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Research Article

Tailoring the Release Rates of Fluconazole Using Solid Dispersions in Polymer Blends

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Pages 336-346 | Published online: 20 Oct 2008

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Sofia Papadimitriou & Dimitrios Bikiaris. (2009) Dissolution rate enhancement of the poorly water-soluble drug Tibolone using PVP, SiO2, and their nanocomposites as appropriate drug carriers. Drug Development and Industrial Pharmacy 35:9, pages 1128-1138.
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Articles from other publishers (29)

Asmaa M. El Shiekh Ali, Gamal M. El Maghraby, Abdelaziz E. Abdelaziz, Ahmed M. Soliman, Eman M. Saied & Eman A. Mazyed. (2023) Co-processing of fluconazole with menthol for enhanced dissolution and anti-fungal activity: Preparation of orodispersable tablets. Journal of Drug Delivery Science and Technology 88, pages 104937.
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Georgia Michailidou & Dimitrios N. Bikiaris. (2022) Novel 3D-Printed Dressings of Chitosan–Vanillin-Modified Chitosan Blends Loaded with Fluticasone Propionate for Treatment of Atopic Dermatitis. Pharmaceutics 14:9, pages 1966.
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Nikolaos D. Bikiaris, Ioanna Koumentakou, Georgia Michailidou, Margaritis Kostoglou, Marilena Vlachou, Panagiotis Barmpalexis, Evangelos Karavas & George Z. Papageorgiou. (2022) Investigation of Molecular Weight, Polymer Concentration and Process Parameters Factors on the Sustained Release of the Anti-Multiple-Sclerosis Agent Teriflunomide from Poly(ε-caprolactone) Electrospun Nanofibrous Matrices. Pharmaceutics 14:8, pages 1693.
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Gülsel Yurtdaş-Kırımlıoğlu. (2021) A promising approach to design thermosensitive in situ gel based on solid dispersions of desloratadine with Kolliphor® 188 and Pluronic® F127. Journal of Thermal Analysis and Calorimetry 147:2, pages 1307-1327.
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Georgia Michailidou, George Z. Papageorgiou & Dimitrios N. Bikiaris. (2021) β-Cyclodextrin Inclusion Complexes of Budesonide with Enhanced Bioavailability for COPD Treatment. Applied Sciences 11:24, pages 12085.
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Rongzhen Fang, Yan Liu, Lei Ma, Xiang Yu & Yiguang Jin. (2021) Facile preparation of solid dispersions by dissolving drugs in N-vinyl-2-pyrrolidone and photopolymerization. Materials Science and Engineering: C 124, pages 112063.
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Maria Francesca Di Filippo, Beatrice Albertini, Luisa Stella Dolci, Francesca Bonvicini, Adriana Bigi, Giovanna Angela Gentilomi, Nadia Passerini & Silvia Panzavolta. (2021) Novel drug-loaded film forming patch based on gelatin and snail slime. International Journal of Pharmaceutics 598, pages 120408.
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Keisuke Ueda & Lynne S. Taylor. (2021) Partitioning of surfactant into drug-rich nanodroplets and its impact on drug thermodynamic activity and droplet size. Journal of Controlled Release 330, pages 229-243.
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Nasser N. Nyamweya. (2021) Applications of polymer blends in drug delivery. Future Journal of Pharmaceutical Sciences 7:1.
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Nina Maria Ainali, Eleftheria Xanthopoulou, Georgia Michailidou, Alexandra Zamboulis & Dimitrios N. Bikiaris. (2020) Microencapsulation of Fluticasone Propionate and Salmeterol Xinafoate in Modified Chitosan Microparticles for Release Optimization. Molecules 25:17, pages 3888.
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Keisuke Ueda, Siddhi S. Hate & Lynne S. Taylor. (2020) Impact of Hypromellose Acetate Succinate Grade on Drug Amorphous Solubility and In Vitro Membrane Transport. Journal of Pharmaceutical Sciences 109:8, pages 2464-2473.
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Dongmei Li, Xiaodong She & Richard Calderone. (2020) The antifungal pipeline: the need is established. Are there new compounds?. FEMS Yeast Research 20:4.
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Bart Hens, Makoto Kataoka, Keisuke Ueda, Ping Gao, Yasuhiro Tsume, Patrick Augustijns, Kohsaku Kawakami & Shinji Yamashita. (2020) Biopredictive in vitro testing methods to assess intestinal drug absorption from supersaturating dosage forms. Journal of Drug Delivery Science and Technology 56, pages 101275.
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Hitomi Okada, Keisuke Ueda, Yuki Yasuda, Kenjirou Higashi, Motoki Inoue, Masataka Ito, Shuji Noguchi, Kohsaku Kawakami & Kunikazu Moribe. (2020) Correlation between drug dissolution and resistance to water-induced phase separation in solid dispersion formulations revealed by solid-state NMR spectroscopy. International Journal of Pharmaceutics 577, pages 119086.
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Maciej Nowak, Maciej Gajda, Przemysław Baranowski, Patrycja Szymczyk, Bożena Karolewicz & Karol P. Nartowski. (2019) Stabilisation and Growth of Metastable Form II of Fluconazole in Amorphous Solid Dispersions. Pharmaceutics 12:1, pages 12.
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Victoria Bustos-Terrones, Iris N. Serratos, Rubicelia Vargas, Bruno C. Landeros-Rivera, Yaneth A. Bustos-Terrones, Ana M. Soto Estrada, Jonathan O. Vicente Escobar, Mario A. Romero Romo, Jorge Uruchurtu, Carmina Menchaca, Juan M. Esparza Schulz & Armando Domínguez. (2018) SBA15-Fluconazole as a Protective Approach Against Mild Steel Corrosion: Synthesis, Characterization, and Computational Studies. ChemistryOpen 7:12, pages 984-994.
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Keisuke Ueda, Chisato Yamazoe, Yuki Yasuda, Kenjirou Higashi, Kohsaku Kawakami & Kunikazu Moribe. (2018) Mechanism of Enhanced Nifedipine Dissolution by Polymer-Blended Solid Dispersion through Molecular-Level Characterization. Molecular Pharmaceutics 15:9, pages 4099-4109.
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Keisuke Ueda, Harunobu Kanaya, Kenjirou Higashi, Keiji Yamamoto & Kunikazu Moribe. (2018) Molecular-level elucidation of saccharin-assisted rapid dissolution and high supersaturation level of drug from Eudragit ® E solid dispersion. International Journal of Pharmaceutics 538:1-2, pages 57-64.
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Rawan A. Fitaihi, Fadilah S. Aleanizy, Samar Elsamaligy, Hanaa A. Mahmoud & Mohsen A. Bayomi. (2018) Role of chitosan on controlling the characteristics and antifungal activity of bioadhesive fluconazole vaginal tablets. Saudi Pharmaceutical Journal 26:2, pages 151-161.
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Naoko Ohyagi, Keisuke Ueda, Kenjirou Higashi, Keiji Yamamoto, Kohsaku Kawakami & Kunikazu Moribe. (2017) Synergetic Role of Hypromellose and Methacrylic Acid Copolymer in the Dissolution Improvement of Amorphous Solid Dispersions. Journal of Pharmaceutical Sciences 106:4, pages 1042-1050.
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Abhishek Singh & Guy Van den Mooter. (2016) Spray drying formulation of amorphous solid dispersions. Advanced Drug Delivery Reviews 100, pages 27-50.
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Hye Jin Kim, Dae Hwan Shin, Eun Ah Lim & Jin-Seok Kim. (2014) Sustained-release formulation of sarpogrelate hydrochloride. Archives of Pharmacal Research 38:1, pages 35-41.
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Amitha Thakur, Dinesh Kumar, Rajesh Thipparaboina & Nalini R Shastri. (2014) Exploration of crystal simulation potential by fluconazole isomorphism and its application in improvement of pharmaceutical properties. Journal of Crystal Growth 406, pages 18-25.
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Ziyi Yang, Kathrin Nollenberger, Jessica Albers, Duncan Craig & Sheng Qi. (2013) Microstructure of an Immiscible Polymer Blend and Its Stabilization Effect on Amorphous Solid Dispersions. Molecular Pharmaceutics 10:7, pages 2767-2780.
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Stavroula G. Nanaki, Ioannis A. Koutsidis, Ioanna Koutri, Evangelos Karavas & Dimitrios Bikiaris. (2012) Miscibility study of chitosan/2-hydroxyethyl starch blends and evaluation of their effectiveness as drug sustained release hydrogels. Carbohydrate Polymers 87:2, pages 1286-1294.
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Hye Jin Kim, Su Hyun Lee, Eun Ah Lim & Jin-Seok Kim. (2011) Formulation optimization of solid dispersion of mosapride hydrochloride. Archives of Pharmacal Research 34:9, pages 1467-1475.
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Jože Kastelic, Žiga Hodnik, Primož Šket, Janez Plavec, Nina Lah, Ivan Leban, Matjaž Pajk, Odon Planinšek & Danijel Kikelj. (2010) Fluconazole Cocrystals with Dicarboxylic Acids. Crystal Growth & Design 10:11, pages 4943-4953.
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Konstantinos P. Koutroumanis, Konstantinos Avgoustakis & Dimitrios Bikiaris. (2010) Synthesis of cross-linked N-(2-carboxybenzyl)chitosan pH sensitive polyelectrolyte and its use for drug controlled delivery. Carbohydrate Polymers 82:1, pages 181-188.
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Santosh Kumar, Nidhi Nigam, T. Ghosh, Pradip K. Dutta, S.P. Singh, Prashant K. Datta, Lijia An & Tong Fei Shi. (2010) Preparation, characterization and optical properties of a novel azo-based chitosan biopolymer. Materials Chemistry and Physics 120:2-3, pages 361-370.
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