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REVIEW ARTICLE

Matrix metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation

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Pages 306-321 | Published online: 08 Jul 2009

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Heta Dinesh Bhatt, Lorne M Golub, Hsi-Ming Lee, Jihwan Kim, Thomas Zimmerman, Jie Deng, Houlin Hong, Francis Johnson & Ying Gu. (2023) Efficacy of a Novel Pleiotropic MMP-Inhibitor, CMC2.24, in a Long-Term Diabetes Rat Model with Severe Hyperglycemia-Induced Oral Bone Loss. Journal of Inflammation Research 16, pages 779-792.
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Tuomo Karila, Taina Tervahartiala, Beniamin Cohen & Timo Sorsa. (2022) The collagenases: are they tractable targets for preventing cartilage destruction in osteoarthritis?. Expert Opinion on Therapeutic Targets 26:2, pages 93-105.
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Timo Sorsa, Vaibhav Sahni, Nurcan Buduneli, Shipra Gupta, Ismo T. Räisänen, Lorne M. Golub, Hsi-Ming Lee, Tommi Pätilä, Nagihan Bostanci, Jukka Meurman, Pirjo Pärnänen, Solomon O. Nwhator, Mohita Singla & Krishan Gauba. (2021) Active matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) in the COVID-19 pandemic. Expert Review of Proteomics 18:8, pages 707-717.
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Mutlu Keskin, Hanna Lähteenmäki, Nilminie Rathnayake, Ismo T. Räisänen, Taina Tervahartiala, Pirjo Pärnänen, Ahmet Murat Şenışık, Didem Karaçetin, Ayben Yentek Balkanay, Pia Heikkilä, Jaana Hagström, Jaana Rautava, Caj Haglund, Ulvi Kahraman Gursoy, Angelika Silbereisen, Nagihan Bostanci & Timo Sorsa. (2020) Active matrix metalloproteinase-8 and interleukin-6 detect periodontal degeneration caused by radiotherapy of head and neck cancer: a pilot study. Expert Review of Proteomics 17:10, pages 777-784.
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Heidi Kruit, Oskari Heikinheimo, Timo Sorsa, Juuso Juhila, Jorma Paavonen & Leena Rahkonen. (2018) Cervical biomarkers as predictors of successful induction of labour by Foley catheter. Journal of Obstetrics and Gynaecology 38:7, pages 927-932.
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Leena Äyräväinen, Anna Maria Heikkinen, Antti Kuuliala, Kirsi Ahola, Riitta Koivuniemi, Leena Laasonen, Eeva Moilanen, Mari Hämäläinen, Taina Tervahartiala, Jukka H. Meurman, Marjatta Leirisalo-Repo & Timo Sorsa. (2018) Inflammatory biomarkers in saliva and serum of patients with rheumatoid arthritis with respect to periodontal status. Annals of Medicine 50:4, pages 333-344.
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Chen Fan, Xufang Zhang & Zee Upton. (2018) Anti-inflammatory effects of shikonin in human periodontal ligament cells. Pharmaceutical Biology 56:1, pages 415-421.
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A Beklen. (2017) Effects of IL-13 on TGF-β and MMP-1 in periodontitis. Biotechnic & Histochemistry 92:5, pages 374-380.
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Rui Yang, Bo-Chuan Yuan, Yong-Sheng Ma, Shan Zhou & Ying Liu. (2017) The anti-inflammatory activity of licorice, a widely used Chinese herb. Pharmaceutical Biology 55:1, pages 5-18.
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Patricia Hernández-Ríos, Marcela Hernández, Mauricio Garrido, Taina Tervahartiala, Jussi M Leppilahti, Heidi Kuula, Anna Maria Heikkinen, Päivi Mäntylä, Nilminie Rathnayake, Solomon Nwhator & Timo Sorsa. (2016) Oral fluid matrix metalloproteinase (MMP)-8 as a diagnostic tool in chronic periodontitis. Metalloproteinases in Medicine 3, pages 11-18.
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Noemi Cifani, Maria Proietta, Luigi Tritapepe, Cira Di Gioia, Livia Ferri, Maurizio Taurino & Flavia Del Porto. (2015) Stanford-A acute aortic dissection, inflammation, and metalloproteinases: A review. Annals of Medicine 47:6, pages 441-446.
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Marko Lempinen, Ilaana Lyytinen, Arno Nordin, Taina Tervahartiala, Heikki Mäkisalo, Timo Sorsa & Helena Isoniemi. (2013) Prognostic value of serum MMP-8, -9 and TIMP-1 in patients with hepatocellular carcinoma. Annals of Medicine 45:7, pages 482-487.
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Laura Mäkitalo, Hanne Rintamäki, Taina Tervahartiala, Timo Sorsa & Kaija-Leena Kolho. (2012) Serum MMPs 7–9 and their inhibitors during glucocorticoid and anti-TNF-α therapy in pediatric inflammatory bowel disease. Scandinavian Journal of Gastroenterology 47:7, pages 785-794.
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Fares Zeidán-Chuliá, José L. Rybarczyk-Filho, Mervi Gursoy, Eija Könönen, Veli-Jukka Uitto, Orhan V. Gursoy, Lutfu Cakmakci, José C. F. Moreira & Ulvi K. Gursoy. (2012) Bioinformatical and in vitro approaches to essential oil-induced matrix metalloproteinase inhibition. Pharmaceutical Biology 50:6, pages 675-686.
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Anneli Lauhio, Szilard Rezes, Taina Tervahartiala, Istvan Sziklai, Anne Pitkäranta & Timo Sorsa. (2012) Matrix metalloproteinase-8/collagenase-2 in childhood otitis media with effusion. Annals of Medicine 44:1, pages 93-99.
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Hilpi Rautelin, Taina Tervahartiala, Anneli Lauhio, Timo Sorsa & Kaija-Leena Kolho. (2010) Assessment of systemic matrix metalloproteinase and their regulator response in children with Helicobacter pylori gastritis. Scandinavian Journal of Clinical and Laboratory Investigation 70:7, pages 492-496.
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Jun-ichi Suzuki, Norio Aoyama, Masahito Ogawa, Yasunobu Hirata, Yuichi Izumi, Ryozo Nagai & Mitsuaki Isobe. (2010) Periodontitis and cardiovascular diseases. Expert Opinion on Therapeutic Targets 14:10, pages 1023-1027.
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Juan Pablo Loyola-Rodriguez, Rita Elizabeth Martinez-Martinez, Carlos Abud-Mendoza, Nuria Patiño-Marin & Gregory J. Seymour. (2010) Rheumatoid arthritis and the role of oral bacteria. Journal of Oral Microbiology 2:1.
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Hilpi I. Rautelin, Aino M. Oksanen, Lea I. Veijola, Pentti I. Sipponen, Taina I. Tervahartiala, Timo A. Sorsa & Anneli Lauhio. (2009) Enhanced systemic matrix metalloproteinase response in Helicobacter pylori gastritis. Annals of Medicine 41:3, pages 208-215.
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Hans-Peter Horz & Georg Conrads. (2007) Diagnosis and anti-infective therapy of periodontitis. Expert Review of Anti-infective Therapy 5:4, pages 703-715.
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