Citations (30)
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Christina N Kontoghiorghe, Annita Kolnagou & George J Kontoghiorghes. (2013) Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals. Expert Opinion on Investigational Drugs 22:5, pages 591-618.
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Annita Kolnagou, Konstantinos Natsiopoulos, Marios Kleanthous, Alexia Ioannou & George J. Kontoghiorghes. (2013) Liver iron and serum ferritin levels are misleading for estimating cardiac, pancreatic, splenic and total body iron load in thalassemia patients: factors influencing the heterogenic distribution of excess storage iron in organs as identified by MRI T2*. Toxicology Mechanisms and Methods 23:1, pages 48-56.
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Annita Kolnagou, Marios Kleanthous & George J. Kontoghiorghes. (2011) Efficacy, Compliance And Toxicity Factors Are Affecting The Rate Of Normalization Of Body Iron Stores In Thalassemia Patients Using The Deferiprone And Deferoxamine Combination Therapy. Hemoglobin 35:3, pages 186-198.
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Annita Kolnagou & George J. Kontoghiorghes. (2010) Maintenance of Normal Range Body Iron Store Levels for up to 4.5 Years in Thalassemia Major Patients Using Deferiprone Monotherapy. Hemoglobin 34:3, pages 204-209.
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Dimitrios Tsiapras, Soso Fragatou, Kalistheni Farmaki, Stamatios Kyrzopoulos, Ioannis Paraskevaidis, Vasilios Voudris & Dimitrios Kremastinos. (2010) Effect of Combined Chelation Therapy with Deferiprone and Deferoxamine on Left Ventricular Diastolic Function in Adult β-Thalassemia Major Patients. Hemoglobin 34:3, pages 210-220.
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George J. Kontoghiorghes. (2010) The 18th ICOC Proceedings in Athens, Greece: New Breakthrough in Thalassemia Leading to the Complete Treatment of Iron Overload and to Hundreds of Patients Achieving and Maintaining Normal Body Iron Stores. Ethical Questions on Chelation Therapy. Hemoglobin 34:3, pages 199-203.
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G J Kontoghiorghes, A Kolnagou, C-T Peng, S V Shah & A Aessopos. (2010) Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases. Expert Opinion on Drug Safety 9:2, pages 201-206.
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George J. Kontoghiorghes. (2009) A New Era in Iron Chelation Therapy: The Design of Optimal, Individually Adjusted Iron Chelation Therapies for the Complete Removal of Iron Overload in Thalassemia and other Chronically Transfused Patients. Hemoglobin 33:5, pages 332-338.
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George J. Kontoghiorghes, Aglaia Efstathiou, Marios Kleanthous, Yiannis Michaelides & Anita Kolnagou. (2009) Risk/Benefit Assessment, Advantages Over Other Drugs and Targeting Methods in the Use of Deferiprone as a Pharmaceutical Antioxidant in Iron Loading and Non Iron Loading Conditions. Hemoglobin 33:5, pages 386-397.
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Anita Kolnagou & George J. Kontoghiorghes. (2009) Advances in the Prevention and Treatment are Changing Thalassemia from a Fatal to a Chronic Disease. Experience from a Cyprus Model and its Use as a Paradigm for Future Applications. Hemoglobin 33:5, pages 287-295.
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George J. Kontoghiorghes. (2008) Transparency and Access to Full Information for the Fatal or Serious Toxicity Risks, Low Efficacy and High Price of Deferasirox, Could Increase the Prospect of Improved Iron Chelation Therapy Worldwide. Hemoglobin 32:6, pages 608-615.
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Articles from other publishers (19)
George J. Kontoghiorghes. (2023) Drug Selection and Posology, Optimal Therapies and Risk/Benefit Assessment in Medicine: The Paradigm of Iron-Chelating Drugs. International Journal of Molecular Sciences 24:23, pages 16749.
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George J. Kontoghiorghes. (2023) Iron Load Toxicity in Medicine: From Molecular and Cellular Aspects to Clinical Implications. International Journal of Molecular Sciences 24:16, pages 12928.
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George J. Kontoghiorghes. (2023) The Vital Role Played by Deferiprone in the Transition of Thalassaemia from a Fatal to a Chronic Disease and Challenges in Its Repurposing for Use in Non-Iron-Loaded Diseases. Pharmaceuticals 16:7, pages 1016.
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George J. Kontoghiorghes. (2022) New Iron Metabolic Pathways and Chelation Targeting Strategies Affecting the Treatment of All Types and Stages of Cancer. International Journal of Molecular Sciences 23:22, pages 13990.
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Cecilia H. Kim & Heather A. Leitch. (2021) Iron overload-induced oxidative stress in myelodysplastic syndromes and its cellular sequelae. Critical Reviews in Oncology/Hematology 163, pages 103367.
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I. Tong Mak, Jay H. Kramer, Micaela Iantorno, Joanna J. Chmielinska, William B. Weglicki & Christopher F. Spurney. (2020) Deficiency in gp91Phox (NOX2) Protects against Oxidative Stress and Cardiac Dysfunction in Iron Overloaded Mice. Hearts 1:2, pages 117-125.
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George J. Kontoghiorghes, Annita Kolnagou, Christina N. Kontoghiorghe, Loukia Mourouzidis, Viktor A. Timoshnikov & Nikolay E. Polyakov. (2020) Trying to Solve the Puzzle of the Interaction of Ascorbic Acid and Iron: Redox, Chelation and Therapeutic Implications. Medicines 7:8, pages 45.
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Pawan Sharma, Krishan Gopal Jain, Pulak M. Pandey & Sujata Mohanty. (2020) In vitro degradation behaviour, cytocompatibility and hemocompatibility of topologically ordered porous iron scaffold prepared using 3D printing and pressureless microwave sintering. Materials Science and Engineering: C 106, pages 110247.
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Colleen A.C. Wong & Heather A. Leitch. (2019) Delayed time from RBC transfusion dependence to first cardiac event in lower IPSS risk MDS patients receiving iron chelation therapy. Leukemia Research 83, pages 106170.
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Yuki Honda, Tetsu Watanabe, Yoichiro Otaki, Harutoshi Tamura, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Tetsuro Shishido, Takuya Miyamoto, Yoko Shibata, Tsuneo Konta, Ryo Kawasaki, Makoto Daimon, Yoshiyuki Ueno, Takeo Kato, Takamasa Kayama & Isao Kubota. (2018) Gender differences in the impact of anemia on subclinical myocardial damage and cardiovascular mortality in the general population: The Yamagata (Takahata) study. International Journal of Cardiology 252, pages 207-212.
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Christina N Kontoghiorghe & George J Kontoghiorghes. (2016) New developments and controversies in iron metabolism and iron chelation therapy. World Journal of Methodology 6:1, pages 1.
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Annita Kolnagou. (2014) Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases. World Journal of Methodology 4:4, pages 197.
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Chanita Sanyear, Punnee Butthep, Ramaneeya Nithipongvanich, Pornpan Sirankapracha, Pranee Winichagoon, Suthat Fucharoen & Saovaros Svasti. (2013) Cardiomyocyte ultrastructural damage in β-thalassaemic mice. International Journal of Experimental Pathology 94:5, pages 336-342.
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Annita Kolnagou, Marios Kleanthous & George J. Kontoghiorghes. (2010) Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy. European Journal of Haematology 85:5, pages 430-438.
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Brandon J. Reeder. (2010) The Redox Activity of Hemoglobins: From Physiologic Functions to Pathologic Mechanisms. Antioxidants & Redox Signaling 13:7, pages 1087-1123.
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Erlin Zhang, Haiyan Chen & Feng Shen. (2010) Biocorrosion properties and blood and cell compatibility of pure iron as a biodegradable biomaterial. Journal of Materials Science: Materials in Medicine 21:7, pages 2151-2163.
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Annita Kolnagou & George J. Kontoghiorghes. (2010) New golden era of chelation therapy in thalassaemia: the achievement and maintenance of normal range body iron stores. British Journal of Haematology, pages no-no.
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Paul W. BuehlerFelice D'Agnillo. (2010) Toxicological Consequences of Extracellular Hemoglobin: Biochemical and Physiological Perspectives. Antioxidants & Redox Signaling 12:2, pages 275-291.
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Tatiana Yu. Karogodina, Svetlana V. Sergeeva & Dmitri V. Stass. (2009) Magnetic Field Effect in the Reaction of Recombination of Nitric Oxide and Superoxide Anion. Applied Magnetic Resonance 36:2-4, pages 195-208.
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