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Cancer Investigation Volume 26, 2008 - Issue 7
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ORIGINAL ARTICLESCellular and Molecular Biology

Herbal Isoprenols Induce Apoptosis in Human Colon Cancer Cells Through Transcriptional Activation of PPARγ

Kathy Ka-Wai Au-Yeung Pharmacology and Toxicology Laboratory, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
,
Po-Ling Liu Pharmacology and Toxicology Laboratory, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
,
Cecilia Chan Pharmacology and Toxicology Laboratory, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
,
Wing-Yee Wu Pharmacology and Toxicology Laboratory, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
,
Susanna Sau-Tuen Lee Department of Biochemistry, the Chinese University of Hong Kong, Hong Kong, China
&
Joshua Ka-Shun Ko Pharmacology and Toxicology Laboratory, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
Pages 708-717 | Published online: 11 Jun 2009

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Gyllyandeson De Araújo Delmondes, Izabel Cristina Santiago Lemos, Diógenes De Queiroz Dias, Glacithane Lins Da Cunha, Isaac Moura Araújo, Roseli Barbosa, Henrique Douglas Melo Coutinho, Cícero Francisco Bezerra Felipe, José Maria Barbosa-Filho, Natanael Teles Ramos De Lima, Irwin Rose Alencar De Menezes & Marta Regina Kerntopf. (2020) Pharmacological applications of farnesol (C15H26O): a patent review. Expert Opinion on Therapeutic Patents 30:3, pages 227-234.
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Bokyung Sung, Sahdeo Prasad, Vivek R. Yadav, Afsaneh Lavasanifar & Bharat B. Aggarwal. (2011) Cancer and diet: How are they related?. Free Radical Research 45:8, pages 864-879.
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Articles from other publishers (17)

Mohammad Ali, Shahid Ud Din Wani, Md Salahuddin, Manjula S.N.Mruthunjaya K, Tathagata Dey, Mohammed Iqbal Zargar & Jagadeesh Singh. (2023) Recent advance of herbal medicines in cancer- a molecular approach. Heliyon 9:2, pages e13684.
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Abozer Y. Elderdery, Badr Alzahrani, Siddiqa M. A. Hamza, Gomaa Mostafa-Hedeab, Pooi Ling Mok & Suresh Kumar Subbiah. (2022) Synthesis of Zinc Oxide (ZnO)-Titanium Dioxide (TiO2)-Chitosan-Farnesol Nanocomposites and Assessment of Their Anticancer Potential in Human Leukemic MOLT-4 Cell Line. Bioinorganic Chemistry and Applications 2022, pages 1-11.
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Sarabjit Kaur, Monika Sachdeva, Hasandeep Singh, Arshdeep Singh, Jaipal Kaur, Archana Rani, Saroj Arora & Balbir Singh. 2022. Herbal Bioactive-Based Drug Delivery Systems. Herbal Bioactive-Based Drug Delivery Systems 1 24 .
Liwei Wu, Chuanyong Guo & Jianye Wu. (2020) Therapeutic potential of PPARγ natural agonists in liver diseases. Journal of Cellular and Molecular Medicine 24:5, pages 2736-2748.
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Wolfgang Vivas, Ines Leonhardt, Kerstin Hünniger, Antje Häder, Alessandra Marolda & Oliver Kurzai. (2019) Multiple Signaling Pathways Involved in Human Dendritic Cell Maturation Are Affected by the Fungal Quorum-Sensing Molecule Farnesol. The Journal of Immunology 203:11, pages 2959-2969.
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Jong Hyun Lee, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Omar H.M. Shair, Gautam Sethi & Kwang Seok Ahn. (2019) Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway. Pharmacological Research 150, pages 104504.
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Gyllyandeson de Araújo Delmondes, Daniel Souza Bezerra, Diógenes de Queiroz Dias, Alex de Souza Borges, Isaac Moura Araújo, Glacithane Lins da Cunha, Paulo Felipe Ribeiro Bandeira, Roseli Barbosa, Henrique Douglas Melo Coutinho, Cícero Francisco Bezerra Felipe, José Maria Barbosa-Filho, Irwin Rose Alencar de Menezes & Marta Regina Kerntopf. (2019) Toxicological and pharmacologic effects of farnesol (C15H26O): A descriptive systematic review. Food and Chemical Toxicology 129, pages 169-200.
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Hye-Lin Kim, Yunu Jung, Jinbong Park, Dong-Hyun Youn, JongWook Kang, Seona Lim, Beom Su Lee, Mi-Young Jeong, Seong-Kyu Choe, Raekil Park, Kwang Seok Ahn & Jae-Young Um. (2017) Farnesol Has an Anti-obesity Effect in High-Fat Diet-Induced Obese Mice and Induces the Development of Beige Adipocytes in Human Adipose Tissue Derived-Mesenchymal Stem Cells. Frontiers in Pharmacology 8.
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Sheida Torabi & Huanbiao Mo. (2015) Trans, trans -farnesol as a mevalonate-derived inducer of murine 3T3-F442A pre-adipocyte differentiation . Experimental Biology and Medicine 241:5, pages 493-500.
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Rajasekaran Santhanasabapathy & Ganapasam Sudhandiran. (2015) Farnesol attenuates lipopolysaccharide-induced neurodegeneration in Swiss albino mice by regulating intrinsic apoptotic cascade. Brain Research 1620, pages 42-56.
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Jong Hyun Lee, Chulwon Kim, Sung-Hoon Kim, Gautam Sethi & Kwang Seok Ahn. (2015) Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway. Cancer Letters 360:2, pages 280-293.
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Shu-Yi Yin, Wen-Chi Wei, Feng-Yin Jian & Ning-Sun Yang. (2013) Therapeutic Applications of Herbal Medicines for Cancer Patients. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-15.
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María Gómez-Serranillos Cuadrado, María Ortega Hernández-Agero, Olga Palomino Ruiz-Poveda & María Carretero Accame. 2012. Medicinal Plants. Medicinal Plants 412 471 .
Rajasekhar Katuru, Nicolle V Fernandes, Manal Elfakhani, Dibyendu Dutta, Nathaniel Mills, DiAnna L Hynds, Clay King & Huanbiao Mo. (2011) Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. Experimental Biology and Medicine 236:5, pages 604-613.
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Matthew Milkevitch, Nancy J. Beardsley & E. James Delikatny. (2010) Phenylbutyrate induces apoptosis and lipid accumulations via a peroxisome proliferator-activated receptor gamma-dependent pathway. NMR in Biomedicine 23:5, pages 473-479.
Crossref
Kathy Ka-Wai Auyeung & Joshua Ka-Shun Ko. (2009) Novel herbal flavonoids promote apoptosis but differentially induce cell cycle arrest in human colon cancer cell. Investigational New Drugs 28:1, pages 1-13.
Crossref
Joung Hyuck Joo & Anton M. Jetten. (2010) Molecular mechanisms involved in farnesol-induced apoptosis. Cancer Letters 287:2, pages 123-135.
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