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Substance Abuse Volume 38, 2017 - Issue 4
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Quantitative testing of buprenorphine and norbuprenorphine to identify urine sample spiking during office-based opioid treatment

Joji SuzukiDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA;Department of Psychiatry, Brigham and Women's Faulkner Hospital, Boston, Massachusetts, USA;Harvard Medical School, Boston, Massachusetts, USACorrespondence[email protected]
, MD,
Jennifer ZinserDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA
, BSc,
Mohammed IssaDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA;Department of Psychiatry, Brigham and Women's Faulkner Hospital, Boston, Massachusetts, USA;Harvard Medical School, Boston, Massachusetts, USA;Department of Anesthesia, Brigham and Women's Faulkner Hospital, Boston, Massachusetts, USA
, MD &
Claudia RodriguezDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA;Department of Psychiatry, Brigham and Women's Faulkner Hospital, Boston, Massachusetts, USA;Harvard Medical School, Boston, Massachusetts, USA
, MD
Pages 504-507 | Published online: 15 Sep 2017

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Stephanie K. Rubel, Matthew Eisenstat, Jessica Wolff, Michael Calevski & Sasha Mital. (2023) Scope of, Motivations for, and Outcomes Associated with Buprenorphine Diversion in the United States: A Scoping Review. Substance Use & Misuse 58:5, pages 685-697.
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Andrea G. Barthwell, Jeffrey Allgaier & Kenneth Egli. (2018) Definitive urine drug testing in office-based opioid treatment: a literature review. Critical Reviews in Toxicology 48:10, pages 815-838.
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Nusrat Rahman, Abhilash Janardhanan, Sahil Shikalgar, Mohammad Aslam Pirkhan, James Canner, Christopher Skipwith & Md. Noor-E-Alam. Investigation of Simulated Adherence in Long-Term Buprenorphine/Naloxone Treatment Patients. Substance Use & Misuse 0:0, pages 1-5.
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Articles from other publishers (15)

Rebekah Rollston, Barbara Burke, Scott G. Weiner, Winifred Gallogly, Apryl D. Brandon, Robyn Carter & Brian Clear. (2023) Evaluation of urine drug screen falsification of results among patients with opioid use disorder receiving treatment in a telehealth model of care. Journal of Substance Use and Addiction Treatment 154, pages 209151.
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Jarratt D. Pytell, Penn Whitley, Steven D. Passik, William L. Bundy, Eric Dawson & Brendan Saloner. (2023) Association of Patients’ Direct Addition of Buprenorphine to Urine Drug Test Specimens With Clinical Factors in Opioid Use Disorder. JAMA Psychiatry 80:5, pages 459.
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Stuart Farquharson, Chetan Shende, Jenelle Newcomb, Ismene L. Petrakis & Albert J. Arias. (2023) Analysis of Drugs in Saliva of US Military Veterans Treated for Substance Use Disorders Using Supported Liquid Extraction and Surface-Enhanced Raman Spectral Analysis. Molecules 28:5, pages 2010.
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Hiroko Furo, Tony Lin, Yi Yuan Zhou & Sarah Abdelsayed. 2023. Advances and Challenges in Urine Laboratory Analysis [Working Title]. Advances and Challenges in Urine Laboratory Analysis [Working Title].
Hiroko Furo, Timothy Wiegand, Meenakshi Rani, Diane G Schwartz, Ross W Sullivan & Peter L Elkin. (2023) Association Between Buprenorphine Dose and the Urine “Norbuprenorphine” to “Creatinine” Ratio: Revised. Substance Abuse: Research and Treatment 17, pages 117822182311537.
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Xiaoyue Shan, Chengjian Cao & Bingsheng Yang. (2022) Analytical Approaches for the Determination of Buprenorphine, Methadone and Their Metabolites in Biological Matrices. Molecules 27:16, pages 5211.
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Hiroko Furo, Diane G Schwartz, Ross W Sullivan & Peter L Elkin. (2021) Buprenorphine Dosage and Urine Quantitative Buprenorphine, Norbuprenorphine, and Creatinine Levels in an Office-Based Opioid Treatment Program. Substance Abuse: Research and Treatment 15, pages 117822182110617.
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Christopher Tremonti & Paul S. Haber. 2021. Textbook of Addiction Treatment. Textbook of Addiction Treatment 637 654 .
Jill S. Warrington, Kaitlyn Booth, Gregory S. Warrington & Samuel Francis-Fath. (2020) Use of urinary naloxone levels in a single provider practice: a case study. Addiction Science & Clinical Practice 15:1.
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Jill S. Warrington, Gregory S. Warrington, Samuel Francis-Fath & John Brooklyn. (2020) Urinary Buprenorphine, Norbuprenorphine and Naloxone Concentrations and Ratios: Review and Potential Clinical Implications. Journal of Addiction Medicine 14:6, pages e344-e349.
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Jaime R. Ransohoff, Athena K. Petrides, Greg J. Piscitello, James G. Flood & Stacy E.F. Melanson. (2019) Urine is superior to oral fluid for detecting buprenorphine compliance in patients undergoing treatment for opioid addiction. Drug and Alcohol Dependence 203, pages 8-12.
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Lewei (Allison) Lin, Michelle R. Lofwall, Sharon L. Walsh, Adam J. Gordon & Hannah K. Knudsen. (2018) Perceptions and practices addressing diversion among US buprenorphine prescribers. Drug and Alcohol Dependence 186, pages 147-153.
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Stephen R. Holt, Joseph H. Donroe, Dana A. Cavallo & Jeanette M. Tetrault. (2018) Addressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder. Drug and Alcohol Dependence 186, pages 171-174.
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Anthony J. Accurso, Joshua D. Lee & Jennifer McNeely. (2017) High prevalence of urine tampering in an office-based opioid treatment practice detected by evaluating the norbuprenorphine to buprenorphine ratio. Journal of Substance Abuse Treatment 83, pages 62-67.
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Stephanie K. Rubel, Matthew Eisenstat, Jessica Wolff, Michael Calevski & Sasha Mital. (2022) Scope of, Motivations for, And Outcomes of Diverted Buprenorphine Among People Using Buprenorphine: A Scoping Review. SSRN Electronic Journal.
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