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Cancer Investigation Volume 26, 2008 - Issue 10
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ORIGINAL ARTICLESClinical Translational Therapeutics

PIK3CA Mutations and BRCA1 Expression in Breast Cancer: Potential Biomarkers for Chemoresistance

Mariacarmela Santarpia Human Pathology Department, Medical Oncology Unit, University of Messina, Italy; Medical Oncology Service, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain
,
Giuseppe Altavilla Human Pathology Department, Medical Oncology Unit, University of Messina, Italy
,
Mireia Margeli Medical Oncology Service, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain
,
Beatriz Cirauqui Medical Oncology Service, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain
,
Mario Mesiti Human Pathology Department, Medical Oncology Unit, University of Messina, Italy
,
Vittorio Cavallari Human Pathology Department, Medical Oncology Unit, University of Messina, Italy
,
Jose Luis Ramirez Medical Oncology Service, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain
,
Maria Sanchez-Ronco Health Science and Social Medicine Department, Preventive Medicine and Public Health Unit, University of Alcala de Henares, Alcala de Henares, Spain
,
Libero Santarpia Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA
,
Miquel Taron Medical Oncology Service, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain
&
Rafael Rosell Medical Oncology Service, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain
 show all
Pages 1044-1051 | Published online: 11 Jun 2009

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Niki Karachaliou, Maria de los Llanos Gil Moreno, Aaron E. Sosa, Mariacarmela Santarpia, Chiara Lazzari, Alejandra Rodriguez Capote, Bartomeu Massuti & Rafael Rosell. (2017) Using genetics to predict patient response to platinum-based chemotherapy. Expert Review of Precision Medicine and Drug Development 2:1, pages 21-32.
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Nikolaos Nikoleousakos, Panagiotis Dalezis, Aikaterini Polonifi, Elena G. Geromichalou, Sofia Sagredou, Constantinos E. Alifieris, Maria V. Deligiorgi, Vasiliki Sarli & Dimitrios T. Trafalis. (2021) Cytocidal Antitumor Effects against Human Ovarian Cancer Cells Induced by B-Lactam Steroid Alkylators with Targeted Activity against Poly (ADP-Ribose) Polymerase (PARP) Enzymes in a Cell-Free Assay. Biomedicines 9:8, pages 1028.
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Luca Campedel, Paul Blanc-Durand, Asker Bin Asker, Jacqueline Lehmann-Che, Caroline Cuvier, Cedric De Bazelaire, Luis Teixeira, Stephanie Becourt, Florence Ledoux, Hamid Hocini, Edwige Bourstyn, Catherine Miquel, Sophie Guillerm, Patrick Charveriat, Marc Espié, Anne De Roquancourt, Anne-Sophie Hamy & Sylvie Giacchetti. (2020) Prognostic Impact of Stromal Immune Infiltration before and after Neoadjuvant Chemotherapy (NAC) in Triple Negative Inflammatory Breast Cancers (TNIBC) Treated with Dose-Dense Dose-Intense NAC. Cancers 12:9, pages 2657.
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Vaishali Jayashankar & Aimee L. Edinger. (2020) Macropinocytosis confers resistance to therapies targeting cancer anabolism. Nature Communications 11:1.
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Claudia Gasch, Brendan Ffrench, John J. O’Leary & Michael F. Gallagher. (2017) Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention. Molecular Cancer 16:1.
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Brendan Ffrench, Claudia Gasch, Karsten Hokamp, Cathy Spillane, Gordon Blackshields, Thamir Mahmoud Mahgoub, Mark Bates, Louise Kehoe, Aoibhinn Mooney, Ronan Doyle, Brendan Doyle, Dearbhaile O'Donnell, Noreen Gleeson, Bryan T Hennessy, Britta Stordal, Ciaran O'Riain, Helen Lambkin, Sharon O'Toole, John J O'Leary & Michael F Gallagher. (2017) CD10−/ALDH− cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy. Cell Death & Disease 8:10, pages e3128-e3128.
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Bo Pang, Shi Cheng, Shi-Peng Sun, Cheng An, Zhi-Yuan Liu, Xue Feng & Gui-Jian Liu. (2014) Prognostic role of PIK3CA mutations and their association with hormone receptor expression in breast cancer: a meta-analysis. Scientific Reports 4:1.
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Jacqueline Lehmann-Che, Anne-Sophie Hamy, Raphaël Porcher, Marc Barritault, Fatiha Bouhidel, Hanadi Habuellelah, Solenne Leman-Detours, Anne de Roquancourt, Laurence Cahen-Doidy, Edwige Bourstyn, Patricia de Cremoux, Cedric de Bazelaire, Marcela Albiter, Sylvie Giacchetti, Caroline Cuvier, Anne Janin, Marc Espié, Hugues de Thé & Philippe Bertheau. (2013) Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15. Breast Cancer Research 15:3.
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C.B. Murat, P.B.S. Braga, M.A.H.Z. Fortes, M.D. Bronstein, M.L.C. Corrêa-Giannella & R.R. Giorgi. (2012) Mutation and genomic amplification of the PIK3CA proto-oncogene in pituitary adenomas. Brazilian Journal of Medical and Biological Research 45:9, pages 851-855.
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