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Original

Circadian Uses of Melatonin in Humans

, M.D., Ph.D., , &
Pages 403-412 | Published online: 07 Jul 2009

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Read on this site (14)

Nandu Goswami, Carolina Abulafia, Daniel Vigo, Maximilian Moser, Germaine Cornelissen & Daniel Cardinali. (2020) Falls Risk, Circadian Rhythms and Melatonin: Current Perspectives. Clinical Interventions in Aging 15, pages 2165-2174.
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Daniel P. Cardinali. (2019) Melatonin as a chronobiotic/cytoprotector: its role in healthy aging. Biological Rhythm Research 50:1, pages 28-45.
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Yuichi Esaki, Tsuyoshi Kitajima, Ippei Takeuchi, Soji Tsuboi, Osamu Furukawa, Masatsugu Moriwaki, Kiyoshi Fujita & Nakao Iwata. (2017) Effect of blue-blocking glasses in major depressive disorder with sleep onset insomnia: A randomized, double-blind, placebo-controlled study. Chronobiology International 34:6, pages 753-761.
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Gabriela Laste, Isabel Cristina de Macedo, Joanna Ripoll Rozisky, Fernanda Ribeiro da Silva, Wolnei Caumo & Iraci LS Torres. (2012) Melatonin administration reduces inflammatory pain in rats. Journal of Pain Research 5, pages 359-362.
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Berndt Eckerberg, Arne Lowden, Roberta Nagai & Torbjörn Åkerstedt. (2012) Melatonin Treatment Effects on Adolescent Students' Sleep Timing and Sleepiness in a Placebo-Controlled Crossover Study. Chronobiology International 29:9, pages 1239-1248.
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Masako Kohsaka, Takashi Kanemura, Mitsutaka Taniguchi, Hiroo Kuwahara, Akira Mikami, Kunihisa Kamikawa, Hideki Uno, Atsushi Ogawa, Mitsukuni Murasaki & Yoshiro Sugita. (2011) Efficacy and tolerability of ramelteon in a double-blind, placebo-controlled, crossover study in Japanese patients with chronic primary insomnia. Expert Review of Neurotherapeutics 11:10, pages 1389-1397.
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Robert M. Post. (2008) Promising avenues of therapeutics for bipolar illness. Dialogues in Clinical Neuroscience 10:2, pages 193-201.
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Daniel P Cardinali, Seithikurippu R Pandi-Perumal, Venkataramanujan Srinivasan, D Warren Spence & Ilya Trakht. (2008) Therapeutic potential of melatonin agonists. Expert Review of Endocrinology & Metabolism 3:2, pages 269-279.
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Garance Dispersyn, Laure Pain, Etienne Challet & Yvan Touitou. (2008) General Anesthetics Effects on Circadian Temporal Structure: An Update. Chronobiology International 25:6, pages 835-850.
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Konstantin V. Danilenko, Igor L. Plisov, Marc Hébert, Kurt Kräuchi & Anna Wirz‐Justice. (2008) Influence of Timed Nutrient Diet on Depression and Light Sensitivity in Seasonal Affective Disorder. Chronobiology International 25:1, pages 51-64.
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JamesE. Jan, MichaelB. Wasdell, MargaretD. Weiss & RogerD. Freeman. (2007) What is the correct dose of melatonin in sleep therapy?. Biological Rhythm Research 38:2, pages 85-86.
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Barbara Griefahn, Jürgen Groß & Sibylle Robens. (2007) Quantification of Circadian Phase Shifts with the Cross‐Correlation Technique. Chronobiology International 24:3, pages 449-461.
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Articles from other publishers (82)

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Martijn Arns, J.J. Sandra Kooij & Andrew N. Coogan. (2021) Review: Identification and Management of Circadian Rhythm Sleep Disorders as a Transdiagnostic Feature in Child and Adolescent Psychiatry. Journal of the American Academy of Child & Adolescent Psychiatry 60:9, pages 1085-1095.
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Santiago Pérez-Lloret & Daniel P. Cardinali. (2021) Melatonin as a Chronobiotic and Cytoprotective Agent in Parkinson’s Disease. Frontiers in Pharmacology 12.
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Beatriz Bano‐Otalora, Juan Antonio Madrid & Maria Angeles Rol. (2019) Melatonin alleviates circadian system disruption induced by chronic shifts of the light‐dark cycle in Octodon degus . Journal of Pineal Research 68:1.
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Karim Fifel & Aleksandar Videnovic. (2019) Chronotherapies for Parkinson’s disease. Progress in Neurobiology 174, pages 16-27.
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John A. Caldwell, J. Lynn Caldwell, Lauren A. Thompson & Harris R. Lieberman. (2019) Fatigue and its management in the workplace. Neuroscience & Biobehavioral Reviews 96, pages 272-289.
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Emmanuelle A. D. Schindler, Ryan M. Wallace, Jordan A. Sloshower & Deepak C. D’Souza. (2018) Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics. Frontiers in Pharmacology 9.
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Mara E.J. Bouwmans, Adriene M. Beltz, Elisabeth H. Bos, Albertine J. Oldehinkel, Peter de Jonge & Peter C.M. Molenaar. (2018) The person-specific interplay of melatonin, affect, and fatigue in the context of sleep and depression. Personality and Individual Differences 123, pages 163-170.
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Gregory M. Brown, Roger S. McIntyre, Joshua Rosenblat & Rüdiger Hardeland. (2018) Depressive disorders: Processes leading to neurogeneration and potential novel treatments. Progress in Neuro-Psychopharmacology and Biological Psychiatry 80, pages 189-204.
Crossref
Daniel Pedro CardinaliDaniel Pedro Cardinali. 2018. Autonomic Nervous System. Autonomic Nervous System 313 373 .
Megan Alston, Sean W. Cain & Shantha M. W. Rajaratnam. 2019. Sleep-Wake Neurobiology and Pharmacology. Sleep-Wake Neurobiology and Pharmacology 305 319 .
B. Nussbaumer-Streit, D. Winkler, M. Spies, S. Kasper & E. Pjrek. (2017) Prevention of seasonal affective disorder in daily clinical practice: results of a survey in German-speaking countries. BMC Psychiatry 17:1.
Crossref
Jacky Au & John Reece. (2017) The relationship between chronotype and depressive symptoms: A meta-analysis. Journal of Affective Disorders 218, pages 93-104.
Crossref
Karim Fifel. (2017) Alterations of the circadian system in Parkinson's disease patients. Movement Disorders 32:5, pages 682-692.
Crossref
A.J. Lewy. 2017. Reference Module in Neuroscience and Biobehavioral Psychology. Reference Module in Neuroscience and Biobehavioral Psychology.
T.I. Bron, D. Bijlenga, J.J.S. Kooij, S.W.N. Vogel, D. Wynchank, A.T.F. Beekman & B.W.J.H. Penninx. (2016) Attention-deficit hyperactivity disorder symptoms add risk to circadian rhythm sleep problems in depression and anxiety. Journal of Affective Disorders 200, pages 74-81.
Crossref
Justyna Paprocka, Marek Kijonka, Marcin Pęcka & Maria Sokół. (2016) Melatonin in Epilepsy: A New Mathematical Model of Diurnal Secretion. International Journal of Endocrinology 2016, pages 1-8.
Crossref
Daniel Pedro CardinaliDaniel Pedro Cardinali. 2016. Ma Vie en Noir. Ma Vie en Noir 155 169 .
Angela Kaminski-Hartenthaler, Barbara Nussbaumer, Catherine A Forneris, Laura C Morgan, Bradley N Gaynes, Jeffrey H Sonis, Amy Greenblatt, Jörg Wipplinger, Linda J Lux, Dietmar Winkler, Megan G Van Noord, Julia Hofmann & Gerald Gartlehner. (2015) Melatonin and agomelatine for preventing seasonal affective disorder. Cochrane Database of Systematic Reviews.
Crossref
C. Chaufton & S. Bioulac. (2015) Le syndrome de retard de phase : une expérience personnelle de prise en charge associant lumière et mélatonine. Médecine du Sommeil 12:3, pages 103-115.
Crossref
Anders Johnsson, Charlotte Helfrich-Förster & Wolfgang Engelmann. 2015. Photobiology. Photobiology 243 297 .
Maria Bonmati-Carrion, Raquel Arguelles-Prieto, Maria Martinez-Madrid, Russel Reiter, Ruediger Hardeland, Maria Rol & Juan Madrid. (2014) Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure. International Journal of Molecular Sciences 15:12, pages 23448-23500.
Crossref
Marc A. Seifman, Keith Gomes, Phuong N. Nguyen, Michael Bailey, Jeffrey V. Rosenfeld, David J. Cooper & Maria Cristina Morganti-Kossmann. (2014) Measurement of Serum Melatonin in Intensive Care Unit Patients: Changes in Traumatic Brain Injury, Trauma, and Medical Conditions. Frontiers in Neurology 5.
Crossref
Panteleimon D. MavroudisSiobhan A. Corbett, Steven E. Calvano & Ioannis P. Androulakis. (2014) Mathematical modeling of light-mediated HPA axis activity and downstream implications on the entrainment of peripheral clock genes. Physiological Genomics 46:20, pages 766-778.
Crossref
Angela Kaminski-Hartenthaler, Barbara Nussbaumer, Catherine A Forneris, Laura C Morgan, Bradley N Gaynes, Jeffrey H Sonis, Amy Greenblatt, Jörg Wipplinger, Linda J Lux, Julia Hofmann, Megan G Van Noord, Dietmar Winkler & Gerald Gartlehner. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Ludmila Gaspar, Maan van de Werken, Anne-Sophie Johansson, Ermanno Moriggi, Björn Owe-Larsson, Janwillem W. H. Kocks, Gabriella B. Lundkvist, Marijke C. M. Gordijn & Steven A. Brown. (2014) Human cellular differences in cAMP - CREB signaling correlate with light-dependent melatonin suppression and bipolar disorder. European Journal of Neuroscience 40:1, pages 2206-2215.
Crossref
Tina M. Burke, Rachel R. Markwald, Evan D. Chinoy, Jesse A. Snider, Sara C. Bessman, Christopher M. Jung & Kenneth P. WrightJr.Jr.. (2013) Combination of Light and Melatonin Time Cues for Phase Advancing the Human Circadian Clock. Sleep 36:11, pages 1617-1624.
Crossref
Mariangela Rondanelli, Milena Anna Faliva, Simone Perna & Neldo Antoniello. (2013) Update on the role of melatonin in the prevention of cancer tumorigenesis and in the management of cancer correlates, such as sleep-wake and mood disturbances: review and remarks. Aging Clinical and Experimental Research 25:5, pages 499-510.
Crossref
A.J. Lewy. 2013. Encyclopedia of Sleep. Encyclopedia of Sleep 126 137 .
J. J. Sandra KooijJ. J. Sandra Kooij. 2013. Adult ADHD. Adult ADHD 101 168 .
J. J. Sandra KooijJ. J. Sandra Kooij. 2013. Adult ADHD. Adult ADHD 33 96 .
Yoshikazu Takaesu, Yoko Komada & Yuichi Inoue. (2012) Melatonin profile and its relation to circadian rhythm sleep disorders in Angelman syndrome patients. Sleep Medicine 13:9, pages 1164-1170.
Crossref
Qiuping Pearl Zhou, Lorena Jung & Kathy C. Richards. (2012) The Management of Sleep and Circadian Disturbance in Patients with Dementia. Current Neurology and Neuroscience Reports 12:2, pages 193-204.
Crossref
Noga Kronfeld-Schor & Haim Einat. (2012) Circadian rhythms and depression: Human psychopathology and animal models. Neuropharmacology 62:1, pages 101-114.
Crossref
Michael H. Smolensky, Ronald A. Siegel, Erhard Haus, Ramon Hermida & Francesco Portaluppi. 2012. Fundamentals and Applications of Controlled Release Drug Delivery. Fundamentals and Applications of Controlled Release Drug Delivery 359 443 .
Jörg H. Stehle, Anastasia Saade, Oliver Rawashdeh, Katrin Ackermann, Antje Jilg, Tamás Sebestény & Erik Maronde. (2011) A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases. Journal of Pineal Research 51:1, pages 17-43.
Crossref
Ana Barion. (2011) Circadian Rhythm Sleep Disorders. Disease-a-Month 57:8, pages 423-437.
Crossref
Eduardo Alves de Almeida, Paolo Di Mascio, Tatsuo Harumi, D. Warren Spence, Adam Moscovitch, Rüdiger Hardeland, Daniel P. Cardinali, Gregory M. Brown & S. R. Pandi-Perumal. (2010) Measurement of melatonin in body fluids: Standards, protocols and procedures. Child's Nervous System 27:6, pages 879-891.
Crossref
G. Bersani, D. Liberati, A. Rasa, E. Polli, M. Ciuffa, L. Limpido, D. Russo, D. Marconi & F. Pacitti. (2020) Premorbid sleep, appetite, energy, and cognitive circadian profile in patients with depressive disorders. European Psychiatry 25:8, pages 461-464.
Crossref
Venkatramanujam Srinivasan, Jarnail Singh, Seithikurippu R. Pandi-Perumal, Gregory M. Brown, David Warren Spence & Daniel P. Cardinali. (2010) Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs. Advances in Therapy 27:11, pages 796-813.
Crossref
Ingeborg M. van Geijlswijk, Kristiaan B. van der Heijden, A. C. G. Egberts, Hubert P. L. M. Korzilius & Marcel G. Smits. (2010) Dose finding of melatonin for chronic idiopathic childhood sleep onset insomnia: an RCT. Psychopharmacology 212:3, pages 379-391.
Crossref
G. Dispersyn, D. Chassard & L. Pain. (2010) L’anesthésie-réanimation et les rythmes biologiques. Annales Françaises d'Anesthésie et de Réanimation 29:6, pages 470-477.
Crossref
Venkataramanujam Srinivasan, Seithikurippu R. Pandi-Perumal, D.Warren Spence, Adam Moscovitch, Ilya Trakht, Gregory M. Brown & Daniel P. Cardinali. (2010) Potential use of melatonergic drugs in analgesia: Mechanisms of action. Brain Research Bulletin 81:4-5, pages 362-371.
Crossref
David K. Welsh & Louis J. Ptácek. 2010. Principles and Practice of Geriatric Sleep Medicine. Principles and Practice of Geriatric Sleep Medicine 131 142 .
Daniel P. Cardinali & Michal Karasek. 2010. Principles and Practice of Geriatric Sleep Medicine. Principles and Practice of Geriatric Sleep Medicine 97 106 .
Gregory M. Brown, Seithikurippu R. Pandi-Perumal, Ilya Trakht & Daniel P. Cardinali. (2009) Melatonin and its relevance to jet lag. Travel Medicine and Infectious Disease 7:2, pages 69-81.
Crossref
Bruce Charles, Yvan Touitou & Brahim Selmaoui. (2009) A population Pharmacokinetic Turnover and Surge‐Function Model for Describing Melatonin Biological Rhythm in Healthy Male Subjects. Journal of Pharmaceutical Sciences 98:2, pages 782-790.
Crossref
James E. Jan, Russel J. Reiter, Michael B. Wasdell & Martin Bax. (2009) The role of the thalamus in sleep, pineal melatonin production, and circadian rhythm sleep disorders. Journal of Pineal Research 46:1, pages 1-7.
Crossref
R.T. Rubin & B.J. Carroll. 2009. Hormones, Brain and Behavior. Hormones, Brain and Behavior 2899 2928 .
Christopher A. Alford. 2009. Drugs, Driving and Traffic Safety. Drugs, Driving and Traffic Safety 207 232 .
Kenneth Wright, Christopher Drake & Steven Lockley. 2008. Handbook of Sleep Disorders, Second Edition. Handbook of Sleep Disorders, Second Edition 147 173 .
Jian-hua Yan, Hao-ran Su, Jean A Boutin, M Pierre Renard & Ming-wei Wang. (2008) High-throughput screening assay for new ligands at human melatonin receptors. Acta Pharmacologica Sinica 29:12, pages 1515-1521.
Crossref
T. Danel, O. Cottencin, L. Tisserand & Y. Touitou. (2008) Inversion of Melatonin Circadian Rhythm in Chronic Alcoholic Patients during Withdrawal: Preliminary Study on Seven Patients. Alcohol and Alcoholism 44:1, pages 42-45.
Crossref
Anne Germain & David J. Kupfer. (2008) Circadian rhythm disturbances in depression. Human Psychopharmacology: Clinical and Experimental 23:7, pages 571-585.
Crossref
Christopher M. Ciarleglio, Kelli K. Ryckman, Stein V. Servick, Akiko Hida, Sam Robbins, Nancy Wells, Jennifer Hicks, Sydney A. Larson, Joshua P. Wiedermann, Krista Carver, Nalo Hamilton, Kenneth K. Kidd, Judith R. Kidd, Jeffrey R. Smith, Jonathan Friedlaender, Douglas G. McMahon, Scott M. Williams, Marshall L. Summar & Carl Hirschie Johnson. (2008) Genetic Differences in Human Circadian Clock Genes among Worldwide Populations. Journal of Biological Rhythms 23:4, pages 330-340.
Crossref
Seithikurippu R Pandi-Perumal, Ilya Trakht, D Warren Spence, Venkataramanujan Srinivasan, Yaron Dagan & Daniel P Cardinali. (2008) The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disorders. Nature Clinical Practice Neurology 4:8, pages 436-447.
Crossref
John A. Caldwell, J. Lynn Caldwell & Regina M. Schmidt. (2008) Alertness management strategies for operational contexts. Sleep Medicine Reviews 12:4, pages 257-273.
Crossref
James E Jan & Michael B Wasdell. (2008) Letter to the Editor. Developmental Medicine & Child Neurology 50:7, pages 558-558.
Crossref
Y. Touitou. (2008) Dysfonctionnements de l’horloge biologique et leurs traitements. Annales Pharmaceutiques Françaises 66:3, pages 146-157.
Crossref
Denis Martinez, Maria do Carmo Sfreddo Lenz & Luiz Menna-Barreto. (2008) Diagnóstico dos transtornos do sono relacionados ao ritmo circadiano. Jornal Brasileiro de Pneumologia 34:3, pages 173-180.
Crossref
Stephen A. Bezruchka. 2008. The Travel and Tropical Medicine Manual. The Travel and Tropical Medicine Manual 132 151 .
Daniel P. Cardinali, Seithikurippu R. Pandi-Perumal & Venkataramanujan Srinivasan. 2008. Serotonin and Sleep: Molecular, Functional and Clinical Aspects. Serotonin and Sleep: Molecular, Functional and Clinical Aspects 477 499 .
Chris Alford & Sue Wilson. 2008. Sleep and Quality of Life in Clinical Medicine. Sleep and Quality of Life in Clinical Medicine 53 66 .
Alfred J. Lewy. (2007) Current Understanding and Future Implications of the Circadian Uses of Melatonin, a Neurohormone Discovered by Aaron B. Lerner. Journal of Investigative Dermatology 127:9, pages 2082-2085.
Crossref
Michael H. Smolensky & Nicholas A. Peppas. (2007) Chronobiology, drug delivery, and chronotherapeutics. Advanced Drug Delivery Reviews 59:9-10, pages 828-851.
Crossref
Y. Touitou. (2007) Troubles du sommeil et hypnotiques. Annales Pharmaceutiques Françaises 65:4, pages 230-238.
Crossref
A. J. Lewy. (2007) Melatonin and Human Chronobiology. Cold Spring Harbor Symposia on Quantitative Biology 72:1, pages 623-636.
Crossref

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