Citations (47)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Rodolfo Daniel Ávila-Avilés & J. Manuel Hernández-Hernández. (2023) Ligand- and structure-based identification of GPER-binding small molecules. Molecular Simulation 49:5, pages 489-496.
Read now
Read now
Kuldeep K. Roy. (2022) Structural basis for the binding of a selective inverse agonist AF64394 with the human G-protein coupled receptor 3 (GPR3). Journal of Biomolecular Structure and Dynamics 40:20, pages 10181-10190.
Read now
Read now
Shafi Ullah Khan, Nafees Ahemad, Lay-Hong Chuah, Rakesh Naidu & Thet Thet Htar. (2022) G protein-coupled estrogen receptor-1: homology modeling approaches and application in screening new GPER-1 modulators. Journal of Biomolecular Structure and Dynamics 40:7, pages 3325-3335.
Read now
Read now
Marlet Martínez-Archundia, José Correa-Basurto, Sarita Montaño & Jorge L. Rosas-Trigueros. (2019) Studying the collective motions of the adenosine A2A receptor as a result of ligand binding using principal component analysis. Journal of Biomolecular Structure and Dynamics 37:18, pages 4685-4700.
Read now
Read now
Sarita Montaño, Esther Orozco, José Correa-Basurto, Martiniano Bello, Bibiana Chávez-Munguía & Abigail Betanzos. (2017) Heterodimerization of the Entamoeba histolytica EhCPADH virulence complex through molecular dynamics and protein–protein docking. Journal of Biomolecular Structure and Dynamics 35:3, pages 486-503.
Read now
Read now
Leonardo G. Ferreira, Glaucius Oliva & Adriano D. Andricopulo. (2016) Protein-protein interaction inhibitors: advances in anticancer drug design. Expert Opinion on Drug Discovery 11:10, pages 957-968.
Read now
Read now
Articles from other publishers (41)
Hanyu Yang, Zhiwei Zhang, Qian Liu, Jie Yu, Chongjin Liu & Wencai Lu. (2023) Identification of Dual-Target Inhibitors for Epidermal Growth Factor Receptor and AKT: Virtual Screening Based on Structure and Molecular Dynamics Study. Molecules 28:22, pages 7607.
Crossref
Crossref
Mariana Segovia-Mendoza, Elahe Mirzaei, Heriberto Prado-Garcia, Luis D. Miranda, Alejandra Figueroa & Cristina Lemini. (2022) The Interplay of GPER1 with 17β-Aminoestrogens in the Regulation of the Proliferation of Cervical and Breast Cancer Cells: A Pharmacological Approach. International Journal of Environmental Research and Public Health 19:19, pages 12361.
Crossref
Crossref
Karla Mariana Peña‑Gutiérrez, Karina Hernández‑Ortega, Claudia Bello‑Alvarez & Ignacio Camacho‑Arroyo. (2022) Expression and estrogen regulation of G protein‑coupled estrogen receptor in human glioblastoma cells. Oncology Letters 24:5.
Crossref
Crossref
Eliud Morales Dávila, Felipe Patricio, Mariana Rebolledo-Bustillo, David Garcia-Gomez, Juan Carlos Garcia Hernandez, Brenda L. Sanchez-Gaytan, Ilhuicamina Daniel Limón & Jose Manuel Perez-Aguilar. (2022) Interacting binding insights and conformational consequences of the differential activity of cannabidiol with two endocannabinoid-activated G-protein-coupled receptors. Frontiers in Pharmacology 13.
Crossref
Crossref
Melvin E. Andersen. (2022) Assessing modes of action, measures of tissue dose and human relevance of rodent toxicity endpoints with octamethylcyclotetrasiloxane (D4). Toxicology Letters 357, pages 57-72.
Crossref
Crossref
Arman Safavi, Elaheh Sadat Ghodousi, Mehdi Ghavamizadeh, Mohamad Sabaghan, Omid Azadbakht, Ali veisi, Hossein Babaei, Zahra Nazeri, Mehrnaz Karimi Darabi & Vahid Zarezade. (2021) Computational investigation of novel farnesyltransferase inhibitors using 3D-QSAR pharmacophore modeling, virtual screening, molecular docking and molecular dynamics simulation studies: A new insight into cancer treatment. Journal of Molecular Structure 1241, pages 130667.
Crossref
Crossref
Ashley Ryan Vidad, Stephen Macaspac & Ho Leung Ng. (2021) Locating ligand binding sites in G-protein coupled receptors using combined information from docking and sequence conservation. PeerJ 9, pages e12219.
Crossref
Crossref
Alexander Kalinkovich & Gregory Livshits. (2021) Biased and allosteric modulation of bone cell-expressing G protein-coupled receptors as a novel approach to osteoporosis therapy. Pharmacological Research 171, pages 105794.
Crossref
Crossref
Naoko Honma, Yoko Matsuda & Tetuo Mikami. (2021) Carcinogenesis of Triple-Negative Breast Cancer and Sex Steroid Hormones. Cancers 13:11, pages 2588.
Crossref
Crossref
Giulia D’Arrigo, Eleonora Gianquinto, Giulia Rossetti, Gabriele Cruciani, Stefano Lorenzetti & Francesca Spyrakis. (2021) Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction. Molecules 26:6, pages 1613.
Crossref
Crossref
David Méndez-Luna, Loreley Araceli Morelos-Garnica, Juan Benjamín García-Vázquez, Martiniano Bello, Itzia Irene Padilla-Martínez, Manuel Jonathan Fragoso-Vázquez, Alfonso Dueñas González, Nuria De Pedro, José Antonio Gómez-Vidal, Humberto Lubriel Mendoza-Figueroa & José Correa-Basurto. (2021) Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells. Pharmaceuticals 14:1, pages 49.
Crossref
Crossref
Milad Rouhimoghadam, Anh S. Lu, Aliasger K. Salem & Edward J. Filardo. (2020) Therapeutic Perspectives on the Modulation of G-Protein Coupled Estrogen Receptor, GPER, Function. Frontiers in Endocrinology 11.
Crossref
Crossref
Chelsea DeLeon, David Q.-H. Wang & Christopher K. Arnatt. (2020) G Protein-Coupled Estrogen Receptor, GPER1, Offers a Novel Target for the Treatment of Digestive Diseases. Frontiers in Endocrinology 11.
Crossref
Crossref
Anna Helena Mazurek, Łukasz Szeleszczuk, Thomas Simonson & Dariusz Maciej Pisklak. (2020) Application of Various Molecular Modelling Methods in the Study of Estrogens and Xenoestrogens. International Journal of Molecular Sciences 21:17, pages 6411.
Crossref
Crossref
Xiaoya Ji, Na Li, Mei Ma, Kaifeng Rao, Rong Yang & Zijian Wang. (2020) Tricresyl phosphate isomers exert estrogenic effects via G protein-coupled estrogen receptor-mediated pathways. Environmental Pollution 264, pages 114747.
Crossref
Crossref
Séverine Périan & Jean-Marc Vanacker. (2020) GPER as a Receptor for Endocrine-Disrupting Chemicals (EDCs). Frontiers in Endocrinology 11.
Crossref
Crossref
Fedora Grande, Maria A. Occhiuzzi, Rosamaria Lappano, Francesca Cirillo, Rita Guzzi, Antonio Garofalo, Yves Jacquot, Marcello Maggiolini & Bruno Rizzuti. (2020) Computational Approaches for the Discovery of GPER Targeting Compounds. Frontiers in Endocrinology 11.
Crossref
Crossref
Chelsea DeLeon, Helen H. Wang, Joseph Gunn, McKenna Wilhelm, Aidan Cole, Stacy Arnett, David Q-H. Wang & Christopher K. Arnatt. (2020) A novel GPER antagonist protects against the formation of estrogen-induced cholesterol gallstones in female mice. Journal of Lipid Research 61:5, pages 767-777.
Crossref
Crossref
Liliana Reyes-Vázquez, A. José Alberto Hernández & Emma S. Calderón-Aranda. (2020) Role of aromatase activation on sodium arsenite-induced proliferation, migration, and invasion of MDA-MB-231 and MDA-MB-453 breast cancer cell lines. Toxicology 437, pages 152440.
Crossref
Crossref
Ali Noroozi-Aghideh, Arman Safavi, Elaheh Sadat Ghodousi, Mohsen Rajaeinejad & Pooria Taghavi Moghaddam. (2020) Homology Modeling and Molecular Docking of hABCC3/MRP3 with Chemotherapeutic Agents in Acute Leukemia. Jundishapur Journal of Natural Pharmaceutical Products 15:2.
Crossref
Crossref
Francesca Cirillo, Rosamaria Lappano, Leonardo Bruno, Bruno Rizzuti, Fedora Grande, Rita Guzzi, Sara Briguori, Anna Maria Miglietta, Miki Nakajima, Maria Teresa Di Martino & Marcello Maggiolini. (2019) AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs). Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Crossref
Peter D. Evans. (2019) Aldosterone, STX and amyloid-β1-42 peptides modulate GPER (GPR30) signalling in an embryonic mouse hippocampal cell line (mHippoE-18). Molecular and Cellular Endocrinology 496, pages 110537.
Crossref
Crossref
Martiniano Bello, David Méndez-Luna, Viviana Sarmiento, José Correa Basurto, Nayelli Najera, Francisco Villarreal & Guillermo Ceballos. (2019) Structural and energetic basis for novel epicatechin derivatives acting as GPER agonists through the MMGBSA method. The Journal of Steroid Biochemistry and Molecular Biology 189, pages 176-186.
Crossref
Crossref
Shafi Ullah Khan, Nafees Ahemad, Lay-Hong Chuah, Rakesh Naidu & Thet Thet Htar. (2019) Sequential ligand- and structure-based virtual screening approach for the identification of potential G protein-coupled estrogen receptor-1 (GPER-1) modulators. RSC Advances 9:5, pages 2525-2538.
Crossref
Crossref
Rosamaria Lappano, Yves Jacquot & Marcello Maggiolini. (2018) GPCR Modulation in Breast Cancer. International Journal of Molecular Sciences 19:12, pages 3840.
Crossref
Crossref
Ruby Vajaria & Nandini Vasudevan. (2018) Is the membrane estrogen receptor, GPER1, a promiscuous receptor that modulates nuclear estrogen receptor-mediated functions in the brain?. Hormones and Behavior 104, pages 165-172.
Crossref
Crossref
Lin-Ying Cao, Xiao-Min Ren, Yu Yang, Bin Wan, Liang-Hong Guo, De Chen & Yong Fan. (2018) Hydroxylated Polybrominated Biphenyl Ethers Exert Estrogenic Effects via Non-Genomic G Protein–Coupled Estrogen Receptor Mediated Pathways. Environmental Health Perspectives 126:5.
Crossref
Crossref
Amanda A Krentzel, Matheus Macedo-Lima, Maaya Z Ikeda & Luke Remage-Healey. (2018) A Membrane G-Protein-Coupled Estrogen Receptor Is Necessary but Not Sufficient for Sex Differences in Zebra Finch Auditory Coding. Endocrinology 159:3, pages 1360-1376.
Crossref
Crossref
Viviana Sarmiento, Israel Ramirez-Sanchez, Aldo Moreno-Ulloa, Diego Romero-Perez, Daniel Chávez, Miguel Ortiz, Nayelli Najera, Jose Correa-Basurto, Francisco Villarreal & Guillermo Ceballos. (2018) Synthesis of novel (−)-epicatechin derivatives as potential endothelial GPER agonists: Evaluation of biological effects. Bioorganic & Medicinal Chemistry Letters 28:4, pages 658-663.
Crossref
Crossref
Marília I. Figueira, Henrique J. Cardoso & Sílvia Socorro. 2018. Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs. Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs
59
117
.
Lin-Ying Cao, Xiao-Min Ren, Chuan-Hai Li, Jing Zhang, Wei-Ping Qin, Yu Yang, Bin Wan & Liang-Hong Guo. (2017) Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway. Environmental Science & Technology 51:19, pages 11423-11430.
Crossref
Crossref
Li-Juan Deng, Chen Cheng, Jun Wu, Cai-Hua Wang, Hai-Bing Zhou & Jian Huang. (2017) Oxabicycloheptene Sulfonate Protects Against β-Amyloid-induced Toxicity by Activation of PI3K/Akt and ERK Signaling Pathways Via GPER1 in C6 Cells. Neurochemical Research 42:8, pages 2246-2256.
Crossref
Crossref
Xu Wang, Lian Zhao, Yikui Zhang, Wenxin Ma, Shaimar R. Gonzalez, Jianguo Fan, Friedrich Kretschmer, Tudor C. Badea, Hao-hua Qian & Wai T. Wong. (2017) Tamoxifen Provides Structural and Functional Rescue in Murine Models of Photoreceptor Degeneration. The Journal of Neuroscience 37:12, pages 3294-3310.
Crossref
Crossref
Robert B. Cameron, Craig C. Beeson & Rick G. Schnellmann. (2016) Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases. Journal of Medicinal Chemistry 59:23, pages 10411-10434.
Crossref
Crossref
Agostino Bruno, Francesca Aiello, Gabriele Costantino & Marco Radi. (2016) Homology Modeling, Validation and Dynamics of the G Protein-coupled Estrogen Receptor 1 (GPER-1). Molecular Informatics 35:8-9, pages 333-339.
Crossref
Crossref
David Méndez-Luna, Martiniano Bello & José Correa-Basurto. (2016) Understanding the molecular basis of agonist/antagonist mechanism of GPER1/GPR30 through structural and energetic analyses. The Journal of Steroid Biochemistry and Molecular Biology 158, pages 104-116.
Crossref
Crossref
Camillo Rosano, Marco Ponassi, Maria Francesca Santolla, Assunta Pisano, Lamberto Felli, Adele Vivacqua, Marcello Maggiolini & Rosamaria Lappano. (2015) Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands. The AAPS Journal 18:1, pages 41-46.
Crossref
Crossref
O.J. Zacarías-Lara, D.E. González-Juárez & J. Correa-Basurto. 2016. Epi-Informatics. Epi-Informatics
213
229
.
Aldo Moreno-Ulloa, David Mendez-Luna, Ernesto Beltran-Partida, Carmen Castillo, Gustavo Guevara, Israel Ramirez-Sanchez, José Correa-Basurto, Guillermo Ceballos & Francisco Villarreal. (2015) The effects of (−)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER). Pharmacological Research 100, pages 309-320.
Crossref
Crossref
Urara Nakamura, Faidiban O. Rudolf, Kiran Pandey & Hiroya Kadokawa. (2015) The non-steroidal mycoestrogen zeranol suppresses luteinizing hormone secretion from the anterior pituitary of cattle via the estradiol receptor GPR30 in a rapid, non-genomic manner. Animal Reproduction Science 156, pages 118-127.
Crossref
Crossref
Matthias Barton & Eric R. Prossnitz. (2015) Emerging roles of GPER in diabetes and atherosclerosis. Trends in Endocrinology & Metabolism 26:4, pages 185-192.
Crossref
Crossref