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Cancer Investigation Volume 27, 2009 - Issue 2
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ORIGINAL ARTICLES Clinical Translational Therapeutics

Capecitabine, Oxaliplatin and Radiotherapy: A Phase IB Neoadjuvant Study for Esophageal Cancer with Gene Expression Analysis

Milind M. Javle Department of Gastrointestinal Medical Oncology, UT-MD Anderson Cancer Institute, Houston, Texas, USA; Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Gary Yang Department Radiation, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Chumy E. Nwogu Department of Surgery, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Gregory E. Wilding Department of Biostatistics, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Linda O'Malley Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Sanjay Vinjamaram Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Michael D. Schiff Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Hector R. Nava Department of Surgery, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Charles LeVea Department of Pathology, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Kimberly R. Clark Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Joshua D. Prey Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
,
Patrick F. Smith Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA; Roche Pharmaceuticals, Nutley, New Jersey, USA
&
Lakshmi Pendyala Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
 show all
Pages 193-200 | Published online: 11 Jun 2009

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Gianluca Tomasello, Michele Ghidini, Sandro Barni, Rodolfo Passalacqua & Fausto Petrelli. (2017) Overview of different available chemotherapy regimens combined with radiotherapy for the neoadjuvant and definitive treatment of esophageal cancer. Expert Review of Clinical Pharmacology 10:6, pages 649-660.
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Elizabeta C Popa & Manish A Shah. (2013) Capecitabine in the treatment of esophageal and gastric cancers. Expert Opinion on Investigational Drugs 22:12, pages 1645-1657.
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Jen-Hao Yeh, Yung-Sung Yeh, Hsiang-Lin Tsai, Ching-Wen Huang, Tsung-Kun Chang, Wei-Chih Su & Jaw-Yuan Wang. (2022) Neoadjuvant Chemoradiotherapy for Locally Advanced Gastric Cancer: Where Are We at?. Cancers 14:12, pages 3026.
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Usha Malhotra, Sarbajit Mukherjee, Christos Fountzilas, Patrick Boland, Austin Miller, Santosh Patnaik, Kristopher Attwood, Sai Yendamuri, Araba Adjei, Eric Kannisto, Mateusz Opyrchal, Peter Bushunow, Peter Loud, Renuka Iyer & Nikhil Khushalani. (2020) Pralatrexate in Combination with Oxaliplatin in Advanced Esophagogastric Cancer: A Phase II Trial with Predictive Molecular Correlates. Molecular Cancer Therapeutics 19:1, pages 304-311.
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Daniela Barone, Letizia Cito, Giuseppina Tommonaro, Agnese A. Abate, Danila Penon, Rocco De Prisco, Antonella Penon, Iris M. Forte, Elisabetta Benedetti, Annamaria Cimini, Paola Indovina, Barbara Nicolaus, Francesca Pentimalli & Antonio Giordano. (2017) Antitumoral potential, antioxidant activity and carotenoid content of two Southern Italy tomato cultivars extracts: San Marzano and Corbarino. Journal of Cellular Physiology 233:2, pages 1266-1277.
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Somnath Mukherjee, Christopher Nicholas Hurt, Sarah Gwynne, David Sebag-Montefiore, Ganesh Radhakrishna, Simon Gollins, Maria Hawkins, Heike I. Grabsch, Gareth Jones, Stephen Falk, Ricky Sharma, Andrew Bateman, Rajarshi Roy, Ruby Ray, Jo Canham, Gareth Griffiths, Tim Maughan & Tom Crosby. (2017) NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma. European Journal of Cancer 74, pages 38-46.
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Somnath Mukherjee, Christopher N Hurt, Sarah Gwynne, Andrew Bateman, Simon Gollins, Ganesh Radhakrishna, Maria Hawkins, Jo Canham, Wyn Lewis, Heike I Grabsch, Ricky A Sharma, Wendy Wade, Rhydian Maggs, Bethan Tranter, Ashley Roberts, David Sebag-Montefiore, Timothy Maughan, Gareth Griffiths & Tom Crosby. (2015) NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma. BMC Cancer 15:1.
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S. Gwynne, S. Falk, S. Gollins, L. Wills, A. Bateman, S. Cummins, H. Grabsch, M.A. Hawkins, R. Maggs, S. Mukherjee, G. Radhakrishna, R. Roy, R.A. Sharma, E. Spezi & T. Crosby. (2013) Oesophageal Chemoradiotherapy in the UK—Current Practice and Future Directions. Clinical Oncology 25:6, pages 368-377.
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Esme J. Hill, Nils H. Nicolay, Mark R. Middleton & Ricky A. Sharma. (2012) Oxaliplatin as a radiosensitiser for upper and lower gastrointestinal tract malignancies: What have we learned from a decade of translational research?. Critical Reviews in Oncology/Hematology 83:3, pages 353-387.
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E. Gabriela Chiorean, Sonal Sanghani, Marissa A. Schiel, Menggang Yu, Matthew Burns, Yan Tong, David T. Hinkle, Nicki Coleman, Bruce Robb, Julia LeBlanc, Romnee Clark, Jose Bufill, Colleen Curie, Patrick J. Loehrer & Higinia Cardenes. (2012) Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53. Cancer Chemotherapy and Pharmacology 70:1, pages 25-32.
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S. Gwynne, C. Hurt, M. Evans, C. Holden, L. Vout & T. Crosby. (2011) Definitive Chemoradiation for Oesophageal Cancer — a Standard of Care in Patients with Non-metastatic Oesophageal Cancer. Clinical Oncology 23:3, pages 182-188.
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Kilian S. May, Gary Y. Yang & Nikhil I. Khushalani. (2011) The Role of Radiation in the Perioperative Treatment of Esophagogastric Cancer. Current Treatment Options in Oncology 12:1, pages 61-71.
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