Advanced search
Publication Cover
International Reviews of Immunology Volume 27, 2008 - Issue 5
Submit an article Journal homepage
992
Views
57
CrossRef citations to date
0
Altmetric
Special Topic: NF-κB, Immunity and Cancer

G Protein–Coupled Receptor Connectivity to NF-κB in Inflammation and Cancer

Christopher C. Fraser Arlington, Massachusetts, USA
Pages 320-350 | Published online: 03 Aug 2009

Citations (57)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Yingnan Ye, Pengpeng Liu, Yue Wang, Hui Li, Feng Wei, Yanan Cheng, Lei Han & Jinpu Yu. (2016) Neurotensin, a Novel Messenger to Cross-Link Inflammation and Tumor Invasion via Epithelial-Mesenchymal Transition Pathway. International Reviews of Immunology 35:4, pages 340-350.
Read now

Articles from other publishers (56)

Kenneth T. Bogen. (2023) Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model. Environmental Research 230, pages 115047.
Crossref
Gangqi Yang, Hongyan Li, Zheng Dong, Kai Deng & Yinying Lu. (2023) Nucleophosmin 1 associating with engulfment and cell motility protein 1 regulates hepatocellular carcinoma cell chemotaxis and metastasis. Open Medicine 18:1.
Crossref
Polash Kumar Biswas, Sang Rok Park, Jongyub An, Kyung Min Lim, Ahmed Abdal Dayem, Kwonwoo Song, Hye Yeon Choi, Yujin Choi, Kyoung Sik Park, Hyun Jin Shin, Aram Kim, Minchan Gil, Subbroto Kumar Saha & Ssang-Goo Cho. (2023) The Orphan GPR50 Receptor Regulates the Aggressiveness of Breast Cancer Stem-like Cells via Targeting the NF-kB Signaling Pathway. International Journal of Molecular Sciences 24:3, pages 2804.
Crossref
Zhenlong Chen, Jacob M. Haus, Luisa A. DiPietro, Timothy J. Koh & Richard D. Minshall. (2023) Neutralization of excessive CCL28 improves wound healing in diabetic mice. Frontiers in Pharmacology 14.
Crossref
Zahra Abedi Kichi, Lucia Natarelli, Saeed Sadeghian, Mohammad ali Boroumand, Mehrdad Behmanesh & Christian Weber. (2022) Orphan GPR26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients. Biomedicines 10:7, pages 1736.
Crossref
Siyuan Song, Jiayu Zhou, Ye Li, Jiatong Liu, Jingzhan Li & Peng Shu. (2022) Network pharmacology and experimental verification based research into the effect and mechanism of Aucklandiae Radix–Amomi Fructus against gastric cancer. Scientific Reports 12:1.
Crossref
Yamina A. Berchiche & Terence E. Hébert. (2022) Editorial: GPCR and G Protein-Mediated Signalling Events in the Nervous System. Frontiers in Cellular Neuroscience 16.
Crossref
Chia‐Chia Chao, Wei‐Fang Lee, Shih‐Wei Wang, Po‐Chun Chen, Ayaho Yamamoto, Tsung‐Ming Chang, Shun‐Long Weng & Ju‐Fang Liu. (2021) CXC chemokine ligand‐13 promotes metastasis via CXCR5‐dependent signaling pathway in non‐small cell lung cancer. Journal of Cellular and Molecular Medicine 25:19, pages 9128-9140.
Crossref
Miguel Quiros. (2020) Therapeutic Opportunities for Repair GPCRs during Intestinal Mucosal Wound Healing. Trends in Molecular Medicine 26:11, pages 971-974.
Crossref
Jianhua Rao, Chao Yang, Shikun Yang, Hao Lu, Yuanchang Hu, Ling Lu, Feng Cheng & Xuehao Wang. (2020) Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex. International Immunology 32:5, pages 321-334.
Crossref
Xia Fan, Luqing He, Qiaoxia Dai, Junhong He, Xiangjuan Chen, Xiaozhen Dai, Chi Zhang, Da Sun, Xue Meng, Shiyue Sun, Jiameng Huang, Jun Chen, Lin Lin, Liangmiao Chen, Yi Tan & Xiaoqing Yan. (2020) Interleukin‐1β augments the angiogenesis of endothelial progenitor cells in an NF‐κB/CXCR7‐dependent manner. Journal of Cellular and Molecular Medicine 24:10, pages 5605-5614.
Crossref
Yecheng Wang, Hongyan Li & Fei Li. (2020) ELMO2 association with G α i2 regulates pancreatic cancer cell chemotaxis and metastasis . PeerJ 8, pages e8910.
Crossref
Wei Kiang Lim, Xiaoran Chai, Sujoy Ghosh, Debleena Ray, Mei Wang, Suhail Ahmed Kabeer Rasheed & Patrick J. Casey. (2019) Gα-13 induces CXC motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB. Journal of Biological Chemistry 294:48, pages 18192-18206.
Crossref
Seyed Abbas Mirzaei, Farideh Dinmohammadi, Akram Alizadeh & Fatemeh Elahian. (2019) Inflammatory pathway interactions and cancer multidrug resistance regulation. Life Sciences 235, pages 116825.
Crossref
L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui & X. Zhang. (2018) Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese. British Journal of Dermatology.
Crossref
Ying ShaoGayani NanayakkaraJiali ChengRamon CuetoWilliam Y. YangJoon-Young ParkHong WangXiaofeng Yang. (2018) Lysophospholipids and Their Receptors Serve as Conditional DAMPs and DAMP Receptors in Tissue Oxidative and Inflammatory Injury. Antioxidants & Redox Signaling 28:10, pages 973-986.
Crossref
Haojun Yang, Haoming Zhou, Lin Zhuang, Johan Auwerx, Kristina Schoonjans, Xuehao Wang, Cheng Feng & Ling Lu. (2016) Plasma membrane‐bound G protein–coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll‐like receptor 4 signaling in mice. Liver Transplantation 23:1, pages 63-74.
Crossref
Chengzhi Chen, Shiyan Gu, Xuejun Jiang & Zunzhen Zhang. (2016) Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line. Environmental Toxicology 31:12, pages 1819-1833.
Crossref
Zhiwei Ang, Jun Zhi Er, Nguan Soon Tan, Jinhua Lu, Yih-Cherng Liou, Johannes Grosse & Jeak Ling Ding. (2016) Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists. Scientific Reports 6:1.
Crossref
Lin Zhuang, Ye Fan, Ling Lu, Wenbin Ding, Chuangye Ni, Xuehao Wang, Feng Zhang & Jianhua Rao. (2016) Ischemic Preconditioning protects hepatocytes from ischemia-reperfusion injury via TGR5-mediated anti-apoptosis. Biochemical and Biophysical Research Communications 473:4, pages 966-972.
Crossref
Ye Liu, Yang Liu, Dan Xu & Jing Li. (2015) Latanoprost-induced Cytokine and Chemokine Release From Human Tenon?s Capsule Fibroblasts. Journal of Glaucoma 24:9, pages 635-641.
Crossref
Miriam C. Peeters, Michiel Fokkelman, Bob Boogaard, Kristoffer L. Egerod, Bob van de Water, Ad P. IJzerman & Thue W. Schwartz. (2015) The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration. Cellular Signalling 27:12, pages 2579-2588.
Crossref
Ludmila D. Lukyanova & Yulia I. Kirova. (2015) Mitochondria-controlled signaling mechanisms of brain protection in hypoxia. Frontiers in Neuroscience 9.
Crossref
Hong Wang, Gautam Sethi, Weng-Keong Loke & Meng-Kwoon Sim. (2015) Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action. PLOS ONE 10:9, pages e0138009.
Crossref
Sung Hye Kim, David A. MacIntyre, Maria Firmino Da Silva, Andrew M. Blanks, Yun S. Lee, Steven Thornton, Phillip R. Bennett & Vasso Terzidou. (2015) Oxytocin activates NF-?B-mediated inflammatory pathways in human gestational tissues. Molecular and Cellular Endocrinology 403, pages 64-77.
Crossref
Jacques RobertJacques Robert. 2015. Textbook of Cell Signalling in Cancer. Textbook of Cell Signalling in Cancer 77 92 .
John R RaymondJrJr, Kathryn M Appleton, Jennifer Y Pierce & Yuri K Peterson. (2014) Suppression of GNAI2 message in ovarian cancer. Journal of Ovarian Research 7:1.
Crossref
Nicoline Y. den Breems, Lan K. Nguyen & Don Kulasiri. (2014) Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cells. Biosystems 126, pages 27-40.
Crossref
M Rodriguez, W Luo, J Weng, L Zeng, Z Yi, S Siwko & M Liu. (2014) PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB. Oncogenesis 3:8, pages e114-e114.
Crossref
Huan Qiao, Yan Liu, Ruth A. Veach, Lukasz Wylezinski & Jacek Hawiger. (2014) The Adaptor CRADD/RAIDD Controls Activation of Endothelial Cells by Proinflammatory Stimuli. Journal of Biological Chemistry 289:32, pages 21973-21983.
Crossref
Kathryn M. Appleton, Kevin J. Bigham, Christopher C. Lindsey, Starr Hazard, Jonel Lirjoni, Stuart Parnham, Mirko Hennig & Yuri K. Peterson. (2014) Development of inhibitors of heterotrimeric Gαi subunits. Bioorganic & Medicinal Chemistry 22:13, pages 3423-3434.
Crossref
Anat Lucki, Ehud Klein, Rachel Karry & Dorit Ben-Shachar. (2013) Dexamethasone in the presence of desipramine enhances MAPK/ERK1/2 signaling possibly via its interference with β-arrestin. Journal of Neural Transmission 121:3, pages 289-298.
Crossref
Boon Chin Heng, Dominique Aubel & Martin Fussenegger. (2013) An overview of the diverse roles of G-protein coupled receptors (GPCRs) in the pathophysiology of various human diseases. Biotechnology Advances 31:8, pages 1676-1694.
Crossref
Shiou-Ling Jian, Hsin-Yi Hsieh, Chun-Ta Liao, Tzu-Chen Yen, Shu-Wei Nien, Ann-Joy Cheng & Jyh-Lyh Juang. (2013) Gα12 Drives Invasion of Oral Squamous Cell Carcinoma through Up-Regulation of Proinflammatory Cytokines. PLoS ONE 8:6, pages e66133.
Crossref
J?nos G. Filep & Driss El Kebir. (2012) Models of G-protein-coupled receptor-dependent cardiovascular inflammation. Drug Discovery Today: Disease Models 9:3, pages e129-e135.
Crossref
Sarah Gerlo, Ron Kooijman, Ilse M. Beck, Krzysztof Kolmus, Anneleen Spooren & Guy Haegeman. (2011) Cyclic AMP: a selective modulator of NF-κB action. Cellular and Molecular Life Sciences 68:23, pages 3823-3841.
Crossref
Yan-Dong Wang, Wei-Dong Chen, Donna Yu, Barry M. Forman & Wendong Huang. (2011) The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice. Hepatology 54:4, pages 1421-1432.
Crossref
Mingfeng Zhang, Hongqi Teng, Jueping Shi & Yanding Zhang. (2011) Disruption of β-arrestins blocks glucocorticoid receptor and severely retards lung and liver development in mice. Mechanisms of Development 128:7-10, pages 368-375.
Crossref
Eugene Teck‐Leong Ng, Meng‐Kwoon Sim & Weng‐Keong Loke. (2010) Protective actions of des‐aspartate‐angiotensin I in mice model of CEES‐induced lung intoxication. Journal of Applied Toxicology 31:6, pages 568-578.
Crossref
Christofer S. Tautermann. (2011) The use of G-protein coupled receptor models in lead optimization. Future Medicinal Chemistry 3:6, pages 709-721.
Crossref
Mark J Millan. (2011) MicroRNA in the regulation and expression of serotonergic transmission in the brain and other tissues. Current Opinion in Pharmacology 11:1, pages 11-22.
Crossref
Alexander Gosslau, David Li En Jao, Mou‐Tuan Huang, Chi‐Tan Ho, Dave Evans, Nancy E. Rawson & Kuang Yu Chen. (2011) Effects of the black tea polyphenol theaflavin‐2 on apoptotic and inflammatory pathways in vitro and in vivo . Molecular Nutrition & Food Research 55:2, pages 198-208.
Crossref
Rosamaria Lappano & Marcello Maggiolini. (2010) G protein-coupled receptors: novel targets for drug discovery in cancer. Nature Reviews Drug Discovery 10:1, pages 47-60.
Crossref
Linda M. McAllister-Lucas, Xiaohong Jin, Shufang Gu, Katy Siu, Scott McDonnell, Jürgen Ruland, Phillip C. Delekta, Matthew Van Beek & Peter C. Lucas. (2010) The CARMA3-Bcl10-MALT1 Signalosome Promotes Angiotensin II-dependent Vascular Inflammation and Atherogenesis. Journal of Biological Chemistry 285:34, pages 25880-25884.
Crossref
Guy Laureys, Ralph Clinckers, Sarah Gerlo, Anneleen Spooren, Nadine Wilczak, Ron Kooijman, Ilse Smolders, Yvette Michotte & Jacques De Keyser. (2010) Astrocytic β2-adrenergic receptors: From physiology to pathology. Progress in Neurobiology 91:3, pages 189-199.
Crossref
Anneleen Spooren, Ron Kooijman, Béatrice Lintermans, Kathleen Van Craenenbroeck, Linda Vermeulen, Guy Haegeman & Sarah Gerlo. (2010) Cooperation of NFκB and CREB to induce synergistic IL-6 expression in astrocytes. Cellular Signalling 22:5, pages 871-881.
Crossref
Jiong Deng, Junya Fujimoto, Xiao-Feng Ye, Tao-Yan Men, Carolyn S. Van Pelt, Yu-Long Chen, Xiao-Feng Lin, Humam Kadara, Qingguo Tao, Dafna Lotan & Reuben Lotan. (2010) Knockout of the Tumor Suppressor Gene Gprc5a in Mice Leads to NF-κB Activation in Airway Epithelium and Promotes Lung Inflammation and Tumorigenesis . Cancer Prevention Research 3:4, pages 424-437.
Crossref
Mingfeng Zhang, Xiaosong Liu, Yanding Zhang & Jian Zhao. (2010) Loss of ?arrestin1 and ?arrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice. Developmental Biology 339:2, pages 407-417.
Crossref
A. J. Español, N. Goren, M. L. Ribeiro & María Elena Sales. (2009) Nitric oxide synthase 1 and cyclooxygenase-2 enzymes are targets of muscarinic activation in normal and inflamed NIH3T3 cells. Inflammation Research 59:3, pages 227-238.
Crossref
Syed M. Ahmed, Avais M. Daulat, Alexandre Meunier & Stephane Angers. (2010) G Protein βγ Subunits Regulate Cell Adhesion through Rap1a and Its Effector Radil. Journal of Biological Chemistry 285:9, pages 6538-6551.
Crossref
Yue Zhang. (2010) Article Commentary: Rough Set Soft Computing Cancer Classification and Network: One Stone, Two Birds. Cancer Informatics 9, pages CIN.S4874.
Crossref
Veronica Sanchez Freire, Fiona C. Burkhard, Thomas M. Kessler, Annette Kuhn, Annette Draeger & Katia Monastyrskaya. (2010) MicroRNAs May Mediate the Down-Regulation of Neurokinin-1 Receptor in Chronic Bladder Pain Syndrome. The American Journal of Pathology 176:1, pages 288-303.
Crossref
Laura V. González Bosc, Thomas Resta, Benjimen Walker & Nancy L. Kanagy. (2010) Mechanisms of intermittent hypoxia induced hypertension. Journal of Cellular and Molecular Medicine 14:1-2, pages 3-17.
Crossref
Jacques RobertJacques Robert. 2010. Signalisation cellulaire et cancer. Signalisation cellulaire et cancer 91 102 .
Susan S. Percival. 2010. Dietary Components and Immune Function. Dietary Components and Immune Function 283 295 .
Kenneth T. Bogen. (2022) Ultrasensitive Dose-Response for Asbestos Cancer Risk Implied by New Inflammation-Mutation Model. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.