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Research Article

ACUTE LYMPHOBLASTIC LEUKEMIA AND KLINEFELTER SYNDROME IN CHILDREN: Two Cases and Review of the Literature

, MD, , MD, , MD, , MD & , MD
Pages 621-626 | Published online: 09 Jul 2009

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Guang-Quan Zhao & Jonathan E Dowell. (2012) Hematologic malignancies associated with germ cell tumors. Expert Review of Hematology 5:4, pages 427-437.
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Eigil Kjeldsen. (2022) Congenital Aneuploidy in Klinefelter Syndrome with B-Cell Acute Lymphoblastic Leukemia Might Be Associated with Chromosomal Instability and Reduced Telomere Length. Cancers 14:9, pages 2316.
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Patrick A. BrownBijal ShahAnjali AdvaniPatricia AounMichael W. BoyerPatrick W. BurkeDaniel J. DeAngeloShira DinnerAmir T. FathiJordan GauthierNitin JainSuzanne KirbyMichaela LiedtkeMark LitzowAaron LoganSelina LugerLori J. ManessStephanie MassaroRyan J. MattisonWilliam MayOlalekan OluwoleJae ParkAmanda PrzespolewskiSravanti RangarajuJeffrey E. RubnitzGeoffrey L. UyMadhuri VusirikalaMatthew Wieduwilt, Beth LynnRyan A. BerardiDeborah A. Freedman-CassMallory Campbell. (2021) Acute Lymphoblastic Leukemia, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network 19:9, pages 1079-1109.
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Alexsandra P. Rojas, Diana V. Vo, Lance Mwangi, Shabnam Rehman & Alan N. Peiris. (2020) Oncologic manifestations of Klinefelter syndrome. Hormones 19:4, pages 497-504.
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Rachel E. Rau, Andrew J. Carroll, Nyla A. Heerema, Lesley Arland, William L. Carroll, Naomi J. Winick, Elizabeth A. Raetz, Mignon L. Loh, Wenjian Yang, Mary V. Relling, Yunfeng Dai, Meenakshi Devidas & Stephen P. Hunger. (2017) Klinefelter syndrome and 47,XYY syndrome in children with B cell acute lymphoblastic leukaemia. British Journal of Haematology 179:5, pages 843-846.
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Amy Berrington de Gonzalez, Jane A Salotti, Kieran McHugh, Mark P Little, Richard W Harbron, Choonsik Lee, Estelle Ntowe, Melissa Z Braganza, Louise Parker, Preetha Rajaraman, Charles Stiller, Douglas R Stewart, Alan W Craft & Mark S Pearce. (2016) Relationship between paediatric CT scans and subsequent risk of leukaemia and brain tumours: assessment of the impact of underlying conditions. British Journal of Cancer 114:4, pages 388-394.
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Marla M. Jalbut, Aliyah R. Sohani, Paola Dal Cin, Robert P. Hasserjian, Jenna A. Moran, Andrew M. Brunner & Amir T. Fathi. (2015) Acute myeloid leukemia in a patient with constitutional 47,XXY karyotype. Leukemia Research Reports 4:1, pages 28-30.
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Shirley V. Hodgson, William D. Foulkes, Charis Eng & Eamonn R. MaherShirley V. Hodgson, William D. Foulkes, Charis Eng & Eamonn R. Maher. 2014. A Practical Guide to Human Cancer Genetics. A Practical Guide to Human Cancer Genetics 219 359 .
Cara B. Cimmino & Robert D. Oates. 2013. Fertility Preservation in Male Cancer Patients. Fertility Preservation in Male Cancer Patients 58 63 .
. 2013. Fertility Preservation in Male Cancer Patients. Fertility Preservation in Male Cancer Patients 39 103 .
Gönül Ogur, Feride Duru, Emel Ozyurek & Tunc Fisgin. (2012) t(6;9)(p23;q34) Presenting Acute Myeloid Leukemia in a Child With an Unsuspected 45,X/46,X,derY [?t(Yp;Yq)] Chromosomal Constitution. Journal of Pediatric Hematology/Oncology 34:6, pages e237-e240.
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Hatem Bellaaj, Halima Sennana Sandi, Hassen Kammoun, Choumous Kallel, Olfa Kassar & Moez Elloumi. (2009) Syndrome de Klinefelter révélé par une leucémie aiguë myéloblastique. La Presse Médicale 38:6, pages 1019-1022.
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Yulia V. Olshanskaya, Alla I. Udovichenko, Lubov Yu Kolosova & Alina V. Kokhno. (2009) Myelodysplastic syndrome with monosomy 7 in a patient with XY gonadal dysgenesis (incomplete testicular feminization). Cancer Genetics and Cytogenetics 191:2, pages 113-114.
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Yasemin Isik Balci, Tuba Turul, Ghaniya Daar, Sema Anak, Omer Devecioglu, Ilhan Tezcan & Duygu Uckan Cetinkaya. (2008) Hematopoietic stem cell transplantation from a donor with Klinefelter syndrome for Wiskott-Aldrich syndrome. Pediatric Transplantation 12:5, pages 597-599.
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Said Ismail, Wafa Qubbaj, Mona Kilani, Miza Hijazi, Amid Abdelnour, Mohammed S. Al-khateeb & Abdalla Awidi. (2007) Successful bone marrow transplantation for treatment of chronic myeloid leukemia from a donor with mosaic klinefelter syndrome. International Journal of Hematology 86:3, pages 287-288.
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M. L. Garrè, V. Capra, E. Di Battista, L. Giampietri, P. Nozza, A. Raso, A. Pezzolo, A. Rossi, C. Milanaccio, M. Pavanello & A. Naselli. (2006) Genetic abnormalities and CNS tumors: report of two cases of ependymoma associated with Klinefelter’s Syndrome (KS). Child's Nervous System 23:2, pages 219-223.
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Thomas M.K. Völkl, Thorsten Langer, Thomas Aigner, Holger Greess, Jörn D. Beck, Anita M. Rauch & Helmuth G. Dörr. (2006) Klinefelter syndrome and mediastinal germ cell tumors. American Journal of Medical Genetics Part A 140A:5, pages 471-481.
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