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Hemoglobin
international journal for hemoglobin research
Volume 32, 2008 - Issue 1-2
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Original

Long Term Comparative Studies in Thalassemia Patients Treated with Deferoxamine or a Deferoxamine/Deferiprone Combination. Identification of Effective Chelation Therapy Protocols

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Pages 41-47 | Published online: 07 Jul 2009

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Ahmed Saleh Ibrahim, Azza Hasan Abd El-Fatah, Ayman Fathy Abd El-Halim & Farid Fawzy Mohamed. (2023) Serum Ferritin Levels and Other Associated Parameters with Diabetes Mellitus in Adult Patients Suffering from Beta Thalassemia Major. Journal of Blood Medicine 14, pages 67-81.
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Zeynep Canan Ozdemir, Ahmet Koc, Ali Aycicek & Abdurrahim Kocyigit. (2014) N-Acetylcysteine Supplementation Reduces Oxidative Stress and DNA Damage in Children with β-Thalassemia. Hemoglobin 38:5, pages 359-364.
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Ali T Taher, Sally Temraz & M Domenica Cappellini. (2013) Deferasirox for the treatment of iron overload in non-transfusion-dependent thalassemia. Expert Review of Hematology 6:5, pages 495-509.
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Christina N Kontoghiorghe, Annita Kolnagou & George J Kontoghiorghes. (2013) Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals. Expert Opinion on Investigational Drugs 22:5, pages 591-618.
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Annita Kolnagou, Yiannis Michaelides, Christina N. Kontoghiorghe & George J. Kontoghiorghes. (2013) The importance of spleen, spleen iron, and splenectomy for determining total body iron load, ferrikinetics, and iron toxicity in thalassemia major patients. Toxicology Mechanisms and Methods 23:1, pages 34-41.
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Shau-Yin Ha, Amanda Sio-Peng Mok, Winnie Chiu-Wing Chu, Darshana Dattatray Rasalkar, Daniel Ka-Leung Cheuk, Alan Kwok-Shing Chiang, Marco Hok-Kung Ho & Godfrey Chi-Fung Chan. (2011) Intermediate-Term Evaluation Of A Pratical Chelation Protocol Based On Stratification Of Thalassemic Patients By Serum Ferritin And Magnetic Resonance Imaging Cardiac T2*. Hemoglobin 35:3, pages 199-205.
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George J. Kontoghiorghes, Annita Kolnagou, Anna Skiada & George Petrikkos. (2010) The Role of Iron and Chelators on Infections in Iron Overload and Non Iron Loaded Conditions: Prospects for the Design of New Antimicrobial Therapies. Hemoglobin 34:3, pages 227-239.
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G J Kontoghiorghes, A Kolnagou, C-T Peng, S V Shah & A Aessopos. (2010) Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases. Expert Opinion on Drug Safety 9:2, pages 201-206.
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Eleni E. Drakonaki, Thomas G. Maris, Stella Maragaki, Vaggelis Klironomos, Alex Papadakis & Apostolos H. Karantanas. (2010) Deferoxamine Versus Combined Therapy for Chelating Liver, Spleen and Bone Marrow Iron in β-Thalassemic Patients: A Quantitative Magnetic Resonance Imaging Study. Hemoglobin 34:1, pages 95-106.
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Articles from other publishers (27)

George J. Kontoghiorghes. (2023) Drug Selection and Posology, Optimal Therapies and Risk/Benefit Assessment in Medicine: The Paradigm of Iron-Chelating Drugs. International Journal of Molecular Sciences 24:23, pages 16749.
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Louise J Geneen, Carolyn Dorée & Lise J Estcourt. (2023) Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia. Cochrane Database of Systematic Reviews 2023:3.
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George J. Kontoghiorghes. (2023) Deferiprone and Iron–Maltol: Forty Years since Their Discovery and Insights into Their Drug Design, Development, Clinical Use and Future Prospects. International Journal of Molecular Sciences 24:5, pages 4970.
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Sarina Entezari, Seyedeh Mona Haghi, Narges Norouzkhani, Barsa Sahebnazar, Fatemeh Vosoughian, Diba Akbarzadeh, Muhammad Islampanah, Navid Naghsh, Mohammad Abbasalizadeh & Niloofar Deravi. (2022) Iron Chelators in Treatment of Iron Overload. Journal of Toxicology 2022, pages 1-18.
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George Kontoghiorghes & Christina Kontoghiorghe. (2020) Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases. Cells 9:6, pages 1456.
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Nancy F. Olivieri, Amir Sabouhanian & Brenda L. Gallie. (2019) Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox. PLOS ONE 14:2, pages e0211942.
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Mukul Aggarwal, Sumeet Mirgh, Deepak Bansal & Sidharth Totadri. (2018) Editorial. Indian Pediatrics 55:7, pages 557-560.
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Patricia M Fortin, Sheila A Fisher, Karen V Madgwick, Marialena Trivella, Sally Hopewell, Carolyn Doree & Lise J Estcourt. (2018) Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia. Cochrane Database of Systematic Reviews 2018:5.
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Sophie Mavrogeni, Genovefa Kolovou, Boris Bigalke, Angelos Rigopoulos, Michel Noutsias & Stamatis Adamopoulos. (2018) Transplantation in patients with iron overload: is there a place for magnetic resonance imaging?. Heart Failure Reviews 23:2, pages 173-180.
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Claudia Bollig, Lisa K Schell, Gerta Rücker, Roman Allert, Edith Motschall, Charlotte M Niemeyer, Dirk Bassler & Joerg J Meerpohl. (2017) Deferasirox for managing iron overload in people with thalassaemia. Cochrane Database of Systematic Reviews 2017:8.
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Hamid Farhangi, Zahra Badiei, Hasan Mottaghi Moghaddam & Mohammad Reza Keramati. (2016) Assessment of Heart and Liver Iron Overload in Thalassemia Major Patients Using T2* Magnetic Resonance Imaging. Indian Journal of Hematology and Blood Transfusion 33:2, pages 228-234.
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Christina N Kontoghiorghe & George J Kontoghiorghes. (2016) New developments and controversies in iron metabolism and iron chelation therapy. World Journal of Methodology 6:1, pages 1.
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Emmanouil Petrou, Sophie Mavrogeni, Vasiliki Karali, Genovefa Kolovou, Marie-Christine Kyrtsonis, Petros P. Sfikakis & Panayiotis Panayiotidis. (2015) The role of magnetic resonance imaging in the evaluation of transfusional iron overload in myelodysplastic syndromes. Revista Brasileira de Hematologia e Hemoterapia 37:4, pages 252-258.
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Joerg J Meerpohl, Lisa K Schell, Gerta Rücker, Nigel Fleeman, Edith Motschall, Charlotte M Niemeyer & Dirk Bassler. (2014) Deferasirox for managing iron overload in people with myelodysplastic syndrome. Cochrane Database of Systematic Reviews 2014:10.
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Sophie Mavrogeni, George Markousis-Mavrogenis & Genovefa Kolovou. (2014) The Role of Magnetic Resonance Imaging in the Evaluation of Thalassemic Syndromes: Current Practice and Future Perspectives. Thalassemia Reports 4:2, pages 1859.
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Joerg J Meerpohl, Lisa K Schell, Gerta Rücker, Edith Motschall, Nigel Fleeman, Charlotte M Niemeyer & Dirk Bassler. (2014) Deferasirox for managing transfusional iron overload in people with sickle cell disease. Cochrane Database of Systematic Reviews 2017:6.
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Annita Kolnagou. (2014) Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases. World Journal of Methodology 4:4, pages 197.
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Christina N Kontoghiorghe. (2014) World health dilemmas: Orphan and rare diseases, orphan drugs and orphan patients. World Journal of Methodology 4:3, pages 163.
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Joerg J Meerpohl, Gerd Antes, Gerta Rücker, Nigel Fleeman, Edith Motschall, Charlotte M Niemeyer & Dirk Bassler. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Joerg J Meerpohl, Gerd Antes, Gerta Rücker, Nigel Fleeman, Edith Motschall, Charlotte M Niemeyer & Dirk Bassler. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Annita Kolnagou, Marios Kleanthous & George J. Kontoghiorghes. (2010) Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy. European Journal of Haematology 85:5, pages 430-438.
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Joerg J Meerpohl, Gerd Antes, Gerta Rücker, Nigel Fleeman, Charlotte M Niemeyer & Dirk Bassler. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Annita Kolnagou & George J. Kontoghiorghes. (2010) New golden era of chelation therapy in thalassaemia: the achievement and maintenance of normal range body iron stores. British Journal of Haematology 150:4, pages 489-490.
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Lauren E. Scott & Chris Orvig. (2009) Medicinal Inorganic Chemistry Approaches to Passivation and Removal of Aberrant Metal Ions in Disease. Chemical Reviews 109:10, pages 4885-4910.
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Joerg J Meerpohl, Gerd Antes, Gerta Rücker, Claire McLeod, Nigel Fleeman, Charlotte Niemeyer & Dirk Bassler. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Joerg J Meerpohl, Gerd Antes, Gerta Rücker, Claire McLeod, Nigel Fleeman, Charlotte M Niemeyer & Dirk Bassler. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Joerg J Meerpohl, Gerd Antes, Gerta Rücker, Claire McLeod, Nigel Fleeman, Charlotte Niemeyer & Dirk Bassler. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.

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