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ORIGINAL ARTICLE

Pregnancy‐associated plasma protein A: A biomarker in acute ST‐elevation myocardial infarction (STEMI)

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Pages 221-228 | Received 06 Jul 2005, Accepted 12 Dec 2005, Published online: 26 Aug 2009

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Christos A. Papanastasiou, Damianos G. Kokkinidis, Evangelos K. Oikonomou, Vasileios G. Mantziaris, T. Raymond Foley, Theodoros D. Karamitsos, Stephen W. Waldo & Ehrin J. Armstrong. (2018) Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review. Biomarkers 23:1, pages 1-9.
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Yuan-Lin Guo & Jian-Jun Li. (2013) Biomarkers for the prediction of acute ongoing arterial plaque rupture. Research Reports in Clinical Cardiology 4, pages 107-113.
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Mikkel Schoos, Kasper Iversen, Ane Teisner, Børge Teisner, Pia Thaning, Anette Kliem, Peer Grande & Peter Clemmensen. (2009) Release patterns of pregnancy‐associated plasma protein A in patients with acute coronary syndromes assessed by an optimized monoclonal antibody assay. Scandinavian Journal of Clinical and Laboratory Investigation 69:1, pages 121-127.
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Susann Eriksson, Saara Wittfooth & Kim Pettersson. (2006) Present and Future Biochemical Markers for Detection of Acute Coronary Syndrome. Critical Reviews in Clinical Laboratory Sciences 43:5-6, pages 427-495.
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Articles from other publishers (34)

Joyce Lim, Allan Davies, Stephen Brienesse, Nishani S. Mabotuwana & Andrew Boyle. (2023) Inflammatory cell response following ST-elevation myocardial infarction treated with primary percutaneous coronary intervention and its impact on cardiovascular outcomes: A systematic review and meta-analysis. International Journal of Cardiology 376, pages 1-10.
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Sreenu Thupakula, Shiva Shankar Reddy Nimmala, Haritha Ravula, Sudhakar Chekuri & Raju Padiya. (2022) Emerging biomarkers for the detection of cardiovascular diseases. The Egyptian Heart Journal 74:1.
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Nilsson, Kastrup, Sajadieh, Boje Jensen, Kjøller, Kolmos, Wuopio, Nowak, Larsson, Jakobsen, Winkel, Gluud, Iversen, Ärnlöv & Carlsson. (2020) Pregnancy Associated Plasma Protein-A as a Cardiovascular Risk Marker in Patients with Stable Coronary Heart Disease During 10 Years Follow-Up—A CLARICOR Trial Sub-Study. Journal of Clinical Medicine 9:1, pages 265.
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Rikke Hjortebjerg. (2018) IGFBP-4 and PAPP-A in normal physiology and disease. Growth Hormone & IGF Research 41, pages 7-22.
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Özgür TATLI, Yunus Karaca, İsmet Durmuş, Sinan Şahin, Ahmet Menteşe, Suha Türkmen, Abdulkadir Gündüz & Süleyman Türedi. (2017) Göğüs ağrısı olan hastalarda gebelikle ilişkili plazma protein a (PAPP-a) ve iskemi modifiye albümin değerinin karşılaştırılması. TURKISH JOURNAL of CLINICS and LABORATORY.
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Plinio Cirillo, Stefano Conte, Grazia Pellegrino, Francesca Ziviello, Giusi Barra, Raffaele De Palma, Antonio Leonardi & Bruno Trimarco. (2016) Pregnancy-associated plasma protein-A promotes TF procoagulant activity in human endothelial cells by Akt–NF-κB axis. Journal of Thrombosis and Thrombolysis 42:2, pages 225-232.
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SABESAN MYTHILI & NARASIMHAN MALATHI. (2015) Diagnostic markers of acute myocardial infarction. Biomedical Reports 3:6, pages 743-748.
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Elvin Zengin, Christoph Sinning, Tanja Zeller, Hans-J Rupprecht, Renate B Schnabel, Karl-J Lackner, Stefan Blankenberg, Dirk Westermann & Christoph Bickel. (2015) The utility of pregnancy-associated plasma protein A for determination of prognosis in a cohort of patients with coronary artery disease. Biomarkers in Medicine 9:8, pages 731-741.
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Rikke Hjortebjerg, Søren Lindberg, Søren Hoffmann, Jan S. Jensen, Claus Oxvig, Mette Bjerre & Jan Frystyk. (2015) PAPP-A and IGFBP-4 fragment levels in patients with ST-elevation myocardial infarction treated with heparin and PCI. Clinical Biochemistry 48:4-5, pages 322-328.
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P. K. Shah. (2014) Biomarkers of Plaque Instability. Current Cardiology Reports 16:12.
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Camilla H B Jespersen, Kirstine R Vestergaard, Morten Schou, Børge Teisner, Jens P Goetze & Kasper Iversen. (2014) Pregnancy-associated plasma protein-A and the vulnerable plaque. Biomarkers in Medicine 8:8, pages 1033-1047.
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Nguyen T. Nguyen, Xiaolin Zhang, Cathy Wu, Richard A. Lange, Robert J. Chilton, Merry L. Lindsey & Yu-Fang Jin. (2014) Integrative Computational and Experimental Approaches to Establish a Post-Myocardial Infarction Knowledge Map. PLoS Computational Biology 10:3, pages e1003472.
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Tanja Savukoski, Tuomo Ilva, Juha Lund, Pekka Porela, Noora Ristiniemi, Saara Wittfooth & Kim Pettersson. (2014) Autoantibody prevalence with an improved immunoassay for detecting cardiac troponin-specific autoantibodies. Clinical Chemistry and Laboratory Medicine (CCLM) 52:2.
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Yuehua Li, Chenghui Zhou, Xianliang Zhou, Lei Song & Rutai Hui. (2013) PAPP-A in cardiac and non-cardiac conditions. Clinica Chimica Acta 417, pages 67-72.
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Xiao-fan Wu, Xiao-hui Liu, Jian-zeng Dong, Lu-ya Wang, Ya Yang, Shao-ping Nie, Yin Zhang & Chang-sheng Ma. (2013) Pregnancy-Associated Plasma Protein-A as a Marker of Culprit Lesion Instability in Unstable Angina Patients: An Intravascular Ultrasound Study. Cardiology 126:4, pages 244-251.
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Petr Hájek, Milan MacekSr.Sr., Martina Pešková, Marie Hladíková, Eva Hansvenclová, Martin Malý, Josef Veselka & Alice Krebsová. (2012) High positive predictive value of PAPP-A for acute coronary syndrome diagnosis in heparin-naïve patients. Journal of Thrombosis and Thrombolysis 34:1, pages 99-105.
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N Moghadasian & Mohammed EskinChantal Bassett, Richelle McCullough, Justin Deniset, rea Edel, rew Francis, Delfin Rodriguez-Leyva, Mirna Chahine & Grant Pierce. 2012. Functional Foods and Cardiovascular Disease. Functional Foods and Cardiovascular Disease 1 28 .
Koji Kumagai, Haruhiko Ohnaka, Fumio Okamoto, Masayuki Yasuda, Hideki Kamegai & Masahide Ohmichi. (2011) Early diagnosis of postpartum acute myocardial infarction with combined use of troponin T and heart-type fatty acid-binding protein rapid assay. Journal of Obstetrics and Gynaecology Research 37:10, pages 1484-1488.
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Jonathan W Waks & Benjamin M Scirica. (2011) Established and novel biomarkers in ST-elevation myocardial infarction. Future Cardiology 7:4, pages 523-546.
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Saara Wittfooth, Risto Tertti, Mauri Lepäntalo, Pekka Porela, Qiu-Ping Qin, Joanna Tynjälä, Outi Inkinen, Juha Perttilä, K.E. Juhani Airaksinen & Kim Pettersson. (2011) Studies on the effects of heparin products on pregnancy-associated plasma protein A. Clinica Chimica Acta 412:3-4, pages 376-381.
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Petr Hájek & Milan Macek. (2010) Pregnancy-associated plasma protein-A in the pathophysiology, diagnosis, and prognosis of coronary heart disease. Cor et Vasa 52:7-8, pages 453-457.
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Juha Lund, Saara Wittfooth, Qiu-Ping Qin, Tuomo Ilva, Pekka Porela, Kari Pulkki, Kim Pettersson & Liisa-Maria Voipio-Pulkki. (2010) Free vs Total Pregnancy-Associated Plasma Protein A (PAPP-A) as a Predictor of 1-Year Outcome in Patients Presenting with Non–ST-Elevation Acute Coronary Syndrome. Clinical Chemistry 56:7, pages 1158-1165.
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Kasper K. Iversen, Morten Dalsgaard, Ane S. Teisner, Mikkel Schoos, Borge Teisner, Henrik Nielsen, Peer Grande & Peter Clemmensen. (2010) Pregnancy-associated plasma protein-a, a marker for outcome in patients suspected for acute coronary syndrome. Clinical Biochemistry 43:10-11, pages 851-857.
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Kasper K. Iversen, Morten Dalsgaard, Ane S. Teisner, Mikkel Schoos, Borge Teisner, Henrik Nielsen, Peter Clemmensen & Peer Grande. (2009) Usefulness of Pregnancy-Associated Plasma Protein A in Patients With Acute Coronary Syndrome. The American Journal of Cardiology 104:11, pages 1465-1471.
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Eline B. Furenes, Harald Arnesen, Svein Solheim, Haakon K. Grøgaard, Pavel Hoffmann & Ingebjørg Seljeflot. (2009) The profile of circulating metalloproteinases after PCI in patients with acute myocardial infarction or stable angina. Thrombosis Research 124:5, pages 560-564.
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Kasper K. Iversen, Ane S. Teisner, Borge Teisner, Anette Kliem, Pia Thanning, Henrik Nielsen, Peter Clemmensen & Peer Grande. (2009) Pregnancy associated plasma protein A, a potential marker for vulnerable plaque in patients with non-ST-segment elevation acute coronary syndrome. Clinical Biochemistry 42:9, pages 828-834.
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Luciano Consuegra-Sanchez, Salim Fredericks & Juan Carlos Kaski. (2009) Pregnancy-associated plasma protein-A (PAPP-A) and cardiovascular risk. Atherosclerosis 203:2, pages 346-352.
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Christian J. Terkelsen, Claus Oxvig, Bjarne L. Nørgaard, Simon Glerup, Tina S. Poulsen, Jens F. Lassen, Holger J. Møller, Leif Thuesen, Erling Falk, Torsten T. Nielsen & Henning R. Andersen. (2009) Temporal Course of Pregnancy-Associated Plasma Protein-A in Angioplasty-Treated ST-Elevation Myocardial Infarction Patients and Potential Significance of Concomitant Heparin Administration. The American Journal of Cardiology 103:1, pages 29-35.
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Kasper Karmark Iversen, Ane Sogaard Teisner, Borge Teisner, Anette Kliem, Morten Bay, Vibeke Kirk, Henrik Nielsen, Soren Boesgaard, Peer Grande & Peter Clemmensen. (2008) Pregnancy-associated plasma protein A in non-cardiac conditions. Clinical Biochemistry 41:7-8, pages 548-553.
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Kasper K. Iversen, Ane S. Teisner, Borge Teisner, Anette Kliem, Pia Thanning, Peer Grande & Peter Clemmensen. (2008) Pregnancy Associated Plasma Protein A, a Novel, Quick, and Sensitive Marker in ST-Elevation Myocardial Infarction. The American Journal of Cardiology 101:10, pages 1389-1394.
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Michael D. Miedema, Cheryl A. Conover, Holly MacDonald, Sean C. Harrington, Dedra Oberg, Daniel Wilson, Timothy D. Henry & Robert S. Schwartz. (2008) Pregnancy-Associated Plasma Protein-A Elevation in Patients With Acute Coronary Syndrome and Subsequent Atorvastatin Therapy. The American Journal of Cardiology 101:1, pages 35-39.
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A. S. Astrup, L. Tarnow, M. Christiansen, P. R. Hansen, H.-H. Parving & P. Rossing. (2007) Pregnancy-associated plasma protein A in a large cohort of Type 1 diabetic patients with and without diabetic nephropathy—a prospective follow-up study. Diabetic Medicine 24:12, pages 1381-1385.
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Qiu-Ping Qin, Saara Wittfooth & Kim Pettersson. (2007) Measurement and clinical significance of circulating PAPP-A in ACS patients. Clinica Chimica Acta 380:1-2, pages 59-67.
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Wolfgang KoenigNatalie Khuseyinova. (2007) Biomarkers of Atherosclerotic Plaque Instability and Rupture. Arteriosclerosis, Thrombosis, and Vascular Biology 27:1, pages 15-26.
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