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ORIGINAL ARTICLE

Summary of evidence pointing to a role of the dorsal cochlear nucleus in the etiology of tinnitus

, PhD
Pages 20-26 | Published online: 08 Jul 2009

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Siobhan McGinnity, Elizabeth Francis Beach, Robert S. C. Cowan & Johannes Mulder. (2021) The hearing health of live-music sound engineers. Archives of Environmental & Occupational Health 76:6, pages 301-312.
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C.P. Lanting, E. De Kleine, H. Bartels & P. Van Dijk. (2008) Functional imaging of unilateral tinnitus using fMRI. Acta Oto-Laryngologica 128:4, pages 415-421.
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Articles from other publishers (59)

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Ji Hyung Lim, Jae Sang Han, Heesun Ahn, Yeonji Kim, Jae-Hyun Seo, So Young Park & Shi Nae Park. (2023) Therapeutic Response of Tinnitus Retraining in Patients With Tinnitus and Hearing Loss: A Short-Term Comparisonal Study on the Effect of Hearing Aid. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 66:5, pages 308-314.
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Thawann Malfatti, Barbara Ciralli, Markus M. Hilscher, Richardson N. Leao & Katarina E. Leao. (2022) Decreasing dorsal cochlear nucleus activity ameliorates noise-induced tinnitus perception in mice. BMC Biology 20:1.
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Shikha Spencer, Marzena Mielczarek, Jurek Olszewski, Magdalena Sereda, Iris Joossen, Hanne Vermeersch, Annick Gilles & Sarah Michiels. (2022) Effectiveness of bimodal auditory and electrical stimulation in patients with tinnitus: A feasibility study. Frontiers in Neuroscience 16.
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Stephen McInturff, Florent-Valéry Coen, Ariel E. Hight, Osama Tarabichi, Vivek V. Kanumuri, Nicolas Vachicouras, Stéphanie P. Lacour, Daniel J. Lee & M. Christian Brown. (2022) Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI). Journal of the Association for Research in Otolaryngology 23:3, pages 391-412.
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Hyun Lee, Dae Kang, Seung Yeo & Sang Kim. (2022) Hearing Aid Effects and Satisfaction in Patients with Tinnitus. Journal of Clinical Medicine 11:4, pages 1096.
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Timothy S. Balmer & Laurence O. Trussell. (2021) Trigeminal Contributions to the Dorsal Cochlear Nucleus in Mouse. Frontiers in Neuroscience 15.
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Meredith E. Adams, Tina C. Huang, Srikantan Nagarajan & Steven W. Cheung. (2020) Tinnitus Neuroimaging. Otolaryngologic Clinics of North America 53:4, pages 583-603.
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Minke J C van den Berge, Marc J M C van Dijk, Jan D M Metzemaekers, Bert Maat, Rolien H Free & Pim van Dijk. (2019) An auditory brainstem implant for treatment of unilateral tinnitus: protocol for an interventional pilot study. BMJ Open 9:6, pages e026185.
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Gusta van Zwieten, Ali Jahanshahi, Marlieke L. van Erp, Yasin Temel, Robert J. Stokroos, Marcus L. F. Janssen & Jasper V. Smit. (2019) Alleviation of Tinnitus With High-Frequency Stimulation of the Dorsal Cochlear Nucleus: A Rodent Study. Trends in Hearing 23, pages 233121651983508.
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Zeina Chemali, R. Nehmé & Gregory Fricchione. 2019. Psychopharmacology of Neurologic Disease. Psychopharmacology of Neurologic Disease 365 381 .
Haúla Faruk Haider, Tijana Bojić, Sara F. Ribeiro, João Paço, Deborah A. Hall & Agnieszka J. Szczepek. (2018) Pathophysiology of Subjective Tinnitus: Triggers and Maintenance. Frontiers in Neuroscience 12.
Crossref
Lawrence R. Lustig. (2018) Diseases and targets for local drug delivery to the inner ear. Hearing Research 368, pages 3-9.
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Thomas Brozoski, Daniel Brozoski, Kurt Wisner & Carol Bauer. (2017) Chronic tinnitus and unipolar brush cell alterations in the cerebellum and dorsal cochlear nucleus. Hearing Research 350, pages 139-151.
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Haúla F. Haider, Derek J. Hoare, Raquel F. P. Costa, Iskra Potgieter, Dimitris Kikidis, Alec Lapira, Christos Nikitas, Helena Caria, Nuno T. Cunha & João C. Paço. (2017) Pathophysiology, Diagnosis and Treatment of Somatosensory Tinnitus: A Scoping Review. Frontiers in Neuroscience 11.
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Marie Wegger, Therese Ovesen & Dalia Gustaityte Larsen. (2017) Acoustic Coordinated Reset Neuromodulation: A Systematic Review of a Novel Therapy for Tinnitus. Frontiers in Neurology 8.
Crossref
Susan E. Shore, Larry E. Roberts & Berthold Langguth. (2016) Maladaptive plasticity in tinnitus — triggers, mechanisms and treatment. Nature Reviews Neurology 12:3, pages 150-160.
Crossref
G.-D. Chen, A. Sheppard & R. Salvi. (2016) Noise trauma induced plastic changes in brain regions outside the classical auditory pathway. Neuroscience 315, pages 228-245.
Crossref
Dirk De Ridder, Sven Vanneste, Berthold Langguth & Rodolfo Llinas. (2015) Thalamocortical Dysrhythmia: A Theoretical Update in Tinnitus. Frontiers in Neurology 6.
Crossref
J.V. Smit, M.L.F. Janssen, H. Schulze, A. Jahanshahi, J.J. Van Overbeeke, Y. Temel & R.J. Stokroos. (2015) Deep brain stimulation in tinnitus: Current and future perspectives. Brain Research 1608, pages 51-65.
Crossref
Konstantin V. Slavin, Alexios G. Carayannopoulos, Mark Plazier, Sven Vanneste & Dirk De Ridder. 2015. Textbook of Neuromodulation. Textbook of Neuromodulation 19 33 .
Tessa-Jonne F. Ropp, Kerrie L. Tiedemann, Eric D. Young & Bradford J. May. (2014) Effects of Unilateral Acoustic Trauma on Tinnitus-Related Spontaneous Activity in the Inferior Colliculus. Journal of the Association for Research in Otolaryngology 15:6, pages 1007-1022.
Crossref
Mia T Minen, Joan Camprodon, Romy Nehme & Zeina Chemali. (2014) The neuropsychiatry of tinnitus: a circuit-based approach to the causes and treatments available. Journal of Neurology, Neurosurgery & Psychiatry 85:10, pages 1138-1144.
Crossref
Joan S. Baizer, Keit Men Wong, Nicholas A. Paolone, Nadav Weinstock, Richard J. Salvi, Senthilvelan Manohar, Sandra F. Witelson, James F. Baker, Chet C. Sherwood & Patrick R. Hof. (2014) Laminar and Neurochemical Organization of the Dorsal Cochlear Nucleus of the Human, Monkey, Cat, and Rodents. The Anatomical Record 297:10, pages 1865-1884.
Crossref
Valdete Alves Valentins dos Santos-Filha, Alessandra Giannella Samelli & Carla Gentile Matas. (2014) Noise-induced tinnitus: auditory evoked potential in symptomatic and asymptomatic patients. Clinics 69:7, pages 487-490.
Crossref
Dirk De Ridder, Sven Vanneste, Nathan Weisz, Alain Londero, Winnie Schlee, Ana Belen Elgoyhen & Berthold Langguth. (2014) An integrative model of auditory phantom perception: Tinnitus as a unified percept of interacting separable subnetworks. Neuroscience & Biobehavioral Reviews 44, pages 16-32.
Crossref
Anthony T. Cacace, Tom Brozoski, Bruce Berkowitz, Carol Bauer, Boris Odintsov, Magnus Bergkvist, James Castracane, Jinsheng Zhang & Avril Genene Holt. (2014) Manganese enhanced magnetic resonance imaging (MEMRI): A powerful new imaging method to study tinnitus. Hearing Research 311, pages 49-62.
Crossref
N. Paolone, S. Manohar, S.H. Hayes, K.M. Wong, R.J. Salvi & J.S. Baizer. (2014) Dissociation of doublecortin expression and neurogenesis in unipolar brush cells in the vestibulocerebellum and dorsal cochlear nucleus of the adult rat. Neuroscience 265, pages 323-331.
Crossref
Thomas J. Brozoski & Carol A. Bauer. 2014. Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics. Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics 261 275 .
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Nadia Müller, Isabel Lorenz, Berthold Langguth & Nathan Weisz. (2013) rTMS Induced Tinnitus Relief Is Related to an Increase in Auditory Cortical Alpha Activity. PLoS ONE 8:2, pages e55557.
Crossref
Andre M. Wineland, Harold Burton & Jay Piccirillo. (2012) Functional Connectivity Networks in Nonbothersome Tinnitus. Otolaryngology–Head and Neck Surgery 147:5, pages 900-906.
Crossref
Joan S. Baizer, Senthilvelan Manohar, Nicholas A. Paolone, Nadav Weinstock & Richard J. Salvi. (2012) Understanding tinnitus: The dorsal cochlear nucleus, organization and plasticity. Brain Research 1485, pages 40-53.
Crossref
Guang-Di Chen, Senthilvelan Manohar & Richard Salvi. (2012) Amygdala hyperactivity and tonotopic shift after salicylate exposure. Brain Research 1485, pages 63-76.
Crossref
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Crossref
Paul S. Larson & Steven W. Cheung. (2012) Deep Brain Stimulation in Area LC Controllably Triggers Auditory Phantom Percepts. Neurosurgery 70:2, pages 398-406.
Crossref
Xiaoping Du, Kejian Chen, Chul-Hee Choi, Wei Li, Weihua Cheng, Charles Stewart, Ning Hu, Robert A. Floyd & Richard D. Kopke. (2012) Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment. Hearing Research 283:1-2, pages 1-13.
Crossref
Calvin Wu, Kamakshi Gopal, Guenter W. Gross, Thomas J. Lukas & Ernest J. Moore. (2011) An in vitro model for testing drugs to treat tinnitus. European Journal of Pharmacology 667:1-3, pages 188-194.
Crossref
Larry E. Roberts, Jos J. Eggermont, Donald M. Caspary, Susan E. Shore, Jennifer R. Melcher & James A. Kaltenbach. (2010) Ringing Ears: The Neuroscience of Tinnitus: Figure 1.. The Journal of Neuroscience 30:45, pages 14972-14979.
Crossref
S.W. Cheung & P.S. Larson. (2010) Tinnitus modulation by deep brain stimulation in locus of caudate neurons (area LC). Neuroscience 169:4, pages 1768-1778.
Crossref
Marlies Knipper, Ulrike Zimmermann & Marcus Müller. (2010) Molecular aspects of tinnitus. Hearing Research 266:1-2, pages 60-69.
Crossref
Christina L. Runge-Samuelson & David R. Friedland. 2010. Cummings Otolaryngology - Head and Neck Surgery. Cummings Otolaryngology - Head and Neck Surgery 1831 1837 .
Jaime G. Mancilla & Paul B. Manis. (2009) Two Distinct Types of Inhibition Mediated by Cartwheel Cells in the Dorsal Cochlear Nucleus. Journal of Neurophysiology 102:2, pages 1287-1295.
Crossref
G. Moffat, K. Adjout, S. Gallego, H. Thai-Van, L. Collet & A.J. Noreña. (2009) Effects of hearing aid fitting on the perceptual characteristics of tinnitus. Hearing Research 254:1-2, pages 82-91.
Crossref
Jeremy G. Turner & Jennifer Parrish. (2008) Gap Detection Methods for Assessing Salicylate-Induced Tinnitus and Hyperacusis in Rats. American Journal of Audiology 17:2.
Crossref
James A. Kaltenbach & Donald A. Godfrey. (2008) Dorsal Cochlear Nucleus Hyperactivity and Tinnitus: Are They Related?. American Journal of Audiology 17:2.
Crossref
Thanos Tzounopoulos. (2008) Mechanisms of Synaptic Plasticity in the Dorsal Cochlear Nucleus: Plasticity-Induced Changes That Could Underlie Tinnitus. American Journal of Audiology 17:2.
Crossref
E. Biesinger, A. Reißhauer & B. Mazurek. (2008) Die Rolle der Halswirbelsäule und des Kiefergelenks bei TinnitusThe role of the cervical spine and the craniomandibular system in the pathogenesis of tinnitus. HNO 56:7, pages 673-677.
Crossref
Devon E. HintonSusan D. Hinton, Reattidara J.-R. Loeum, Vuth Pich & Mark H. Pollack. (2008) The `Multiplex Model' of Somatic Symptoms: Application to Tinnitus among Traumatized Cambodian Refugees. Transcultural Psychiatry 45:2, pages 287-317.
Crossref
R. Dauman & M. Laffargue. (2008) Acúfenos subjetivos: modelos fisiopatológicos e investigación clínica. EMC - Otorrinolaringología 37:1, pages 1-11.
Crossref
R. Dauman & M. Laffargue. (2007) Acouphènes subjectifs : modèles physiopathologiques et recherche clinique. EMC - Oto-rhino-laryngologie 2:4, pages 1-10.
Crossref
P.J. Jastreboff. 2007. Tinnitus: Pathophysiology and Treatment. Tinnitus: Pathophysiology and Treatment 415 423 .
L. Del Bo & U. Ambrosetti. 2007. Tinnitus: Pathophysiology and Treatment. Tinnitus: Pathophysiology and Treatment 341 345 .
James A. Kaltenbach. 2007. Tinnitus: Pathophysiology and Treatment. Tinnitus: Pathophysiology and Treatment 89 106 .
Nathan Weisz, Katalin Dohrmann & Thomas Elbert. 2007. Tinnitus: Pathophysiology and Treatment. Tinnitus: Pathophysiology and Treatment 61 70 .

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