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Hemoglobin
international journal for hemoglobin research
Volume 32, 2008 - Issue 1-2
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Original

Chelators Controlling Metal Metabolism and Toxicity Pathways: Applications in Cancer Prevention, Diagnosis and Treatment

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Pages 217-227 | Published online: 07 Jul 2009

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Christina N Kontoghiorghe, Annita Kolnagou & George J Kontoghiorghes. (2013) Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals. Expert Opinion on Investigational Drugs 22:5, pages 591-618.
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Eleni Konstantinou, Ioannis Pashalidis, Annita Kolnagou & George J. Kontoghiorghes. (2011) Interactions Of Hydroxycarbamide (Hydroxyurea) With Iron And Copper: Implications On Toxicity and Therapeutic Strategies. Hemoglobin 35:3, pages 237-246.
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Hiroshi Kobayashi, Yoshihiko Yamada, Seiji Kanayama, Naoto Furukawa, Taketoshi Noguchi, Shoji Haruta, Shozo Yoshida, Mariko Sakata, Toshiyuki Sado & Hidekazu Oi. (2009) The role of iron in the pathogenesis of endometriosis. Gynecological Endocrinology 25:1, pages 39-52.
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George J. Kontoghiorghes. (2022) New Iron Metabolic Pathways and Chelation Targeting Strategies Affecting the Treatment of All Types and Stages of Cancer. International Journal of Molecular Sciences 23:22, pages 13990.
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Viktor A. Timoshnikov, Olga Yu. Selyutina, Nikolay E. Polyakov, Victoria Didichenko & George J. Kontoghiorghes. (2022) Mechanistic Insights of Chelator Complexes with Essential Transition Metals: Antioxidant/Pro-Oxidant Activity and Applications in Medicine. International Journal of Molecular Sciences 23:3, pages 1247.
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Daniel G.J. Smethurst & Natalia Shcherbik. (2021) Interchangeable utilization of metals: New perspectives on the impacts of metal ions employed in ancient and extant biomolecules. Journal of Biological Chemistry 297:6, pages 101374.
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George Kontoghiorghes, Annita Kolnagou, Theodora Demetriou, Marina Neocleous & Christina Kontoghiorghe. (2021) New Era in the Treatment of Iron Deficiency Anaemia Using Trimaltol Iron and Other Lipophilic Iron Chelator Complexes: Historical Perspectives of Discovery and Future Applications. International Journal of Molecular Sciences 22:11, pages 5546.
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George Kontoghiorghes & Christina Kontoghiorghe. (2020) Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases. Cells 9:6, pages 1456.
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Chunli Chen, Shicheng Wang & Ping Liu. (2019) Deferoxamine Enhanced Mitochondrial Iron Accumulation and Promoted Cell Migration in Triple-Negative MDA-MB-231 Breast Cancer Cells Via a ROS-Dependent Mechanism. International Journal of Molecular Sciences 20:19, pages 4952.
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A. Valizadeh & R. Ghiasi. (2017) Theoretical approach to the molecular structure, chemical reactivity, molecular orbital analysis, spectroscopic properties (IR, UV, NMR), and NBO analysis of deferiprone. Journal of Structural Chemistry 58:7, pages 1307-1317.
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Dongsheng Wang, Shifang Peng, A. R. M. Ruhul Amin, Mohammad Aminur Rahman, Sreenivas Nannapaneni, Yuan Liu, Dong M. Shin, Nabil F. Saba, Jack F. Eichler & Zhuo G. Chen. (2016) Antitumor Activity of 2,9-Di-Sec-Butyl-1,10-Phenanthroline. PLOS ONE 11:12, pages e0168450.
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Sarah Gibson, Rasika Fernando, Hollie K. Jacobs & Aravamudan S. Gopalan. (2015) Preparation of 3-benzyloxy-2-pyridinone functional linkers: tools for the synthesis of 3,2-hydroxypyridinone (HOPO) and HOPO/hydroxamic acid chelators. Tetrahedron 71:49, pages 9271-9281.
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ZHEN YANG, SUN YANG, BOBBYE J. MISNER, FENG LIU-SMITH & FRANK L. MEYSKENS. (2014) The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression. International Journal of Oncology 45:5, pages 1820-1828.
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Anne-Sophie Borowiec, Gabriel Bidaux & Thierry Capiod. 2013. Trends in Stem Cell Proliferation and Cancer Research. Trends in Stem Cell Proliferation and Cancer Research 65 92 .
Tengfei Zheng & Elizabeth M. Nolan. (2012) Siderophore-based detection of Fe(iii) and microbial pathogens. Metallomics 4:9, pages 866.
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Mithun Roy, Balabhadrapatruni V. S. K. Chakravarthi, Chelliah Jayabaskaran, Anjali A. Karande & Akhil R. Chakravarty. (2011) Impact of metal binding on the antitumor activity and cellular imaging of a metal chelator cationic imidazopyridine derivative. Dalton Transactions 40:18, pages 4855-4864.
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Kyu Kwang Kim, Thilo S Lange, Rakesh K Singh & Laurent Brard. (2010) Lipophilic aroylhydrazone chelator HNTMB and its multiple effects on ovarian cancer cells. BMC Cancer 10:1.
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James R. Connor & Sang Y. Lee. 2010. Bioactive Compounds and Cancer. Bioactive Compounds and Cancer 469 496 .
Erin E. Battin & Julia L. Brumaghim. (2009) Antioxidant Activity of Sulfur and Selenium: A Review of Reactive Oxygen Species Scavenging, Glutathione Peroxidase, and Metal-Binding Antioxidant Mechanisms. Cell Biochemistry and Biophysics 55:1, pages 1-23.
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Tadhg P. BegleyArindam Mukherjee & Peter J. Sadler. 2007. Wiley Encyclopedia of Chemical Biology. Wiley Encyclopedia of Chemical Biology.
Wang Gai Qing, Yang Qi Dong, Tang Qing Ping, Li Guang Lai, Li Dong Fang, Hu Wei Min, Lian Xia & Pei Yu Heng. (2009) Brain edema after intracerebral hemorrhage in rats: the role of iron overload and aquaporin 4. Journal of Neurosurgery 110:3, pages 462-468.
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