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Cancer Investigation Volume 23, 2005 - Issue 6
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Original Article

Eradication of Minimal Residual Disease with Alemtuzumab in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients: The Need for a Standard Method of Detection and the Potential Impact of Bone Marrow Clearance on Disease Outcome

Marco Montillo Department of Oncology-Haematology, Niguarda Ca'Granda Hospital, Milan, ItalyCorrespondence[email protected]
,
Timo Schinkoethe First Department of Internal Medicine, University of Cologne, Cologne, Germany
&
Thomas Elter First Department of Internal Medicine, University of Cologne, Cologne, Germany
Pages 488-496 | Published online: 11 Jun 2009

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Carmen Diana Schweighofer & Clemens-Martin Wendtner. (2010) First-line treatment of chronic lymphocytic leukemia: role of alemtuzumab. OncoTargets and Therapy 3, pages 53-67.
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Tadeusz Robak. (2008) Alemtuzumab for B-cell chronic lymphocytic leukemia. Expert Review of Anticancer Therapy 8:7, pages 1033-1051.
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Mohamed A Kharfan-Dabaja, Rabih Fahed, Mohamad Hussein & Edgardo S Santos. (2007) Evolving role of monoclonal antibodies in the treatment of chronic lymphocytic leukemia. Expert Opinion on Investigational Drugs 16:11, pages 1799-1815.
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Farhad Ravandi & Susan O'Brien. (2006) Alemtuzumab in CLL and Other Lymphoid Neoplasms. Cancer Investigation 24:7, pages 718-725.
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Cordelia Sever, Charles L. Abbott, Monica E. de Baca, Joseph D. Khoury, Sherrie L. Perkins, Kaaren Kemp Reichard, Ann Taylor, Howard R. Terebelo, Carol Colasacco, R. Bryan Rumble & Nicole E. Thomas. (2016) Bone Marrow Synoptic Reporting for Hematologic Neoplasms: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center. Archives of Pathology & Laboratory Medicine 140:9, pages 932-949.
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Shuang Bai, Rong Deng, Hong Xiang, Manish Gupta, Luna Musib, Banmeet Anand & Bert Lum. 2014. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics 585 624 .
M. M. Sartor & D. J. Gottlieb. (2013) A single tube 10‐color flow cytometry assay optimizes detection of minimal residual disease in chronic lymphocytic leukemia. Cytometry Part B: Clinical Cytometry 84B:2, pages 96-103.
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Femke Van Bockstaele, Bruno Verhasselt & Jan Philippé. (2009) Prognostic markers in chronic lymphocytic leukemia: A comprehensive review. Blood Reviews 23:1, pages 25-47.
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C.E. Pedreira, E.S. Costa, J. Almeida, C. Fernandez, S. Quijano, J. Flores, S. Barrena, Q. Lecrevisse, J.J.M. Van Dongen & A. Orfao. (2008) A probabilistic approach for the evaluation of minimal residual disease by multiparameter flow cytometry in leukemic B-cell chronic lymphoproliferative disorders. Cytometry Part A 73A:12, pages 1141-1150.
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Carlos E. Pedreira, Elaine S. Costa, Susana Barrena, Quentin Lecrevisse, Julia Almeida, Jacques J. M. van Dongen & Alberto Orfao. (2008) Generation of flow cytometry data files with a potentially infinite number of dimensions. Cytometry Part A 73A:9, pages 834-846.
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Sandra Quijano, Antonio López, Ana Rasillo, José María Sayagués, Susana Barrena, Maria Luz Sánchez, Cristina Teodosio, Pilar Giraldo, Manuel Giralt, M. Carmen Pérez, Mercedes Romero, Luis Perdiguer & Alberto Orfao. (2007) Impact of trisomy 12, del(13q), del(17p), and del(11q) on the immunophenotype, DNA ploidy status, and proliferative rate of leukemic B‐cells in chronic lymphocytic leukemia. Cytometry Part B: Clinical Cytometry 74B:3, pages 139-149.
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Michael R. Grever, Leslie A. Andritsos & Gerard Lozanski. 2008. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 2293 2308 .
Dong Hwan Kim. 2009. Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response. Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response 203 229 .
Peter Hillmen, Aleksander B. Skotnicki, Tadeusz Robak, Branimir Jaksic, Anna Dmoszynska, Jingyang Wu, Cynthia Sirard & Jiri Mayer. (2007) Alemtuzumab Compared With Chlorambucil As First-Line Therapy for Chronic Lymphocytic Leukemia. Journal of Clinical Oncology 25:35, pages 5616-5623.
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M. Montagna, M.A. Avanzini, L. Visai, F. Locatelli, M. Montillo, E. Morra & M.B. Regazzi. (2016) A New Sensitive Enzyme-Linked Immunosorbent Assay (ELISA) for Alemtuzumab Determination: Development, Validation and Application. International Journal of Immunopathology and Pharmacology 20:2, pages 363-371.
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Mohamed A. Kharfan-Dabaja, Claudio Anasetti & Edgardo S. Santos. (2007) Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia: An Evolving Concept. Biology of Blood and Marrow Transplantation 13:4, pages 373-385.
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François LassaillyMarie-Joëlle MozziconacciTetsuro NoguchiDidier BechlianJosé AdelaideFrédéric FinaPierre-Marie MartinHagay SobolLuc XerriDaniel BirnbaumChristian Chabannon. (2007) Comparison of a Selection of Rapid Automated DNA and RNA Extraction Technologies for Detection of Somatic or Constitutional Gene Abnormalities in Cancer Diagnosis. Cell Preservation Technology 5:1, pages 2-15.
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. (2006) Current Awareness in Hematological Oncology. Hematological Oncology 24:1, pages 38-45.
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