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Annals of Medicine Volume 41, 2009 - Issue 4
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Original Article

Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: A meta-analysis of randomized controlled trials

Yun-Tao Zhao Department of Cardiology, Peking University People's Hospital, Beijing, China
,
Qiang Chen Center for Public Health Surveillance and Information Service, Chinese Center for Disease Control and Prevention, Beijing, China
,
Ya-Xun Sun Department of Cardiology, Peking University People's Hospital, Beijing, China
,
Xue-Bin Li Department of Cardiology, Peking University People's Hospital, Beijing, China
,
Ping Zhang Department of Cardiology, Peking University People's Hospital, Beijing, China
,
Yuan Xu Department of Cardiology, Peking University People's Hospital, Beijing, China
&
Ji-Hong Guo Department of Cardiology, Peking University People's Hospital, Beijing, ChinaCorrespondence[email protected]
, MD show all
Pages 301-310 | Received 30 Mar 2008, Published online: 08 Jul 2009

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Stefano Marventano, Paulina Kolacz, Sabrina Castellano, Fabio Galvano, Silvio Buscemi, Antonio Mistretta & Giuseppe Grosso. (2015) A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: does the ratio really matter?. International Journal of Food Sciences and Nutrition 66:6, pages 611-622.
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Andy H Lee & Naoko Hiramatsu. (2011) Role of n-3 series polyunsaturated fatty acids in cardiovascular disease prevention. Nutrition and Dietary Supplements 3, pages 93-100.
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Articles from other publishers (60)

Mohammad A. Alfhili, Jawaher Alsughayyir, Ahmed Basudan, Mohammed Alfaifi, Zuhier A. Awan, Mohammed R. Algethami & Yazeed A. Al-Sheikh. (2023) Blood indices of omega-3 and omega-6 polyunsaturated fatty acids are altered in hyperglycemia. Saudi Journal of Biological Sciences 30:3, pages 103577.
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Ivana Djuricic & Philip C. Calder. (2023) Pros and Cons of Long-Chain Omega-3 Polyunsaturated Fatty Acids in Cardiovascular Health. Annual Review of Pharmacology and Toxicology 63:1, pages 383-406.
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Antonis S. Manolis, Theodora A. Manolis, Antonis A. Manolis & Helen Melita. (2022) Diet and Sudden Death: How to Reduce the Risk. Current Vascular Pharmacology 20:5, pages 383-408.
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Austin Angelotti, Deena B. Snoke, Kate Ormiston, Rachel M. Cole, Kamil Borkowski, John W. Newman, Tonya S. Orchard & Martha A. Belury. (2022) Potential Cardioprotective Effects and Lipid Mediator Differences in Long-Chain Omega-3 Polyunsaturated Fatty Acid Supplemented Mice Given Chemotherapy. Metabolites 12:9, pages 782.
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Dimitrios Tsartsalis, Dafni Korela, Lars O. Karlsson, Emmanouil Foukarakis, Anneli Svensson, Aris Anastasakis, Dimitrios Venetsanos, Constantina Aggeli, Costas Tsioufis, Frieder Braunschweig, Elena Dragioti & Emmanouil Charitakis. (2022) Risk and Protective Factors for Sudden Cardiac Death: An Umbrella Review of Meta-Analyses. Frontiers in Cardiovascular Medicine 9.
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A. V. Susekov. (2021) Omega-3 Polyunsaturated Fatty Acids in Patients with Hypertriglyceridemias and Atherosclerosis. Kardiologiia 61:6, pages 88-96.
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Maria Luz Fernandez, Sarah A. Blomquist, Brian Hallmark & Floyd H. Chilton. (2021) Omega-3 Supplementation and Heart Disease: A Population-Based Diet by Gene Analysis of Clinical Trial Outcomes. Nutrients 13:7, pages 2154.
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Asmaa S Abdelhamid, Tracey J Brown, Julii S Brainard, Priti Biswas, Gabrielle C Thorpe, Helen J Moore, Katherine HO Deane, Carolyn D Summerbell, Helen V Worthington, Fujian Song & Lee Hooper. (2020) Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews 2020:3.
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Jacqueline K. Innes & Philip C. Calder. (2020) Marine Omega-3 (N-3) Fatty Acids for Cardiovascular Health: An Update for 2020. International Journal of Molecular Sciences 21:4, pages 1362.
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Sho-ichi Yamagishi & Takanori Matsui. (2019) Effects of Dietary Intake and Supplementation of Fatty Acids on Cardiometabolic Disorders in Humans: a Lesson from a Large Number of Meta-Analyses. Letters in Drug Design & Discovery 16:10, pages 1138-1145.
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Trevor A. Mori. (2018) Reprint of: Marine OMEGA-3 fatty acids in the prevention of cardiovascular disease. Fitoterapia 126, pages 8-15.
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Trevor A. Mori. (2017) Marine OMEGA-3 fatty acids in the prevention of cardiovascular disease. Fitoterapia 123, pages 51-58.
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Ankur Sethi, Anurag Bajaj, Sandeep Khosla & Rohit R. Arora. (2016) Statin Use Mitigate the Benefit of Omega-3 Fatty Acids Supplementation—A Meta-Regression of Randomized Trials. American Journal of Therapeutics 23:3, pages e737-e748.
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J. R. Lupton, J. B. Blumberg, M. L?Abbe, M. LeDoux, H. B. Rice, C. von Schacky, A. Yaktine & J. C. Griffiths. (2016) Nutrient reference value: non-communicable disease endpoints?a conference report. European Journal of Nutrition 55:S1, pages 1-10.
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Jennifer E Enns, Azadeh Yeganeh, Ryan Zarychanski, Ahmed M Abou-Setta, Carol Friesen, Peter Zahradka & Carla G Taylor. (2014) The impact of omega-3 polyunsaturated fatty acid supplementation on the incidence of cardiovascular events and complications in peripheral arterial disease: a systematic review and meta-analysis. BMC Cardiovascular Disorders 14:1.
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Peter L. McLennan. (2014) Cardiac physiology and clinical efficacy of dietary fish oil clarified through cellular mechanisms of omega-3 polyunsaturated fatty acids. European Journal of Applied Physiology 114:7, pages 1333-1356.
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. (2012) n–3 Fatty Acids and Cardiovascular Outcomes in Patients with Dysglycemia. New England Journal of Medicine 367:4, pages 309-318.
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Hosen KiatYu Sun BinSuzanne GrantDennis Hsu‐Tung Chang. (2011) Complementary medicine use in cardiovascular disease: a clinician's viewpoint. Medical Journal of Australia 195:11-12, pages 654-656.
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Qi Chen, Liu-Quan Cheng, Tie-Hui Xiao, Yu-Xiao Zhang, Mei Zhu, Ran Zhang, Ke Li, Yu Wang & Yang Li. (2011) Effects of Omega-3 Fatty Acid for Sudden Cardiac Death Prevention in Patients with Cardiovascular Disease: A Contemporary Meta-Analysis of Randomized, Controlled Trials. Cardiovascular Drugs and Therapy 25:3, pages 259-265.
Crossref
Gustav Dobos & Iven Tao. (2011) The model of western integrative medicine: The role of Chinese medicine. Chinese Journal of Integrative Medicine 17:1, pages 11-20.
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Naranjan S. Dhalla, Adriana Adameova & Meera Kaur. (2010) Role of catecholamine oxidation in sudden cardiac death. Fundamental & Clinical Pharmacology 24:5, pages 539-546.
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Ameer Y. Taha, W. McIntyre Burnham & Stéphane Auvin. (2010) Polyunsaturated fatty acids and epilepsy. Epilepsia 51:8, pages 1348-1358.
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Brad McEwen, Marie-Christine Morel-Kopp, Geoffrey Tofler & Christopher Ward. (2010) Effect of Omega-3 Fish Oil on Cardiovascular Risk in Diabetes. The Diabetes Educator 36:4, pages 565-584.
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George E. BillmanYoshinori Nishijima, Andriy E. BelevychDmitry TerentyevYing XuKaylan M. HaizlipMichelle M. MonaskyNitisha HiranandaniWilliam S. Harris, Sandor GyorkeCynthia A. Carnes & Paul M. L. Janssen. (2010) Effects of dietary omega–3 fatty acids on ventricular function in dogs with healed myocardial infarctions: in vivo and in vitro studies. American Journal of Physiology-Heart and Circulatory Physiology 298:4, pages H1219-H1228.
Crossref
. (2010) Current World Literature. Current Opinion in Clinical Nutrition & Metabolic Care 13:2, pages 215-221.
Crossref
Gustav Dobos. (2009) Integrative Medicine – Medicine of the future or ‘Old Wine in New Skins’?. European Journal of Integrative Medicine 1:3, pages 109-115.
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John G.T. Augoustides & Prakash Patel. (2009) Recent Advances in Perioperative Medicine: Highlights From the Literature for the Cardiothoracic and Vascular Anesthesiologist. Journal of Cardiothoracic and Vascular Anesthesia 23:3, pages 430-436.
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Robert K. McNamara. (2009) Membrane Omega-3 Fatty Acid Deficiency as a Preventable Risk Factor for Comorbid Coronary Heart Disease in Major Depressive Disorder. Cardiovascular Psychiatry and Neurology 2009, pages 1-13.
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