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Cancer Investigation Volume 24, 2006 - Issue 7
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ORIGINAL ARTICLE

A Pilot Phase II Trial of Valspodar Modulation of Multidrug Resistance to Paclitaxel in the Treatment of Metastatic Carcinoma of the Breast (E1195): A Trial of the Eastern Cooperative Oncology Group

Robert W. Carlson Stanford University, Stanford, California, USA
, M.D.,
Anne M. O'Neill Dana Farber Cancer Institute, Boston, Massachusetts, USA
, M.S.,
Lori J. Goldstein Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
, M.D.,
Branimir I. Sikic Stanford University, Stanford, California, USA
, M.D.,
Neil Abramson Baptist Cancer Institute, Jacksonville, Florida, USA
, M.D.,
James A. Stewart University of Wisconsin, Madison, Wisconsin, USA
, M.D.,
Nancy E. Davidson Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA
, M.D. &
William C. Wood Emory University, Atlanta, Georgia, USA
, M.D. show all
Pages 677-681 | Published online: 11 Jun 2009

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Agata M. Gawel, Marlena Godlewska, Marta Grech-Baran, Anna Stachurska & Damian Gawel. (2019) MIX2: A Novel Natural Multi-Component Modulator of Multidrug-Resistance and Hallmarks of Cancer Cells. Nutrition and Cancer 71:2, pages 334-347.
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Iben Kümler, Jan Stenvang, José Moreira, Nils Brünner & Dorte Lisbet Nielsen. (2015) Drug transporters in breast cancer: response to anthracyclines and taxanes. Expert Review of Anticancer Therapy 15:9, pages 1075-1092.
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Can Atalay. (2007) Multi-drug resistance and cancer. Expert Opinion on Therapeutic Patents 17:5, pages 511-520.
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Yueh-Te Lin, Joseph Lin, Yi-En Liu, Yun-Cen Chen, Shiang-Ting Liu, Kai-Wen Hsu, Dar-Ren Chen & Han-Tsang Wu. (2022) USP7 Induces Chemoresistance in Triple-Negative Breast Cancer via Deubiquitination and Stabilization of ABCB1. Cells 11:20, pages 3294.
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Sven Marcel Stefan & Michael Wiese. (2019) Small-molecule inhibitors of multidrug resistance-associated protein 1 and related processes: A historic approach and recent advances. Medicinal Research Reviews 39:1, pages 176-264.
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Renata Silva, Vânia Vilas-Boas, Helena Carmo, Ricardo Jorge Dinis-Oliveira, Félix Carvalho, Maria de Lourdes Bastos & Fernando Remião. (2015) Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy. Pharmacology & Therapeutics 149, pages 1-123.
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Michelle McCarthy, Gregory Auda, Suchi Agrawal, Amy Taylor, Zack Backstrom, Debasis Mondal, Krzysztof Moroz & Srikanta Dash. (2014) In vivo anticancer synergy mechanism of doxorubicin and verapamil combination treatment is impaired in BALB/c mice with metastatic breast cancer. Experimental and Molecular Pathology 97:1, pages 6-15.
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Amita Kapoor, Majid Iqbal, Sophie Petropoulos, Hay Lam Ho, William Gibb & Stephen G. Matthews. (2013) Effects of Sertraline and Fluoxetine on P-Glycoprotein at Barrier Sites: In Vivo and In Vitro Approaches. PLoS ONE 8:2, pages e56525.
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Makrem Ben Reguiga, Celine Bouquet, Robert Farinotti & Laurence Bonhomme-Faivre. (2012) Interferon-alpha improves docetaxel antitumoral and antimetastatic efficiency in Lewis lung carcinoma bearing mice. Life Sciences 91:17-18, pages 843-851.
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Laleh Amiri-Kordestani, Agnes Basseville, Karen Kurdziel, Antonio Tito Fojo & Susan E. Bates. (2012) Targeting MDR in breast and lung cancer: Discriminating its potential importance from the failure of drug resistance reversal studies. Drug Resistance Updates 15:1-2, pages 50-61.
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Till Krech, Elisa Scheuerer, Robert Geffers, Hans Kreipe, Ulrich Lehmann & Matthias Christgen. (2012) ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells. Cancer Letters 315:2, pages 153-160.
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Sagar Agarwal, Ramola Sane, Rajneet Oberoi, John R. Ohlfest & William F. Elmquist. (2011) Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain. Expert Reviews in Molecular Medicine 13.
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Lyndal J. Tacon, Ruth S. PrichardPatsy S. H. Soon, Bruce G. Robinson, Roderick J. Clifton-Bligh & Stan B. Sidhu. (2011) Current and Emerging Therapies for Advanced Adrenocortical Carcinoma. The Oncologist 16:1, pages 36-48.
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Rudel A. Saunders, Kazuyuki Fujii, Leah Alabanza, Roald Ravatn, Tsunekazu Kita, Kazuya Kudoh, Masahiro Oka & Khew-Voon Chin. (2010) Altered phospholipid transfer protein gene expression and serum lipid profile by topotecan. Biochemical Pharmacology 80:3, pages 362-369.
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Nicola Antonio Colabufo, Francesco Berardi, Mariangela Cantore, Marialessandra Contino, Carmela Inglese, Mauro Niso & Roberto Perrone. (2009) Perspectives of P-Glycoprotein Modulating Agents in Oncology and Neurodegenerative Diseases: Pharmaceutical, Biological, and Diagnostic Potentials. Journal of Medicinal Chemistry 53:5, pages 1883-1897.
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Philippe L. Bedard, Angelo Di Leo & Martine J. Piccart-Gebhart. (2009) Taxanes: optimizing adjuvant chemotherapy for early-stage breast cancer. Nature Reviews Clinical Oncology 7:1, pages 22-36.
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Krupa J Patel & Ian F Tannock. (2009) The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors. BMC Cancer 9:1.
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Fei Shen, Barbara J. Bailey, Shaoyou Chu, Aimee K. Bence, Xinjian Xue, Priscilla Erickson, Ahmad R. Safa, William T. Beck & Leonard C. Erickson. (2009) Dynamic Assessment of Mitoxantrone Resistance and Modulation of Multidrug Resistance by Valspodar (PSC833) in Multidrug Resistance Human Cancer Cells. Journal of Pharmacology and Experimental Therapeutics 330:2, pages 423-429.
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Tatiana Bogush & Jacques Robert. 2009. ABC Transporters and Multidrug Resistance. ABC Transporters and Multidrug Resistance 349 362 .
Can Atalay. 2008. Methods of Cancer Diagnosis, Therapy and Prognosis. Methods of Cancer Diagnosis, Therapy and Prognosis 637 652 .
Serena Marchetti, Roberto Mazzanti, Jos H. Beijnen & Jan H. M. Schellens. (2007) Concise Review: Clinical Relevance of Drug–Drug and Herb–Drug Interactions Mediated by the ABC Transporter ABCB1 (MDR1, P-glycoprotein). The Oncologist 12:8, pages 927-941.
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