierzek. (2017) Integration of Genome Scale Metabolic Networks and Gene Regulation of Metabolic Enzymes With Physiologically Based Pharmacokinetics. CPT: Pharmacometrics & Systems Pharmacology 6:11, pages 732-746.
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Alexey Kolodkin, Nilgun Sahin, Anna Phillips, Steve R. Hood, Frank J. Bruggeman, Hans V. Westerhoff & Nick Plant. (2013) Optimization of stress response through the nuclear receptor-mediated cortisol signalling network. Nature Communications 4:1.
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Ian Bailey, G. Gordon Gibson, Kathryn Plant, Mark Graham & Nick Plant. (2011) A PXR-Mediated Negative Feedback Loop Attenuates the Expression of CYP3A in Response to the PXR Agonist Pregnenalone-16α-Carbonitrile. PLoS ONE 6:2, pages e16703.
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Lynne Shanley, Scott Davidson, Marissa Lear, Anil Kumar Thotakura, Iain Joseph McEwan, Ruth A. Ross & Alasdair MacKenzie. (2010) Long-Range Regulatory Synergy Is Required to Allow Control of the TAC1 Locus by MEK/ERK Signalling in Sensory Neurones. Neurosignals 18:3, pages 173-185.
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X. Ding & Q.-Y. Zhang. 2010. Comprehensive Toxicology. Comprehensive Toxicology
9
29
.
Stefanie D. Krämer & Bernard Testa. (2009) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 6:10, pages 1477-1660.
Crossref
Crossref
Nick Plant. (2008) Can systems toxicology identify common biomarkers of non-genotoxic carcinogenesis?. Toxicology 254:3, pages 164-169.
Crossref
Crossref
Jatinder Lamba & Erin G. Schuetz. 2008. Nuclear Receptors in Drug Metabolism. Nuclear Receptors in Drug Metabolism
241
273
.
I.S. Haslam, K. Jones, T. Coleman & N.L. Simmons. (2008) Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84). Biochemical Pharmacology 76:7, pages 850-861.
Crossref
Crossref
I S Haslam, K Jones, T Coleman & N L Simmons. (2009) Rifampin and digoxin induction of MDR1 expression and function in human intestinal (T84) epithelial cells. British Journal of Pharmacology 154:1, pages 246-255.
Crossref
Crossref
P Martin, R Riley, D J Back & A Owen. (2009) Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. British Journal of Pharmacology 153:4, pages 805-819.
Crossref
Crossref
Shirley Teng & Micheline Piquette-Miller. (2007) Regulation of Transporters by Nuclear Hormone Receptors: Implications during Inflammation. Molecular Pharmaceutics 5:1, pages 67-76.
Crossref
Crossref
Jatinder Lamba, Vishal Lamba, Stephen Strom, Raman Venkataramanan & Erin Schuetz. (2008) Novel Single Nucleotide Polymorphisms in the Promoter and Intron 1 of Human Pregnane X Receptor/NR1I2 and Their Association with CYP3A4 Expression. Drug Metabolism and Disposition 36:1, pages 169-181.
Crossref
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